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Research at UC Davis Health System

Research at UC Davis Health System

News releases

April 2014arrow

SSRI use during pregnancy is associated with risk of autism, developmental delays in male children

April 14, 2014

Prenatal exposure to selective serotonin reuptake inhibitors (SSRIs), medications frequently prescribed to treat depression, anxiety and other mental-health disorders, is associated with a higher incidence of autism spectrum disorder (ASD) and developmental delays (DD) in male children, a study of nearly 1,000 mother-child pairs has found.

The vast majority of injuries and illnesses in agriculture are not counted

April 8, 2014

Federal agencies responsible for tracking workplace hazards fail to report 77 percent of the injuries and illnesses of U.S. agricultural workers and farmers, new research from UC Davis has found. [en español]

UC Davis researchers discover how high blood pressure damages the heart

April 7, 2014

A multidisciplinary research team at UC Davis has found a key biological trigger — a protein known as nitric oxide synthase, or NOS — that makes the heart beat stronger in response to higher blood pressure, along with a way to turn that trigger off when it becomes overactive.

UC Davis clinical trials -- helping revolutionize hepatitis C treatment

April 3, 2014

Jesse De La Cruz didn’t have any hepatitis C symptoms for nearly 15 years. Physicians say that’s fairly typical of an illness also known as “the silent killer.”

New test makes Parkinson's-like disorder of middle age detectable in young adulthood

April 2, 2014

The very earliest signs of a debilitating neurodegenerative disorder, in which physical symptoms are not apparent until the fifth decade of life, are detectable in individuals as young as 30 years old using a new, sophisticated type of neuroimaging, researchers at UC Davis, the University of Illinois and UCLA have found.

New technique quickly identifies molecular makeup of breast tumor cells

April 1, 2014

A new technology can simultaneously detect as many as 100 clinically important protein molecules in breast tumor cells – a quantum advance over conventional methods that can pinpoint only two to four at the same time. The advantages of the new methodology, called multiplexed ion beam imaging (MIBI), is described by a team of scientists at UC Davis and San Francisco and at Stanford, Genentec in the March 23 advance online publication of the journal Nature Medicine.

March 2014arrow

Time, trust and transparency keys to minority biospecimen collection

March 26, 2014

Blood and tumor specimen collection from cancer patients is critical to research into new, more personally targeted therapies. But biospecimen collection among diverse populations lags far behind that of whites. [Chinese, Vietnamese and Spanish]

UC Davis physician featured in national health equity project

March 24, 2014

UC Davis professor Christopher Bowlus of the Division of Gastroenterology and Hepatology, and his liver cancer disparity research, are featured on the Health Equity Research Snapshot of the Association of American Medical Colleges (AAMC).

Nine-year effort concludes to fund breast cancer endowment at UC Davis

March 21, 2014

After nine years and countless fund-raising events, the Placer Breast Cancer Endowment on Thursday reached its goal of $1.5 million for breast cancer research at UC Davis Comprehensive Cancer Center.

Stem cell findings may offer answers for some bladder defects and disease

March 21, 2014

For the first time, scientists have succeeded in coaxing laboratory cultures of human stem cells to develop into the specialized, unique cells needed to repair a patient’s defective or diseased bladder.

Potential lung cancer vaccine shows renewed promise

March 20, 2014

Researchers at UC Davis have found that the investigational cancer vaccine tecemotide, when administered with the chemotherapeutic cisplatin, boosted immune response and reduced the number of tumors in mice with lung cancer. The study also found that radiation treatments did not significantly impair the immune response. The paper was published on March 10 in the journal Cancer Immunology Research, an American Association for Cancer Research (AACR) publication.

UC Davis faculty drive efforts to improve CT safety

March 19, 2014

UC Davis clinicians and physicists have recommended new strategies to make computed tomography (CT) safer, including adoption of a new metric for dose measurement, ways to manage exposure protocols that differ by CT brand and specific approaches to reduce exposure during needle biopsies. The recommendations are detailed in papers published in the March issue of the Journal of the American College of Radiology (JACR).

Minority clinical trials participation and analysis still lag 20 years after federal mandate

March 18, 2014

Twenty years after Congress mandated that research funded by the National Institutes of Health include minorities, less than 5 percent of trials participants are non-white, and less than 2 percent of clinical cancer research studies focus on non-white ethnic or racial groups, UC Davis researchers have found. [Chinese, Spanish, Korean, Vietnamese]

Joint cancer center study finds barriers to minority clinical trial participation

March 18, 2014

A new study involving researchers from UC Davis and four other National Cancer Institute-designated cancer centers reveals important barriers that limit minority group participation in cancer clinical trials, findings that will be used to refine and launch more effective strategies to assure that more minorities benefit from clinical trials.

Statewide public cord blood collection program begins

March 17, 2014

Mothers of newborns can now donate their babies’ umbilical cord blood at UC Davis Medical Center and other hospitals throughout the state as part of California’s first comprehensive public system of collecting cord blood for lifesaving transplantations and medical research. [en español]

Electronic health records can be used to predict sepsis risk and mortality

March 14, 2014

UC Davis researchers have found that routine information — blood pressure, respiratory rate, temperature and white blood cell count — from the electronic health records (EHRs) of hospitalized patients can be used to predict the early stages of sepsis, a leading cause of death and hospitalization in the U.S. They also determined that just three measures — lactate level, blood pressure and respiratory rate — can pinpoint the likelihood that a patient will die from the disease.

UC Davis nursing school hopes to improve care for cancer patients with social network

March 14, 2014

Several chemotherapy patients at the UC Davis Comprehensive Cancer Center will be invited to use tablets with a unique social networking tool as part of their treatment plan.

Microbes in space

March 12, 2014

Microbes collected from Northern California and throughout the nation will soon blast into orbit for research and a microgravity growth competition on the International Space Station (ISS). This citizen science project, known as Project MERCCURI, is led in part by UC Davis microbiologists, who are investigating how microbes from different places on Earth compare to each other and to those found on the International Space Station.

UC Davis MIND Institute joins ranks of elite U.S. neurodevelopmental centers

March 11, 2014

The UC Davis MIND Institute has been named an Intellectual and Developmental Disabilities Research Center (IDDRC), through a prestigious grant from the Eunice Kennedy Shriver National Institute of Child Health and Human Development of the National Institutes of Health — a distinction held by only a handful of neurodevelopmental centers nationwide committed to the diagnosis, prevention, treatment and amelioration of developmental disorders such as autism, fragile X syndrome and Down syndrome.

UC Davis researchers one step closer to ovarian cancer marker

March 10, 2014

The hunt is on to find biomarkers that detect cancer, but it’s a challenging process. Early successes often are followed by heartbreaking failures.

Bone turnover markers predict prostate cancer outcomes

March 7, 2014

Biomarkers for bone formation and resorption predict outcomes for men with castration-resistant prostate cancer, a team of researchers from UC Davis and their collaborators have found.

Atypical development in the siblings of children with autism is detectable at 12 months

March 5, 2014

Atypical development can be detected as early as 12 months of age among the siblings of children with autism spectrum disorder, a study published by researchers with the UC Davis MIND Institute and UCLA has found.

February 2014arrow

UC Davis tests new smartphone app to help patients with mental illness

February 28, 2014

Sacramento-area youth in the early stages of serious mental illness can receive a new smartphone app that helps them detect early warning signs of psychosis, through a one-year, $588,000 grant to the UC Davis Early Diagnosis and Preventive Treatment (EDAPT) Clinic from the Robert Wood Johnson Foundation, to study whether harnessing mobile technology improves patient care.

Sloan Fellowship for "designer enzymes"

February 18, 2014

Justin Siegel, a biochemist at the University of California, Davis, who uses computers to develop new "designer enzymes" with properties not found in nature, has been awarded a prestigious Sloan Research Fellowship to support his work.

In-hospital formula use deters breastfeeding

February 14, 2014

When mothers feed their newborns formula in the hospital, they are less likely to fully breastfeed their babies in the second month of life and more likely to quit breastfeeding early, even if they had hoped to breastfeed longer, UC Davis researchers have found. [en español or 中文 Chinese

IPHI's Helen Wu receives prestigious research award from Robert Wood Johnson Foundation

February 6, 2014

Helen Wu, a research and policy scientist in the UC Davis Institute for Population Health Improvement (IPHI), has been selected to receive a Robert Wood Johnson Foundation Mentored Research Scientist Development Award under its Public Health Services and Systems Research Program.

Tighter economic regulation is needed to reverse obesity epidemic

February 2, 2014

Governments could slow — and even reverse — the growing epidemic of obesity by taking measures to counter fast food consumption, according to a study published today in the Bulletin of the World Health Organization.

January 2014arrow

Bruce Hammock receives 2014 Brodie Award

January 23, 2014

Bruce D. Hammock, UC Davis Distinguished Professor of Entomology, has received the 2014 Bernard B. Brodie Award from The American Society for Pharmacology and Experimental Therapeutics (ASPET).

UC Davis recognized as a research powerhouse

January 15, 2014

UC Davis placed among the nation’s leading institutions of higher education that conduct research funded by the National Institutes of Health (NIH) in 2013, according to data collected and tabulated by the Blue Ridge Institute for Medical Research, a North Carolina nonprofit organization that uses the NIH’s Research Portfolio Online Reporting Tools for its annual rankings.

Complementary medicine in wide use to treat children with autism, developmental delay

January 11, 2014

In a study of the range of treatments being employed for young children with autism and other developmental delays, UC Davis MIND Institute researchers have found that families often use complementary and alternative medicine (CAM) treatments and that the most frequent users of both conventional and complementary approaches are those with higher levels of parental education and income. [en español]

Katherine Rauen receives Presidential Early Career Award for Scientists and Engineers

January 10, 2014

Katherine A. Rauen, professor in the Department of Pediatrics and a physician-scientist affiliated with the UC Davis MIND Institute and UC Davis Children’s Hospital, has received a 2013 Presidential Early Career Award for Scientists and Engineers, the highest honor bestowed by the United States government on science and engineering professionals in the early stages of their research careers.

Men do not seek obesity surgery as soon as they should

January 6, 2014

Even though obesity affects women and men equally, a UC Davis study shows that obese women are four times more likely than obese men to seek weight-loss surgery. When they do see a bariatric surgeon, male patients tend to be older, more obese and sicker than women.

December 2013arrow

New MRI technique illuminates the wrist in motion

December 31, 2013

UC Davis radiologists, medical physicists and orthopaedic surgeons have found a way to create "movies" of the wrist in motion using a series of brief magnetic resonance imaging scans. Called "Active MRI," the technique could be useful in diagnosing subtle changes in physiology that indicate the onset of conditions such as wrist instability.

High good and low bad cholesterol levels are healthy for the brain, too

December 30, 2013

High levels of “good” cholesterol and low levels of “bad” cholesterol are correlated with lower levels of the amyloid plaque deposition in the brain that is a hallmark of Alzheimer’s disease, in a pattern that mirrors the relationship between good and bad cholesterol in cardiovascular disease, UC Davis researchers have found. [en español]

Detecting gastric cancer early -- it's in the sugars

December 20, 2013

Gastric cancer kills more than 700,000 people each year, mostly in Latin America, Asia and Eastern Europe. Though the disease is quite treatable when caught early, symptoms are indistinct and late detection leads to high mortality. The five-year survival rate in the United States is 26.9 percent.

Survival rates have not improved for metastatic prostate cancer

December 18, 2013

Since the prostate specific antigen (PSA) test was introduced in the late 1980s, prostate cancer mortality has dropped by more than 40 percent. However, there has been tremendous controversy over whether the PSA test has caused that decline.  In a newly published study, UC Davis researchers suggest that PSA screening likely plays an important role. [en español]   

MIND Institute research named a Top 10 Scientific Advance for 2013 by Autism Speaks

December 18, 2013

A study by UC Davis MIND Institute researchers has been named one of the Top 10 Scientific Advances of 2013 by Autism Speaks, the international science and advocacy organization.

The danger of sending patients home too soon after thyroid surgery

December 17, 2013

Removal of the thyroid gland is considered by most surgeons to be safe, which is why patients are often discharged from the hospital on the same day as the procedure. A new international, multicenter study published in the current issue of Surgery has found that some of these patients should be monitored in the hospital overnight for potentially deadly bleeding known as a post-surgical hematoma.

Pilot study finds ways to better screen and recover guns from domestic violence offenders

December 13, 2013

More intensive screening to identify firearm owners among individuals who are subject to domestic violence restraining orders, and streamlining processes to recover guns at the time those restraining orders are served could help enforce existing laws that prohibit these offenders from having firearms and using them to harm others, a pilot study conducted by violence prevention experts at the University of Californa, Davis, and the Johns Hopkins Bloomberg School of Public Health has found. [en español]

Stem cell agency funds UC Davis tissue-engineering research

December 12, 2013

Led by a renowned throat surgeon and a highly regarded stem cell researcher, a UC Davis team has received a $4.4 million grant from the California Institute for Regenerative Medicine (CIRM) to develop a stem cell-derived airway transplant to cure a difficult, life-threatening problem known as severe airway stenosis.

Hybrid clotting factor means fewer injections, better disease control for hemophilia patients

December 12, 2013

A Phase III clinical trial led by UC Davis researchers has confirmed that a new coagulation factor (rFIXFc) dramatically reduces the number of injections needed to maintain effective clotting for hemophilia B patients.

Better guidelines, coordination needed for prostate cancer specialists

December 9, 2013

With a deluge of promising new drug treatments for advanced prostate cancer on the market, a new model of care is needed that emphasizes collaboration between urologists and medical oncologists, according to UC Davis prostate cancer experts. [en español]

Paul Knoepfler receives National Advocacy Award at World Stem Cell Summit

December 6, 2013

Paul Knoepfler, associate professor of cell biology and human anatomy at UC Davis School of Medicine, was honored this week at the World Stem Cell Summit in San Diego for his stem cell advocacy and awareness efforts.

November 2013arrow

National study finds donor age not a factor in most corneal transplants

November 26, 2013

Ten years after a transplant, a cornea from a 71-year-old donor is likely to remain as healthy as a cornea from a donor half that age, and corneas from donors over 71 perform slightly less well but still remain healthy for most transplant recipients, according to a study funded by the National Eye Institute (NEI) and led by the UC Davis Health System Eye Center and the University of Cincinnati Eye Institute. [en español]

Telemedicine reduces pediatric medication errors in rural emergency departments

November 25, 2013

A new study from researchers at UC Davis has shown that telemedicine consultations from pediatric specialists reduced the number of drug errors in eight rural emergency departments. Published today in the journal Pediatrics, the study is the latest in research from UC Davis which demonstrates that telemedicine consultations can improve quality of care in rural settings. [中文 Chinese] or [en español]

Health insurance increases preventive care but not risky behaviors

November 22, 2013

People with health insurance are more likely to use preventive services such as flu shots and health screenings to reduce their risk of serious illness, but they are no more likely than people without health insurance to engage in risky health behaviors such as smoking or gaining weight, researchers at UC Davis and University of Rochester have found. [en español]

UC Davis Children's Hospital offers access to pediatric subspecialty care for rural newborns with PEANUT Program

November 13, 2013

UC Davis Children’s Hospital has been awarded a three-year, approximately $750,000 grant from the U.S. Department of Health and Human Services Office for the Advancement of Telehealth - Health Resources and Services Administration (OAT-HRSA) to expand its services for infants through the new Pediatric Emergency Assistance to Newborns Using Telehealth (PEANUT) Program.

Children who have autism far more likely to have tummy troubles

November 6, 2013

Children with autism experience gastrointestinal (GI) upsets such as constipation, diarrhea and sensitivity to foods six-to-eight times more often than do children who are developing typically, and those symptoms are related to behavioral problems, including social withdrawal, irritability and repetitive behaviors, a new study by researchers at the UC Davis MIND Institute has found. [en español] [中文 Chinese]

Interactive computer program helps patients talk with their physician about depression

November 5, 2013

Patients who used an interactive computer program about depression while waiting to see their primary-care doctor were nearly twice as likely to ask about the condition and significantly more likely to receive a recommendation for antidepressant drugs or a mental-health referral from their physician, according to a new study by researchers at UC Davis.

Solving the pediatric obesity problem in rural communities

November 4, 2013

Using telemedicine to unite clinicians and provide health education for them — and by extension, their patients — is an effective way to manage childhood obesity in remote areas. For these communities, which often have limited access to pediatric subspecialists, having a HEALTH-COP can make all the difference. [中文 Chinese] or [en español]

New grant to advance career opportunities for young scientists

November 4, 2013

As part of a national effort to broaden scientific training opportunities for young scientists and engineers and better prepare them for a wide variety of careers, the National Institutes of Health has awarded UC Davis a five-year, $1.7 million grant to support the Frontiers of University Training to Unlock the Research Enterprise (FUTURE) program  ̶  a campuswide effort that will expand academic offerings, internships and other experiential learning in the biomedical sciences for graduate students and postdoctoral scholars.

October 2013arrow

UC Davis participates in leading-edge research on fibroid treatment

October 31, 2013

UC Davis Department of Obstetrics and Gynecology researchers are participating in a University of California-wide clinical trial to test the long-term efficacy of ablating uterine fibroids ― benign non-cancerous uterine tumors ― using high-frequency radio waves that heat, shrink and kill the fibroid tissues during minimally invasive laparoscopic surgery.

Institute of Medicine names two UC Davis professors as members

October 21, 2013

Two faculty members at the University of California, Davis, have been elected to the Institute of Medicine, one of the nation’s highest honors in health and medicine.

All probiotics are not the same in protecting premature infants from common, life-threatening illness

October 17, 2013

Treating premature infants with probiotics, the dietary supplements containing live bacteria that many adults take to help maintain their natural intestinal balance, may be effective for preventing a common and life-threatening bowel disease among premature infants, researchers at UC Davis Children’s Hospital have found. [en español]

MIND Institute researcher partners to speed development of treatments for autism

October 15, 2013

Jacqueline Crawley, the Robert E. Chason Endowed Chair in Translational Research in the Department of Psychiatry and Behavioral Sciences, will participate in the Preclinical Autism Consortium for Therapeutics (PACT), a new partnership sponsored by Autism Speaks to facilitate the discovery of effective treatments for individuals with autism spectrum disorder. Other collaborators in the initiative are at Boston Children's Hospital and at the Baylor College of Medicine in Houston.

UC Davis CAARE Center awarded grant to help sexually exploited youth

October 14, 2013

The Department of Justice’s Office of Justice Programs has awarded the UC Davis CAARE Center a two-year, $400,000 grant to provide assessment, group therapy, individual therapy and case management for underage youth and youth who are at risk of sexual exploitation.

Gunshot injuries in children more severe, deadly and costly than other childhood injuries, study finds

October 14, 2013

A research team led by Oregon Health & Science University (OHSU) and the University of California, Davis, reveals that childhood gunshot injuries, while uncommon, are more severe, require more major surgery, have greater mortality and higher per-patient costs than any other mechanism for childhood injury – particularly among adolescent males. The study is published online in the journal Pediatrics. [en español]

UC Davis study finds potential biomarker differentiating the inattentive and combined subtypes of ADHD

October 8, 2013

Using a common test of brain functioning, UC Davis researchers have found differences in the brains of adolescents with the inattentive and combined subtypes of attention-deficit/hyperactivity disorder (ADHD) and teens who do not have the condition, suggesting that the test may offer a potential biomarker for the types of the disorder. [中文 Chinese] or [en español]

MIND Institute to participate in international study of schizophrenia in 22q11.2 deletion syndrome

October 7, 2013

Researchers at the UC Davis MIND Institute will participate in an international consortium spanning four continents that will study the genetics of schizophrenia and other psychiatric disorders in chromosome 22q11.2 deletion syndrome through a four-year, $12 million grant from the National Institute of Mental Health to the International Consortium on Brain and Behavior in 22q11.2 Deletion Syndrome.

Cigarette alternatives may not be 'safe' tobacco

October 4, 2013

Cigarette alternatives, widely perceived to be safe, are often addictive and can be stepping stones to cigarette smoking, according to a scientific review published online in the journal Clinical Reviews in Allergy and Immunology.

Despite menu changes, calorie and sodium levels in chain restaurant entrées remain the same overall

October 1, 2013

Although a number of chain restaurants have announced healthy menu changes over the years, the overall calorie and sodium levels in main entrées offered by top U.S. chain restaurants assessed from 2010 to 2011 have remained the same, according to a study published today in the Journal of the Academy of Nutrition and Dietetics. [en español]

September 2013arrow

UC Davis researchers discover a biological link between diabetes and heart disease

September 29, 2013

UC Davis Health System researchers have identified for the first time a biological pathway that is activated when blood sugar levels are abnormally high and causes irregular heartbeats, a condition known as cardiac arrhythmia that is linked with heart failure and sudden cardiac death.

New center to translate innovations into products that improve heart, lung health

September 27, 2013

A consortium of the five University of California medical campuses at Davis, Irvine, Los Angeles, San Diego and San Francisco has been awarded a $12 million grant and designated as one of three Centers for Accelerated Innovations by the National Heart, Lung and Blood Institute (NHLBI). The award, among the first of its kind from NHLBI, recognizes the University of California’s potential to translate its leading-edge discoveries into innovative products that benefit patients.

Gun retailers strongly support expanded criteria for denying gun purchases, UC Davis survey finds

September 23, 2013

A scientific survey of gun dealers and pawnbrokers in 43 U.S. states has found nearly unanimous support for denying gun purchases based on prior convictions and for serious mental illness with a history of violence or alcohol or drug abuse – conditions that might have prevented Washington Navy Yard shooter Aaron Alexis from legally purchasing a firearm.

Breastfeeding fraught with early challenges for most first-time mothers

September 23, 2013

Breastfeeding problems are extremely common among first-time moms, often causing them to introduce formula or completely abandon breastfeeding within two months, report researchers at the University of California, Davis, and the Cincinnati Children’s Hospital Medical Center.

UC Davis researchers find how viral infection disrupts neural development in offspring, increasing risk of autism

September 19, 2013

Activating a mother’s immune system during her pregnancy disrupts the development of neural cells in the brain of her offspring and damages the cells' ability to transmit signals and communicate with one another, researchers with the Center for Neuroscience and Department of Neurology have found. The researchers said the finding suggests how maternal viral infection might increase the risk of having a child with autism spectrum disorder or schizophrenia.

UC Davis MIND Institute researcher receives grant to explore four neurodevelopmental disorders

September 19, 2013

Jacqueline N. Crawley, an internationally renowned behavioral neuroscientist, has received a five-year, nearly $3 million grant from the National Institutes of Health to understand the synaptic dysfunctions that limit how people with certain neurodevelopmental disorders form memories and learn. The research also will investigate the effectiveness of potential targeted therapies for the disorders: fragile X syndrome, Rett syndrome, Down syndrome and Angelman syndrome.

Study finds that a subset of children often considered to have autism may be misdiagnosed

September 17, 2013

Children with a genetic disorder called 22q11.2 deletion syndrome, who frequently are believed to also have autism, often may be misidentified because the social impairments associated with their developmental delay may mimic the features of autism, a study by researchers with the UC Davis MIND Institute suggests.

Novel vaccine approach to human cytomegalovirus found effective

September 17, 2013

An experimental vaccine against human cytomegalovirus (CMV) infection, which endangers the developing fetus, organ transplant recipients, patients with HIV and others who have a weakened immune system, was safe and more effective than previous vaccines developed to prevent infection by the ubiquitous virus.

UC Davis study applies timely cost-effectiveness analysis to state breast cancer screening program

September 16, 2013

When public health budgets are constrained, mammography screening should begin later and occur less frequently, a cost-effectiveness analysis for California’s Every Woman Counts (EWC) program concludes. [en español]

Oct. 23 seminar lays out strategies for building new med-tech companies

September 12, 2013

Brook Byers, a general partner at Kleiner, Perkins, Caufield and Byers, a venture capital firm that launched Google, Amazon, Genentech and several other industry-defining companies, will describe lessons learned from a decade of helping scientists and entrepreneurs build medically focused companies based on molecular diagnostics, biotech and informatics breakthroughs.

"Incidental findings" rare but significant events in pediatric CT scans

September 11, 2013

The largest study of computed tomographic (CT) scans taken in emergency departments across the country for children with head injuries describes the prevalence of “incidental findings” –  results that were not expected from the injury –  and categorizes them by urgency. The article, titled “Incidental findings in children with blunt head trauma evaluated with cranial CT scans,” was published in the August issue of Pediatrics, and provides a context for doctors in emergency departments who encounter these situations.

Brain circuitry loss may be a very early sign of cognitive decline in healthy elderly people

September 9, 2013

The degeneration of a small, wishbone-shaped structure deep inside the brain may provide the earliest clues to future cognitive decline, long before healthy older people exhibit clinical symptoms of memory loss or dementia, a study by researchers at the UC Davis Alzheimer's Disease Center has found.

UC Davis endowed chair for clinical cancer research established

September 4, 2013

Karen Kelly, Associate Director for Clinical Research at the UC Davis Comprehensive Cancer Center, is the recipient of the university’s first endowed chair in Cancer Clinical Research.

Virtual reality and social training for autism study seeks participants

September 3, 2013

Using a virtual‐reality game, UC Davis researchers have begun to examine how children with high‐functioning autism learn in classroom settings, where social deficits can form obstacles to the engagement with teachers and classmates necessary for academic success. The study will examine their virtual classroom behavior and attention and compare it with that of children with attention-deficit/hyperactivity disorder (ADHD) and those with typical development.

August 2013arrow

Nobel laureate to explain the importance of the Higgs particle

August 29, 2013

Gerard ‘t Hooft, one of the international scientists whose Nobel Prize winning research contributed to the discovery of the Higgs particle, will speak in Sacramento on September 5 about how the particle was detected, what it means in terms of understanding the subatomic world and the future discoveries it will likely inspire.

Study identifies better blood glucose monitor for burn care

August 28, 2013

Glucose monitoring systems with an autocorrect feature that can detect red blood cells (hematocrit), vitamin C and other common interferents in burn patients’ blood are better for monitoring care, a pilot study conducted by UC Davis researchers at the School of Medicine and College of Engineering has found. The study was published in the Journal of Burn Care Research.

UC Davis team "spikes" stem cells to generate myelin

August 28, 2013

Stem cell technology has long offered the hope of regenerating tissue to repair broken or damaged neural tissue.

New strategy tests for dangerous stage of tuberculosis in Asia

August 20, 2013

More than 20,000 people in Pakistan are being tested for the potentially deadly stage of tuberculosis using a new strategy developed at UC Davis Health System to effectively detect the disease in children for the first time.

UC Davis researchers discover molecular target for the bacterial infection brucellosis

August 15, 2013

UC Davis scientists have uncovered a potential drug target for the development of an effective therapy against the debilitating, chronic form of the bacterial disease brucellosis, which primarily afflicts people in Mediterranean and Middle Eastern countries.

UC Davis researchers receive $2.5 million grant to study telepsychiatry

August 15, 2013

Researchers at UC Davis have received a five-year, $2.5 million grant to study whether viewing videotaped interviews with patients to assess them and guide their mental-health treatment is more cost-effective and better for patient outcomes and satisfaction than real-time telepsychiatric evaluation.

Targeting aggressive prostate cancer

August 14, 2013

A team of researchers from UC Davis, UC San Diego and other institutions has identified a key mechanism behind aggressive prostate cancer.

Trends in psoriasis and psoriatic arthritis treatments

August 14, 2013

Many patients with psoriasis and psoriatic arthritis are not benefiting from the expanding array of treatments now available to combat these serious autoimmune disorders, researchers led by a UC Davis dermatologist report in a new study published online today by JAMA Dermatology.

Expanded role of paramedics shows promise for closing California's health-care gaps

August 14, 2013

In a new report, the UC Davis Institute for Population Health Improvement (IPHI) recommends that the state launch pilot programs to test a new model of community-based health care that would expand the role of paramedics under certain circumstances.

International research team identifies top risk factors for children during influenza pandemics

August 13, 2013

An international team of pediatric specialists, representing the world’s five major pediatric emergency medicine research networks, has identified several crucial risk factors for alerting clinicians to children most susceptible to life-threatening infections from the H1N1 influenza (flu). It is the first study to detail which clinical factors at hospital arrival in children with influenza-like illness and H1N1 infection are associated with the progressive risk to either severe infection or death.

Telemedicine consultations significantly improve pediatric care in rural emergency rooms

August 8, 2013

Telemedicine consultations with pediatric critical-care medicine physicians significantly improve the quality of care for seriously ill and injured children treated in remote rural emergency rooms, where pediatricians and pediatric specialists are scarce, a study by researchers at UC Davis Children’s Hospital has found. [en español]

UC Davis "lab on a chip" measures heart disease risk

August 6, 2013

Using a special microchip that can perform laboratory functions, a team of cardiologists and biomedical engineers from UC Davis has identified cells linked with inflammation and varying degrees of heart disease.

Knoepfler to receive award for stem cell advocacy

August 6, 2013

Paul Knoepfler, associate professor of cell biology and human anatomy, will be honored in December by the Genetics Policy Institute (GPI) with one of its annual Stem Cell Action awards.

How a cancer drug unties knots in the chromosome that causes Angelman and Prader-Willi syndromes

August 5, 2013

UC Davis researchers have identified how and where in the genome a cancer chemotherapy agent acts on and ‘un-silences’ the epigenetically silenced gene that causes Angelman syndrome, a rare neurodevelopmental disorder characterized by severe intellectual disability, seizures, motor impairments, and laughing and smiling.

UC Davis researchers receive grant to study depression and suicide in older men

August 2, 2013

Researchers at UC Davis have received a three-year, $725,000 grant from the National Institute on Mental Health to develop new, creative approaches to decreasing the burden of late-life depression and the risk of suicide among older men.

July 2013arrow

Novel inhibitor of C-reactive protein holds promise as cardiovascular disease treatment

July 24, 2013

UC Davis scientists have developed a novel cardiovascular agent which, unlike currently available drugs for heart disease, does not target high blood cholesterol or high blood pressure.

A new weapon against stroke

July 23, 2013

One of regenerative medicine’s greatest goals is to develop new treatments for stroke. So far, stem cell research for the disease has focused on developing therapeutic neurons — the primary movers of electrical impulses in the brain — to repair tissue damaged when oxygen to the brain is limited by a blood clot or break in a vessel. New UC Davis research, however, shows that other cells may be better suited for the task. [ 中文 (Chinese)] [en español]

New herbal supplement helps slim and trim without side effects, studies show

July 23, 2013

Study participants who took a new herbal supplement, while also exercising and controlling their food intake, had greater success in losing weight and slimming down than did those who didn’t take the supplement, report researchers at the University of California, Davis, and in India.

UC Davis MIND Institute researchers seek participants for study on generalizing learning in autism

July 18, 2013

Researchers at the UC Davis MIND Institute are seeking adolescents to participate in a groundbreaking brain imaging study aimed at understanding one of the most critical aspects of autism spectrum disorders: how people with autism generalize things they learn to new contexts.

UC Davis Nursing doctoral candidate examines impact of privacy laws on researchers' abilities to share data

July 16, 2013

Betty Irene Moore School of Nursing at UC Davis Doctoral Candidate Katherine Kim and a team of researchers recommend the development of guidelines that protect patient preferences and privacy while allowing investigators to share data through electronic health records and other databases. The research, “Development of a Privacy and Security Policy Framework for a Multi-state Comparative Effectiveness Research Network,” is published today in Medical Care, a national public health journal.

Eye specialist to develop novel eye imaging technologies

July 15, 2013

UC Davis Health System’s Eye Center has received a $250,000 Career Development Award from Research to Prevent Blindness to support the research of Ala Moshiri, an assistant professor of ophthalmology and director of electrophysiology services at the Eye Center.

Excessive cerebrospinal fluid and enlarged brain size in infancy are potential biomarkers for autism

July 9, 2013

Children who were later diagnosed with autism spectrum disorder had excessive cerebrospinal fluid and enlarged brains in infancy, a study by a multidisciplinary team of researchers with the UC Davis MIND Institute has found, raising the possibility that those brain anomalies may serve as potential biomarkers for the early identification of the neurodevelopmental disorder. [en español or 中文 Chinese]

UC Davis MIND Institute researchers find exposure to prenatal maternal antibodies affects behavior, development in offspring

July 9, 2013

Researchers with the UC Davis MIND Institute have found that prenatal exposure to specific antibodies found only in mothers of children with autism leads to changes in the brain that adversely affect behavior and development. [en español]

UC Davis MIND Institute researchers identify specific fetal antigens attacked by maternal antibodies

July 9, 2013

UC Davis MIND Institute researchers have identified the specific antibodies that target fetal brain proteins in the blood of a subset of women whose children are diagnosed with autism. The finding is the first to pinpoint a specific risk factor for a significant subset of autism cases, as well as a biomarker for drug development and early diagnosis. The researchers have named autism related to these antibodies “Maternal Autoantibody-Related," or MAR autism. [en español] [中文 Chinese]

Are the 'U.S. News' medical school rankings for primary care education relevant?

July 8, 2013

The U.S. News & World Report graduate school rankings inspire discussion and marketing, but do they actually reflect quality differences between schools when it comes to medical education in primary care? Researchers at the UC Davis School of Medicine are believed to be the first to take on that question by analyzing the primary care rankings from 2009 through 2012, reconstructing scores and proposing alternative measurements.

Nearly half of sarcoma surgeries done by nonsurgical oncology specialists

July 8, 2013

Orthopedic oncologists and surgical oncologists, who have been trained in the complex procedures required to remove sarcomas located deep in the muscles and other soft tissues of the limbs, conducted only 52 percent of these operations at 85 academic medical centers during a three year period, according to an analysis of national data by UC Davis researchers that is published online today in the Journal of Surgical Oncology.

June 2013arrow

A second amyloid may play a role in Alzheimer's disease, UC Davis researchers find

June 27, 2013

A protein secreted with insulin travels through the bloodstream and accumulates in the brains of individuals with type 2 diabetes and dementia, in the same manner as the amyloid beta (Αβ) plaques that are associated with Alzheimer’s disease, a study by researchers with the UC Davis Alzheimer’s Disease Center has found. [en español or 中文 Chinese]

Aerial mosquito spraying study finds no immediate public health risks

June 27, 2013

In what researchers say is the first public health study of the aerial mosquito spraying method to prevent West Nile virus, a UC Davis study analyzed emergency department records from Sacramento area hospitals during and immediately after aerial sprayings in the summer of 2005. [en español]

Symptoms of Prader-Willi syndrome associated with interference in circadian, metabolic genes

June 25, 2013

Researchers with the UC Davis MIND Institute and Agilent Laboratories have found that Prader-Willi syndrome — a genetic disorder best known for causing an insatiable appetite that can lead to morbid obesity — is associated with the loss of non-coding RNAs, resulting in the dysregulation of circadian and metabolic genes, accelerated energy expenditure and metabolic differences during sleep.

Evolution of an outbreak: complications from contaminated steroid injections

June 19, 2013

A study of the patients who received injections of steroids contaminated with the fungus Exserohilum rostratum from the New England Compounding Center has found that some patients had fungal infections even though they did not experience a worsening of their symptoms and that magnetic resonance imaging (MRI) can help detect spinal infections, especially among those individuals who received injections from highly contaminated lots. The study, along with an editorial by UC Davis Assistant Professor of Medical Microbiology and Immunology George R. Thompson, appears in the June 19 issue of the Journal of the American Medical Association.

Reducing unnecessary and high-dose pediatric CT scans could cut associated cancers by 62 percent

June 10, 2013

A study examining trends in X-ray computed tomography (CT) use in children in the United States has found that reducing unnecessary scans and lowering the doses for the highest-dose scans could lower the overall lifetime risk of future imaging-related cancers by 62 percent. The research by a UC Davis Health System scientist is published online today in JAMA Pediatrics. It is accompanied by a journal editorial. [en español]

UC Davis a longtime leader in appropriate CT scanning in children

June 10, 2013

UC Davis has a long history of  research pertaining to appropriate CT scanning in children with trauma, and the risks to children of unnecessary CT scans. This work has been performed through its leadership in the Pediatric Emergency Care Applied Research Network (PECARN), the only federally funded pediatric emergency care research network in the U.S., co-founded by Nathan Kuppermann, chair of the UC Davis Department of Emergency Medicine and an internationally respected pediatric emergency medicine physician.

Researchers find diminished balance in those with poor vision

June 6, 2013

UC Davis Health System Eye Center research has found that visually impaired individuals and those with uncorrected refractive error — those who could benefit from glasses to achieve normal vision but don’t wear glasses — have a significantly greater risk of diminished balance with their eyes closed on a compliant, foam surface than individuals with normal vision.

Lack of awareness limits use of flexible career policies in academia

June 3, 2013

To attract and maintain a diverse, qualified academic workforce, institutions of higher education should have — and promote — policies to help balance career and family life, according to an article published by UC Davis researchers in the June 2013 issue of Academic Medicine.

May 2013arrow

School-located vaccination programs could reduce flu cases and deaths among children

May 31, 2013

Offering flu vaccines at elementary schools could expand vaccination rates and reduce costs, according to a new study reported in the scientific journal Vaccine by researchers from UC Davis Health System; the Monroe County, N.Y., Department of Public Health; University of Rochester Medical Center; and U.S. Centers for Disease Control and Prevention (CDC). [en español]

Father and son to present their respective cancer research at ASCO

May 29, 2013

What started as a dinner-table conversation between a teen and his father has become a bonafide cancer research study for Matthew Lara, a Davis High School sophomore and the son of UC Davis Comprehensive Cancer Center medical oncologist and researcher Primo (Lucky) Lara Jr.

Health differences explain most geographic variation in Medicare costs

May 28, 2013

Wide geographic variation in Medicare costs is largely explained by health differences across communities rather than inefficient care delivery, according to a study published online today in the SAGE journal Medical Care Research and Review.

UC Davis researchers receive grant to study neurodegenerative disease FXTAS

May 22, 2013

Researchers at the UC Davis MIND Institute and the UC Davis Center for Mind and Brain have received a five-year, $3 million grant from the National Institute of Mental Health to conduct the first long-range study of the mental and psychological decline that accompanies the age-related neurological disorder fragile X-associated tremor/ataxia syndrome, or FXTAS.

Past trauma, poor understanding of health-care services common among Sacramento Iraqi refugees

May 20, 2013

Past trauma and a lack of understanding of the U.S. health-care system are key factors affecting the mental and physical health of Iraqi refugees in Sacramento, according to a new report released by UC Davis’ Center for Reducing Health Disparities and Clinical and Translational Science Center, as well as Opening Doors Inc. and the Mesopotamia Organization (MESO) —  two community groups  that serve refugee populations.

Study identifies new approach to improving treatment for MS and other conditions

May 17, 2013

Working with lab mice models of multiple sclerosis (MS), UC Davis scientists have detected a novel molecular target for the design of drugs that could be safer and more effective than current FDA-approved medications against MS.

UC Davis Center for Reducing Health Disparities receives $1 million grant from Covered California

May 15, 2013

The UC Davis Center for Reducing Health Disparities has received a $1 million grant from Covered California, the state’s health insurance marketplace, to provide outreach and education to underserved populations about obtaining health insurance.

UC Davis receives awards to study new treatments for childhood diseases

May 13, 2013

Three researchers from the University of California, Davis, are among the scientists selected to receive Individual Biomedical Research Awards from The Hartwell Foundation this year. The awards recognize early-stage, innovative and cutting-edge biomedical research that has the potential to benefit children in the U.S. and beyond

Tailoring pulmonary rehabilitation could improve outcomes for women with COPD

May 10, 2013

—One of the most effective treatments for chronic obstructive pulmonary disease (COPD) — pulmonary rehabilitation — could potentially work even better if programs were designed based on gender, according to a UC Davis pulmonary physician.

UC Davis researchers identify mechanism for controlling calcium influx in cells

May 8, 2013

When brain cells are overwhelmed by an influx of too many calcium molecules, they shut down the channels through which these molecules enter the cells. Until now, the “stop” signal mechanism that cells use to control the molecular traffic was unknown. In the new issue of the journal Neuron, UC Davis Health System scientists report that they have identified the mechanism. Their findings are relevant to understanding the molecular causes of the disruption of brain functioning that occurs in stroke and other neurological disorders.

UC Davis radiation oncology chief leads development of new prostate cancer guideline

May 7, 2013

Based on a major effort co-led by UC Davis prostate cancer expert Richard Valicenti, the nation’s leading urological and radiation oncology organizations today announced a new guideline for radiation therapy after prostatectomy.

Ubiquitous engineered nanomaterials cause lung inflammation, study finds

May 6, 2013

A consortium of scientists from across the country has found that breathing ultrafine particles from a large family of materials that increasingly are found in a host of household and commercial products, from sunscreens to the ink in copy machines to super-strong but lightweight sporting equipment, can cause lung inflammation and damage.