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Research at UC Davis Health System

Research at UC Davis Health System

News releases

March 2015arrow

UC Davis receives $10 million grant to establish center to study schizophrenia

March 26, 2015

UC Davis will establish a prestigious, leading-edge center to advance innovative research into the origins of schizophrenia: A Silvio O. Conte Center for Basic or Translational Mental-Health Research, one of only 15 such centers in the United States.

Nation's first conference on career flexibility for biomedical faculty features insights from Howell

March 19, 2015

In what was the first-ever convening of its kind, medical school leaders from across the nation met in Boston last week to discuss how academic physicians and scientists can have thriving careers with better work-life flexibility in an era of austere academic budget cuts.

Firearm violence trends in the 21st century

March 19, 2015

While the overall death rate from firearm violence has remained unchanged for more than a decade, the patterns for suicide and homicide have changed dramatically, a UC Davis study on the epidemiology of gun violence from 2003 to 2012 has found. The study was published today in the Annual Review of Public Health.

Randi Hagerman receives International Sisley-Lejeune Foundation Award

March 18, 2015

Randi Hagerman, medical director of the UC Davis MIND Institute, has received the prestigious International Sisley-Jerome Lejeune Award 2014 from the Paris-based Jérôme Lejeune Foundation, for her groundbreaking work developing targeted treatments for individuals with fragile X syndrome, a leading cause of intellectual disability and the leading single-gene cause of autism spectrum disorder.  

Commentary says study affirms that varied factors contribute to cognitive decline throughout adulthood

March 16, 2015

A study published online today in JAMA Neurology that finds associations between reduced hippocampal volume (HVa) and being male, but not the gene APOE ɛ4, suggests that there are multiple factors contributing to cognitive decline throughout adulthood, according to an accompanying commentary by UC Davis Alzheimer's Disease Center Director Charles DeCarli.

UC Davis School of Medicine ranks among nation's best in primary care, research

March 10, 2015

U.S. News & World Report has ranked UC Davis School of Medicine among America's best medical schools for the quality of its educational programs in primary care and research. The news magazine's annual listing appeared today on the publication's website and will be published in its guidebook “Best Graduate Schools 2016.”

Lim to receive Kun-Po Soo Award from American Psychiatric Foundation

March 6, 2015

Russell Lim, director of Diversity Education and Training for the UC Davis Department of Psychiatry and Behavioral Sciences, has received the 2015 Kun-Po Soo Award from the American Psychiatric Foundation, for his contributions to understanding the importance of addressing culture in mental-health issues.

UC Davis scientists describe novel drug mechanism that fights brain cancer

March 3, 2015

Researchers at UC Davis have developed and characterized a molecule that interferes with the internal regulation of cancer cells, causing them to self-destruct. This novel mechanism was found to be effective against glioma cells – responsible for a usually fatal type of brain cancer – and could be applicable to other highly aggressive cancers.

February 2015arrow

Undocumented farmworkers use Medicaid half as often as documented farmworkers

February 23, 2015

Undocumented farmworkers are half as likely as those who are documented to use Medicaid, the federal health insurance program available to low-income individuals and families, according to a new study from UC Davis Health System.

Hispanics develop alcoholic liver disease at younger ages than Caucasians or African Americans

February 20, 2015

Hispanics tend to develop alcoholic liver disease (ALD) — a common cause of liver-disease deaths in the U.S. — between four and 12 years earlier than non-Hispanic Caucasians or African Americans, according to a UC Davis Health System study.

UC Davis researchers identify new compound that takes aim at neuropathic pain

February 10, 2015

A new compound discovered by a team of UC Davis investigators has potent actions against production of a chemical that is implicated in the development of chronic pain following a peripheral nerve injury in the spinal cord.

A simple information sheet can help women avoid pregnancy and acne medication-related birth defects

February 4, 2015

An information sheet for women being treated for severe acne improves understanding of contraceptive effectiveness and ways to avoid pregnancy and medication-induced birth defects, a study published today in JAMA Dermatology has found.

Nerve regeneration therapy has potential to prevent arrhythmias, sudden cardiac death after heart attack

February 2, 2015

A therapy currently under development for spinal cord injuries has been shown to stimulate nerve regeneration in the heart and provide resistance to arrhythmias following a heart attack, according to a new study published today in the journal Nature Communications.

UC Davis scientists awarded nearly $4 million for technology in vascular disease treatment and bone and cartilage repair

February 2, 2015

The California Institute for Regenerative Medicine (CIRM) has awarded a pair of $1.8 million grants to two UC Davis scientists to develop better tools for enabling physicians to assess the safety and efficacy of bioengineered tissues used to treat cardiovascular disease and bone and cartilage repair.

January 2015arrow

California breast density law slow to have an impact

January 28, 2015

Ten months after California legislators enacted a controversial law mandating that radiologists notify women if they have dense breast tissue, UC Davis researchers have found that half of primary care physicians are still unfamiliar with the law and many don’t feel comfortable answering breast density-related questions from patients.

Institute for Population Health Improvement recruits California-based labs for no-cost mapping services

January 21, 2015

The UC Davis Institute for Population Health Improvement (IPHI) is recruiting California-based labs to participate in the Laboratory Mapping Assistance Project (Lab MAP). Participating labs will receive free code mapping to convert proprietary order, result and observation codes to standard codes, namely the Logical Observation Identifiers Names and Codes (LOINC) and Systematized Nomenclature of Medicine — Clinical Terms (SNOMED CT®) terminologies.

Moon Chen's research featured in ASCO's 2015 cancer progress report

January 21, 2015

UC Davis professor Moon Chen’s research on the under-representation of minorities in clinical trials appears in the American Society in Clinical Oncology (ASCO)’s annual cancer progress report released Tuesday.

Trauma surgery moves outside of the OR, fills gaps across specialties

January 20, 2015

Historically known as heroes who put people back together after accidents, trauma surgeons today perform a broad array of surgical procedures, are involved in planning patient care and treat patients at hospital bedsides in addition to operating rooms, a UC Davis Health System study has found.

Treating non-healing bone fractures with stem cells

January 15, 2015

A new device that can rapidly concentrate and extract young cells from irrigation fluid used during orthopaedic surgery holds promise for improving the delivery of stem cell therapy in cases of non-healing fractures.

UC Davis nursing professor increases Spanish health-care knowledge and confidence in graduate students

January 12, 2015

A Betty Irene Moore School of Nursing at UC Davis faculty member received the Provost Hybrid Course Award for a course designed to educate clinical graduate students in Spanish health terminology.

Aubyn Stahmer, expert in translating autism research into community practice, joins UC Davis MIND Institute

January 8, 2015

Aubyn Stahmer, an expert in the translation of evidence-based autism research to community-based practice and delivery, has joined the UC Davis MIND Institute as an associate professor in the Department of Psychiatry and Behavioral Sciences.

Study identifies patients at higher risk for overdose and death from prescription painkillers

January 7, 2015

Patients started on prescription painkillers who have substance-use disorders or who frequently contact their doctors’ offices are at greater risk of having their medication doses increase early in therapy, also increasing their risk of opioid-related overdose or death, UC Davis Health System researchers have found.

December 2014arrow

New technique for bioengineering stem cells shows promise in HIV resistance

December 22, 2014

Using modified human stem cells, a team of UC Davis scientists has developed an improved gene therapy strategy that in animal models shows promise as a functional cure for the human immunodeficiency virus (HIV) that causes AIDS.  The achievement, which involves an improved technique to purify populations of HIV-resistant stem cells, opens the door for human clinical trials that were recently approved by the U.S. Food and Drug Administration.

Study funded on the clinical, financial effectiveness of telemedicine versus telephone consultations

December 16, 2014

The U.S. Department of Health and Human Services has awarded a $1,198,384 grant to UC Davis pediatrician James Marcin to investigate how telemedicine consultations in emergency departments impact clinical outcomes, including cost effectiveness, compared with telephone consultations. 

Too much, too little, just right

December 15, 2014

Scientists have long known the p53 protein suppresses tumors. However, a recent animal study by UC Davis researchers has uncovered a complicated relationship between p53 and another protein, Rbm38, highlighting how the body calibrates protein levels. Too much Rbm38 reduces p53 levels, increasing the risk of cancer. Too little Rbm38 allows p53 overexpression, causing premature aging. The study was published in the journal PNAS on Dec. 15. 

Preeclampsia during mother's pregnancy associated with greater autism risk

December 8, 2014

Children with autism spectrum disorder (ASD) were more than twice as likely to have been exposed in utero to preeclampsia, and the likelihood of an autism diagnosis was even greater if the mother experienced more severe disease, a large study by researchers with the UC Davis MIND Institute has found.

MIND Institute says "thank you" to hundreds of participants in its research

December 3, 2014

Hundreds of participants in UC Davis MIND Institute research and their families will head into the woods to “Explore the Great Outdoors” during its 12th Annual Thank You Party on Saturday, Dec. 6, from 1 to 4 p.m. The party is held to thank the children, adolescents, adults and their families who make the MIND Institute's groundbreaking research into autism and other neurodevelopmental conditions possible.

November 2014arrow

International study reveals the genetics of malaria-carrying mosquitoes

November 27, 2014

More than 100 scientists, including a team of UC Davis molecular biologists, have sequenced the genomes of 16 Anopheles mosquito species to help define the characteristics that make some of them uniquely capable of transmitting malaria parasites to humans.

'Tis the season to indulge in walnuts

November 13, 2014

Researchers at UC Davis and other institutions have found that diets rich in whole walnuts or walnut oil slowed prostate cancer growth in mice. In addition, both walnuts and walnut oil reduced cholesterol and increased insulin sensitivity.

National study provides insights into childhood head injuries

November 12, 2014

This week’s issue of the New England Journal of Medicine features an article that highlights an unprecedented analysis of the nation’s childhood head injuries.

UC Davis investigational medication used to resolve life-threatening seizures in children

November 12, 2014

In its first clinical application in pediatric patients, an investigational medication developed and manufactured at UC Davis has been found to effectively treat children with life-threatening and difficult-to-control epileptic seizures without side effects, according to a research report by scientists at UC Davis and Northwestern University.

Lung cancer screening for Medicare patients coming soon to UC Davis

November 10, 2014

UC Davis Medical Center is preparing to screen seniors on Medicare who meet the criteria for lung cancer screening using low-dose computed tomography (CT).

Immunotherapy for cancer toxic with obesity

November 3, 2014

Immunotherapy that can be effective against tumors in young, thin mice can be lethal to obese ones, a new study by UC Davis researchers has found. [en español]

October 2014arrow

UC Davis researchers examine risks, benefits of chemotherapy for early-stage breast cancer

October 31, 2014

Treatment for early stage breast cancer is highly effective, and for many women considering treatment choices, chemotherapy may add little to an already high long-term survival rate. Joy Melnikow, professor in the Department of Family and Community Medicine and Director of the Center for Healthcare Policy and Research at UC Davis, is working to define the potential long-term harms of chemotherapy for these patients, so they can be weighed against the potential benefits.

UC Davis MIND Institute researchers to establish new tests to evaluate cognitive growth in people with intellectual disability

October 30, 2014

Researchers with the UC Davis MIND Institute will develop and evaluate tests designed to measure and track changes in the cognitive functioning of people who typically are difficult to assess accurately: those with an intellectual disability, formerly termed mental retardation. The research will be funded through a new, five-year, $3.2 million grant from the National Institutes of Health (NIH).

Study on Western diet and role in GI cancer funded

October 28, 2014

The National Cancer Institute (NCI) has awarded a $2.7 million grant to UC Davis researchers to investigate how the so-called Western diet, which is high in fat and sugar, increases the risk of developing liver and gastrointestinal (GI) cancers. In addition, the researchers will study whether bifidobacteria, a common family of bacteria in the human gut, can be enriched to prevent cancer.

UC Davis researchers find promising new treatment approach for ischemic stroke

October 27, 2014

A team of UC Davis scientists has found that administering a small molecule – purmorphamine – in animal models after a stroke results in multiple protective effects, including reducing the size of the stroke, decreasing inflammation and increasing markers for nerve regeneration.

Anti-cancer drug found effective against common stem cell transplant complication

October 24, 2014

Researchers at UC Davis have found that the drug bortezomib effectively treats chronic graft-versus-host disease (GVHD), a common and debilitating side effect from allogeneic hematopoietic stem cell transplants.

Kravitz honored for outstanding research in health-care communication

October 24, 2014

The American Academy on Communication in Healthcare (AACH) has recognized Richard Kravitz, professor of internal medicine, with its George Engel Award. The award is presented annually for outstanding research contributing to the theory, practice and teaching of effective health-care communication and related skills.

Tarantula venom illuminates electrical activity in live cells

October 20, 2014

Researchers at the University of California, Davis, Lawrence Berkeley National Laboratory and Marine Biological Laboratory in Woods Hole, Massachusetts, have created a cellular probe that combines a tarantula toxin with a fluorescent compound to help scientists observe electrical activity in neurons and other cells. The probe binds to a voltage-activated potassium ion channel subtype, lighting up when the channel is turned off and dimming when it is activated. 

Cancer Center wins $1.7 million NCI grant to study novel cancer treatment

October 10, 2014

A multidisciplinary team at UC Davis will embark on research to determine whether combining a novel type of immunotherapy with radiation and chemotherapy can make treatment for sarcoma, breast and pancreatic cancers more effective.

Probiotic decreases the risk of necrotizing enterocolitis

October 10, 2014

A team of UC Davis and University of Arizona researchers discovered that adding the bacteria Bifidobacterium longum subsp. infantis (B. infantis) to formula fed to newborn rats reduced the incidence of necrotizing enterocolitis, an often deadly intestinal infection.

MIND Institute receives $900,000 grant to study use of sertraline in young children with autism spectrum disorder

October 8, 2014

Focusing on treatments to ameliorate autism symptoms, researchers with the UC Davis MIND Institute will launch the first study to examine the effectiveness of the use of sertraline, commonly known as Zoloft®™, in children as young as 2 to 6 years, through a three-year, $900,000 grant from the U.S. Health Resources and Services Administration (HRSA).

Researchers seeking middle-aged and older men for aging study

October 6, 2014

How alterations in a single gene on the X chromosome affects neurological and psychological functioning in men as they age is the subject of a new study by UC Davis MIND Institute researchers.

September 2014arrow

UC Davis neuroscientists receive prestigious NIH BRAIN Initiative Awards

September 30, 2014

Two UC Davis research teams developing transformational technologies to understand the dynamics of the neural circuitry underlying behavior and cognition have received awards from the federal Brain Research through Advancing Innovative Technologies (BRAIN) Initiative, a presidential grand Challenge enterprise.

Cancer center's Brain Innovation Group funded for brain tumor tool

September 24, 2014

The UC Davis Comprehensive Cancer Center’s Brain Innovation Group has received a grant from the National Cancer Institute (NCI) to improve brain cancer surgery and treatment using UC Davis-developed biophotonic technology.

Higher nurse-to-patient standard improves staff safety

September 23, 2014

A 2004 California law mandating specific nurse-to-patient staffing standards in acute care hospitals significantly lowered job-related injuries and illnesses for both registered nurses and licensed practical nurses, according to a UC Davis study published online in the International Archives of Occupational and Environmental Health.

Mothers of children with autism less likely to have taken iron supplements during pregnancy

September 21, 2014

Mothers of children with autism are significantly less likely to report taking iron supplements before and during their pregnancies than the mothers of children who are developing normally, a study by researchers with the UC Davis MIND Institute has found.

Sleep disorders widely undiagnosed in individuals with multiple sclerosis

September 12, 2014

In what may be the largest study of sleep problems among individuals with multiple sclerosis (MS), researchers at UC Davis have found that widely undiagnosed sleep disorders may be at the root of the most common and disabling symptom of the disease: fatigue.

UC Davis-developed target leukemia treatment shows promise

September 11, 2014

Noriko Satake, UC Davis pediatric oncologist and researcher, has demonstrated in laboratory studies that a new, targeted treatment for leukemia is effective.

Intervention in 6-month-olds with autism ameliorates symptoms, alleviates developmental delay

September 8, 2014

Treatment at the earliest age when signs of autism spectrum disorder (ASD) appear – sometimes in infants as young as 6 months old – significantly reduces symptoms so that, by age 3, most who received the therapy had neither ASD nor developmental delay, a UC Davis MIND Institute research study has found. [español]

Breast vs. bottle feeding in rhesus monkeys

September 3, 2014

Infant rhesus monkeys receiving different diets early in life develop distinct immune systems that persist months after weaning, a study by researchers from UC Davis, the California National Primate Research Center (CNPRC) at UC Davis and UC San Francisco has shown. The study, which compares breast- and bottle-fed infants, appears online September 3 in Science Translational Medicine. [en español]

Brief depression questionnaires could lead to unnecessary antidepressant prescriptions

September 2, 2014

Short questionnaires used to identify patients at risk for depression are linked with antidepressant medications being prescribed when they may not be needed, according to new research from UC Davis Health System published in the September-October issue of the Journal of the American Board of Family Medicine.

August 2014arrow

The early cost of HIV

August 29, 2014

Researchers at UC Davis have made some surprising discoveries about the body’s initial responses to HIV infection. Studying simian immunodeficiency virus (SIV), the team found that specialized cells in the intestine called Paneth cells are early responders to viral invasion and are the source of gut inflammation by producing a cytokine called interleukin-1 beta (IL-1β).

UC Davis MIND Institute researchers launch study examining autism in girls

August 28, 2014

Autism is far more common in boys than girls - affecting 1 in 54 boys and 1 in 252 girls — but little is known about biological differences between boys and girls with autism. A new study, called the ‘Girls with Autism — Imaging of Neurodevelopment’ or GAIN Study, led by researchers at the UC Davis MIND Institute will explore those differences in very young girls with autism.

Introducing the multi-tasking nanoparticle

August 26, 2014

mKit Lam and colleagues from UC Davis and other institutions have created dynamic nanoparticles (NPs) that could provide an arsenal of applications to diagnose and treat cancer. Built on an easy-to-make polymer, these particles can be used as contrast agents to light up tumors for MRI and PET scans or deliver chemo and other therapies to destroy tumors. In addition, the particles are biocompatible and have shown no toxicity. The study was published online today in Nature Communications.

University of California brings researchers together for statewide autism summit

August 13, 2014

Bringing together the research prowess of the University of California to address the increase in autism incidence, its public health impacts, and the need to speed the development of treatments for affected individuals and their families, internationally respected scientists from UC campuses at Irvine, Los Angeles, San Diego, San Francisco and Davis will converge at the UC Davis MIND Institute for a daylong summit on innovative translational neurodevelopmental research.

Novel drug action against solid tumors explained

August 11, 2014

Researchers at UC Davis, City of Hope, Taipai Medical University and National Health Research Institutes in Taiwan have discovered how a drug that deprives the cells of a key amino acid specifically kills cancer cells.

Pan awarded grant to test 'smart' chemotherapy drug for bladder cancer

August 7, 2014

UC Davis Comprehensive Cancer Center oncologist Chong-Xian Pan has received a $650,000 grant from the VA Northern California Health Care System to conduct the first clinical trial of a novel chemotherapy-delivery drug he developed for bladder cancer patients.

Observing brain synapses in action

August 6, 2014

Lin Tian’s fascination with neuroscience stems from a deep curiosity about the complexity and elegance of the human brain. As one of only five scientists in the U.S. and Canada — and the first at UC Davis —to be named a 2014 Rita Allen Foundation Scholar, Tian will be developing optical sensors and applications to acquire fundamental insights about how the nervous system functions in health and disease.

UC Davis nursing dean selected for national gerontological research award

August 5, 2014

Founding Dean for the Betty Irene Moore School of Nursing at UC Davis, Heather M. Young, was recently named the 2014 recipient of the Doris Schwartz Gerontological Nursing Research Award by the nation’s largest interdisciplinary organization devoted to the field of aging — the Gerontological Society of America (GSA).

July 2014arrow

UC Davis nursing school approved for $2.1 million award by the Patient-Centered Outcomes Research Institute

July 31, 2014

A research project led by the Betty Irene Moore School of Nursing at UC Davis was approved for a $2.1 million award by the Patient-Centered Outcomes Research Institute (PCORI) to study improving health for individuals with diabetes.

Experiences at every stage of life contribute to cognitive abilities in old age

July 24, 2014

Early life experiences, such as childhood socioeconomic status and literacy, may have greater influence on the risk of cognitive impairment late in life than such demographic characteristics as race and ethnicity, a large study by researchers with the UC Davis Alzheimer’s Disease Center and the University of Victoria, Canada, has found.

Neither gender nor parenthood force doctors to leave surgery training

July 24, 2014

While having children or being female is often thought to be linked with the decision to leave a general surgery residency, this is not true, according to a 10-year evaluation of UC Davis residents.

UC Davis study researches potential link to care for mothers battling depression: their child's pediatrician

July 21, 2014

Pediatricians will screen mothers for depression in a new research study conducted at UC Davis Children's Hospital. The grant is funded by the National Institute of Mental Health.

MIND Institute researchers seek infants for study on early signs of autism and ADHD

July 18, 2014

UC Davis MIND Institute researchers are seeking participants for a new study that will examine the early development of infants who have an older sibling with autism spectrum disorder, attention-deficit/hyperactivity disorder (ADHD), or who are developing typically. In an effort to detect the earliest signs of developmental problems, the researchers will test a new online screening measure that uses videos to help parents track their infants’ development.

UC Davis researcher receives NSFC grant to find new gastric cancer genes

July 18, 2014

No Stomach for Cancer Foundation (NSFC) has awarded cancer geneticist Luis Carvajal-Carmona a $50,000 grant to study the genetic characteristics of gastric cancer.

'Support cells' in brain play important role in Down syndrome

July 18, 2014

Researchers from UC Davis School of Medicine and Shriners Hospitals for Children – Northern California have identified a group of cells in the brain that they say plays an important role in the abnormal neuron development in Down syndrome.

Medicare reimbursement for surgical procedures poorly reflects reality

July 17, 2014

The current system used to determine Medicare payments for surgeries — called relative value units, or RVUs — poorly correlates with the actual work involved in procedures, new research from UC Davis has found. The authors of the study, which will be published in the August issue of the Journal of Surgical Research, call for a more objective system for determining the value of work done by surgeons.

Neural stem cell discovery may aid in treatment research for deafness

July 15, 2014

Researchers at UC Davis School of Medicine have for the first time shown that a polysialylated glycoprotein that regulates neurodevelopment exists on the surface of cells in the adult inner ear.

UC Davis professor receives award to develop preventive treatment for autism

July 14, 2014

The Hartwell Foundation has presented an Individual Biomedical Research Award to Professor Judy A. Van de Water of the University of California, Davis, recognizing research that could affect nearly one in every four cases of autism among children in the U.S.

New combination drug controls tumor growth and metastasis in mice

July 14, 2014

Researchers at UC Davis, University of Massachusetts and Harvard Medical School have created a combination drug that controls both tumor growth and metastasis. By combining a COX-2 inhibitor, similar to Celebrex, and an epoxide hydrolase (sEH) inhibitor, the drug controls angiogenesis (blood vessel formation), limiting a tumor’s ability to grow and spread. The study appears today in the journal Proceedings of the National Academy of Sciences.

Pancreatic surgery complications impact hospital costs more than length of stay

July 10, 2014

When it comes to a specific type of pancreatic surgery, post-operative complications have a far greater impact on total cost than does how long the patient stays in the hospital, according to a published paper by UC Davis researchers.

Minor head injury not reason enough for CT scan in children

July 7, 2014

A nationwide study of more than 40,000 children evaluated in hospital emergency departments for head trauma found that if children had only loss of consciousness, and no other signs or symptoms related to the head trauma, they are very unlikely to have sustained serious brain injuries. Children who have only isolated loss of consciousness after head trauma do not routinely require computed tomography (CT) scans of the head, reported researchers from UC Davis Health System and Boston Children’s Hospital. 

Sickle cell drug passes early phase trial

July 2, 2014

A potentially groundbreaking investigational drug designed to treat the painful vaso-occlusive crises that are the hallmark of sickle cell disease has been found to be safe following a clinical trial at UC Davis.

June 2014arrow

Surgical biopsy proves safe for selected late-stage lung cancer patients

June 26, 2014

Researchers at UC Davis have determined that surgical biopsies can be safely performed on select patients with late-stage non-small cell lung cancer, which should enhance their access to drugs that target specific genetic mutations such as epidermal growth factor receptor (EGFR).

Cancer Center's specialty pharmacy program helps patients adhere to oral chemotherapy

June 24, 2014

A UC Davis program designed to better manage cancer patients taking oral chemotherapy drugs has demonstrated that one-on-one counseling, education and monitoring can improve adherence to potentially life-saving cancer treatments.

UC Davis MIND Institute study finds association between maternal exposure to agricultural pesticides, autism in offspring

June 22, 2014

Pregnant women who lived in close proximity to fields and farms where chemical pesticides were applied experienced a two-thirds increased risk of having a child with autism spectrum disorder or other developmental delay, a study by researchers with the UC Davis MIND Institute has found. The associations were stronger when the exposures occurred during the second and third trimesters of the women’s pregnancies. [en español]

Groundbreaking lung cancer trial launched

June 16, 2014

UC Davis Comprehensive Cancer Center patients will soon be part of an unprecedented clinical trial designed to improve access to promising therapies and speed development of effective treatments for an advanced form of lung cancer, the leading cancer killer of both men and women.

Fungal protein found to cross blood-brain barrier

June 11, 2014

In a remarkable series of experiments on a fungus that causes cryptococcal meningitis, a deadly infection of the membranes that cover the spinal cord and brain, investigators at UC Davis have isolated a protein that appears to be responsible for the fungus’ ability to cross from the bloodstream into the brain.

Violent crimes could be prevented if felony charges were reduced less often, study finds

June 10, 2014

A UC Davis study comparing violent misdemeanor convictions with their original criminal charges has found that subsequent violent crimes could be prevented if criminal charges were reduced less often during plea bargaining.

May 2014arrow

UC Davis study supports the use of bone-stabilizing devices for sternal repairs

May 30, 2014

Devices made of metal plates and screws that can precisely align and stabilize fractured bones as they heal can safely and effectively repair the sternum, according to a review of UC Davis surgeries published in the May issue of the Annals of Plastic Surgery.

UC Davis professor selected to work with international team on cancer

May 29, 2014

Paramita Ghosh, a UC Davis associate professor and expert in signal transduction pathways in prostate cancer, has been selected as one of 350 scientists to work on a project that aims to reduce public exposure to environmental agents that can lead to cancer and that hopes to inspire research into multi-faceted approaches to cancer prevention, treatment and prolonged survival.

Different approaches needed to control cardiovascular disease risks for those with HIV

May 14, 2014

Even if treated, hypertension and high cholesterol are common for people with human immunodeficiency virus (HIV), according to a new study from researchers at Mount Sinai St. Luke’s and Mount Sinai Roosevelt hospitals in New York and the University of California, Davis.

Tailored intervention has low impact on colorectal cancer screening

May 12, 2014

Colorectal cancer screening saves lives, but too few people get tested. In an effort to increase these numbers,researchers from UC Davis and elsewhere investigated whether an individualized interactive multimedia computer program (IMCP) would spur patients to get screened.

Study confirms mitochondrial deficits in children with autism

May 8, 2014

Children with autism experience deficits in a type of immune cell that protects the body from infection. Called granulocytes, the cells exhibit one-third the capacity to fight infection and protect the body from invasion compared to the same cells in children who are developing normally.

April 2014arrow

Athena becomes first health network to adopt electric data sharing standard for cancer

April 30, 2014

The five University of California medical centers and their affiliates participating in the Athena Breast Health Network are using a new guide for sharing electronic data for breast cancer treatment. Developed by the American Society of Clinical Oncology (ASCO) and approved through ASCO's Health Level Seven International committee (HL7), the guide will become a national data exchange standard. With the guide, Athena can utilize structured data capture tools for coordination of care, registry submission and research.

Recipe for poor wound healing: bacterial infection plus stress

April 28, 2014

The stress hormone epinephrine – the source of the “fight-or-flight” response – also heightens stresses at the cellular level, inhibiting wound healing and promoting a state of chronic inflammation that prohibits the body’s stem cells from migrating to a wound to encourage skin regeneration, UC Davis researchers have found.

Children with Down syndrome have better heart surgery outcomes

April 22, 2014

Researchers at UC Davis Children’s Hospital have shown that children with Down syndrome have significantly better in-hospital survival rates after surgeries for congenital heart disease (CHD) than their genetically typical peers.

Risk of pregnancy greater with newer method of female sterilization

April 22, 2014

The risk of pregnancy among women using a newer method of planned sterilization called hysteroscopic sterilization is more than 10 times greater over a10-year period than using more commonly performed laparoscopic sterilization, a study by researchers with Yale University and UC Davis has found.

Progressive neurodegenerative disorder linked to R-loop formation, UC Davis researchers find

April 17, 2014

Researchers at UC Davis have identified a new feature of the genetic mutation responsible for the progressive neurodegenerative disorder, fragile X-associated tremor/ataxia syndrome (FXTAS) — the formation of “R-loops,” which they believe may be associated with the disorder’s neurological symptoms, such as tremors, lack of balance, features of parkinsonism, and cognitive decline.

Dual Role: Key cell division proteins also power up mitochondria

April 17, 2014

An international team led by researchers at UC Davis has shown that the cyclin B1/Cdk1 protein complex, which plays a key role in cell division, also boosts the mitochondrial activity to power that process. This is the first time the complex has been shown to perform both jobs. This newfound ability could make cyclin B1/Cdk1 an excellent target to control cellular energy production, potentially advancing cancer care and regenerative medicine. The research was published online today in the journal Developmental Cell.

SSRI use during pregnancy is associated with risk of autism, developmental delays in male children

April 14, 2014

Prenatal exposure to selective serotonin reuptake inhibitors (SSRIs), medications frequently prescribed to treat depression, anxiety and other mental-health disorders, is associated with a higher incidence of autism spectrum disorder (ASD) and developmental delays (DD) in male children, a study of nearly 1,000 mother-child pairs has found.

The vast majority of injuries and illnesses in agriculture are not counted

April 8, 2014

Federal agencies responsible for tracking workplace hazards fail to report 77 percent of the injuries and illnesses of U.S. agricultural workers and farmers, new research from UC Davis has found. [en español]

UC Davis researchers discover how high blood pressure damages the heart

April 7, 2014

A multidisciplinary research team at UC Davis has found a key biological trigger — a protein known as nitric oxide synthase, or NOS — that makes the heart beat stronger in response to higher blood pressure, along with a way to turn that trigger off when it becomes overactive.

UC Davis clinical trials -- helping revolutionize hepatitis C treatment

April 3, 2014

Jesse De La Cruz didn’t have any hepatitis C symptoms for nearly 15 years. Physicians say that’s fairly typical of an illness also known as “the silent killer.”

New test makes Parkinson's-like disorder of middle age detectable in young adulthood

April 2, 2014

The very earliest signs of a debilitating neurodegenerative disorder, in which physical symptoms are not apparent until the fifth decade of life, are detectable in individuals as young as 30 years old using a new, sophisticated type of neuroimaging, researchers at UC Davis, the University of Illinois and UCLA have found.