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UC Davis Comprehensive Cancer Center

Mark J. Mannis, M.D. View profile as PDF

Mark J. Mannis

Clinical Interests

Dr. Mannis, professor and chair of the UC Davis Health System Eye Center, specializes in corneal transplantation and external diseases of the eye.

Research/Academic Interests

Dr. Mannis has authored over 125 publications and five books on topics relating to corneal surgery and disease. His research has included development of experimental antimicrobial agents and growth factors that affect the corneal wound healing rate, skin diseases that affect the eye, and outcomes of corneal transplants and artificial corneas.



Chair of Ophthalmology




Cornea and External Disease, Refractive Surgery and Uveitis

Center/Program Affiliation:


Laser Vision Correction Services - Department of Ophthalmology and Vision Science
Ophthalmology Clinic
77 Cadillac Dr.
Sacramento, CA 95825
Driving Directions
Phone: 916-734-6650

Lawrence J. Ellison Ambulatory Care Center
Ophthalmology Clinic-Eye Center
4860 Y St., Suite 2400
Sacramento, CA 95817
Driving Directions
Phone: 916-734-6602

Additional Phone:

Physician Referrals: 800-4-UCDAVIS (800-482-3284)

Other Languages:

German, Hebrew, Portuguese, Spanish


M.D., University of Florida College of Medicine, Gainesville, Florida, 1975
B.A., Brandeis University, Waltham, Massachusetts, 1968


University of Vermont, Burlington, Vermont


Washington University, St. Louis, Missouri


University of Iowa, Iowa City, Iowa

Board Certifications:

American Board of Ophthalmology, 1980

Professional Memberships:

American Academy of Ophthalmology
American Association of Tissue Banks
American College of Surgeons
American Medical Association
American Ophthalmological Society
Association for Research in Vision and Ophthalmology
Association of American Medical Colleges
Association of University Professors of Ophthalmology
California Association of Ophthalmology
California Medical Association

Select Recent Publications:

Simultaneous surgery for corneal edema and aphakia: DSEK and placement of a retropupillary iris claw lens. Vélez F M, Mannis MJ, Izquierdo L Jr, Sánchez JG, Velásquez LF, Rojas S. Cornea. 2014 Feb;33(2):197-200. doi: 10.1097/ICO.0b013e3182a9dffb.

Ocular rosacea: common and commonly missed.Vieira AC, Mannis MJ.J Am Acad Dermatol. 2013 Dec;69(6 Suppl 1):S36-41. doi: 10.1016/j.jaad.2013.04.042. Review.

Donor age and factors related to endothelial cell loss 10 years after penetrating keratoplasty: Specular Microscopy Ancillary Study. Writing Committee for the Cornea Donor Study Research Group, Lass JH, Benetz BA, Gal RL, Kollman C, Raghinaru D, Dontchev M, Mannis MJ, Holland EJ, Chow C, McCoy K, Price FW Jr, Sugar A, Verdier DD, Beck RW. Ophthalmology. 2013 Dec;120(12):2428-35. doi: 10.1016/j.ophtha.2013.08.044.

The effect of donor age on penetrating keratoplasty for endothelial disease: graft survival after 10 years in the Cornea Donor Study. Writing Committee for the Cornea Donor Study Research Group, Mannis MJ, Holland EJ, Gal RL, Dontchev M, Kollman C, Raghinaru D, Dunn SP, Schultze RL, Verdier DD, Lass JH, Raber IM, Sugar J, Gorovoy MS, Sugar A, Stulting RD, Montoya MM, Penta JG, Benetz BA, Beck RW.Ophthalmology. 2013 Dec;120(12):2419-27. doi: 10.1016/j.ophtha.2013.08.026.

Evaluation of microbial flora in eyes with a Boston type 1 Keratoprosthesis. Lee SH, Mannis MJ, Shapiro B, Li JY, Polage C, Smith W. Cornea. 2013 Dec;32(12):1537-9. doi: 10.1097/ICO.0b013e3182a81992.

Lessons in corneal structure and mechanics to guide the corneal surgeon. Jester JV, Murphy CJ, Winkler M, Bergmanson JP, Brown D, Steinert RF, Mannis MJ. Ophthalmology. 2013 Sep;120(9):1715-7. doi: 10.1016/j.ophtha.2013.07.004. No abstract available. Erratum in: Ophthalmology. 2013 Dec;120(12):2448. 

Eye banking and corneal transplantation communicable adverse incidents: current status and project NOTIFY. Dubord PJ, Evans GD, Macsai MS, Mannis MJ, Glasser DB, Strong DM, Noël L, Fehily D. Cornea. 2013 Aug;32(8):1155-66. doi: 10.1097/ICO.0b013e31828f9d64. Review.

Standard terminology and labeling of ocular tissue for transplantation. Armitage WJ, Ashford P, Crow B, Dahl P, DeMatteo J, Distler P, Gopinathan U, Madden PW, Mannis MJ, Moffatt SL, Ponzin D, Tan D. Cornea. 2013 Jun;32(6):725-8. doi: 10.1097/ICO.0b013e3182873405.

To see if Mark J. Mannis is accepting new patients, or for assistance finding a UC Davis doctor, please call 800-2-UCDAVIS (800-282-3284).