Office of the Vice Chancellor and Dean | UC Davis Health

Welcome Dr. David Lubarsky to UC Davis Health!

David A. LubarskyUC Davis Chancellor Gary May has appointed David A. Lubarsky to the position of vice chancellor of human health sciences and chief executive officer of UC Davis Health, which includes the School of Medicine, the Betty Irene Moore School of Nursing, the 1,000-member physician practice group, and UC Davis Medical Center, a 627-bed acute-care hospital. Lubarsky will join UC Davis on July 2, 2018.

Lubarsky most recently served as the chief medical and systems integration officer with the University of Miami Health System, a position he has held since 2012. As a leader within the system, he has overseen the system’s four hospital and practice chief medical officers as well as patient safety and quality. In addition, he led the university’s self-insured malpractice program, which focuses on prevention, and patient and visitor services, including patient experience. During his tenure at the University of Miami, Lubarsky integrated programs to create system-wide consistent approaches to care and quality improvement, including a new central safety and quality office, a system-wide safety and quality governing board, a system-wide chief medical officer council, a system-wide infection control and antibiotic stewardship program, and a central PI and project management office.

"David brings to UC Davis broad experience and proven results in a major healthcare market," May said. "He has an impressive record of sound financial management and innovative practices for a high functioning health care system that has gained national attention. His success in raising funds to meet pressing needs, including for enhanced access to Medicaid and indigent patients, aligns well with our values at UC Davis Health."

Lubarsky has been recognized for his success in helping establish a centralized scheduling system, improving infrastructure, and improving performance across many areas of the University of Miami health system. He raised more than $100 million annually for the University of Miami from state and federal funding sources to aid enhanced access for Medicaid and indigent patients. Previously, as CEO of the 1,100-physician practice, he turned a $100 million loss into a $32 million surplus in one year by growing patient volumes and optimizing the revenue cycle while making sure already high patient experience scores were maintained. Of note, every one of his major initiatives has explicitly prioritized quality and empathetic patient care.

In his efforts to meet community needs, Lubarsky has worked with the state of Florida and Centers for Medicare & Medicaid Services to expand access to Medicaid, forging a close partnership with the other major academic centers in Florida in pursuit of this goal. He has also been working with Florida’s state and congressional representatives to expand existing graduate medical education programs that would best meet the state’s needs and to secure the necessary federal funding which has been frozen for more than 20 years.

For the last 16 years, Lubarsky has been chief of service of anesthesia and pain management for the largest safety net hospital in the U.S., Jackson Memorial Hospital. He served on their board overseeing safety and quality, and throughout his tenure has been a forceful advocate for a uniform high quality of care.

"It is a privilege to join this highly regarded, progressive and nationally recognized health system," Lubarsky said. "I look forward to working closely with the accomplished faculty and staff, and routinely interacting with Davis’ talented students and trainees. I have already heard many great ideas about how to catapult Davis to greater heights, and I hope to harness those ideas to catalyze innovation so that we better serve our patients, our local community and our academic mission."

UC Davis School of Medicine is one of the nation's leading medical schools, recognized for its research and primary-care programs. Ranked 34th in National Institutes of Health funding in 2013, it is designated as one of the nation’s inaugural Clinical Translational Science Centers.

A few highlights include:

  • A national reputation for life-changing biomedical discoveries
  • A passion for clinical care and a commitment to engaging people from underserved communities and advancing rural health
  • Fully accredited master’s degree programs in public health and in informatics
  • A combined M.D.-Ph.D. program that is training the next generation of physician-scientists to conduct high-impact research and translate discoveries into better clinical care

The Dean’s Departments and Offices include:

Additional departments:

To learn more, visit the medical school site.

UC Davis Medical Center, based in Sacramento, Calif., is a nationally renowned academic medical center where clinical practice, teaching and research converge to advance human health.

A few highlights:

  • A 627-bed multispecialty academic medical center
  • Serves 33 counties covering a 65,000-square-mile area north to the Oregon border and east to Nevada
  • Recognized as one of the “Most Wired” hospitals in the U.S.
  • Recognized by The Leapfrog Group as a “Top Hospital” for delivery of high-quality care
  • Ranked Sacramento's top hospital by U.S. News & World Report

Centers of excellence include:

  • UC Davis Comprehensive Cancer Center, one of only 41 National Cancer Institute-designated comprehensive centers nationwide
  • State-of-the-art emergency departments that include the region's only Level I adult and pediatric trauma centers
  • The internationally recognized UC Davis MIND Institute, devoted to finding treatments and cures for neurodevelopmental disorders
  • UC Davis Children's Hospital, a nationally ranked pediatric hospital with more than 120 physicians in 33 pediatric subspecialties
  • A pioneering telehealth program, which gives remote, underserved communities access to academic specialty and subspecialty care

To learn more, visit the medical center site.

The Betty Irene Moore School of Nursing at UC Davis cultivates academic excellence and addresses urgent, societal needs through leadership development, interprofessional education, transformative research, cultural inclusiveness and innovative technology. The school plays a critical role in preparing nurse leaders who will shape the future of health care and inform health policy.

The School of Nursing has five research focus areas: chronic disease management, health technology, pain management, Healthy People and Healthy Systems. Faculty come from a wide range of backgrounds including nursing, business administration, sociology, gerontology, medicine, information technology and psychology. School of Nursing students engage in classroom and clinical environments with students in the School of Medicine, health informatics and other health-related programs.

A few highlights include:

To learn more, visit the School of Nursing’s website.

The Practice Management Group (TPMG) represents all organized medical group practices of UC Davis Health System’s primary and specialty care faculty physicians. The group's purpose is to serve the health system’s missions through high-quality, cost-effective care delivery. By delegation from the Office of the Vice Chancellor and Dean, TPMG has shared responsibility for the clinical operations of the health system's professional practice activities.

The formation of TPMG is an important step in formalizing the leadership of the health system's medical group practices and in refining the role of its group practice in achieving the health system's research, teaching, patient care and community engagement goals. Its primary goal is to maintain a clinical practice that distinguishes UC Davis Health System as a leading faculty and academic health center.

Specific goals of TPMG include:

  • Increasing efficiency of practice and revenue
  • Decreasing practice expenses
  • Reducing silos and improving integration
  • Identifying areas to increase quality
  • Aligning incentives

David H. Wisner is the executive director of the Practice Management Group, overseeing faculty practice operations as well as the overall vision and strategic direction of TPMG and its day-to-day activities. Wisner collaborates with the leadership of the School of Medicine and medical center to set and achieve joint strategic goals across the health system.

More information



Office of the Vice Chancellor and Dean | UC Davis Health

Welcome Dr. David Lubarsky to UC Davis Health!

David A. LubarskyUC Davis Chancellor Gary May has appointed David A. Lubarsky to the position of vice chancellor of human health sciences and chief executive officer of UC Davis Health, which includes the School of Medicine, the Betty Irene Moore School of Nursing, the 1,000-member physician practice group, and UC Davis Medical Center, a 627-bed acute-care hospital. Lubarsky will join UC Davis on July 2, 2018.

Lubarsky most recently served as the chief medical and systems integration officer with the University of Miami Health System, a position he has held since 2012. As a leader within the system, he has overseen the system’s four hospital and practice chief medical officers as well as patient safety and quality. In addition, he led the university’s self-insured malpractice program, which focuses on prevention, and patient and visitor services, including patient experience. During his tenure at the University of Miami, Lubarsky integrated programs to create system-wide consistent approaches to care and quality improvement, including a new central safety and quality office, a system-wide safety and quality governing board, a system-wide chief medical officer council, a system-wide infection control and antibiotic stewardship program, and a central PI and project management office.

"David brings to UC Davis broad experience and proven results in a major healthcare market," May said. "He has an impressive record of sound financial management and innovative practices for a high functioning health care system that has gained national attention. His success in raising funds to meet pressing needs, including for enhanced access to Medicaid and indigent patients, aligns well with our values at UC Davis Health."

Lubarsky has been recognized for his success in helping establish a centralized scheduling system, improving infrastructure, and improving performance across many areas of the University of Miami health system. He raised more than $100 million annually for the University of Miami from state and federal funding sources to aid enhanced access for Medicaid and indigent patients. Previously, as CEO of the 1,100-physician practice, he turned a $100 million loss into a $32 million surplus in one year by growing patient volumes and optimizing the revenue cycle while making sure already high patient experience scores were maintained. Of note, every one of his major initiatives has explicitly prioritized quality and empathetic patient care.

In his efforts to meet community needs, Lubarsky has worked with the state of Florida and Centers for Medicare & Medicaid Services to expand access to Medicaid, forging a close partnership with the other major academic centers in Florida in pursuit of this goal. He has also been working with Florida’s state and congressional representatives to expand existing graduate medical education programs that would best meet the state’s needs and to secure the necessary federal funding which has been frozen for more than 20 years.

For the last 16 years, Lubarsky has been chief of service of anesthesia and pain management for the largest safety net hospital in the U.S., Jackson Memorial Hospital. He served on their board overseeing safety and quality, and throughout his tenure has been a forceful advocate for a uniform high quality of care.

"It is a privilege to join this highly regarded, progressive and nationally recognized health system," Lubarsky said. "I look forward to working closely with the accomplished faculty and staff, and routinely interacting with Davis’ talented students and trainees. I have already heard many great ideas about how to catapult Davis to greater heights, and I hope to harness those ideas to catalyze innovation so that we better serve our patients, our local community and our academic mission."

UC Davis School of Medicine is one of the nation's leading medical schools, recognized for its research and primary-care programs. Ranked 34th in National Institutes of Health funding in 2013, it is designated as one of the nation’s inaugural Clinical Translational Science Centers.

A few highlights include:

  • A national reputation for life-changing biomedical discoveries
  • A passion for clinical care and a commitment to engaging people from underserved communities and advancing rural health
  • Fully accredited master’s degree programs in public health and in informatics
  • A combined M.D.-Ph.D. program that is training the next generation of physician-scientists to conduct high-impact research and translate discoveries into better clinical care

The Dean’s Departments and Offices include:

Additional departments:

To learn more, visit the medical school site.

UC Davis Medical Center, based in Sacramento, Calif., is a nationally renowned academic medical center where clinical practice, teaching and research converge to advance human health.

A few highlights:

  • A 627-bed multispecialty academic medical center
  • Serves 33 counties covering a 65,000-square-mile area north to the Oregon border and east to Nevada
  • Recognized as one of the “Most Wired” hospitals in the U.S.
  • Recognized by The Leapfrog Group as a “Top Hospital” for delivery of high-quality care
  • Ranked Sacramento's top hospital by U.S. News & World Report

Centers of excellence include:

  • UC Davis Comprehensive Cancer Center, one of only 41 National Cancer Institute-designated comprehensive centers nationwide
  • State-of-the-art emergency departments that include the region's only Level I adult and pediatric trauma centers
  • The internationally recognized UC Davis MIND Institute, devoted to finding treatments and cures for neurodevelopmental disorders
  • UC Davis Children's Hospital, a nationally ranked pediatric hospital with more than 120 physicians in 33 pediatric subspecialties
  • A pioneering telehealth program, which gives remote, underserved communities access to academic specialty and subspecialty care

To learn more, visit the medical center site.

The Betty Irene Moore School of Nursing at UC Davis cultivates academic excellence and addresses urgent, societal needs through leadership development, interprofessional education, transformative research, cultural inclusiveness and innovative technology. The school plays a critical role in preparing nurse leaders who will shape the future of health care and inform health policy.

The School of Nursing has five research focus areas: chronic disease management, health technology, pain management, Healthy People and Healthy Systems. Faculty come from a wide range of backgrounds including nursing, business administration, sociology, gerontology, medicine, information technology and psychology. School of Nursing students engage in classroom and clinical environments with students in the School of Medicine, health informatics and other health-related programs.

A few highlights include:

To learn more, visit the School of Nursing’s website.

The Practice Management Group (TPMG) represents all organized medical group practices of UC Davis Health System’s primary and specialty care faculty physicians. The group's purpose is to serve the health system’s missions through high-quality, cost-effective care delivery. By delegation from the Office of the Vice Chancellor and Dean, TPMG has shared responsibility for the clinical operations of the health system's professional practice activities.

The formation of TPMG is an important step in formalizing the leadership of the health system's medical group practices and in refining the role of its group practice in achieving the health system's research, teaching, patient care and community engagement goals. Its primary goal is to maintain a clinical practice that distinguishes UC Davis Health System as a leading faculty and academic health center.

Specific goals of TPMG include:

  • Increasing efficiency of practice and revenue
  • Decreasing practice expenses
  • Reducing silos and improving integration
  • Identifying areas to increase quality
  • Aligning incentives

David H. Wisner is the executive director of the Practice Management Group, overseeing faculty practice operations as well as the overall vision and strategic direction of TPMG and its day-to-day activities. Wisner collaborates with the leadership of the School of Medicine and medical center to set and achieve joint strategic goals across the health system.

More information



UC Davis investigators develop method of directing stem ...
Office of the Vice Chancellor and Dean | UC Davis Health

Welcome Dr. David Lubarsky to UC Davis Health!

David A. LubarskyUC Davis Chancellor Gary May has appointed David A. Lubarsky to the position of vice chancellor of human health sciences and chief executive officer of UC Davis Health, which includes the School of Medicine, the Betty Irene Moore School of Nursing, the 1,000-member physician practice group, and UC Davis Medical Center, a 627-bed acute-care hospital. Lubarsky will join UC Davis on July 2, 2018.

Lubarsky most recently served as the chief medical and systems integration officer with the University of Miami Health System, a position he has held since 2012. As a leader within the system, he has overseen the system’s four hospital and practice chief medical officers as well as patient safety and quality. In addition, he led the university’s self-insured malpractice program, which focuses on prevention, and patient and visitor services, including patient experience. During his tenure at the University of Miami, Lubarsky integrated programs to create system-wide consistent approaches to care and quality improvement, including a new central safety and quality office, a system-wide safety and quality governing board, a system-wide chief medical officer council, a system-wide infection control and antibiotic stewardship program, and a central PI and project management office.

"David brings to UC Davis broad experience and proven results in a major healthcare market," May said. "He has an impressive record of sound financial management and innovative practices for a high functioning health care system that has gained national attention. His success in raising funds to meet pressing needs, including for enhanced access to Medicaid and indigent patients, aligns well with our values at UC Davis Health."

Lubarsky has been recognized for his success in helping establish a centralized scheduling system, improving infrastructure, and improving performance across many areas of the University of Miami health system. He raised more than $100 million annually for the University of Miami from state and federal funding sources to aid enhanced access for Medicaid and indigent patients. Previously, as CEO of the 1,100-physician practice, he turned a $100 million loss into a $32 million surplus in one year by growing patient volumes and optimizing the revenue cycle while making sure already high patient experience scores were maintained. Of note, every one of his major initiatives has explicitly prioritized quality and empathetic patient care.

In his efforts to meet community needs, Lubarsky has worked with the state of Florida and Centers for Medicare & Medicaid Services to expand access to Medicaid, forging a close partnership with the other major academic centers in Florida in pursuit of this goal. He has also been working with Florida’s state and congressional representatives to expand existing graduate medical education programs that would best meet the state’s needs and to secure the necessary federal funding which has been frozen for more than 20 years.

For the last 16 years, Lubarsky has been chief of service of anesthesia and pain management for the largest safety net hospital in the U.S., Jackson Memorial Hospital. He served on their board overseeing safety and quality, and throughout his tenure has been a forceful advocate for a uniform high quality of care.

"It is a privilege to join this highly regarded, progressive and nationally recognized health system," Lubarsky said. "I look forward to working closely with the accomplished faculty and staff, and routinely interacting with Davis’ talented students and trainees. I have already heard many great ideas about how to catapult Davis to greater heights, and I hope to harness those ideas to catalyze innovation so that we better serve our patients, our local community and our academic mission."

UC Davis School of Medicine is one of the nation's leading medical schools, recognized for its research and primary-care programs. Ranked 34th in National Institutes of Health funding in 2013, it is designated as one of the nation’s inaugural Clinical Translational Science Centers.

A few highlights include:

  • A national reputation for life-changing biomedical discoveries
  • A passion for clinical care and a commitment to engaging people from underserved communities and advancing rural health
  • Fully accredited master’s degree programs in public health and in informatics
  • A combined M.D.-Ph.D. program that is training the next generation of physician-scientists to conduct high-impact research and translate discoveries into better clinical care

The Dean’s Departments and Offices include:

Additional departments:

To learn more, visit the medical school site.

UC Davis Medical Center, based in Sacramento, Calif., is a nationally renowned academic medical center where clinical practice, teaching and research converge to advance human health.

A few highlights:

  • A 627-bed multispecialty academic medical center
  • Serves 33 counties covering a 65,000-square-mile area north to the Oregon border and east to Nevada
  • Recognized as one of the “Most Wired” hospitals in the U.S.
  • Recognized by The Leapfrog Group as a “Top Hospital” for delivery of high-quality care
  • Ranked Sacramento's top hospital by U.S. News & World Report

Centers of excellence include:

  • UC Davis Comprehensive Cancer Center, one of only 41 National Cancer Institute-designated comprehensive centers nationwide
  • State-of-the-art emergency departments that include the region's only Level I adult and pediatric trauma centers
  • The internationally recognized UC Davis MIND Institute, devoted to finding treatments and cures for neurodevelopmental disorders
  • UC Davis Children's Hospital, a nationally ranked pediatric hospital with more than 120 physicians in 33 pediatric subspecialties
  • A pioneering telehealth program, which gives remote, underserved communities access to academic specialty and subspecialty care

To learn more, visit the medical center site.

The Betty Irene Moore School of Nursing at UC Davis cultivates academic excellence and addresses urgent, societal needs through leadership development, interprofessional education, transformative research, cultural inclusiveness and innovative technology. The school plays a critical role in preparing nurse leaders who will shape the future of health care and inform health policy.

The School of Nursing has five research focus areas: chronic disease management, health technology, pain management, Healthy People and Healthy Systems. Faculty come from a wide range of backgrounds including nursing, business administration, sociology, gerontology, medicine, information technology and psychology. School of Nursing students engage in classroom and clinical environments with students in the School of Medicine, health informatics and other health-related programs.

A few highlights include:

To learn more, visit the School of Nursing’s website.

The Practice Management Group (TPMG) represents all organized medical group practices of UC Davis Health System’s primary and specialty care faculty physicians. The group's purpose is to serve the health system’s missions through high-quality, cost-effective care delivery. By delegation from the Office of the Vice Chancellor and Dean, TPMG has shared responsibility for the clinical operations of the health system's professional practice activities.

The formation of TPMG is an important step in formalizing the leadership of the health system's medical group practices and in refining the role of its group practice in achieving the health system's research, teaching, patient care and community engagement goals. Its primary goal is to maintain a clinical practice that distinguishes UC Davis Health System as a leading faculty and academic health center.

Specific goals of TPMG include:

  • Increasing efficiency of practice and revenue
  • Decreasing practice expenses
  • Reducing silos and improving integration
  • Identifying areas to increase quality
  • Aligning incentives

David H. Wisner is the executive director of the Practice Management Group, overseeing faculty practice operations as well as the overall vision and strategic direction of TPMG and its day-to-day activities. Wisner collaborates with the leadership of the School of Medicine and medical center to set and achieve joint strategic goals across the health system.

More information



Office of the Vice Chancellor and Dean | UC Davis Health

Welcome Dr. David Lubarsky to UC Davis Health!

David A. LubarskyUC Davis Chancellor Gary May has appointed David A. Lubarsky to the position of vice chancellor of human health sciences and chief executive officer of UC Davis Health, which includes the School of Medicine, the Betty Irene Moore School of Nursing, the 1,000-member physician practice group, and UC Davis Medical Center, a 627-bed acute-care hospital. Lubarsky will join UC Davis on July 2, 2018.

Lubarsky most recently served as the chief medical and systems integration officer with the University of Miami Health System, a position he has held since 2012. As a leader within the system, he has overseen the system’s four hospital and practice chief medical officers as well as patient safety and quality. In addition, he led the university’s self-insured malpractice program, which focuses on prevention, and patient and visitor services, including patient experience. During his tenure at the University of Miami, Lubarsky integrated programs to create system-wide consistent approaches to care and quality improvement, including a new central safety and quality office, a system-wide safety and quality governing board, a system-wide chief medical officer council, a system-wide infection control and antibiotic stewardship program, and a central PI and project management office.

"David brings to UC Davis broad experience and proven results in a major healthcare market," May said. "He has an impressive record of sound financial management and innovative practices for a high functioning health care system that has gained national attention. His success in raising funds to meet pressing needs, including for enhanced access to Medicaid and indigent patients, aligns well with our values at UC Davis Health."

Lubarsky has been recognized for his success in helping establish a centralized scheduling system, improving infrastructure, and improving performance across many areas of the University of Miami health system. He raised more than $100 million annually for the University of Miami from state and federal funding sources to aid enhanced access for Medicaid and indigent patients. Previously, as CEO of the 1,100-physician practice, he turned a $100 million loss into a $32 million surplus in one year by growing patient volumes and optimizing the revenue cycle while making sure already high patient experience scores were maintained. Of note, every one of his major initiatives has explicitly prioritized quality and empathetic patient care.

In his efforts to meet community needs, Lubarsky has worked with the state of Florida and Centers for Medicare & Medicaid Services to expand access to Medicaid, forging a close partnership with the other major academic centers in Florida in pursuit of this goal. He has also been working with Florida’s state and congressional representatives to expand existing graduate medical education programs that would best meet the state’s needs and to secure the necessary federal funding which has been frozen for more than 20 years.

For the last 16 years, Lubarsky has been chief of service of anesthesia and pain management for the largest safety net hospital in the U.S., Jackson Memorial Hospital. He served on their board overseeing safety and quality, and throughout his tenure has been a forceful advocate for a uniform high quality of care.

"It is a privilege to join this highly regarded, progressive and nationally recognized health system," Lubarsky said. "I look forward to working closely with the accomplished faculty and staff, and routinely interacting with Davis’ talented students and trainees. I have already heard many great ideas about how to catapult Davis to greater heights, and I hope to harness those ideas to catalyze innovation so that we better serve our patients, our local community and our academic mission."

UC Davis School of Medicine is one of the nation's leading medical schools, recognized for its research and primary-care programs. Ranked 34th in National Institutes of Health funding in 2013, it is designated as one of the nation’s inaugural Clinical Translational Science Centers.

A few highlights include:

  • A national reputation for life-changing biomedical discoveries
  • A passion for clinical care and a commitment to engaging people from underserved communities and advancing rural health
  • Fully accredited master’s degree programs in public health and in informatics
  • A combined M.D.-Ph.D. program that is training the next generation of physician-scientists to conduct high-impact research and translate discoveries into better clinical care

The Dean’s Departments and Offices include:

Additional departments:

To learn more, visit the medical school site.

UC Davis Medical Center, based in Sacramento, Calif., is a nationally renowned academic medical center where clinical practice, teaching and research converge to advance human health.

A few highlights:

  • A 627-bed multispecialty academic medical center
  • Serves 33 counties covering a 65,000-square-mile area north to the Oregon border and east to Nevada
  • Recognized as one of the “Most Wired” hospitals in the U.S.
  • Recognized by The Leapfrog Group as a “Top Hospital” for delivery of high-quality care
  • Ranked Sacramento's top hospital by U.S. News & World Report

Centers of excellence include:

  • UC Davis Comprehensive Cancer Center, one of only 41 National Cancer Institute-designated comprehensive centers nationwide
  • State-of-the-art emergency departments that include the region's only Level I adult and pediatric trauma centers
  • The internationally recognized UC Davis MIND Institute, devoted to finding treatments and cures for neurodevelopmental disorders
  • UC Davis Children's Hospital, a nationally ranked pediatric hospital with more than 120 physicians in 33 pediatric subspecialties
  • A pioneering telehealth program, which gives remote, underserved communities access to academic specialty and subspecialty care

To learn more, visit the medical center site.

The Betty Irene Moore School of Nursing at UC Davis cultivates academic excellence and addresses urgent, societal needs through leadership development, interprofessional education, transformative research, cultural inclusiveness and innovative technology. The school plays a critical role in preparing nurse leaders who will shape the future of health care and inform health policy.

The School of Nursing has five research focus areas: chronic disease management, health technology, pain management, Healthy People and Healthy Systems. Faculty come from a wide range of backgrounds including nursing, business administration, sociology, gerontology, medicine, information technology and psychology. School of Nursing students engage in classroom and clinical environments with students in the School of Medicine, health informatics and other health-related programs.

A few highlights include:

To learn more, visit the School of Nursing’s website.

The Practice Management Group (TPMG) represents all organized medical group practices of UC Davis Health System’s primary and specialty care faculty physicians. The group's purpose is to serve the health system’s missions through high-quality, cost-effective care delivery. By delegation from the Office of the Vice Chancellor and Dean, TPMG has shared responsibility for the clinical operations of the health system's professional practice activities.

The formation of TPMG is an important step in formalizing the leadership of the health system's medical group practices and in refining the role of its group practice in achieving the health system's research, teaching, patient care and community engagement goals. Its primary goal is to maintain a clinical practice that distinguishes UC Davis Health System as a leading faculty and academic health center.

Specific goals of TPMG include:

  • Increasing efficiency of practice and revenue
  • Decreasing practice expenses
  • Reducing silos and improving integration
  • Identifying areas to increase quality
  • Aligning incentives

David H. Wisner is the executive director of the Practice Management Group, overseeing faculty practice operations as well as the overall vision and strategic direction of TPMG and its day-to-day activities. Wisner collaborates with the leadership of the School of Medicine and medical center to set and achieve joint strategic goals across the health system.

More information



NEWS | February 6, 2012

UC Davis investigators develop method of directing stem cells to increase bone formation and bone strength

Successful testing in mice paves the way toward human trials for patients with osteoporosis

(SACRAMENTO)

A research team led by UC Davis Health System scientists has developed a novel technique to enhance bone growth by using a molecule which, when injected into the bloodstream, directs the body's stem cells to travel to the surface of bones. Once these cells are guided to the bone surface by this molecule, the stem cells differentiate into bone-forming cells and synthesize proteins to enhance bone growth. The study, which was published online today in Nature Medicine, used a mouse model of osteoporosis to demonstrate a unique treatment approach that increases bone density and prevents bone loss associated with aging and estrogen deficiency.

Wei Yao and Nancy Lane © UC Regents
Researchers Wei Yao (left) and Nancy Lane (right)

"There are many stem cells, even in elderly people, but they do not readily migrate to bone," said Wei Yao, the principal investigator and lead author of the study. "Finding a molecule that attaches to stem cells and guides them to the targets we need is a real breakthrough."

Researchers are exploring stem cells as possible treatments for a wide variety of conditions and injuries, ranging from peripheral artery disease and macular degeneration to blood disorders, skin wounds and diseased organs. Directing stem cells to travel and adhere to the surface of bone for bone formation has been among the elusive goals in regenerative medicine.

The researchers made use of a unique hybrid molecule, LLP2A-alendronate, developed by a research team led by Kit Lam, professor and chair of the UC Davis Department of Biochemistry and Molecular Medicine. The researchers' hybrid molecule consists of two parts: the LLP2A part that attaches to mesenchymal stem cells in the bone marrow, and a second part that consists of the bone-homing drug alendronate. After the hybrid molecule was injected into the bloodstream, it picked up mesenchymal stem cells in the bone marrow and directed those cells to the surfaces of bone, where the stem cells carried out their natural bone-formation and repair functions.

"Our study confirms that stem-cell-binding molecules can be exploited to direct stem cells to therapeutic sites inside an animal," said Lam, who also is an author of the article. "It represents a very important step in making this type of stem cell therapy a reality."

Twelve weeks after the hybrid molecule was injected into mice, bone mass in the femur (thigh bone) and vertebrae (in the spine) increased and bone strength improved compared to control mice who did not receive the hybrid molecule. Treated mice that were normally of an age when bone loss would occur also had improved bone formation, as did those that were models for menopause.

Kit Lam © UC Regents
Kit Lam

Alendronate, also known by the brand name Fosamax, is commonly taken by women with osteoporosis to reduce the risk of fracture. The research team incorporated alendronate into the hybrid molecules because once in the bloodstream, it goes directly to the bone surface, where it slows the rate of bone breakdown.  According to Nancy Lane, a co-investigator on the study and director of the UC Davis Musculoskeletal Diseases of Aging Research Group, the dose of alendronate in the hybrid compound was low and unlikely to have inhibited the compound's therapeutic effect.

"For the first time, we may have potentially found a way to direct a person's own stem cells to the bone surface where they can regenerate bone," said Lane, who is an Endowed Professor of Medicine and Rheumatology and an expert on osteoporosis. "This technique could become a revolutionary new therapy for osteoporosis as well as for other conditions that require new bone formation."

Osteoporosis is a major public health problem for 44 million Americans. One in two women will suffer a fracture due to osteoporosis in their lifetime. Although effective medications are available to help prevent fracture risk, including alendronate, their use is limited by potential harmful effects of long-term use.

The major causes for osteoporosis in women include estrogen deficiency, aging and steroid excess from treatment of chronic inflammatory conditions such as rheumatoid arthritis. Generally, the osteoporosis generated by these metabolic conditions results from change in the bone remodeling cycle that weakens the bone's architecture and increases fracture risk.

Mesenchymal stem cells from bone marrow induce new bone remodeling, which thicken and strengthen bone.

The authors noted that the potential use of this stem cell therapy is not limited to treating osteoporosis. They said it may prove invaluable for other disorders and conditions that could benefit from enhanced bone rebuilding, such as bone fractures, bone infections or cancer treatments. 

Jan Nolta © UC Regents
Jan Nolta

"These results are very promising for translating into human therapy," said Jan Nolta, professor of internal medicine, an author of the study and director of the UC Davis Institute for Regenerative Cures. "We have shown this potential therapy is effective in rodents, and our goal now is to move it into clinical trials."

Funding for the study came from the Endowment on Healthy Aging and the National Institutes of Health. The California Institute for Regenerative Medicine has given the team a planning grant to develop a proposal for human clinical trials.

"This research was a collaboration of stem cell biologists, biochemists, translational scientists, a bone biologist and clinicians," said Lane. "It was a truly fruitful team effort with remarkable results."

The Nature Medicine article is titled "Directing mesenchymal stem cells to bone to augment bone formation and increase bone mass." Min Guan, who is affiliated with the UC Davis Department of Internal Medicine, was co-lead author of the paper. Other UC Davis authors were Ruiwu Liu, Junjing Jia, Liping Meng, Ping Zhou and Mohammad Shahnazari, from the departments of Internal Medicine, and Biochemistry and Molecular Medicine, as well as the UC Davis Institute for Regenerative Cures. Authors Brian Panganiban and Robert O. Ritchie are with the Department of Materials Science and Engineering at UC Berkeley.

UC Davis is playing a leading role in regenerative medicine, with nearly 150 scientists working on a variety of stem cell-related research projects at campus locations in both Davis and Sacramento. The UC Davis Institute for Regenerative Cures, a facility supported by the California Institute for Regenerative Medicine (CIRM), opened in 2010 on the Sacramento campus. This $62 million facility is the university's hub for stem cell science. It includes Northern California's largest academic Good Manufacturing Practice laboratory, with state-of-the-art equipment and manufacturing rooms for cellular and gene therapies. UC Davis also has a Translational Human Embryonic Stem Cell Shared Research Facility in Davis and a collaborative partnership with the Institute for Pediatric Regenerative Medicine at Shriners Hospital for Children Northern California. All of the programs and facilities complement the university's Clinical and Translational Science Center, and focus on turning stem cells into cures. For more information, visit www.ucdmc.ucdavis.edu/stemcellresearch.

Office of the Vice Chancellor and Dean | UC Davis Health

Welcome Dr. David Lubarsky to UC Davis Health!

David A. LubarskyUC Davis Chancellor Gary May has appointed David A. Lubarsky to the position of vice chancellor of human health sciences and chief executive officer of UC Davis Health, which includes the School of Medicine, the Betty Irene Moore School of Nursing, the 1,000-member physician practice group, and UC Davis Medical Center, a 627-bed acute-care hospital. Lubarsky will join UC Davis on July 2, 2018.

Lubarsky most recently served as the chief medical and systems integration officer with the University of Miami Health System, a position he has held since 2012. As a leader within the system, he has overseen the system’s four hospital and practice chief medical officers as well as patient safety and quality. In addition, he led the university’s self-insured malpractice program, which focuses on prevention, and patient and visitor services, including patient experience. During his tenure at the University of Miami, Lubarsky integrated programs to create system-wide consistent approaches to care and quality improvement, including a new central safety and quality office, a system-wide safety and quality governing board, a system-wide chief medical officer council, a system-wide infection control and antibiotic stewardship program, and a central PI and project management office.

"David brings to UC Davis broad experience and proven results in a major healthcare market," May said. "He has an impressive record of sound financial management and innovative practices for a high functioning health care system that has gained national attention. His success in raising funds to meet pressing needs, including for enhanced access to Medicaid and indigent patients, aligns well with our values at UC Davis Health."

Lubarsky has been recognized for his success in helping establish a centralized scheduling system, improving infrastructure, and improving performance across many areas of the University of Miami health system. He raised more than $100 million annually for the University of Miami from state and federal funding sources to aid enhanced access for Medicaid and indigent patients. Previously, as CEO of the 1,100-physician practice, he turned a $100 million loss into a $32 million surplus in one year by growing patient volumes and optimizing the revenue cycle while making sure already high patient experience scores were maintained. Of note, every one of his major initiatives has explicitly prioritized quality and empathetic patient care.

In his efforts to meet community needs, Lubarsky has worked with the state of Florida and Centers for Medicare & Medicaid Services to expand access to Medicaid, forging a close partnership with the other major academic centers in Florida in pursuit of this goal. He has also been working with Florida’s state and congressional representatives to expand existing graduate medical education programs that would best meet the state’s needs and to secure the necessary federal funding which has been frozen for more than 20 years.

For the last 16 years, Lubarsky has been chief of service of anesthesia and pain management for the largest safety net hospital in the U.S., Jackson Memorial Hospital. He served on their board overseeing safety and quality, and throughout his tenure has been a forceful advocate for a uniform high quality of care.

"It is a privilege to join this highly regarded, progressive and nationally recognized health system," Lubarsky said. "I look forward to working closely with the accomplished faculty and staff, and routinely interacting with Davis’ talented students and trainees. I have already heard many great ideas about how to catapult Davis to greater heights, and I hope to harness those ideas to catalyze innovation so that we better serve our patients, our local community and our academic mission."

UC Davis School of Medicine is one of the nation's leading medical schools, recognized for its research and primary-care programs. Ranked 34th in National Institutes of Health funding in 2013, it is designated as one of the nation’s inaugural Clinical Translational Science Centers.

A few highlights include:

  • A national reputation for life-changing biomedical discoveries
  • A passion for clinical care and a commitment to engaging people from underserved communities and advancing rural health
  • Fully accredited master’s degree programs in public health and in informatics
  • A combined M.D.-Ph.D. program that is training the next generation of physician-scientists to conduct high-impact research and translate discoveries into better clinical care

The Dean’s Departments and Offices include:

Additional departments:

To learn more, visit the medical school site.

UC Davis Medical Center, based in Sacramento, Calif., is a nationally renowned academic medical center where clinical practice, teaching and research converge to advance human health.

A few highlights:

  • A 627-bed multispecialty academic medical center
  • Serves 33 counties covering a 65,000-square-mile area north to the Oregon border and east to Nevada
  • Recognized as one of the “Most Wired” hospitals in the U.S.
  • Recognized by The Leapfrog Group as a “Top Hospital” for delivery of high-quality care
  • Ranked Sacramento's top hospital by U.S. News & World Report

Centers of excellence include:

  • UC Davis Comprehensive Cancer Center, one of only 41 National Cancer Institute-designated comprehensive centers nationwide
  • State-of-the-art emergency departments that include the region's only Level I adult and pediatric trauma centers
  • The internationally recognized UC Davis MIND Institute, devoted to finding treatments and cures for neurodevelopmental disorders
  • UC Davis Children's Hospital, a nationally ranked pediatric hospital with more than 120 physicians in 33 pediatric subspecialties
  • A pioneering telehealth program, which gives remote, underserved communities access to academic specialty and subspecialty care

To learn more, visit the medical center site.

The Betty Irene Moore School of Nursing at UC Davis cultivates academic excellence and addresses urgent, societal needs through leadership development, interprofessional education, transformative research, cultural inclusiveness and innovative technology. The school plays a critical role in preparing nurse leaders who will shape the future of health care and inform health policy.

The School of Nursing has five research focus areas: chronic disease management, health technology, pain management, Healthy People and Healthy Systems. Faculty come from a wide range of backgrounds including nursing, business administration, sociology, gerontology, medicine, information technology and psychology. School of Nursing students engage in classroom and clinical environments with students in the School of Medicine, health informatics and other health-related programs.

A few highlights include:

To learn more, visit the School of Nursing’s website.

The Practice Management Group (TPMG) represents all organized medical group practices of UC Davis Health System’s primary and specialty care faculty physicians. The group's purpose is to serve the health system’s missions through high-quality, cost-effective care delivery. By delegation from the Office of the Vice Chancellor and Dean, TPMG has shared responsibility for the clinical operations of the health system's professional practice activities.

The formation of TPMG is an important step in formalizing the leadership of the health system's medical group practices and in refining the role of its group practice in achieving the health system's research, teaching, patient care and community engagement goals. Its primary goal is to maintain a clinical practice that distinguishes UC Davis Health System as a leading faculty and academic health center.

Specific goals of TPMG include:

  • Increasing efficiency of practice and revenue
  • Decreasing practice expenses
  • Reducing silos and improving integration
  • Identifying areas to increase quality
  • Aligning incentives

David H. Wisner is the executive director of the Practice Management Group, overseeing faculty practice operations as well as the overall vision and strategic direction of TPMG and its day-to-day activities. Wisner collaborates with the leadership of the School of Medicine and medical center to set and achieve joint strategic goals across the health system.

More information