Office of the Vice Chancellor and Dean | UC Davis Health

Welcome Dr. David Lubarsky to UC Davis Health!

David A. LubarskyUC Davis Chancellor Gary May has appointed David A. Lubarsky to the position of vice chancellor of human health sciences and chief executive officer of UC Davis Health, which includes the School of Medicine, the Betty Irene Moore School of Nursing, the 1,000-member physician practice group, and UC Davis Medical Center, a 627-bed acute-care hospital. Lubarsky will join UC Davis on July 2, 2018.

Lubarsky most recently served as the chief medical and systems integration officer with the University of Miami Health System, a position he has held since 2012. As a leader within the system, he has overseen the system’s four hospital and practice chief medical officers as well as patient safety and quality. In addition, he led the university’s self-insured malpractice program, which focuses on prevention, and patient and visitor services, including patient experience. During his tenure at the University of Miami, Lubarsky integrated programs to create system-wide consistent approaches to care and quality improvement, including a new central safety and quality office, a system-wide safety and quality governing board, a system-wide chief medical officer council, a system-wide infection control and antibiotic stewardship program, and a central PI and project management office.

"David brings to UC Davis broad experience and proven results in a major healthcare market," May said. "He has an impressive record of sound financial management and innovative practices for a high functioning health care system that has gained national attention. His success in raising funds to meet pressing needs, including for enhanced access to Medicaid and indigent patients, aligns well with our values at UC Davis Health."

Lubarsky has been recognized for his success in helping establish a centralized scheduling system, improving infrastructure, and improving performance across many areas of the University of Miami health system. He raised more than $100 million annually for the University of Miami from state and federal funding sources to aid enhanced access for Medicaid and indigent patients. Previously, as CEO of the 1,100-physician practice, he turned a $100 million loss into a $32 million surplus in one year by growing patient volumes and optimizing the revenue cycle while making sure already high patient experience scores were maintained. Of note, every one of his major initiatives has explicitly prioritized quality and empathetic patient care.

In his efforts to meet community needs, Lubarsky has worked with the state of Florida and Centers for Medicare & Medicaid Services to expand access to Medicaid, forging a close partnership with the other major academic centers in Florida in pursuit of this goal. He has also been working with Florida’s state and congressional representatives to expand existing graduate medical education programs that would best meet the state’s needs and to secure the necessary federal funding which has been frozen for more than 20 years.

For the last 16 years, Lubarsky has been chief of service of anesthesia and pain management for the largest safety net hospital in the U.S., Jackson Memorial Hospital. He served on their board overseeing safety and quality, and throughout his tenure has been a forceful advocate for a uniform high quality of care.

"It is a privilege to join this highly regarded, progressive and nationally recognized health system," Lubarsky said. "I look forward to working closely with the accomplished faculty and staff, and routinely interacting with Davis’ talented students and trainees. I have already heard many great ideas about how to catapult Davis to greater heights, and I hope to harness those ideas to catalyze innovation so that we better serve our patients, our local community and our academic mission."

UC Davis School of Medicine is one of the nation's leading medical schools, recognized for its research and primary-care programs. Ranked 34th in National Institutes of Health funding in 2013, it is designated as one of the nation’s inaugural Clinical Translational Science Centers.

A few highlights include:

  • A national reputation for life-changing biomedical discoveries
  • A passion for clinical care and a commitment to engaging people from underserved communities and advancing rural health
  • Fully accredited master’s degree programs in public health and in informatics
  • A combined M.D.-Ph.D. program that is training the next generation of physician-scientists to conduct high-impact research and translate discoveries into better clinical care

The Dean’s Departments and Offices include:

Additional departments:

To learn more, visit the medical school site.

UC Davis Medical Center, based in Sacramento, Calif., is a nationally renowned academic medical center where clinical practice, teaching and research converge to advance human health.

A few highlights:

  • A 627-bed multispecialty academic medical center
  • Serves 33 counties covering a 65,000-square-mile area north to the Oregon border and east to Nevada
  • Recognized as one of the “Most Wired” hospitals in the U.S.
  • Recognized by The Leapfrog Group as a “Top Hospital” for delivery of high-quality care
  • Ranked Sacramento's top hospital by U.S. News & World Report

Centers of excellence include:

  • UC Davis Comprehensive Cancer Center, one of only 41 National Cancer Institute-designated comprehensive centers nationwide
  • State-of-the-art emergency departments that include the region's only Level I adult and pediatric trauma centers
  • The internationally recognized UC Davis MIND Institute, devoted to finding treatments and cures for neurodevelopmental disorders
  • UC Davis Children's Hospital, a nationally ranked pediatric hospital with more than 120 physicians in 33 pediatric subspecialties
  • A pioneering telehealth program, which gives remote, underserved communities access to academic specialty and subspecialty care

To learn more, visit the medical center site.

The Betty Irene Moore School of Nursing at UC Davis cultivates academic excellence and addresses urgent, societal needs through leadership development, interprofessional education, transformative research, cultural inclusiveness and innovative technology. The school plays a critical role in preparing nurse leaders who will shape the future of health care and inform health policy.

The School of Nursing has five research focus areas: chronic disease management, health technology, pain management, Healthy People and Healthy Systems. Faculty come from a wide range of backgrounds including nursing, business administration, sociology, gerontology, medicine, information technology and psychology. School of Nursing students engage in classroom and clinical environments with students in the School of Medicine, health informatics and other health-related programs.

A few highlights include:

To learn more, visit the School of Nursing’s website.

The Practice Management Group (TPMG) represents all organized medical group practices of UC Davis Health System’s primary and specialty care faculty physicians. The group's purpose is to serve the health system’s missions through high-quality, cost-effective care delivery. By delegation from the Office of the Vice Chancellor and Dean, TPMG has shared responsibility for the clinical operations of the health system's professional practice activities.

The formation of TPMG is an important step in formalizing the leadership of the health system's medical group practices and in refining the role of its group practice in achieving the health system's research, teaching, patient care and community engagement goals. Its primary goal is to maintain a clinical practice that distinguishes UC Davis Health System as a leading faculty and academic health center.

Specific goals of TPMG include:

  • Increasing efficiency of practice and revenue
  • Decreasing practice expenses
  • Reducing silos and improving integration
  • Identifying areas to increase quality
  • Aligning incentives

David H. Wisner is the executive director of the Practice Management Group, overseeing faculty practice operations as well as the overall vision and strategic direction of TPMG and its day-to-day activities. Wisner collaborates with the leadership of the School of Medicine and medical center to set and achieve joint strategic goals across the health system.

More information



Office of the Vice Chancellor and Dean | UC Davis Health

Welcome Dr. David Lubarsky to UC Davis Health!

David A. LubarskyUC Davis Chancellor Gary May has appointed David A. Lubarsky to the position of vice chancellor of human health sciences and chief executive officer of UC Davis Health, which includes the School of Medicine, the Betty Irene Moore School of Nursing, the 1,000-member physician practice group, and UC Davis Medical Center, a 627-bed acute-care hospital. Lubarsky will join UC Davis on July 2, 2018.

Lubarsky most recently served as the chief medical and systems integration officer with the University of Miami Health System, a position he has held since 2012. As a leader within the system, he has overseen the system’s four hospital and practice chief medical officers as well as patient safety and quality. In addition, he led the university’s self-insured malpractice program, which focuses on prevention, and patient and visitor services, including patient experience. During his tenure at the University of Miami, Lubarsky integrated programs to create system-wide consistent approaches to care and quality improvement, including a new central safety and quality office, a system-wide safety and quality governing board, a system-wide chief medical officer council, a system-wide infection control and antibiotic stewardship program, and a central PI and project management office.

"David brings to UC Davis broad experience and proven results in a major healthcare market," May said. "He has an impressive record of sound financial management and innovative practices for a high functioning health care system that has gained national attention. His success in raising funds to meet pressing needs, including for enhanced access to Medicaid and indigent patients, aligns well with our values at UC Davis Health."

Lubarsky has been recognized for his success in helping establish a centralized scheduling system, improving infrastructure, and improving performance across many areas of the University of Miami health system. He raised more than $100 million annually for the University of Miami from state and federal funding sources to aid enhanced access for Medicaid and indigent patients. Previously, as CEO of the 1,100-physician practice, he turned a $100 million loss into a $32 million surplus in one year by growing patient volumes and optimizing the revenue cycle while making sure already high patient experience scores were maintained. Of note, every one of his major initiatives has explicitly prioritized quality and empathetic patient care.

In his efforts to meet community needs, Lubarsky has worked with the state of Florida and Centers for Medicare & Medicaid Services to expand access to Medicaid, forging a close partnership with the other major academic centers in Florida in pursuit of this goal. He has also been working with Florida’s state and congressional representatives to expand existing graduate medical education programs that would best meet the state’s needs and to secure the necessary federal funding which has been frozen for more than 20 years.

For the last 16 years, Lubarsky has been chief of service of anesthesia and pain management for the largest safety net hospital in the U.S., Jackson Memorial Hospital. He served on their board overseeing safety and quality, and throughout his tenure has been a forceful advocate for a uniform high quality of care.

"It is a privilege to join this highly regarded, progressive and nationally recognized health system," Lubarsky said. "I look forward to working closely with the accomplished faculty and staff, and routinely interacting with Davis’ talented students and trainees. I have already heard many great ideas about how to catapult Davis to greater heights, and I hope to harness those ideas to catalyze innovation so that we better serve our patients, our local community and our academic mission."

UC Davis School of Medicine is one of the nation's leading medical schools, recognized for its research and primary-care programs. Ranked 34th in National Institutes of Health funding in 2013, it is designated as one of the nation’s inaugural Clinical Translational Science Centers.

A few highlights include:

  • A national reputation for life-changing biomedical discoveries
  • A passion for clinical care and a commitment to engaging people from underserved communities and advancing rural health
  • Fully accredited master’s degree programs in public health and in informatics
  • A combined M.D.-Ph.D. program that is training the next generation of physician-scientists to conduct high-impact research and translate discoveries into better clinical care

The Dean’s Departments and Offices include:

Additional departments:

To learn more, visit the medical school site.

UC Davis Medical Center, based in Sacramento, Calif., is a nationally renowned academic medical center where clinical practice, teaching and research converge to advance human health.

A few highlights:

  • A 627-bed multispecialty academic medical center
  • Serves 33 counties covering a 65,000-square-mile area north to the Oregon border and east to Nevada
  • Recognized as one of the “Most Wired” hospitals in the U.S.
  • Recognized by The Leapfrog Group as a “Top Hospital” for delivery of high-quality care
  • Ranked Sacramento's top hospital by U.S. News & World Report

Centers of excellence include:

  • UC Davis Comprehensive Cancer Center, one of only 41 National Cancer Institute-designated comprehensive centers nationwide
  • State-of-the-art emergency departments that include the region's only Level I adult and pediatric trauma centers
  • The internationally recognized UC Davis MIND Institute, devoted to finding treatments and cures for neurodevelopmental disorders
  • UC Davis Children's Hospital, a nationally ranked pediatric hospital with more than 120 physicians in 33 pediatric subspecialties
  • A pioneering telehealth program, which gives remote, underserved communities access to academic specialty and subspecialty care

To learn more, visit the medical center site.

The Betty Irene Moore School of Nursing at UC Davis cultivates academic excellence and addresses urgent, societal needs through leadership development, interprofessional education, transformative research, cultural inclusiveness and innovative technology. The school plays a critical role in preparing nurse leaders who will shape the future of health care and inform health policy.

The School of Nursing has five research focus areas: chronic disease management, health technology, pain management, Healthy People and Healthy Systems. Faculty come from a wide range of backgrounds including nursing, business administration, sociology, gerontology, medicine, information technology and psychology. School of Nursing students engage in classroom and clinical environments with students in the School of Medicine, health informatics and other health-related programs.

A few highlights include:

To learn more, visit the School of Nursing’s website.

The Practice Management Group (TPMG) represents all organized medical group practices of UC Davis Health System’s primary and specialty care faculty physicians. The group's purpose is to serve the health system’s missions through high-quality, cost-effective care delivery. By delegation from the Office of the Vice Chancellor and Dean, TPMG has shared responsibility for the clinical operations of the health system's professional practice activities.

The formation of TPMG is an important step in formalizing the leadership of the health system's medical group practices and in refining the role of its group practice in achieving the health system's research, teaching, patient care and community engagement goals. Its primary goal is to maintain a clinical practice that distinguishes UC Davis Health System as a leading faculty and academic health center.

Specific goals of TPMG include:

  • Increasing efficiency of practice and revenue
  • Decreasing practice expenses
  • Reducing silos and improving integration
  • Identifying areas to increase quality
  • Aligning incentives

David H. Wisner is the executive director of the Practice Management Group, overseeing faculty practice operations as well as the overall vision and strategic direction of TPMG and its day-to-day activities. Wisner collaborates with the leadership of the School of Medicine and medical center to set and achieve joint strategic goals across the health system.

More information



UC Davis stem cell researchers awarded $53 ...
Office of the Vice Chancellor and Dean | UC Davis Health

Welcome Dr. David Lubarsky to UC Davis Health!

David A. LubarskyUC Davis Chancellor Gary May has appointed David A. Lubarsky to the position of vice chancellor of human health sciences and chief executive officer of UC Davis Health, which includes the School of Medicine, the Betty Irene Moore School of Nursing, the 1,000-member physician practice group, and UC Davis Medical Center, a 627-bed acute-care hospital. Lubarsky will join UC Davis on July 2, 2018.

Lubarsky most recently served as the chief medical and systems integration officer with the University of Miami Health System, a position he has held since 2012. As a leader within the system, he has overseen the system’s four hospital and practice chief medical officers as well as patient safety and quality. In addition, he led the university’s self-insured malpractice program, which focuses on prevention, and patient and visitor services, including patient experience. During his tenure at the University of Miami, Lubarsky integrated programs to create system-wide consistent approaches to care and quality improvement, including a new central safety and quality office, a system-wide safety and quality governing board, a system-wide chief medical officer council, a system-wide infection control and antibiotic stewardship program, and a central PI and project management office.

"David brings to UC Davis broad experience and proven results in a major healthcare market," May said. "He has an impressive record of sound financial management and innovative practices for a high functioning health care system that has gained national attention. His success in raising funds to meet pressing needs, including for enhanced access to Medicaid and indigent patients, aligns well with our values at UC Davis Health."

Lubarsky has been recognized for his success in helping establish a centralized scheduling system, improving infrastructure, and improving performance across many areas of the University of Miami health system. He raised more than $100 million annually for the University of Miami from state and federal funding sources to aid enhanced access for Medicaid and indigent patients. Previously, as CEO of the 1,100-physician practice, he turned a $100 million loss into a $32 million surplus in one year by growing patient volumes and optimizing the revenue cycle while making sure already high patient experience scores were maintained. Of note, every one of his major initiatives has explicitly prioritized quality and empathetic patient care.

In his efforts to meet community needs, Lubarsky has worked with the state of Florida and Centers for Medicare & Medicaid Services to expand access to Medicaid, forging a close partnership with the other major academic centers in Florida in pursuit of this goal. He has also been working with Florida’s state and congressional representatives to expand existing graduate medical education programs that would best meet the state’s needs and to secure the necessary federal funding which has been frozen for more than 20 years.

For the last 16 years, Lubarsky has been chief of service of anesthesia and pain management for the largest safety net hospital in the U.S., Jackson Memorial Hospital. He served on their board overseeing safety and quality, and throughout his tenure has been a forceful advocate for a uniform high quality of care.

"It is a privilege to join this highly regarded, progressive and nationally recognized health system," Lubarsky said. "I look forward to working closely with the accomplished faculty and staff, and routinely interacting with Davis’ talented students and trainees. I have already heard many great ideas about how to catapult Davis to greater heights, and I hope to harness those ideas to catalyze innovation so that we better serve our patients, our local community and our academic mission."

UC Davis School of Medicine is one of the nation's leading medical schools, recognized for its research and primary-care programs. Ranked 34th in National Institutes of Health funding in 2013, it is designated as one of the nation’s inaugural Clinical Translational Science Centers.

A few highlights include:

  • A national reputation for life-changing biomedical discoveries
  • A passion for clinical care and a commitment to engaging people from underserved communities and advancing rural health
  • Fully accredited master’s degree programs in public health and in informatics
  • A combined M.D.-Ph.D. program that is training the next generation of physician-scientists to conduct high-impact research and translate discoveries into better clinical care

The Dean’s Departments and Offices include:

Additional departments:

To learn more, visit the medical school site.

UC Davis Medical Center, based in Sacramento, Calif., is a nationally renowned academic medical center where clinical practice, teaching and research converge to advance human health.

A few highlights:

  • A 627-bed multispecialty academic medical center
  • Serves 33 counties covering a 65,000-square-mile area north to the Oregon border and east to Nevada
  • Recognized as one of the “Most Wired” hospitals in the U.S.
  • Recognized by The Leapfrog Group as a “Top Hospital” for delivery of high-quality care
  • Ranked Sacramento's top hospital by U.S. News & World Report

Centers of excellence include:

  • UC Davis Comprehensive Cancer Center, one of only 41 National Cancer Institute-designated comprehensive centers nationwide
  • State-of-the-art emergency departments that include the region's only Level I adult and pediatric trauma centers
  • The internationally recognized UC Davis MIND Institute, devoted to finding treatments and cures for neurodevelopmental disorders
  • UC Davis Children's Hospital, a nationally ranked pediatric hospital with more than 120 physicians in 33 pediatric subspecialties
  • A pioneering telehealth program, which gives remote, underserved communities access to academic specialty and subspecialty care

To learn more, visit the medical center site.

The Betty Irene Moore School of Nursing at UC Davis cultivates academic excellence and addresses urgent, societal needs through leadership development, interprofessional education, transformative research, cultural inclusiveness and innovative technology. The school plays a critical role in preparing nurse leaders who will shape the future of health care and inform health policy.

The School of Nursing has five research focus areas: chronic disease management, health technology, pain management, Healthy People and Healthy Systems. Faculty come from a wide range of backgrounds including nursing, business administration, sociology, gerontology, medicine, information technology and psychology. School of Nursing students engage in classroom and clinical environments with students in the School of Medicine, health informatics and other health-related programs.

A few highlights include:

To learn more, visit the School of Nursing’s website.

The Practice Management Group (TPMG) represents all organized medical group practices of UC Davis Health System’s primary and specialty care faculty physicians. The group's purpose is to serve the health system’s missions through high-quality, cost-effective care delivery. By delegation from the Office of the Vice Chancellor and Dean, TPMG has shared responsibility for the clinical operations of the health system's professional practice activities.

The formation of TPMG is an important step in formalizing the leadership of the health system's medical group practices and in refining the role of its group practice in achieving the health system's research, teaching, patient care and community engagement goals. Its primary goal is to maintain a clinical practice that distinguishes UC Davis Health System as a leading faculty and academic health center.

Specific goals of TPMG include:

  • Increasing efficiency of practice and revenue
  • Decreasing practice expenses
  • Reducing silos and improving integration
  • Identifying areas to increase quality
  • Aligning incentives

David H. Wisner is the executive director of the Practice Management Group, overseeing faculty practice operations as well as the overall vision and strategic direction of TPMG and its day-to-day activities. Wisner collaborates with the leadership of the School of Medicine and medical center to set and achieve joint strategic goals across the health system.

More information



Office of the Vice Chancellor and Dean | UC Davis Health

Welcome Dr. David Lubarsky to UC Davis Health!

David A. LubarskyUC Davis Chancellor Gary May has appointed David A. Lubarsky to the position of vice chancellor of human health sciences and chief executive officer of UC Davis Health, which includes the School of Medicine, the Betty Irene Moore School of Nursing, the 1,000-member physician practice group, and UC Davis Medical Center, a 627-bed acute-care hospital. Lubarsky will join UC Davis on July 2, 2018.

Lubarsky most recently served as the chief medical and systems integration officer with the University of Miami Health System, a position he has held since 2012. As a leader within the system, he has overseen the system’s four hospital and practice chief medical officers as well as patient safety and quality. In addition, he led the university’s self-insured malpractice program, which focuses on prevention, and patient and visitor services, including patient experience. During his tenure at the University of Miami, Lubarsky integrated programs to create system-wide consistent approaches to care and quality improvement, including a new central safety and quality office, a system-wide safety and quality governing board, a system-wide chief medical officer council, a system-wide infection control and antibiotic stewardship program, and a central PI and project management office.

"David brings to UC Davis broad experience and proven results in a major healthcare market," May said. "He has an impressive record of sound financial management and innovative practices for a high functioning health care system that has gained national attention. His success in raising funds to meet pressing needs, including for enhanced access to Medicaid and indigent patients, aligns well with our values at UC Davis Health."

Lubarsky has been recognized for his success in helping establish a centralized scheduling system, improving infrastructure, and improving performance across many areas of the University of Miami health system. He raised more than $100 million annually for the University of Miami from state and federal funding sources to aid enhanced access for Medicaid and indigent patients. Previously, as CEO of the 1,100-physician practice, he turned a $100 million loss into a $32 million surplus in one year by growing patient volumes and optimizing the revenue cycle while making sure already high patient experience scores were maintained. Of note, every one of his major initiatives has explicitly prioritized quality and empathetic patient care.

In his efforts to meet community needs, Lubarsky has worked with the state of Florida and Centers for Medicare & Medicaid Services to expand access to Medicaid, forging a close partnership with the other major academic centers in Florida in pursuit of this goal. He has also been working with Florida’s state and congressional representatives to expand existing graduate medical education programs that would best meet the state’s needs and to secure the necessary federal funding which has been frozen for more than 20 years.

For the last 16 years, Lubarsky has been chief of service of anesthesia and pain management for the largest safety net hospital in the U.S., Jackson Memorial Hospital. He served on their board overseeing safety and quality, and throughout his tenure has been a forceful advocate for a uniform high quality of care.

"It is a privilege to join this highly regarded, progressive and nationally recognized health system," Lubarsky said. "I look forward to working closely with the accomplished faculty and staff, and routinely interacting with Davis’ talented students and trainees. I have already heard many great ideas about how to catapult Davis to greater heights, and I hope to harness those ideas to catalyze innovation so that we better serve our patients, our local community and our academic mission."

UC Davis School of Medicine is one of the nation's leading medical schools, recognized for its research and primary-care programs. Ranked 34th in National Institutes of Health funding in 2013, it is designated as one of the nation’s inaugural Clinical Translational Science Centers.

A few highlights include:

  • A national reputation for life-changing biomedical discoveries
  • A passion for clinical care and a commitment to engaging people from underserved communities and advancing rural health
  • Fully accredited master’s degree programs in public health and in informatics
  • A combined M.D.-Ph.D. program that is training the next generation of physician-scientists to conduct high-impact research and translate discoveries into better clinical care

The Dean’s Departments and Offices include:

Additional departments:

To learn more, visit the medical school site.

UC Davis Medical Center, based in Sacramento, Calif., is a nationally renowned academic medical center where clinical practice, teaching and research converge to advance human health.

A few highlights:

  • A 627-bed multispecialty academic medical center
  • Serves 33 counties covering a 65,000-square-mile area north to the Oregon border and east to Nevada
  • Recognized as one of the “Most Wired” hospitals in the U.S.
  • Recognized by The Leapfrog Group as a “Top Hospital” for delivery of high-quality care
  • Ranked Sacramento's top hospital by U.S. News & World Report

Centers of excellence include:

  • UC Davis Comprehensive Cancer Center, one of only 41 National Cancer Institute-designated comprehensive centers nationwide
  • State-of-the-art emergency departments that include the region's only Level I adult and pediatric trauma centers
  • The internationally recognized UC Davis MIND Institute, devoted to finding treatments and cures for neurodevelopmental disorders
  • UC Davis Children's Hospital, a nationally ranked pediatric hospital with more than 120 physicians in 33 pediatric subspecialties
  • A pioneering telehealth program, which gives remote, underserved communities access to academic specialty and subspecialty care

To learn more, visit the medical center site.

The Betty Irene Moore School of Nursing at UC Davis cultivates academic excellence and addresses urgent, societal needs through leadership development, interprofessional education, transformative research, cultural inclusiveness and innovative technology. The school plays a critical role in preparing nurse leaders who will shape the future of health care and inform health policy.

The School of Nursing has five research focus areas: chronic disease management, health technology, pain management, Healthy People and Healthy Systems. Faculty come from a wide range of backgrounds including nursing, business administration, sociology, gerontology, medicine, information technology and psychology. School of Nursing students engage in classroom and clinical environments with students in the School of Medicine, health informatics and other health-related programs.

A few highlights include:

To learn more, visit the School of Nursing’s website.

The Practice Management Group (TPMG) represents all organized medical group practices of UC Davis Health System’s primary and specialty care faculty physicians. The group's purpose is to serve the health system’s missions through high-quality, cost-effective care delivery. By delegation from the Office of the Vice Chancellor and Dean, TPMG has shared responsibility for the clinical operations of the health system's professional practice activities.

The formation of TPMG is an important step in formalizing the leadership of the health system's medical group practices and in refining the role of its group practice in achieving the health system's research, teaching, patient care and community engagement goals. Its primary goal is to maintain a clinical practice that distinguishes UC Davis Health System as a leading faculty and academic health center.

Specific goals of TPMG include:

  • Increasing efficiency of practice and revenue
  • Decreasing practice expenses
  • Reducing silos and improving integration
  • Identifying areas to increase quality
  • Aligning incentives

David H. Wisner is the executive director of the Practice Management Group, overseeing faculty practice operations as well as the overall vision and strategic direction of TPMG and its day-to-day activities. Wisner collaborates with the leadership of the School of Medicine and medical center to set and achieve joint strategic goals across the health system.

More information



NEWS | July 26, 2012

UC Davis stem cell researchers awarded $53 million

Funding supports work toward clinical trials to treat vascular disease, osteoporosis and Huntington's disease

(SACRAMENTO)

UC Davis Health System researchers who are working to speed therapies to patients suffering from critical limb ischemia, osteoporosis and Huntington's disease received approval today for three separate research grants from the state's stem cell agency totaling more than $53 million. Each of the research studies that can now begin at UC Davis are specifically designed to lead to U.S. Food and Drug Administration approval of human clinical trials using stem cells and regenerative therapies.

UC Davis team celebrates CIRM grant awards
UC Davis team celebrates CIRM grant awards

At today's meeting of the California Institute for Regenerative Medicine (CIRM) in San Francisco, the agency's 29-member governing board approved five other grant proposals as part of its $150 million Disease Team Research Awards program. Funding goes to a highly select group of scientific collaborations to accelerate the state's most promising stem cell research.

"Today's Disease Team awards reflect the expertise and experience that UC Davis brings to the world of regenerative medicine," said Jan Nolta, professor of internal medicine and director of the UC Davis Stem Cell Program and its Institute for Regenerative Cures in Sacramento. "Our teams are as eager as patients and families themselves to begin the type of clinical research that will allow us to discover new therapies and cures for people suffering from chronic and life-debilitating diseases. These generous grants allow our researchers to focus as never before on finding the best answers to the most challenging questions in regenerative medicine."

The three UC Davis grants that were funded "are breathtaking in their size, scope and potential," said Nolta.

Critical limb ischemia (CLI)
Armed with their new $14.1 million  CIRM grant, Nolta and John Laird, professor of cardiovascular medicine and director of the UC Davis Vascular Center, lead a team that plans to launch human clinical trials for critical limb ischemia, a vascular disease affecting about 2 million people around the country. The condition, which is often present in individuals with diabetes and severe peripheral artery disease, is caused by severe obstructions of the arteries, seriously decreasing blood flow to the feet and legs. It is associated with pain, debilitating foot ulcers, gangrene, and increased risk of leg amputation and death. Despite the best surgical revascularization efforts, at its end stages, this disease lacks effective therapies.

John Laird © UC Regents
John Laird

Bolstered by their recent preclinical studies in critical limb ischemia that showed stem cell safety and efficacy, Nolta and Laird plan to use mesenchymal stem cells from healthy bone marrow donors that are bioengineered to produce a revascularizing factor. The cells will be injected into the legs of CLI patients and are expected to migrate to oxygen-low areas in a patient's diseased limbs.  

"Our combination stem cell strategy is analogous to a paramedic vehicle that can deliver emergency care directly to a patient," said Laird, who has been investigating different stem cell approaches as possible vascular therapies for several years. "We've seen that the special growth factors produced by our engineered stem cells can rapidly restore blood flow in the limbs of animal models that had no leg circulation whatsoever. Our CIRM grant now enables us to completely focus on finalizing safety and efficacy tests for humans so we can move this candidate therapy into clinical trials that will hopefully save people from amputation."

Joining the UC Davis team in developing the novel mesenchymal stem cell therapeutic for CLI will be research partners at Reina Sofia University Hospital in Cordoba, Spain. The collaboration is a part of the Andalusian Initiative for Advanced Therapies, which was created by the regional government of Andalusia to sponsor non-commercial clinical trials in the field of cellular therapy.

Treatment for osteoporosis
Nancy Lane, professor of internal medicine, will use her $20 million  CIRM grant to lead her research team to optimize the use of a small molecule (LLP2A-Ale) to direct endogenous mesenchymal stem cells to the bone surface for the treatment of osteoporosis. The novel approach has the potential to promote new bone growth and provide an effective answer for men and postmenopausal women and who suffer from a disease that causes increased bone fragility and often leads to bone fractures and a significantly decreased quality of life.

Nancy Lane © UC Regents
Nancy Lane

Osteoporosis results from estrogen deficiencies and aging. It is the most common type of bone disease, and is expected to affect more than 61 million Americans by 2020. The disease occurs when the equilibrium between the formation of new bone and the reabsorption of old bone is disrupted in the body. In the U.S., 40 percent of women and 13 percent of men over the age of 50 will suffer an osteoporosis-related fracture in their lifetimes, with resulting pain and limitations on activity. Lane's proposal to CIRM noted that California has one of the nation's largest over-age-65 populations and can expect to experience greatly increased fracture rates because of the disease.

"The only currently approved therapy for osteoporosis that increases bone formation requires costly and inconvenient daily injections for two years," said Lane, who also serves as director of the UC Davis Musculoskeletal Diseases of Aging Research Group. "I'm very optimistic that with our Disease Team grant from CIRM, we will be able to successfully, and fairly quickly, develop a bone-building treatment of osteoporosis that only requires an occasional infusion."

In addition to research that will be done on UC Davis' Sacramento campus, Lane's CIRM grant represents economic-development opportunities for California businesses. It will contract with several companies to perform the crucial, preclinical studies that will ensure the small-molecule drug used to direct the bone-forming mesenchymal stem cells is safe. UC Davis will work with another company to synthesize and package the novel small-molecule compound for clinical trials. And yet another company will assist the university's disease team in working with FDA as the osteoporosis clinical trial gets under way, which is expected to occur in 2014.  These collaborations are valued at approximately $3.5 million per year over the next four years.

Huntington's disease (HD)
The research that will lead to clinical trials for Huntington's disease (HD) represents one of the most exciting developments in regenerative medicine. Armed with a new CIRM grant, Vicki Wheelock, clinical professor of neurology and director of the HDSA Center of Excellence at UC Davis, will be working with Nolta on a $19 million  push to launch the first FDA-approved cellular therapy for HD patients. Their plan is to infuse specially engineered mesenchymal stem cells into the brain tissue of Huntington's disease patients. The stem cells, which will be engineered to secrete brain-derived neurotrophic factor (BDNF), are designed to restore the health of brain cells damaged by the mutant Huntingtin (htt) protein that is the hallmark for the devastating neurodegenerative disease. This therapy has been shown to be effective in animal models of HD.

Vicki Wheelock © UC Regents
Vicki Wheelock

"About 1 in 10,000 Californians has Huntington's disease," said Wheelock. "It touches all races and socioeconomic levels. The financial burdens are in the billions, the emotional costs are immeasurable, and right now there is no cure. HD patients and family members have been tireless advocates for stem cell research. The CIRM grant enables us to work toward the first ever FDA-approved stem cell therapy for the disease. For physicians who have witnessed the tragedy of this illness over and over again, today we have hope for developing a disease-modifying treatment for HD and optimism for finding a cure."

Huntington's disease is an inherited disorder passed down through families in which brain cells waste away, or degenerate. While most patients develop symptoms as adults, children and teens can develop juvenile HD.  Movement, judgment, thinking and speech decline, and psychiatric symptoms are very disabling. Over the course of the disease, patients suffer painful involuntary movements and loss of independence. Many people who are at risk are reluctant to be tested for fear they may lose health insurance or their jobs, and families of HD victims face the added challenges and costs of long-term caregiving. 

The UC Davis trials for treating HD are targeted for earlier phases of the disease, when patients are younger and before the illness's full impact can take its toll. Wheelock said that mesenchymal stem cells represent remarkably effective delivery vehicles because they move well through tissue and can produce high levels of growth factor for uptake by the damaged neurons.

In preparation for a phase I clinical trial, the Huntington's disease team is carefully testing its proposed cellular infusion therapy for safety and effectiveness. In HD mouse models, the team has demonstrated that the delivery of brain-derived neurotrophic factors via mesenchymal stem cells significantly reduces behavioral deficits back to nearly normal levels.

"What's also exciting about our study is that our biological delivery system shows great promise for treating other neurodegenerative disorders such as amyotrophic lateral sclerosis (Lou Gehrig's disease), spinocerebellar ataxia, Alzheimer's disease, and even some forms of Parkinson's," said Wheelock. "Moreover, because HD patients have few other options, the benefit-to-risk ratio for our planned clinical trial is very high, and today's CIRM grant will enable us to move forward." 

The state's latest round of stem cell grants to UC Davis represent the largest single-day amount ever earmarked for regenerative medicine research at the university, and nearly equals the total amount of funding it has received from CIRM over the past six years.

"We know that one of CIRM's primary goals with its awards is to enable teams of laboratory scientists, clinicians and junior investigators to tackle the most clinically relevant treatment issues and overcome potential safety problems as early in the research process as possible," said Frederick J. Meyers, executive associate dean for UC Davis School of Medicine, who oversees the school's research, teaching, clinical care and community engagement. "We are honored to receive the agency's support."

Meyers emphasized the role many people, including donors, have played in expanding the stem cell research program at UC Davis.

"Along with talented teams and state grants, our research success also is the result of visionary private donors who have been catalysts for funding our scientists and projects that will have far-reaching benefits for improving human health," he said.

UC Davis is playing a leading role in regenerative medicine, with nearly 150 scientists working on a variety of stem cell-related research projects at campus locations in both Davis and Sacramento. The UC Davis Institute for Regenerative Cures, a facility supported by the California Institute for Regenerative Medicine (CIRM), opened in 2010 on the Sacramento campus. This $62 million facility is the university's hub for stem cell science. It includes Northern California's largest academic Good Manufacturing Practice laboratory, with state-of-the-art equipment and manufacturing rooms for cellular and gene therapies. UC Davis also has a Translational Human Embryonic Stem Cell Shared Research Facility in Davis and a collaborative partnership with the Institute for Pediatric Regenerative Medicine at Shriners Hospital for Children Northern California. All of the programs and facilities complement the university's Clinical and Translational Science Center, and focus on turning stem cells into cures. For more information, visit www.ucdmc.ucdavis.edu/stemcellresearch.

Office of the Vice Chancellor and Dean | UC Davis Health

Welcome Dr. David Lubarsky to UC Davis Health!

David A. LubarskyUC Davis Chancellor Gary May has appointed David A. Lubarsky to the position of vice chancellor of human health sciences and chief executive officer of UC Davis Health, which includes the School of Medicine, the Betty Irene Moore School of Nursing, the 1,000-member physician practice group, and UC Davis Medical Center, a 627-bed acute-care hospital. Lubarsky will join UC Davis on July 2, 2018.

Lubarsky most recently served as the chief medical and systems integration officer with the University of Miami Health System, a position he has held since 2012. As a leader within the system, he has overseen the system’s four hospital and practice chief medical officers as well as patient safety and quality. In addition, he led the university’s self-insured malpractice program, which focuses on prevention, and patient and visitor services, including patient experience. During his tenure at the University of Miami, Lubarsky integrated programs to create system-wide consistent approaches to care and quality improvement, including a new central safety and quality office, a system-wide safety and quality governing board, a system-wide chief medical officer council, a system-wide infection control and antibiotic stewardship program, and a central PI and project management office.

"David brings to UC Davis broad experience and proven results in a major healthcare market," May said. "He has an impressive record of sound financial management and innovative practices for a high functioning health care system that has gained national attention. His success in raising funds to meet pressing needs, including for enhanced access to Medicaid and indigent patients, aligns well with our values at UC Davis Health."

Lubarsky has been recognized for his success in helping establish a centralized scheduling system, improving infrastructure, and improving performance across many areas of the University of Miami health system. He raised more than $100 million annually for the University of Miami from state and federal funding sources to aid enhanced access for Medicaid and indigent patients. Previously, as CEO of the 1,100-physician practice, he turned a $100 million loss into a $32 million surplus in one year by growing patient volumes and optimizing the revenue cycle while making sure already high patient experience scores were maintained. Of note, every one of his major initiatives has explicitly prioritized quality and empathetic patient care.

In his efforts to meet community needs, Lubarsky has worked with the state of Florida and Centers for Medicare & Medicaid Services to expand access to Medicaid, forging a close partnership with the other major academic centers in Florida in pursuit of this goal. He has also been working with Florida’s state and congressional representatives to expand existing graduate medical education programs that would best meet the state’s needs and to secure the necessary federal funding which has been frozen for more than 20 years.

For the last 16 years, Lubarsky has been chief of service of anesthesia and pain management for the largest safety net hospital in the U.S., Jackson Memorial Hospital. He served on their board overseeing safety and quality, and throughout his tenure has been a forceful advocate for a uniform high quality of care.

"It is a privilege to join this highly regarded, progressive and nationally recognized health system," Lubarsky said. "I look forward to working closely with the accomplished faculty and staff, and routinely interacting with Davis’ talented students and trainees. I have already heard many great ideas about how to catapult Davis to greater heights, and I hope to harness those ideas to catalyze innovation so that we better serve our patients, our local community and our academic mission."

UC Davis School of Medicine is one of the nation's leading medical schools, recognized for its research and primary-care programs. Ranked 34th in National Institutes of Health funding in 2013, it is designated as one of the nation’s inaugural Clinical Translational Science Centers.

A few highlights include:

  • A national reputation for life-changing biomedical discoveries
  • A passion for clinical care and a commitment to engaging people from underserved communities and advancing rural health
  • Fully accredited master’s degree programs in public health and in informatics
  • A combined M.D.-Ph.D. program that is training the next generation of physician-scientists to conduct high-impact research and translate discoveries into better clinical care

The Dean’s Departments and Offices include:

Additional departments:

To learn more, visit the medical school site.

UC Davis Medical Center, based in Sacramento, Calif., is a nationally renowned academic medical center where clinical practice, teaching and research converge to advance human health.

A few highlights:

  • A 627-bed multispecialty academic medical center
  • Serves 33 counties covering a 65,000-square-mile area north to the Oregon border and east to Nevada
  • Recognized as one of the “Most Wired” hospitals in the U.S.
  • Recognized by The Leapfrog Group as a “Top Hospital” for delivery of high-quality care
  • Ranked Sacramento's top hospital by U.S. News & World Report

Centers of excellence include:

  • UC Davis Comprehensive Cancer Center, one of only 41 National Cancer Institute-designated comprehensive centers nationwide
  • State-of-the-art emergency departments that include the region's only Level I adult and pediatric trauma centers
  • The internationally recognized UC Davis MIND Institute, devoted to finding treatments and cures for neurodevelopmental disorders
  • UC Davis Children's Hospital, a nationally ranked pediatric hospital with more than 120 physicians in 33 pediatric subspecialties
  • A pioneering telehealth program, which gives remote, underserved communities access to academic specialty and subspecialty care

To learn more, visit the medical center site.

The Betty Irene Moore School of Nursing at UC Davis cultivates academic excellence and addresses urgent, societal needs through leadership development, interprofessional education, transformative research, cultural inclusiveness and innovative technology. The school plays a critical role in preparing nurse leaders who will shape the future of health care and inform health policy.

The School of Nursing has five research focus areas: chronic disease management, health technology, pain management, Healthy People and Healthy Systems. Faculty come from a wide range of backgrounds including nursing, business administration, sociology, gerontology, medicine, information technology and psychology. School of Nursing students engage in classroom and clinical environments with students in the School of Medicine, health informatics and other health-related programs.

A few highlights include:

To learn more, visit the School of Nursing’s website.

The Practice Management Group (TPMG) represents all organized medical group practices of UC Davis Health System’s primary and specialty care faculty physicians. The group's purpose is to serve the health system’s missions through high-quality, cost-effective care delivery. By delegation from the Office of the Vice Chancellor and Dean, TPMG has shared responsibility for the clinical operations of the health system's professional practice activities.

The formation of TPMG is an important step in formalizing the leadership of the health system's medical group practices and in refining the role of its group practice in achieving the health system's research, teaching, patient care and community engagement goals. Its primary goal is to maintain a clinical practice that distinguishes UC Davis Health System as a leading faculty and academic health center.

Specific goals of TPMG include:

  • Increasing efficiency of practice and revenue
  • Decreasing practice expenses
  • Reducing silos and improving integration
  • Identifying areas to increase quality
  • Aligning incentives

David H. Wisner is the executive director of the Practice Management Group, overseeing faculty practice operations as well as the overall vision and strategic direction of TPMG and its day-to-day activities. Wisner collaborates with the leadership of the School of Medicine and medical center to set and achieve joint strategic goals across the health system.

More information