James Littlejohn, M.D., Ph.D.

James Eliot Littlejohn, M.D., Ph.D.

Specialties

Anesthesiology

Critical Care Medicine

Department

Anesthesiology

Title

  • Assistant Clinical Professor
To see if James Eliot Littlejohn is accepting new patients, or for assistance finding a UC Davis doctor, please call 800-2-UCDAVIS (800-282-3284).

Patient Support Services Building

4150 V St., Suite 1200
Sacramento, CA 95817
Driving Directions

Primary Phone:
916-734-5028

Additional Phone Numbers

Phone: 916-734-5031
Physician Referrals: 800-4-UCDAVIS (800-482-3284)

Research/Academic Interests

Dr. Littlejohn's research interests include: Acquired Coagulopathies and Hemorrhagic Shock.

Division

General Anesthesiology

Center/Program Affiliation

Trauma Program

Education

M.D., Ph.D., Texas A&M University College of Medicine, Bryan TX 2010

B.A., UC Berkeley, Berkeley CA 2002

Residency

Anesthesiology, New York Presbyterian Hospital - Weill Cornell Medical Center, New York NY 2011-2014

Fellowships

Critical Care Medicine, University of Pennsylvania Medical Center, Philadelphia PA 2014-2015

Board Certifications

American Board of Anesthesiology, 2015

American Board of Anesthesiology - Critical Care Medicine, 2015

Professional Memberships

American Medical Association

American Society of Anesthesiologists and California Society of Anesthesiologists

California Medical Association

Society of Critical Care Anesthesiology

Society of Critical Care Medicine

Honors and Awards

Joseph F. Atrusio Outstanding Resident Award, , Department of Anesthesia Weill Cornell Medical Center, 2014

American-Austria Foundation Fellow, Perioperative Bleeding Seminar, 2013

Weill-Cornell Department of Anesthesiology- Chief Resident, 2013

Select Recent Publications

Zhang L, Littlejohn JE, Cui Y, Cao X, Peddabonia C, Smythe WR. Characterization of bortezomib-adapted I-45 mesothelioma cells, Molecular Cancer. 2010 May 18; 9:110.

Cao, X., Littlejohn, J.E., Zhang, L., Martino, B., Rascoe, P., Rodarte, C., Smythe, WR. The Upregulation of Bcl-xL by Hepatocyte Growth Factor in Human Mesothelioma Cells Involves ETS Transcription Factors. Am J of Pathology, 2009;175(5):2201-2211.

Littlejohn, J.E., Cao, X., Miller, S.D., Ozvaran M.K., Jupiter, D., Zhang, L., Rodarte, C., Smythe W.R. BclxL antisense oligonucleotide and cisplatin combination therapy extends survival in SCID mice with established mesothelioma xenografts. International J of Cancer, 2008;123(1): 202-8.

Bumbaca, D., Littlejohn, J.E., Nayakanti, H., Lucas, A.H., Rigden, D.J., Galperin, M.Y., Jedrzejas, M.J. Genome based identification and characterization of a putative mucin-binding protein from the surface of Streptococcus pneumoniae. Proteins-Structure Function and Bioinformatics, 2007;66 (3): 547-558.

Cao, X., Rodarte,C., Zhang,L., Morgan,C.D., Littlejohn, J., and Smythe,W.R. Bcl2/bcl-x(L) Inhibitor Engenders Apoptosis and Increases Chemosensitivity in Mesothelioma. Cancer Biology and Therapy, 2007;6:246-252.

Nukui, M., Mello, L.V., Littlejohn, J.E., Setlow, B., Setlow, P., Kim, K., Leighton, T., Jedrzejas, M.J. Structure and molecular mechanism of Bacillus anthrasis cofactor-independent phosphoglycerate mutase: A crucial enzyme for spores and growing cells of Bacillus species. Biophysical Journal, 2007;92 (3): 977-988.

Rigden, D.J., Littlejohn, J.E., Joshi, H.V., de Groot, B.L., Jedrzejas, M.J. Alternate Structural Conformations of Streptococcus pneumoniae Hyaluronan Lyase: Insights into the Enzyme Flexibility and Underlying Molecular Mechanism of Action. J of Molecular Biology, 2006;358 (4): 1165-1178.

Bumbaca, D., Littlejohn, J.E., Nayakanti, H., Rigden, D.J., Galperin, M.Y., Jedrzejas, M.J. Sequence analysis and characterization of a novel fibronectin-binding repeat domain from the surface of Streptococcus pneumoniae. OMICS Winter, 2004;8(4):341-56.

Kolberg, J., Aase, A., Rodal, G., Littlejohn, J.E., Jedrzejas, M.J. Epitope mapping of pneumococcal surface protein A of strain Rx1 using monoclonal antibodies and molecular structure modeling. FEMS Immunology Medical Microbiology, 2003;39(3):265-73.

Rigden, D.J., Littlejohn, J.E., Henderson, K., Jedrzejas, M.J. Structures of phosphate and trivanadate complexes of Bacillus stearothermophilus phosphatase PhoE: structural and functional analysis in the cofactordependant phosphoglycerate mutase superfamily. J of Molecular Biology, 2003;325(3):411-20.