Office of the Vice Chancellor and Dean | UC Davis Health

Welcome Dr. David Lubarsky to UC Davis Health!

David A. LubarskyUC Davis Chancellor Gary May has appointed David A. Lubarsky to the position of vice chancellor of human health sciences and chief executive officer of UC Davis Health, which includes the School of Medicine, the Betty Irene Moore School of Nursing, the 1,000-member physician practice group, and UC Davis Medical Center, a 627-bed acute-care hospital. Lubarsky will join UC Davis on July 2, 2018.

Lubarsky most recently served as the chief medical and systems integration officer with the University of Miami Health System, a position he has held since 2012. As a leader within the system, he has overseen the system’s four hospital and practice chief medical officers as well as patient safety and quality. In addition, he led the university’s self-insured malpractice program, which focuses on prevention, and patient and visitor services, including patient experience. During his tenure at the University of Miami, Lubarsky integrated programs to create system-wide consistent approaches to care and quality improvement, including a new central safety and quality office, a system-wide safety and quality governing board, a system-wide chief medical officer council, a system-wide infection control and antibiotic stewardship program, and a central PI and project management office.

"David brings to UC Davis broad experience and proven results in a major healthcare market," May said. "He has an impressive record of sound financial management and innovative practices for a high functioning health care system that has gained national attention. His success in raising funds to meet pressing needs, including for enhanced access to Medicaid and indigent patients, aligns well with our values at UC Davis Health."

Lubarsky has been recognized for his success in helping establish a centralized scheduling system, improving infrastructure, and improving performance across many areas of the University of Miami health system. He raised more than $100 million annually for the University of Miami from state and federal funding sources to aid enhanced access for Medicaid and indigent patients. Previously, as CEO of the 1,100-physician practice, he turned a $100 million loss into a $32 million surplus in one year by growing patient volumes and optimizing the revenue cycle while making sure already high patient experience scores were maintained. Of note, every one of his major initiatives has explicitly prioritized quality and empathetic patient care.

In his efforts to meet community needs, Lubarsky has worked with the state of Florida and Centers for Medicare & Medicaid Services to expand access to Medicaid, forging a close partnership with the other major academic centers in Florida in pursuit of this goal. He has also been working with Florida’s state and congressional representatives to expand existing graduate medical education programs that would best meet the state’s needs and to secure the necessary federal funding which has been frozen for more than 20 years.

For the last 16 years, Lubarsky has been chief of service of anesthesia and pain management for the largest safety net hospital in the U.S., Jackson Memorial Hospital. He served on their board overseeing safety and quality, and throughout his tenure has been a forceful advocate for a uniform high quality of care.

"It is a privilege to join this highly regarded, progressive and nationally recognized health system," Lubarsky said. "I look forward to working closely with the accomplished faculty and staff, and routinely interacting with Davis’ talented students and trainees. I have already heard many great ideas about how to catapult Davis to greater heights, and I hope to harness those ideas to catalyze innovation so that we better serve our patients, our local community and our academic mission."

UC Davis School of Medicine is one of the nation's leading medical schools, recognized for its research and primary-care programs. Ranked 34th in National Institutes of Health funding in 2013, it is designated as one of the nation’s inaugural Clinical Translational Science Centers.

A few highlights include:

  • A national reputation for life-changing biomedical discoveries
  • A passion for clinical care and a commitment to engaging people from underserved communities and advancing rural health
  • Fully accredited master’s degree programs in public health and in informatics
  • A combined M.D.-Ph.D. program that is training the next generation of physician-scientists to conduct high-impact research and translate discoveries into better clinical care

The Dean’s Departments and Offices include:

Additional departments:

To learn more, visit the medical school site.

UC Davis Medical Center, based in Sacramento, Calif., is a nationally renowned academic medical center where clinical practice, teaching and research converge to advance human health.

A few highlights:

  • A 627-bed multispecialty academic medical center
  • Serves 33 counties covering a 65,000-square-mile area north to the Oregon border and east to Nevada
  • Recognized as one of the “Most Wired” hospitals in the U.S.
  • Recognized by The Leapfrog Group as a “Top Hospital” for delivery of high-quality care
  • Ranked Sacramento's top hospital by U.S. News & World Report

Centers of excellence include:

  • UC Davis Comprehensive Cancer Center, one of only 41 National Cancer Institute-designated comprehensive centers nationwide
  • State-of-the-art emergency departments that include the region's only Level I adult and pediatric trauma centers
  • The internationally recognized UC Davis MIND Institute, devoted to finding treatments and cures for neurodevelopmental disorders
  • UC Davis Children's Hospital, a nationally ranked pediatric hospital with more than 120 physicians in 33 pediatric subspecialties
  • A pioneering telehealth program, which gives remote, underserved communities access to academic specialty and subspecialty care

To learn more, visit the medical center site.

The Betty Irene Moore School of Nursing at UC Davis cultivates academic excellence and addresses urgent, societal needs through leadership development, interprofessional education, transformative research, cultural inclusiveness and innovative technology. The school plays a critical role in preparing nurse leaders who will shape the future of health care and inform health policy.

The School of Nursing has five research focus areas: chronic disease management, health technology, pain management, Healthy People and Healthy Systems. Faculty come from a wide range of backgrounds including nursing, business administration, sociology, gerontology, medicine, information technology and psychology. School of Nursing students engage in classroom and clinical environments with students in the School of Medicine, health informatics and other health-related programs.

A few highlights include:

To learn more, visit the School of Nursing’s website.

The Practice Management Group (TPMG) represents all organized medical group practices of UC Davis Health System’s primary and specialty care faculty physicians. The group's purpose is to serve the health system’s missions through high-quality, cost-effective care delivery. By delegation from the Office of the Vice Chancellor and Dean, TPMG has shared responsibility for the clinical operations of the health system's professional practice activities.

The formation of TPMG is an important step in formalizing the leadership of the health system's medical group practices and in refining the role of its group practice in achieving the health system's research, teaching, patient care and community engagement goals. Its primary goal is to maintain a clinical practice that distinguishes UC Davis Health System as a leading faculty and academic health center.

Specific goals of TPMG include:

  • Increasing efficiency of practice and revenue
  • Decreasing practice expenses
  • Reducing silos and improving integration
  • Identifying areas to increase quality
  • Aligning incentives

David H. Wisner is the executive director of the Practice Management Group, overseeing faculty practice operations as well as the overall vision and strategic direction of TPMG and its day-to-day activities. Wisner collaborates with the leadership of the School of Medicine and medical center to set and achieve joint strategic goals across the health system.

More information



Office of the Vice Chancellor and Dean | UC Davis Health

Welcome Dr. David Lubarsky to UC Davis Health!

David A. LubarskyUC Davis Chancellor Gary May has appointed David A. Lubarsky to the position of vice chancellor of human health sciences and chief executive officer of UC Davis Health, which includes the School of Medicine, the Betty Irene Moore School of Nursing, the 1,000-member physician practice group, and UC Davis Medical Center, a 627-bed acute-care hospital. Lubarsky will join UC Davis on July 2, 2018.

Lubarsky most recently served as the chief medical and systems integration officer with the University of Miami Health System, a position he has held since 2012. As a leader within the system, he has overseen the system’s four hospital and practice chief medical officers as well as patient safety and quality. In addition, he led the university’s self-insured malpractice program, which focuses on prevention, and patient and visitor services, including patient experience. During his tenure at the University of Miami, Lubarsky integrated programs to create system-wide consistent approaches to care and quality improvement, including a new central safety and quality office, a system-wide safety and quality governing board, a system-wide chief medical officer council, a system-wide infection control and antibiotic stewardship program, and a central PI and project management office.

"David brings to UC Davis broad experience and proven results in a major healthcare market," May said. "He has an impressive record of sound financial management and innovative practices for a high functioning health care system that has gained national attention. His success in raising funds to meet pressing needs, including for enhanced access to Medicaid and indigent patients, aligns well with our values at UC Davis Health."

Lubarsky has been recognized for his success in helping establish a centralized scheduling system, improving infrastructure, and improving performance across many areas of the University of Miami health system. He raised more than $100 million annually for the University of Miami from state and federal funding sources to aid enhanced access for Medicaid and indigent patients. Previously, as CEO of the 1,100-physician practice, he turned a $100 million loss into a $32 million surplus in one year by growing patient volumes and optimizing the revenue cycle while making sure already high patient experience scores were maintained. Of note, every one of his major initiatives has explicitly prioritized quality and empathetic patient care.

In his efforts to meet community needs, Lubarsky has worked with the state of Florida and Centers for Medicare & Medicaid Services to expand access to Medicaid, forging a close partnership with the other major academic centers in Florida in pursuit of this goal. He has also been working with Florida’s state and congressional representatives to expand existing graduate medical education programs that would best meet the state’s needs and to secure the necessary federal funding which has been frozen for more than 20 years.

For the last 16 years, Lubarsky has been chief of service of anesthesia and pain management for the largest safety net hospital in the U.S., Jackson Memorial Hospital. He served on their board overseeing safety and quality, and throughout his tenure has been a forceful advocate for a uniform high quality of care.

"It is a privilege to join this highly regarded, progressive and nationally recognized health system," Lubarsky said. "I look forward to working closely with the accomplished faculty and staff, and routinely interacting with Davis’ talented students and trainees. I have already heard many great ideas about how to catapult Davis to greater heights, and I hope to harness those ideas to catalyze innovation so that we better serve our patients, our local community and our academic mission."

UC Davis School of Medicine is one of the nation's leading medical schools, recognized for its research and primary-care programs. Ranked 34th in National Institutes of Health funding in 2013, it is designated as one of the nation’s inaugural Clinical Translational Science Centers.

A few highlights include:

  • A national reputation for life-changing biomedical discoveries
  • A passion for clinical care and a commitment to engaging people from underserved communities and advancing rural health
  • Fully accredited master’s degree programs in public health and in informatics
  • A combined M.D.-Ph.D. program that is training the next generation of physician-scientists to conduct high-impact research and translate discoveries into better clinical care

The Dean’s Departments and Offices include:

Additional departments:

To learn more, visit the medical school site.

UC Davis Medical Center, based in Sacramento, Calif., is a nationally renowned academic medical center where clinical practice, teaching and research converge to advance human health.

A few highlights:

  • A 627-bed multispecialty academic medical center
  • Serves 33 counties covering a 65,000-square-mile area north to the Oregon border and east to Nevada
  • Recognized as one of the “Most Wired” hospitals in the U.S.
  • Recognized by The Leapfrog Group as a “Top Hospital” for delivery of high-quality care
  • Ranked Sacramento's top hospital by U.S. News & World Report

Centers of excellence include:

  • UC Davis Comprehensive Cancer Center, one of only 41 National Cancer Institute-designated comprehensive centers nationwide
  • State-of-the-art emergency departments that include the region's only Level I adult and pediatric trauma centers
  • The internationally recognized UC Davis MIND Institute, devoted to finding treatments and cures for neurodevelopmental disorders
  • UC Davis Children's Hospital, a nationally ranked pediatric hospital with more than 120 physicians in 33 pediatric subspecialties
  • A pioneering telehealth program, which gives remote, underserved communities access to academic specialty and subspecialty care

To learn more, visit the medical center site.

The Betty Irene Moore School of Nursing at UC Davis cultivates academic excellence and addresses urgent, societal needs through leadership development, interprofessional education, transformative research, cultural inclusiveness and innovative technology. The school plays a critical role in preparing nurse leaders who will shape the future of health care and inform health policy.

The School of Nursing has five research focus areas: chronic disease management, health technology, pain management, Healthy People and Healthy Systems. Faculty come from a wide range of backgrounds including nursing, business administration, sociology, gerontology, medicine, information technology and psychology. School of Nursing students engage in classroom and clinical environments with students in the School of Medicine, health informatics and other health-related programs.

A few highlights include:

To learn more, visit the School of Nursing’s website.

The Practice Management Group (TPMG) represents all organized medical group practices of UC Davis Health System’s primary and specialty care faculty physicians. The group's purpose is to serve the health system’s missions through high-quality, cost-effective care delivery. By delegation from the Office of the Vice Chancellor and Dean, TPMG has shared responsibility for the clinical operations of the health system's professional practice activities.

The formation of TPMG is an important step in formalizing the leadership of the health system's medical group practices and in refining the role of its group practice in achieving the health system's research, teaching, patient care and community engagement goals. Its primary goal is to maintain a clinical practice that distinguishes UC Davis Health System as a leading faculty and academic health center.

Specific goals of TPMG include:

  • Increasing efficiency of practice and revenue
  • Decreasing practice expenses
  • Reducing silos and improving integration
  • Identifying areas to increase quality
  • Aligning incentives

David H. Wisner is the executive director of the Practice Management Group, overseeing faculty practice operations as well as the overall vision and strategic direction of TPMG and its day-to-day activities. Wisner collaborates with the leadership of the School of Medicine and medical center to set and achieve joint strategic goals across the health system.

More information



Sickle cell drug passes early phase ...
Office of the Vice Chancellor and Dean | UC Davis Health

Welcome Dr. David Lubarsky to UC Davis Health!

David A. LubarskyUC Davis Chancellor Gary May has appointed David A. Lubarsky to the position of vice chancellor of human health sciences and chief executive officer of UC Davis Health, which includes the School of Medicine, the Betty Irene Moore School of Nursing, the 1,000-member physician practice group, and UC Davis Medical Center, a 627-bed acute-care hospital. Lubarsky will join UC Davis on July 2, 2018.

Lubarsky most recently served as the chief medical and systems integration officer with the University of Miami Health System, a position he has held since 2012. As a leader within the system, he has overseen the system’s four hospital and practice chief medical officers as well as patient safety and quality. In addition, he led the university’s self-insured malpractice program, which focuses on prevention, and patient and visitor services, including patient experience. During his tenure at the University of Miami, Lubarsky integrated programs to create system-wide consistent approaches to care and quality improvement, including a new central safety and quality office, a system-wide safety and quality governing board, a system-wide chief medical officer council, a system-wide infection control and antibiotic stewardship program, and a central PI and project management office.

"David brings to UC Davis broad experience and proven results in a major healthcare market," May said. "He has an impressive record of sound financial management and innovative practices for a high functioning health care system that has gained national attention. His success in raising funds to meet pressing needs, including for enhanced access to Medicaid and indigent patients, aligns well with our values at UC Davis Health."

Lubarsky has been recognized for his success in helping establish a centralized scheduling system, improving infrastructure, and improving performance across many areas of the University of Miami health system. He raised more than $100 million annually for the University of Miami from state and federal funding sources to aid enhanced access for Medicaid and indigent patients. Previously, as CEO of the 1,100-physician practice, he turned a $100 million loss into a $32 million surplus in one year by growing patient volumes and optimizing the revenue cycle while making sure already high patient experience scores were maintained. Of note, every one of his major initiatives has explicitly prioritized quality and empathetic patient care.

In his efforts to meet community needs, Lubarsky has worked with the state of Florida and Centers for Medicare & Medicaid Services to expand access to Medicaid, forging a close partnership with the other major academic centers in Florida in pursuit of this goal. He has also been working with Florida’s state and congressional representatives to expand existing graduate medical education programs that would best meet the state’s needs and to secure the necessary federal funding which has been frozen for more than 20 years.

For the last 16 years, Lubarsky has been chief of service of anesthesia and pain management for the largest safety net hospital in the U.S., Jackson Memorial Hospital. He served on their board overseeing safety and quality, and throughout his tenure has been a forceful advocate for a uniform high quality of care.

"It is a privilege to join this highly regarded, progressive and nationally recognized health system," Lubarsky said. "I look forward to working closely with the accomplished faculty and staff, and routinely interacting with Davis’ talented students and trainees. I have already heard many great ideas about how to catapult Davis to greater heights, and I hope to harness those ideas to catalyze innovation so that we better serve our patients, our local community and our academic mission."

UC Davis School of Medicine is one of the nation's leading medical schools, recognized for its research and primary-care programs. Ranked 34th in National Institutes of Health funding in 2013, it is designated as one of the nation’s inaugural Clinical Translational Science Centers.

A few highlights include:

  • A national reputation for life-changing biomedical discoveries
  • A passion for clinical care and a commitment to engaging people from underserved communities and advancing rural health
  • Fully accredited master’s degree programs in public health and in informatics
  • A combined M.D.-Ph.D. program that is training the next generation of physician-scientists to conduct high-impact research and translate discoveries into better clinical care

The Dean’s Departments and Offices include:

Additional departments:

To learn more, visit the medical school site.

UC Davis Medical Center, based in Sacramento, Calif., is a nationally renowned academic medical center where clinical practice, teaching and research converge to advance human health.

A few highlights:

  • A 627-bed multispecialty academic medical center
  • Serves 33 counties covering a 65,000-square-mile area north to the Oregon border and east to Nevada
  • Recognized as one of the “Most Wired” hospitals in the U.S.
  • Recognized by The Leapfrog Group as a “Top Hospital” for delivery of high-quality care
  • Ranked Sacramento's top hospital by U.S. News & World Report

Centers of excellence include:

  • UC Davis Comprehensive Cancer Center, one of only 41 National Cancer Institute-designated comprehensive centers nationwide
  • State-of-the-art emergency departments that include the region's only Level I adult and pediatric trauma centers
  • The internationally recognized UC Davis MIND Institute, devoted to finding treatments and cures for neurodevelopmental disorders
  • UC Davis Children's Hospital, a nationally ranked pediatric hospital with more than 120 physicians in 33 pediatric subspecialties
  • A pioneering telehealth program, which gives remote, underserved communities access to academic specialty and subspecialty care

To learn more, visit the medical center site.

The Betty Irene Moore School of Nursing at UC Davis cultivates academic excellence and addresses urgent, societal needs through leadership development, interprofessional education, transformative research, cultural inclusiveness and innovative technology. The school plays a critical role in preparing nurse leaders who will shape the future of health care and inform health policy.

The School of Nursing has five research focus areas: chronic disease management, health technology, pain management, Healthy People and Healthy Systems. Faculty come from a wide range of backgrounds including nursing, business administration, sociology, gerontology, medicine, information technology and psychology. School of Nursing students engage in classroom and clinical environments with students in the School of Medicine, health informatics and other health-related programs.

A few highlights include:

To learn more, visit the School of Nursing’s website.

The Practice Management Group (TPMG) represents all organized medical group practices of UC Davis Health System’s primary and specialty care faculty physicians. The group's purpose is to serve the health system’s missions through high-quality, cost-effective care delivery. By delegation from the Office of the Vice Chancellor and Dean, TPMG has shared responsibility for the clinical operations of the health system's professional practice activities.

The formation of TPMG is an important step in formalizing the leadership of the health system's medical group practices and in refining the role of its group practice in achieving the health system's research, teaching, patient care and community engagement goals. Its primary goal is to maintain a clinical practice that distinguishes UC Davis Health System as a leading faculty and academic health center.

Specific goals of TPMG include:

  • Increasing efficiency of practice and revenue
  • Decreasing practice expenses
  • Reducing silos and improving integration
  • Identifying areas to increase quality
  • Aligning incentives

David H. Wisner is the executive director of the Practice Management Group, overseeing faculty practice operations as well as the overall vision and strategic direction of TPMG and its day-to-day activities. Wisner collaborates with the leadership of the School of Medicine and medical center to set and achieve joint strategic goals across the health system.

More information



Office of the Vice Chancellor and Dean | UC Davis Health

Welcome Dr. David Lubarsky to UC Davis Health!

David A. LubarskyUC Davis Chancellor Gary May has appointed David A. Lubarsky to the position of vice chancellor of human health sciences and chief executive officer of UC Davis Health, which includes the School of Medicine, the Betty Irene Moore School of Nursing, the 1,000-member physician practice group, and UC Davis Medical Center, a 627-bed acute-care hospital. Lubarsky will join UC Davis on July 2, 2018.

Lubarsky most recently served as the chief medical and systems integration officer with the University of Miami Health System, a position he has held since 2012. As a leader within the system, he has overseen the system’s four hospital and practice chief medical officers as well as patient safety and quality. In addition, he led the university’s self-insured malpractice program, which focuses on prevention, and patient and visitor services, including patient experience. During his tenure at the University of Miami, Lubarsky integrated programs to create system-wide consistent approaches to care and quality improvement, including a new central safety and quality office, a system-wide safety and quality governing board, a system-wide chief medical officer council, a system-wide infection control and antibiotic stewardship program, and a central PI and project management office.

"David brings to UC Davis broad experience and proven results in a major healthcare market," May said. "He has an impressive record of sound financial management and innovative practices for a high functioning health care system that has gained national attention. His success in raising funds to meet pressing needs, including for enhanced access to Medicaid and indigent patients, aligns well with our values at UC Davis Health."

Lubarsky has been recognized for his success in helping establish a centralized scheduling system, improving infrastructure, and improving performance across many areas of the University of Miami health system. He raised more than $100 million annually for the University of Miami from state and federal funding sources to aid enhanced access for Medicaid and indigent patients. Previously, as CEO of the 1,100-physician practice, he turned a $100 million loss into a $32 million surplus in one year by growing patient volumes and optimizing the revenue cycle while making sure already high patient experience scores were maintained. Of note, every one of his major initiatives has explicitly prioritized quality and empathetic patient care.

In his efforts to meet community needs, Lubarsky has worked with the state of Florida and Centers for Medicare & Medicaid Services to expand access to Medicaid, forging a close partnership with the other major academic centers in Florida in pursuit of this goal. He has also been working with Florida’s state and congressional representatives to expand existing graduate medical education programs that would best meet the state’s needs and to secure the necessary federal funding which has been frozen for more than 20 years.

For the last 16 years, Lubarsky has been chief of service of anesthesia and pain management for the largest safety net hospital in the U.S., Jackson Memorial Hospital. He served on their board overseeing safety and quality, and throughout his tenure has been a forceful advocate for a uniform high quality of care.

"It is a privilege to join this highly regarded, progressive and nationally recognized health system," Lubarsky said. "I look forward to working closely with the accomplished faculty and staff, and routinely interacting with Davis’ talented students and trainees. I have already heard many great ideas about how to catapult Davis to greater heights, and I hope to harness those ideas to catalyze innovation so that we better serve our patients, our local community and our academic mission."

UC Davis School of Medicine is one of the nation's leading medical schools, recognized for its research and primary-care programs. Ranked 34th in National Institutes of Health funding in 2013, it is designated as one of the nation’s inaugural Clinical Translational Science Centers.

A few highlights include:

  • A national reputation for life-changing biomedical discoveries
  • A passion for clinical care and a commitment to engaging people from underserved communities and advancing rural health
  • Fully accredited master’s degree programs in public health and in informatics
  • A combined M.D.-Ph.D. program that is training the next generation of physician-scientists to conduct high-impact research and translate discoveries into better clinical care

The Dean’s Departments and Offices include:

Additional departments:

To learn more, visit the medical school site.

UC Davis Medical Center, based in Sacramento, Calif., is a nationally renowned academic medical center where clinical practice, teaching and research converge to advance human health.

A few highlights:

  • A 627-bed multispecialty academic medical center
  • Serves 33 counties covering a 65,000-square-mile area north to the Oregon border and east to Nevada
  • Recognized as one of the “Most Wired” hospitals in the U.S.
  • Recognized by The Leapfrog Group as a “Top Hospital” for delivery of high-quality care
  • Ranked Sacramento's top hospital by U.S. News & World Report

Centers of excellence include:

  • UC Davis Comprehensive Cancer Center, one of only 41 National Cancer Institute-designated comprehensive centers nationwide
  • State-of-the-art emergency departments that include the region's only Level I adult and pediatric trauma centers
  • The internationally recognized UC Davis MIND Institute, devoted to finding treatments and cures for neurodevelopmental disorders
  • UC Davis Children's Hospital, a nationally ranked pediatric hospital with more than 120 physicians in 33 pediatric subspecialties
  • A pioneering telehealth program, which gives remote, underserved communities access to academic specialty and subspecialty care

To learn more, visit the medical center site.

The Betty Irene Moore School of Nursing at UC Davis cultivates academic excellence and addresses urgent, societal needs through leadership development, interprofessional education, transformative research, cultural inclusiveness and innovative technology. The school plays a critical role in preparing nurse leaders who will shape the future of health care and inform health policy.

The School of Nursing has five research focus areas: chronic disease management, health technology, pain management, Healthy People and Healthy Systems. Faculty come from a wide range of backgrounds including nursing, business administration, sociology, gerontology, medicine, information technology and psychology. School of Nursing students engage in classroom and clinical environments with students in the School of Medicine, health informatics and other health-related programs.

A few highlights include:

To learn more, visit the School of Nursing’s website.

The Practice Management Group (TPMG) represents all organized medical group practices of UC Davis Health System’s primary and specialty care faculty physicians. The group's purpose is to serve the health system’s missions through high-quality, cost-effective care delivery. By delegation from the Office of the Vice Chancellor and Dean, TPMG has shared responsibility for the clinical operations of the health system's professional practice activities.

The formation of TPMG is an important step in formalizing the leadership of the health system's medical group practices and in refining the role of its group practice in achieving the health system's research, teaching, patient care and community engagement goals. Its primary goal is to maintain a clinical practice that distinguishes UC Davis Health System as a leading faculty and academic health center.

Specific goals of TPMG include:

  • Increasing efficiency of practice and revenue
  • Decreasing practice expenses
  • Reducing silos and improving integration
  • Identifying areas to increase quality
  • Aligning incentives

David H. Wisner is the executive director of the Practice Management Group, overseeing faculty practice operations as well as the overall vision and strategic direction of TPMG and its day-to-day activities. Wisner collaborates with the leadership of the School of Medicine and medical center to set and achieve joint strategic goals across the health system.

More information



NEWS | July 2, 2014

Sickle cell drug passes early phase trial

(SACRAMENTO, Calif.)

A potentially groundbreaking investigational drug designed to treat the painful vaso-occlusive crises that are the hallmark of sickle cell disease has been found to be safe following a clinical trial at UC Davis.

Ted Wun Ted Wun

Vaso-occlusive crises, during which red blood cells slump together and impede blood flow, cause agonizing pain for people with sickle cell disease. The Phase I clinical trial found the drug, called GMI 1070, safe, maintaining adequate blood concentrations, a key milestone for therapeutic benefit.

Published online today in the journal Public Library of Science ONE (PLoS ONE), the study did not focus on the drug’s efficacy. However, there was evidence that it did improve blood flow and reduced the markers of cell activation, said Ted Wun, associate dean for research at the UC Davis School of Medicine.

“These are encouraging results,” said Wun. “Vaso-occlusive crises cause around 70,000-80,000 hospitalizations each year, and there are currently no specific treatments.”

Sickle cell disease is a chronic condition that affects approximately 100,000 people in the United State, mostly African Americans, and many more around the world. The disease can affect any organ, particularly kidneys, lungs and spleen. Patients experience many severe complications, including stroke, infections, pulmonary arterial hypertension and heart failure.

The disease is caused by abnormal hemoglobin, which change the shape of red blood cells into the tell-tale sickle shape. These misshapen red blood cells are both stiffer and stickier. Cell-adhesion proteins called selectins, which normally mediate interactions between cells, contribute to this abnormal stickiness. As a result, cells clump together and reduce blood flow, precipitating a vaso-occlusive crisis. The resultant severe pain is generally centered in the hips, back, and proximal long bones. However, abdominal and chest pain is also common.

“White blood cells bind to inflamed blood vessel walls and sickle red cells stick to white cells, but interestingly the initiating event is the white cells,” said Wun. “If we could interrupt that white cell interaction, we could stop the cycle that leads to vaso-occlusions.”

GMI 1070 is designed to do just that. By mimicking sugars attached to selectin proteins, which mediate the proteins’ stickiness, the drug inhibits three different selectins (L-, E- and P-selectin), increasing blood flow in animal models. However, the first round of human clinical trials was primarily focused on the drug’s safety and pharmacokinetics. In other words, the researchers wanted to know if there were any severe side effects and whether the drug maintained adequate concentrations in the blood.

The trial included 15 sickle cell patients, five of whom were enrolled at UC Davis’s National Institutes of Health-supported Clinical and Translational Science Center. Overall, the drug was well tolerated, with only 16 complications, primarily headaches. With one exception, all complications were grade 1 or 2, the least severe. No participants discontinued the drug.

In the pharmacokinetic tests, patients were given a loading dose followed by smaller maintenance doses, which successfully maintained GMI 1070 blood concentrations.

Though secondary to safety and pharmacokinetics, the trial also showed marked decreases in P- and E-selectins, as well as other markers associated with coagulation and inflammation. The study also found small increases in blood flow.

In addition to these findings, a randomized double-blind phase II trial for GMI 1070 has also been completed. Preliminary results have been positive, and the study has been submitted for publication. A phase III trial currently is being planned.

“Vaso-occlusive crises generate intense pain and suffering,” said Wun. “If the phase III study confirms that GMI 1070 is effective, it would be a huge advance for the sickle cell community.”

GMI 1070 (trade name Rivipansel) is produced by GlycoMimetics, Inc., a biotechnology company based in Gaithersburg, Maryland.The company sponsored the trial.

Other investigators included Anthony Cheung at UC Davis, Lori Styles and Frans Kuypers at Children’s Hospital and Research Institute Oakland, Laura DeCastro, Marilyn J. Telen at Duke University, William Kramer at, Kramer Consulting, LLC, Seungshin Rhee at Rho Inc., and Henry Flanner, John L. Magnani and Helen Thackray at GlycoMimetics, Inc.

UC Davis Health System is improving lives and transforming health care by providing excellent patient care, conducting groundbreaking research, fostering innovative, interprofessional education, and creating dynamic, productive partnerships with the community. The academic health system includes one of the country's best medical schools, a 619-bed acute-care teaching hospital, a 1000-member physician's practice group and the new Betty Irene Moore School of Nursing. It is home to a National Cancer Institute-designated comprehensive cancer center, an international neurodevelopmental institute, a stem cell institute and a comprehensive children's hospital. Other nationally prominent centers focus on advancing telemedicine, improving vascular care, eliminating health disparities and translating research findings into new treatments for patients. Together, they make UC Davis a hub of innovation that is transforming health for all. For more information, visit healthsystem.ucdavis.edu.

Office of the Vice Chancellor and Dean | UC Davis Health

Welcome Dr. David Lubarsky to UC Davis Health!

David A. LubarskyUC Davis Chancellor Gary May has appointed David A. Lubarsky to the position of vice chancellor of human health sciences and chief executive officer of UC Davis Health, which includes the School of Medicine, the Betty Irene Moore School of Nursing, the 1,000-member physician practice group, and UC Davis Medical Center, a 627-bed acute-care hospital. Lubarsky will join UC Davis on July 2, 2018.

Lubarsky most recently served as the chief medical and systems integration officer with the University of Miami Health System, a position he has held since 2012. As a leader within the system, he has overseen the system’s four hospital and practice chief medical officers as well as patient safety and quality. In addition, he led the university’s self-insured malpractice program, which focuses on prevention, and patient and visitor services, including patient experience. During his tenure at the University of Miami, Lubarsky integrated programs to create system-wide consistent approaches to care and quality improvement, including a new central safety and quality office, a system-wide safety and quality governing board, a system-wide chief medical officer council, a system-wide infection control and antibiotic stewardship program, and a central PI and project management office.

"David brings to UC Davis broad experience and proven results in a major healthcare market," May said. "He has an impressive record of sound financial management and innovative practices for a high functioning health care system that has gained national attention. His success in raising funds to meet pressing needs, including for enhanced access to Medicaid and indigent patients, aligns well with our values at UC Davis Health."

Lubarsky has been recognized for his success in helping establish a centralized scheduling system, improving infrastructure, and improving performance across many areas of the University of Miami health system. He raised more than $100 million annually for the University of Miami from state and federal funding sources to aid enhanced access for Medicaid and indigent patients. Previously, as CEO of the 1,100-physician practice, he turned a $100 million loss into a $32 million surplus in one year by growing patient volumes and optimizing the revenue cycle while making sure already high patient experience scores were maintained. Of note, every one of his major initiatives has explicitly prioritized quality and empathetic patient care.

In his efforts to meet community needs, Lubarsky has worked with the state of Florida and Centers for Medicare & Medicaid Services to expand access to Medicaid, forging a close partnership with the other major academic centers in Florida in pursuit of this goal. He has also been working with Florida’s state and congressional representatives to expand existing graduate medical education programs that would best meet the state’s needs and to secure the necessary federal funding which has been frozen for more than 20 years.

For the last 16 years, Lubarsky has been chief of service of anesthesia and pain management for the largest safety net hospital in the U.S., Jackson Memorial Hospital. He served on their board overseeing safety and quality, and throughout his tenure has been a forceful advocate for a uniform high quality of care.

"It is a privilege to join this highly regarded, progressive and nationally recognized health system," Lubarsky said. "I look forward to working closely with the accomplished faculty and staff, and routinely interacting with Davis’ talented students and trainees. I have already heard many great ideas about how to catapult Davis to greater heights, and I hope to harness those ideas to catalyze innovation so that we better serve our patients, our local community and our academic mission."

UC Davis School of Medicine is one of the nation's leading medical schools, recognized for its research and primary-care programs. Ranked 34th in National Institutes of Health funding in 2013, it is designated as one of the nation’s inaugural Clinical Translational Science Centers.

A few highlights include:

  • A national reputation for life-changing biomedical discoveries
  • A passion for clinical care and a commitment to engaging people from underserved communities and advancing rural health
  • Fully accredited master’s degree programs in public health and in informatics
  • A combined M.D.-Ph.D. program that is training the next generation of physician-scientists to conduct high-impact research and translate discoveries into better clinical care

The Dean’s Departments and Offices include:

Additional departments:

To learn more, visit the medical school site.

UC Davis Medical Center, based in Sacramento, Calif., is a nationally renowned academic medical center where clinical practice, teaching and research converge to advance human health.

A few highlights:

  • A 627-bed multispecialty academic medical center
  • Serves 33 counties covering a 65,000-square-mile area north to the Oregon border and east to Nevada
  • Recognized as one of the “Most Wired” hospitals in the U.S.
  • Recognized by The Leapfrog Group as a “Top Hospital” for delivery of high-quality care
  • Ranked Sacramento's top hospital by U.S. News & World Report

Centers of excellence include:

  • UC Davis Comprehensive Cancer Center, one of only 41 National Cancer Institute-designated comprehensive centers nationwide
  • State-of-the-art emergency departments that include the region's only Level I adult and pediatric trauma centers
  • The internationally recognized UC Davis MIND Institute, devoted to finding treatments and cures for neurodevelopmental disorders
  • UC Davis Children's Hospital, a nationally ranked pediatric hospital with more than 120 physicians in 33 pediatric subspecialties
  • A pioneering telehealth program, which gives remote, underserved communities access to academic specialty and subspecialty care

To learn more, visit the medical center site.

The Betty Irene Moore School of Nursing at UC Davis cultivates academic excellence and addresses urgent, societal needs through leadership development, interprofessional education, transformative research, cultural inclusiveness and innovative technology. The school plays a critical role in preparing nurse leaders who will shape the future of health care and inform health policy.

The School of Nursing has five research focus areas: chronic disease management, health technology, pain management, Healthy People and Healthy Systems. Faculty come from a wide range of backgrounds including nursing, business administration, sociology, gerontology, medicine, information technology and psychology. School of Nursing students engage in classroom and clinical environments with students in the School of Medicine, health informatics and other health-related programs.

A few highlights include:

To learn more, visit the School of Nursing’s website.

The Practice Management Group (TPMG) represents all organized medical group practices of UC Davis Health System’s primary and specialty care faculty physicians. The group's purpose is to serve the health system’s missions through high-quality, cost-effective care delivery. By delegation from the Office of the Vice Chancellor and Dean, TPMG has shared responsibility for the clinical operations of the health system's professional practice activities.

The formation of TPMG is an important step in formalizing the leadership of the health system's medical group practices and in refining the role of its group practice in achieving the health system's research, teaching, patient care and community engagement goals. Its primary goal is to maintain a clinical practice that distinguishes UC Davis Health System as a leading faculty and academic health center.

Specific goals of TPMG include:

  • Increasing efficiency of practice and revenue
  • Decreasing practice expenses
  • Reducing silos and improving integration
  • Identifying areas to increase quality
  • Aligning incentives

David H. Wisner is the executive director of the Practice Management Group, overseeing faculty practice operations as well as the overall vision and strategic direction of TPMG and its day-to-day activities. Wisner collaborates with the leadership of the School of Medicine and medical center to set and achieve joint strategic goals across the health system.

More information