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UC Davis Comprehensive Cancer Center

Natalie J. Torok, M.D., M.Sc. View profile as PDF

Natalie J. Torok

Philosophy of Care

As a hepatologist and certified transplant hepatologist, I take care of patients with end-stage liver disease and also provide post-transplant care, including management of immunosuppression and treatment of post-transplant hepatitis C.

I see patients with nonalcoholic steatohepatitis (NASH), alcoholic liver disease, and autoimmune hepatitis. Also, we provide comprehensive care for patients with hepatocellular carcinoma.


Clinical Interests

Dr. Torok's clinical interests include; Gastroenterology and Hepatology, Transplant Hepatology, and Internal Medicine.


Research/Academic Interests

Our research focuses on wound healing and the basic mechanism of fibrosis in the liver.  We explore the pathways linking chronic liver injury, hepatocyte death and the activation of hepatic stellate cells, the principle fibrogenic cells of the liver.  

Our investigations led to the discovery of the important role of the NADPH oxidases in stellate cell activation and the production of oxidative radicals.  Based on our findings our aim is to explore the specific role of NADPH oxidases in non-alcoholic steatohepatitis and alcoholic liver disease.  Our ultimate goal is to move towards translational studies and to develop new therapies for patients with liver fibrosis and cirrhosis. 

Title:

Professor
Professor, VA Northern California Health Care System, Mather, CA

Specialty:

Gastroenterology and Hepatology, Internal Medicine, Transplant Hepatology

Division:

Gastroenterology and Hepatology

Clinic:

UC Davis Medical Group, Folsom
UC Davis Medical Group, Sacramento - Midtown

Center/Program Affiliation:

Address/Phone:

UC Davis Midtown Ambulatory Care Center
Midtown GI Clinic
3160 Folsom Blvd, Suite 3500
Sacramento, CA 95816
Driving Directions
Phone: 916-734-0779

UC Davis Medical Group - Folsom
271 Turn Pike Dr.
Folsom, CA 95630
Driving Directions
Phone: 916-985-9300

Additional Phone:

Physician Referrals: 800-4-UCDAVIS (800-482-3284)

Other Languages:

French, Hungarian, Russian

Education:

M.D., Semmelweis Medical University, Budapest, 1988
M.Sc., Cellular and Molecular Biology, Cancer Research Institute of Laval University, Quebec Canada 1992
B.Sc., Verseghy Gimn?zium, Szolnok Hungary 1982

Residency:

Semmelweis University , Budapest , 1988-1990
Internal Medicine, Mayo Clinic , Rochester MN 1996-1999

Fellowships:

Gastroenterology and Hepatology, Mayo Clinic , Rochester MN 1999-2003

Board Certifications:

American Board of Internal Medicine, 2010
American Board of Internal Medicine, Gastroenterology and Hepatology, 2014
American Board of Internal Medicine, Transplant Hepatology, 2008

Professional Memberships:

American Association for the Study of Liver Disease
American College of Physicians
American Gastroenterlogical Association
American Liver Foundation
American Society for Clinical Investigation

Select Honors and Awards:

Associate Editor, American Journal of Physiology, Gastrointestinal and Liver Physiology, 2015

Elected to the American Society for Clinical Investigation, 2014

Boris Ruebner and John Rosenquist Excellence in Teaching Award, UC Davis, GI and Hepatology, 2014

Richard C. Woodard Award, UC Davis Mentor, 2014

Internal Medicine-Pathology-Surgery Research Award, UC Davis, 2012

University of California, Cancer Research Coordinating Committee Award, 2006

Select Recent Publications:

Torok NJ: Update on Alcoholic Hepatitis. Biomolecules,  2015 Nov 2;5(4):2978-86.

Bettaieb A, Jiang JX, Sasaki Y, Chao TI, Kiss Z, Chen X, Tian J, Katsuyama M, Yabe-Nishimura C, Xi Y, Szyndralewiez C, Schröder K, Shah A, Brandes RP, Haj FG and Török NJ: “Hepatocyte NADPH Oxidase 4 Regulates Stress Signaling, Fibrosis, and Insulin Sensitivity during Development of Steatohepatitis in Mice”, Gastroenterology, 2015;Aug;149(2):468-480.

Torok NJ, JA. Dranoff, D. Schuppan and SL. Friedman: “Strategies and Endpoints of Antifibrotic Drug Trials” Hepatology, 2015;Aug;62(2):627-34.

Jiang JX, Torok NJ: ” MLK3 as a regulator of disease progression in NASH”. Liver Int. 2014 Apr 1.

Jiang XJ, Chen, X, Fukada, H, Serizawa, N, Devaraj, S, and Török, NJ:  Advanced glycation end products induce fibrogenic activity in NASH by modulating the TNF? converting enzyme activity in mice. Hepatology, 2013, Oct;58(4):1339-48.

To see if Natalie J. Torok is accepting new patients, or for assistance finding a UC Davis doctor, please call 800-2-UCDAVIS (800-282-3284).