Ishwarlal Jialal, professor of pathology and laboratory medicine, was selected to receive the 2012 Garry Labbe Award from the American Association of Clinical Chemistry for his outstanding work in the field of nutrition. He will receive a commemorative plaque and present on the "Nutritional modulation of the metabolic syndrome" at the annual association meeting in Los Angeles on July 17.
Jialal holds the Robert E. Stowell Endowed Chair in Experimental Pathology and is director of the Laboratory for Atherosclerosis and Metabolic Research at UC Davis Health System. He is a specialist in cardiovascular pathology, diabetes and clinical chemistry who conducts leading-edge research on oxidative stress and inflammation in atherosclerosis, cellular dysfunction and the role of inflammation in metabolic syndrome, and the pathobiology of diabetic vasculopathies.
His recent research demonstrates that not all obesity is the same and that some body fat may actually be toxic, releasing biomarkers associated with insulin resistance and chronic inflammation -- conditions often leading to diabetes and cardiovascular disease. By addressing this dysfunction of fat cells with existing or novel drug therapies, he believes it may be possible to block the production of damaging biomarkers. Through his studies on diabetes and heart disease, he has identified a leukocyte receptor as a key suspect in the destructive inflammation that underlies these chronic diseases.
"Dr. Jialal is advancing knowledge of the underlying pathobiology for the nation's leading causes of death and disability," said Lydia Howell, professor and chair of pathology and laboratory medicine at UC Davis Health System. "His work is a key step in identifying interventions that will improve health."
Jialal has published more than 420 original papers and invited reviews, and his research has been funded by the National Institutes of Health, American Diabetes Association, Juvenile Diabetes Research Foundation and American Heart Association.
"It is a great honor to receive this award, which is named after two outstanding clinical scientists who made seminal observations in nutrition research," Jialal said.
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