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UC Davis Comprehensive Cancer Center

Fu-Tong Liu, M.D., Ph.D. View profile as PDF

Fu-Tong  Liu

Clinical Interests

Fu-Tong Liu specializes in general dermatology with a particular interest in inflammatory skin disorders, including atopic dermatitis, psoriasis, and autoimmune skin diseases, as well as mast cell diseases, such as urticaria and mastocytosis. 


Research/Academic Interests

As an allergy and immunology researcher, he is a pioneer and leading investigator in the study of a family of proteins called galectins.

His research is focused on their functions in inflammation and immunity, as well as cancer progression and adiposity.

Title:

Distinguished Professor Emeritus and Chair Emeritus

Specialty:

Department:

Division:

Dermatology

Center/Program Affiliation:

Address/Phone:

Cannery Building
Dermatology
3301 C St., Suite 1300-1400
Sacramento, CA 95816
Driving Directions
Phone: 916-734-6111

Additional Phone:

Physician Referrals: 800-4-UCDAVIS (800-482-3284)

Other Languages:

Chinese (Mandarin)

Education:

M.D., University of Miami School of Medicine, Miami FL 1987
Ph.D., Organic Chemistry, University of Chicago, Chicago IL 1975
B.S., National Taiwan University, Taipei, Taiwan, 1970

Residency:

UC San Diego, San Diego CA 1990-1993

Board Certifications:

American Board of Dermatology, 1993

Professional Memberships:

American Academy of Dermatology
American Association for the Advancement of Science
American Association of Immunologists
American Chemical Society
American Society for Clinical Investigation
American Society for Investigative Pathology
Association of American Physicians
Society of Investigative Dermatology

Select Honors and Awards:

First KIA Laureate, the 28th Khwarizmi International Award, 2015

Fellow, American Association for the Advancement of Science, 2013

Academician, Academia Sinica, Taiwan, 2012

Lu Yau-Chin Memorial Lectureship, Taiwanese Dermatology Society, 2006

Joan Oettinger Memorial Award (Cancer and Pulmonary Research), UC Davis, 2005

Select Recent Publications:

Chen, H.-L., Chiang, P.-C., Lo, C.H., Lo, Y.H., Daniel K. Hsu, D.K., Chen, H.Y., Liu, F.-T. Galectin-7 regulates keratinocyte proliferation and differentiation through  JNK-miR-203-p63 signaling. J Invest Dermatol, 2016;136:182-91.

Wang, S.-F., Tsao, C.-H., Lin, Y.-T., Hsu, D.K., Chiang, M.-L., Lo, C.-H., Chien, F.-C., Chen, P., Chen, Y.-M., Chen, H.-Y., Liu, F.-T. Galectin-3 promotes HIV-1 budding via association with Alix and Gag p6. Glycobiol, 2014;24:1022-35.

Fermin-Lee, A, Chen, H.-Y., Wan, L., Wu, S.-Y, Yu, J.-S., Huang, A.C.,  Miaw, S.-C.,Hsu, D.K., Wu-Hsieh, B.A., and Liu, F.-T. Galectin-3 modulates Th17 responses by regulating dendritic cell cytokines. Am J Pathol, 2013;183:1209-22.

Choy, D.F., Hsu, D.K., Seshasayee, D., Fung, M.A., Modrusan, Z., Martin, F. Liu, F.T*., and Arron, J.R*. Comparative transcriptomic analyses of atopic dermatitis and psoriasis reveal shared neutrophilic inflammation. J Allergy Clin Immunol, 2012;130:1335-1343 (*co-corresponding author).

Liu, W., Hsu, D.K., Chen, H.-Y., Yang, R.-Y., Carraway KL 3rd, Isseroff RR, Liu, F.-T. Galectin-3 regulates intracellular trafficking of EGFR through Alix and promotes  keratinocyte migration. J Invest Dermatol. 2012;132:2828-37.

Yang, R.-Y., Yu, L., Graham, J., Hsu, D.K., Lloyd, K.C., Havel, P.J., and Liu, F.-T. Ablation of a galectin preferentially expressed in adipocytes increases lipolysis, reduces adiposity, and improves insulin sensitivity in mice. Proc Natl Acad Sci USA 2011;108:18696-701.

Saegusa, J., Hsu, D.K., Chen, H.-Y., Yu, L., Fermin, A., Fung, M.A., and Liu, F.-T. Galectin-3 is critical for the development of the allergic inflammatory response in a mouse model of atopic dermatitis. Am J Pathol, 2009;174:922-931.

Chen, H-Y., Fermin, A., Vardhana, S., Weng, I-C., Lo, K.F.R., Chang,E-Y., Maverakis, E., Yang, R.Y., Hsu, D.K., Dustin, M., and Liu, F.-T. Galectin-3 negatively regulates TCR-mediated CD4 T cell activation at the immunological synapse, Proc Natl Acad Sci USA, 2009;106:14496-14501.

Hsu, D.K., Chen, H.-Y., Yu, L., Chernyavsky, A.I., Grando, S.A., and Liu, F.-T. Endogenous galectin-3 is localized in membrane lipid rafts and regulates migration of dendritic cells. J Invest Dermatol, 2009;129:573-83.

Liu, F-T. and Rabinovich, G.A. Galectins as novel modulators of tumor progression. Nature Rev Cancer, 2005;5: 29-41.

To see if Fu-Tong Liu is accepting new patients, or for assistance finding a UC Davis doctor, please call 800-2-UCDAVIS (800-282-3284).