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February 2018arrow

UC Davis School of Medicine research funding ranks among the top 26 institutions in the U.S.

February 16, 2018

For the first time, UC Davis School of Medicine has ranked in the top 20 percent of institutions in the country for research funding from the National Institutes of Health (NIH).  

New study to evaluate the potential links between ozone and COPD

February 14, 2018

Angela Haczku, a leading researcher on environmental causes for airway inflammation, will receive more than $900,000 from the Tobacco Related-Disease Research Program to study chronic obstructive pulmonary disease (COPD) and ozone, a toxic component of urban smog.

A small pay increase can have big health benefits for lower-wage workers

February 9, 2018

Lower-wage workers who receive a $1 raise call in sick less and consider themselves healthier than those who do not, new UC Davis research on minimum-wage policies shows.

Young cancer survivors' risk of heart disease related to race and socioeconomic factors

February 9, 2018

Adolescent and young adult cancer survivors who are African American, poor or have public or no health insurance are far more likely to suffer from coronary artery disease, heart failure or stroke later in life than non-Hispanic white cancer survivors.

Traveling hands-on exhibit visits UC Davis Medical Center, Feb. 6 and 9

February 6, 2018

UC Davis Health is hosting the National Institutes of Health’s All of Us Journey, a traveling, hands-on exhibit to raise awareness about precision medicine and the All of Us research program.

Northern Californians asked to complete fire impacts survey

February 5, 2018

UC Davis public health researchers are conducting a comprehensive assessment of the health effects of the Northern California fires in October. They are asking one person per household in Napa, Sonoma and other counties affected by the fires to answer an online questionnaire — called the UC Davis Northern California Fire and Health Impacts Survey — about their daily lives, property and health before the fires occurred and immediately afterward, along with their current situations.

New research suggests your own immune system can protect against MRSA infections

February 5, 2018

After years of investigation, researchers at UC Davis, Johns Hopkins, and the National Institute of Allergy and Infectious Diseases have discovered how the immune system might protect a person from recurrent bacterial skin infections caused by Staphylococcus aureus (staph). The findings, publishing online this week in The Journal of Clinical Investigation, open new doors to someday developing vaccines to prevent staph skin infections, which account for 14 million outpatient visits, nearly 500,000 hospital admissions and $3 billion to $4 billion in inpatient health care costs in the U.S. per year.

January 2018arrow

National study finds substantial unmet needs for mental health care among veterans of recent wars

January 31, 2018

A new congressionally mandated report from the National Academies of Sciences, Engineering, and Medicine released today has concluded that there is a substantial unmet need for mental health services among veterans of the recent wars in Afghanistan and Iraq. 

Talamantes honored as an Emerging Scholar

January 25, 2018

Efrain Talamantes, an assistant professor of internal medicine and an expert in advancing equity and diversity in the field of medicine, has been named an Emerging Scholar for 2018 by the publication Diverse: Issues in Higher Education.

Researchers say medical licensing test should include more prescription drug safety, misuse questions

January 24, 2018

Research led by experts from the UC Davis schools of medicine and nursing has identified gaps in pain-related education for health care providers that leave out important aspects of safe and effective pain management competencies, including those specific to opioid safety. These findings, said the researchers, may help explain one reason for the current public health crisis of inappropriate pain management and prescription drug abuse.

Testing Sonoma ash and air for fire-formed pollutants

January 23, 2018

When fires ripped through suburban subdivisions in Santa Rosa last October, they may have done more than reduce homes to ashes. By incinerating all kinds of materials — insulation, electronics, furniture, cleaning products, pesticides — at very high temperatures, they could have created unknown or previously unrecognized health hazards in the smoke and ash. Researchers from the University of California, Davis, are trying to figure out just what is in that ash and air.

UC Davis researcher urges caution on engineered stem cells

January 3, 2018

In a commentary published today in the New England Journal of Medicine, UC Davis researcher William Murphy expressed cautious optimism about efforts to genetically engineer hematopoietic stem cells (HSCs) to temporarily resist cell death during transplantation. While these gene therapy approaches could dramatically improve patient outcomes, Murphy argues that their risks must be carefully studied in diverse animal models.

December 2017arrow

Ophthalmologists increasingly dissatisfied with electronic health records

December 28, 2017

Ophthalmologists’ use of electronic health records (EHR) systems for storing and accessing patients’ medical histories more than doubled between 2006 and 2016, while their perceptions of financial and clinical productivity following EHR implementation declined, a study published today in JAMA Ophthalmology shows.

New grant funds study of immune cell activity in stem cell transplantation

December 21, 2017

A team of UC Davis investigators has been awarded a $1.2 million grant to examine a common virus and its effects on immune system function after stem cell transplantation.

Enhanced natural killer cells attack solid tumors

December 19, 2017

Human and veterinary researchers at UC Davis and other institutions have shown that enhanced natural killer (NK) immune cells, combined with radiation therapy, can be effective against spontaneous osteosarcoma (bone cancer) in dogs. The research showed these NK cells homed in on cancer and reduced metastasis in the treated dogs, offering a potential immunotherapy against solid tumors. The study was published today in the Journal for Immunotherapy of Cancer

Impact of medical marijuana laws on teen substance use differs by grade

December 14, 2017

A study assessing the impact of medical marijuana laws (MML) on adolescent substance use  has found decreased use of all substances among 8th graders, no change among 10th graders and increased non-medical use of prescription opioids and cigarette use among 12th graders, following MML enactment.

More new moms need recommended postpartum care

December 14, 2017

About half of new moms in California, including those with diabetes, do not receive critical follow-up care within three months after giving birth, a new study published in the December issue of the journal Contraception shows.

Microscope that uses ultraviolet instead of visible light emerging as powerful diagnostic tool

December 4, 2017

A microscope using ultraviolet light to illuminate samples enables pathologists to assess high-resolution images of biopsies and other fresh tissue samples for disease within minutes, without requiring the time-consuming preparation of conventional slides or destroying the tissue.

November 2017arrow

Statewide survey finds physicians, pharmacists comply with prescription drug monitoring registration. Next step: increase use

November 29, 2017

A state law that funded upgrades to California’s prescription drug monitoring program and mandated physicians, pharmacists and controlled substance prescribers to register by July 2016 significantly increased registration rates, a new survey of 1,904 California physicians and pharmacists conducted by the UC Davis Violence Prevention Program has found.

Denying patient requests lowers physician ratings

November 27, 2017

Patients who ask for specialist referrals, laboratory tests or certain medications and don’t get them tend to be less satisfied with their doctors than those whose requests are fulfilled, new research from UC Davis Health shows. Based on the results, the study authors recommend communications training for physicians that fosters positive experiences for patients without agreeing to all requests for particular diagnostics or treatments.

Study shows long-term benefits of steroid hormone medications in Duchenne muscular dystrophy

November 27, 2017

A large, multi-center, international study to assess the long-term benefits of glucocorticoid treatment for Duchenne muscular dystrophy (DMD) concludes that it does preserve muscle strength and function as well as reduce the risk of death for patients.

UC study finds performance on med school interviews linked to demographics

November 21, 2017

The medical school interview – a key determinant in the admissions process and, ultimately, in the physician workforce – appears to skew for or against applicants depending on their age, gender and self-identified disadvantaged socioeconomic status.

Maternal immune response affects genes in microglia, neural development

November 20, 2017

UC Davis MIND Institute esearchers have shown in a mouse model that an elevated maternal immune response changes the epigenetic landscape in offspring’s microglia, immune cells found in the brain and spinal cord. These changes affect genes associated with immune signaling and neural development, some of which have been implicated in autism spectrum disorder (ASD). The study was published online in the journal Glia.

In cancer, talking about bad news can be good

November 17, 2017

Giving bad news is never easy, especially when it’s life or death. But when an oncologist delivers a poor prognosis to a cancer patient, does it harm their relationship?  Some research studies have suggested it can.

Unlocking the genetics of cancer

November 7, 2017

For many, breast cancer is more than just a disease – it’s personal. One in eight women will be diagnosed with breast cancer at some point in their lives. But through new discoveries at the genetic level, the personal nature of cancer will eventually be what helps to beat it.

October 2017arrow

Peers can reduce tobacco use among younger smokers

October 25, 2017

Participating in a brief intervention delivered by their peers in community settings can help reduce smoking among youth and young adults, a new study from a team of tobacco-cessation researchers shows.

MIND Institute researchers detect reversal of behavioral deficits in a rare genetic disorder

October 23, 2017

Research conducted in mice at the UC Davis MIND Institute suggests that a drug treatment can reverse cognitive deficits and social abnormalities in a rare genetic disorder, 16p11.2 deletion syndrome, which includes symptoms of intellectual disability and autism spectrum disorder, among others. Results of parallel studies conducted at the MIND and at the Massachusetts Institute of Technology Picower Institute for Learning and Memory appear in the latest issue of the journal Neuropsychopharmacology.

Moonshot grant advances immune therapy for dogs - and one day people - with cancer

October 20, 2017

UC Davis has received its first National Cancer Institute (NCI) Moonshot grant  ̶  $2.5 million over five years  ̶  to explore immunotherapy treatments for dogs who develop melanoma and osteosarcoma and that may one day benefit humans, as well.

Cancer Center hosts lung cancer research conference

October 19, 2017

Members of the UC Davis Comprehensive Cancer Center lung cancer treatment team will present at WCLC 2017, a one-day conference on Saturday, Nov. 11, from 7 a.m. to 4 p.m. in San Francisco. Presenters will share the latest lung cancer and other thoracic malignancy advances highlighted at the recent 18th Annual World Conference on Lung Cancer in Japan.

Noncompliance thwarts comprehensive background check policy for private-party sales, study finds

October 9, 2017

Of the three states that recently expanded comprehensive background check (CBC) policies to include all gun transfers, including those among private parties, only Delaware showed an overall increase in firearm background checks. Washington and Colorado had no changes, which the study authors say suggests that compliance and enforcement were incomplete.

"Smart" immune cells: Emerging cancer therapy research at UC Davis receives a boost with NIH award

October 6, 2017

Assistant Professor Sean Collins, Department of Microbiology and Molecular Genetics, has received a $1.5 million award from the National Institutes of Health to advance the development of “smart” immune cells for therapies to treat cancer and other diseases. The five-year NIH Director’s New Innovator Award aims to provide new insight into how to engineer immune cells to control their recruitment and response to tumors.

September 2017arrow

UC Davis receives $8 million to expand access to stem cell clinical trials

September 28, 2017

The California Institute for Regenerative Medicine today awarded a nearly $8 million grant to University of California, Davis, stem cell researchers to launch a special clinical trials program in Sacramento to accelerate the therapeutic development and delivery of stem cell therapies in human patients.

$3.3 million grant funds early detection of pancreatic cancer

September 27, 2017

UC Davis researchers, led by Julie Sutcliffe, have received a $3.3 million grant from the National Institutes of Health to advance efforts to diagnose pancreatic cancer before it spreads.

Too little is known about the compounds in wildfire smoke

September 25, 2017

How do fire-suppression chemicals and pesticides affect wildfire smoke and the health of those who breathe it? UC Davis graduate students discovered that this question cannot be answered based on current scientific evidence and, in a review published in Current Topics in Toxicology, they recommend more studies on the compounds in wildfire smoke.

UC Davis MIND Institute wins coveted ACE grant

September 7, 2017

The UC Davis MIND Institute has been awarded a 5-year, $12 million Autism Centers of Excellence (ACE) grant, one of five in the nation, to create a “Center for the Development of Phenotype-based Treatments of Autism Spectrum Disorder.”

August 2017arrow

Knoepfler awarded second Alex's Lemonade Stand research grant

August 30, 2017

UC Davis stem cell scientist Paul Knoepfler has been awarded a second $250,000 grant for glioma research from an organization begun 15 years ago by a 5-year-old girl with a deadly form of childhood cancer.

Stem cell treatment for children with spina bifida helps dogs first

August 24, 2017

A pair of English bulldog puppies are the first patients to be successfully treated with a unique therapy — a combination of surgery and stem cells — developed at the University of California, Davis, to help preserve lower-limb function in children with spina bifida.

Before sarcoma surgery - radiation

August 18, 2017

UC Davis researchers have shown that radiation therapy before surgery improves overall survival for patients with soft tissue sarcomas. This pre-surgical, or neoadjuvant, radiotherapy allows surgeons to get better margins around tumors and remove even microscopic cancer tissue more often. The study was published recently  in the Annals of Surgical Oncology.

Study of California kidney cancer shows declining incidence, end of a trend

August 18, 2017

A review of kidney cancer in California from 1988 through 2013 by the UC Davis Institute for Population Health Improvement (IPHI) has concluded that the high incidence of small tumors and early-stage disease observed in California from 1988 until about 2009 has declined and stabilized in recent years, signaling the end of a trend.

Impulsivity in teens, young adults subject of $3.7 million UC Davis grant

August 11, 2017

Julie Schweitzer, a professor in the Department of Psychiatry and Behavioral Sciences and UC Davis MIND Institute researcher, has received a $3.7 million grant from the National Institute of Mental Health (NIMH) to track impulsivity and self-control in teens and young adults over time.

July 2017arrow

Health plans that shared best practices improved hypertension control for low-income Californians

July 31, 2017

Health plans that collaborated to share best practices and successful strategies for treating patients diagnosed with hypertension saw significant improvement in controlling high blood pressure, a study by the California Department of Health Care Services (DHCS) and UC Davis Institute of Population Health Improvement (IPHI) has found.

Med student focusing on brain research awarded 2017 O'Connor research grant

July 28, 2017

John Paul Aboubechara, a fifth-year student in the combined M.D./Ph.D. program at UC Davis School of Medicine, has been honored with this year’s Daniel T. O’Connor, M.D., Memorial Research Grant.

Massive study launched to test personalized approach to breast cancer screening

July 26, 2017

Sorting out when or whether to get mammograms can be perplexing for any woman, and a health provider’s advice may not settle the matter. That’s because even experts disagree about when screening mammography is appropriate and for whom.

UC Davis to lead $14 million Alzheimer's disease study in Latinos

July 25, 2017

The University of California has been awarded a nearly $14.7 million multi-year grant from the National Institutes of Health to study contributors to dementia in the Latino population in the United States. The multicenter study will examine the biological underpinnings of stroke, mild cognitive impairment and Alzheimer’s disease among Hispanics, and pursue new therapeutic directions to reduce brain health disparities.  

UC Firearm Violence Prevention Research Center launched at UC Davis

July 24, 2017

The University of California Firearm Violence Research Center at UC Davis’ Sacramento campus officially launched July 4 under the direction of Garen Wintemute, a professor of emergency medicine and recognized authority on the epidemiology of firearm violence. 

Clinical trial shows some promise for Duchenne muscular dystrophy drug

July 18, 2017

The results of an international clinical trial, led in part by a UC Davis School of Medicine expert, have shown that a drug therapy for a severe type of muscular dystrophy holds promise for a subgroup of patients.

Kuppermann gets award of a lifetime

July 14, 2017

The Society for Academic Emergency Medicine (SAEM) recently honored Nate Kuppermann with more than just a lifetime award for meritorious accomplishments in research and mentorship.

Chronic liver inflammation linked to Western diet, mouse study finds

July 12, 2017

A new study published today in The American Journal of Pathologyfound  that mice fed a high-fat, high-sugar Western diet developed hepatic inflammation, which was more common in males than females and most pronounced in mice that also lacked a bile acid receptor known as farnesoid x receptor, or FXR.

Life-saving Umbilical Cord Blood Collection Program extended 5 years

July 11, 2017

In a decisive move by the Governor and Legislature, the University of California Umbilical Cord Blood Collection Program (UCBCP) has been extended through 2022. The program enables mothers of newborns to donate their babies’ umbilical cord blood and have it publicly banked so it is available to anyone for lifesaving transplantations.

UC Davis physician honored for Huntington's disease work

July 10, 2017

The Northern California chapter of Huntington’s Disease Society of American (HDSA) has honored UC Davis Health’s Lorin Scher for his outstanding service to the Huntington’s disease community in the Sacramento region.

June 2017arrow

UC Davis Health, Sacramento Fire partnering to improve emergency care for children

June 28, 2017

UC Davis Health and the Sacramento City Fire Department have established a research partnership that aims to improve care for sick and injured children during and after an emergency transport.

Researchers validate mouse model for autism

June 22, 2017

Researchers at the UC Davis MIND Institute and Boston Children’s Hospital have confirmed that mice without the Shank3B protein model aspects of brain physiology and behavioral symptoms observed in people with autism. The findings confirm that Shank3B knockout mice provide a valuable research tool for future efforts to develop new therapies. The study, supported by Autism Speaks, was published in the journal Molecular Autism.

Study debunks claim of greatly improved survival rate for gunshot victims

June 22, 2017

The survival rate of U.S. gunshot victims has not shown a marked improvement, as other recent studies have suggested, according to new research from Duke University and the University of California, Davis.

Ultrasound for children with abdominal trauma

June 13, 2017

Despite evidence showing that the routine use of sonography in hospital emergency departments can safely improve care for adults when evaluating for possible abdominal trauma injuries, researchers at UC Davis Medical Center could not identify any significant improvements in care for pediatric trauma patients.

How treating a dog's tumors may help in the fight against human cancer

June 6, 2017

With its internationally renowned school of veterinary medicine and its NCI-designated comprehensive cancer center, UC Davis is uniquely positioned to harness the power of each to tackle one of life’s greatest challenges: cancer.

How gender, diet, microbiota and molecules contribute to metabolic disease and liver cancer

June 6, 2017

Researchers at UC Davis Health and other institutions have shown that gender differences in mice microbiota can modulate the risk of developing metabolic disease and liver cancer. In addition, the team found that a bile acid receptor protein, called FXR, has a profound impact on mouse microbiota and bile acid profiles and is differentially expressed based on gender. The study was published in the journal Scientific Reports.

May 2017arrow

UC Davis signs agreement to license novel CT scanning technology

May 24, 2017

UC Davis has signed a licensing agreement providing Isotropic Imaging Corporation the rights to commercialize a novel computed tomography (CT) scanner that has the potential to improve breast cancer detection and positively impact women’s health.

UC Davis Duchenne team honored by national parent organization

May 5, 2017

The UC Davis Neuromuscular Research Center has been recognized as a Certified Duchenne Care Center by Parent Project Muscular Dystrophy for national leadership in treating Duchenne muscular dystrophy.

April 2017arrow

Less is best when treating burn patients with blood transfusions

April 26, 2017

Reducing by half the typical amount of blood provided through transfusions to burn patients makes no difference in terms of patient outcomes, a new multi-center study led by UC Davis researchers shows.

Early cancer deaths linked to being single, living in a poor neighborhood

April 25, 2017

Patients in California hospitals were more likely to die within 60 days of being diagnosed with acute myeloid leukemia – a cancer of the blood and bone marrow – if they were unmarried, lived in a less-affluent neighborhood or lacked health insurance. The UC Davis study also found that patients treated at a National Cancer Institute (NCI)-designated cancer center were more likely to survive.

Second cancers deadlier in young patients

April 20, 2017

Second cancers in children and adolescents and young adults (AYA) are far deadlier than they are in older adults and may partially account for the relatively poor outcomes of cancer patients ages 15-39 overall, a new study by UC Davis researchers has found.

Improving outcomes for adults with autism spectrum disorder

April 7, 2017

Adults with autism spectrum disorder (ASD) will be the topic of the next Minds behind the MIND lecture on April 19 at 5:30 p.m. at the UC Davis MIND Institute, 2825 50th St. in Sacramento. The lecture is free and open to the public.

March 2017arrow

Hitting cancer with high-intensity ultrasound and immunotherapy

March 23, 2017

In a new study published today in JCI Insight, UC Davis researchers have shown that combining high-intensity focused ultrasound with two immunotherapies (a PD-1 checkpoint inhibitor and TLR9 agonist) can produce excellent response rates in mouse models of epithelial cancer. They also found that, for the combination to be effective, immunotherapies must come first.

UC Davis researchers investigate adult blood-clotting drug for use in severely injured children

March 14, 2017

UC Davis emergency medicine researchers have been awarded a grant from the National Institutes of Health (National Heart, Lung, and Blood Institute) to investigate the safety and efficacy of a drug known to stop bleeding in injured adults for use in cases of pediatric trauma.

How H. pylori thrives in the highly acidic stomach

March 9, 2017

An international team of reseachers led by Thomas Borén at Umeå University and including Jay Solnick, professor internal medicine at UC Davis, has discovered the tmechanism that gives the bacteria such staying-power and ability to cause chronic infection.

Developing new collaborations and technologies

March 7, 2017

With a $1 million grant from the National Science Foundation (NSF), UC Davis and Boston University will focus on establishing partnerships with industry, academe and government that lead to the development of innovative biophotonic technologies for use in medicine and other scientific disciplines.

University of California, Stanford partner on research to improve health in California and nationwide

March 7, 2017

The University of California Biomedical Research Acceleration, Integration, and Development program (UC BRAID) and Stanford University have formed an alliance to combine resources and develop a coordinated approach to research targeting the health of Californians – a partnership that can serve as a model for collaborations throughout the country.

UC Davis joins national consortium to find regenerative treatments for dental and craniofacial tissues

March 7, 2017

UC Davis will join other California research institutions in a three-year, $12 million effort to find regenerative treatments for dental, oral and craniofacial deformities and injuries.

Doctors and patients often disagree on pain treatment goals

March 6, 2017

Disagreements between doctors and patients over the priorities of pain treatment are common during primary care office visits, new research from UC Davis Health shows. Patients hope to reduce pain intensity and identify the cause, while physicians aim to improve physical function and reduce medication side effects, including dependency.

Cerebrospinal fluid shows promise as autism biomarker

March 6, 2017

Researchers from the UC Davis MIND Institute, University of North Carolina (UNC) and other institutions have found that altered distribution of cerebrospinal fluid (CSF) in high-risk infants can predict whether they will develop autism spectrum disorder (ASD). The study appears today in the journal Biological Psychiatry.