UC Davis research news releases
June 22, 2017
The survival rate of U.S. gunshot victims has not shown a marked improvement, as other recent studies have suggested, according to new research from Duke University and the University of California, Davis.
June 22, 2017
Researchers at the UC Davis MIND Institute and Boston Children’s Hospital have confirmed that mice without the Shank3B protein model aspects of brain physiology and behavioral symptoms observed in people with autism. The findings confirm that Shank3B knockout mice provide a valuable research tool for future efforts to develop new therapies. The study, supported by Autism Speaks, was published in the journal Molecular Autism.
June 13, 2017
Despite evidence showing that the routine use of sonography in hospital emergency departments can safely improve care for adults when evaluating for possible abdominal trauma injuries, researchers at UC Davis Medical Center could not identify any significant improvements in care for pediatric trauma patients.
June 6, 2017
With its internationally renowned school of veterinary medicine and its NCI-designated comprehensive cancer center, UC Davis is uniquely positioned to harness the power of each to tackle one of life’s greatest challenges: cancer.
June 6, 2017
Researchers at UC Davis Health and other institutions have shown that gender differences in mice microbiota can modulate the risk of developing metabolic disease and liver cancer. In addition, the team found that a bile acid receptor protein, called FXR, has a profound impact on mouse microbiota and bile acid profiles and is differentially expressed based on gender. The study was published in the journal Scientific Reports.
May 24, 2017
UC Davis has signed a licensing agreement providing Isotropic Imaging Corporation the rights to commercialize a novel computed tomography (CT) scanner that has the potential to improve breast cancer detection and positively impact women’s health.
May 5, 2017
The UC Davis Neuromuscular Research Center has been recognized as a Certified Duchenne Care Center by Parent Project Muscular Dystrophy for national leadership in treating Duchenne muscular dystrophy.
April 26, 2017
Reducing by half the typical amount of blood provided through transfusions to burn patients makes no difference in terms of patient outcomes, a new multi-center study led by UC Davis researchers shows.
April 25, 2017
Patients in California hospitals were more likely to die within 60 days of being diagnosed with acute myeloid leukemia – a cancer of the blood and bone marrow – if they were unmarried, lived in a less-affluent neighborhood or lacked health insurance. The UC Davis study also found that patients treated at a National Cancer Institute (NCI)-designated cancer center were more likely to survive.
April 20, 2017
Second cancers in children and adolescents and young adults (AYA) are far deadlier than they are in older adults and may partially account for the relatively poor outcomes of cancer patients ages 15-39 overall, a new study by UC Davis researchers has found.
April 7, 2017
Adults with autism spectrum disorder (ASD) will be the topic of the next Minds behind the MIND lecture on April 19 at 5:30 p.m. at the UC Davis MIND Institute, 2825 50th St. in Sacramento. The lecture is free and open to the public.
March 23, 2017
In a new study published today in JCI Insight, UC Davis researchers have shown that combining high-intensity focused ultrasound with two immunotherapies (a PD-1 checkpoint inhibitor and TLR9 agonist) can produce excellent response rates in mouse models of epithelial cancer. They also found that, for the combination to be effective, immunotherapies must come first.
March 14, 2017
UC Davis emergency medicine researchers have been awarded a grant from the National Institutes of Health (National Heart, Lung, and Blood Institute) to investigate the safety and efficacy of a drug known to stop bleeding in injured adults for use in cases of pediatric trauma.
March 9, 2017
An international team of reseachers led by Thomas Borén at Umeå University and including Jay Solnick, professor internal medicine at UC Davis, has discovered the tmechanism that gives the bacteria such staying-power and ability to cause chronic infection.
March 7, 2017
With a $1 million grant from the National Science Foundation (NSF), UC Davis and Boston University will focus on establishing partnerships with industry, academe and government that lead to the development of innovative biophotonic technologies for use in medicine and other scientific disciplines.
University of California, Stanford partner on research to improve health in California and nationwide
March 7, 2017
The University of California Biomedical Research Acceleration, Integration, and Development program (UC BRAID) and Stanford University have formed an alliance to combine resources and develop a coordinated approach to research targeting the health of Californians – a partnership that can serve as a model for collaborations throughout the country.
UC Davis joins national consortium to find regenerative treatments for dental and craniofacial tissues
March 7, 2017
UC Davis will join other California research institutions in a three-year, $12 million effort to find regenerative treatments for dental, oral and craniofacial deformities and injuries.
March 6, 2017
Disagreements between doctors and patients over the priorities of pain treatment are common during primary care office visits, new research from UC Davis Health shows. Patients hope to reduce pain intensity and identify the cause, while physicians aim to improve physical function and reduce medication side effects, including dependency.
March 6, 2017
Researchers from the UC Davis MIND Institute, University of North Carolina (UNC) and other institutions have found that altered distribution of cerebrospinal fluid (CSF) in high-risk infants can predict whether they will develop autism spectrum disorder (ASD). The study appears today in the journal Biological Psychiatry.
UC Davis computational molecular biologist named Sloan fellow to study genetic causes of complex disorders
February 27, 2017
Fereydoun Hormozdiari, an early-career UC Davis scientist, has been named a 2017 Alfred P. Sloan Research Fellow in Computational & Evolutionary Molecular Biology. He is one of 126 scholars to receive the prestigious award, which comes with $60,000 over two years to conduct leading-edge research.
February 23, 2017
Researchers at UC Davis have received $3.2 million in federal funds to further investigate how obesity and inflammation affect the body’s immune system in fighting cancer.
February 21, 2017
In two recent studies, researchers at UC Davis have shown that the placenta can provide critical information about early changes to the intra-uterine environment that may influence fetal development and ultimately, children’s brains.
February 10, 2017
Language barriers may hinder U.S. kidney transplant candidates’ access to kidney transplantation, according to a new study in the Clinical Journal of the American Society of Nephrology. Led by a team from Cedars-Sinai, UCLA Health and UC Davis Health, the research suggests that patients who primarily speak a language other than English may face disparities that keep them from completing their kidney transplant evaluations and, ultimately, from receiving a transplant.
February 9, 2017
Older adults who live in poor and violent urban neighborhoods are at greater risk for depression, a study by researchers from UC Davis, the University of Minnesota and other institutions published Jan. 23 in the journal Health & Place has found.
February 7, 2017
UC Davis physician researchers have found that medical marijuana contains multiple bacterial and fungal pathogens that may cause serious and even fatal infections. They warn that smoking, vaping or inhaling aerosolized marijuana could pose a grave risk to patients, especially those with leukemia, lymphoma, AIDS or conditions requiring immune-suppressing therapies.
January 31, 2017
Researchers at UC Davis have published a study that illustrates how maternal immune activation could affect neurodevelopment in offspring.
January 30, 2017
Among individuals who legally purchased handguns in California, prior convictions for driving under the influence (DUI) and other alcohol-related crimes were associated with a substantial increase in risk for subsequent violent or firearm-related crime, according to a study published Jan. 30 in Injury Prevention by the UC Davis Violence Prevention Research Program.
January 19, 2017
A large team of researchers from UC Davis and several European and Latin American institutions have identified genetic variations that contribute to familial gastric cancer. These inherited mutations, which affect the PALB2, BRCA1 and RAD51C genes and have been implicated in other cancer types, impair a critical DNA repair mechanism called homologous recombination. These findings could improve preventive care, as well as provide targets for new therapies. The study was published last month in the journal Gastroenterology.
January 18, 2017
A national study by researchers at UC Davis Comprehensive Cancer Center has found that a significant number of lung cancer patients are not receiving treatment. Based on data between 1998 and 2012 from the National Cancer Database, 21 percent of patients (190,539) with non-small cell lung cancer (NSCLC) received no specific cancer treatment, such as chemotherapy, radiotherapy or surgery. Many of the untreated patients were women, elderly, minorities, low income and uninsured.
January 9, 2017
UC Davis Health has entered into an agreement with Top Grade Health Care to establish a translational research and development center to advance the treatment of patients with cancer.
December 28, 2016
The UC Davis MIND Institute is participating in a nationwide ADHD study using a scientifically designed video game-like technology.
December 27, 2016
Marijuana use significantly increased and its perceived harm decreased among eighth- and 10th-graders in Washington state following enactment of recreational marijuana laws, according to a UC Davis and Columbia University Mailman School of Public Health to be published online in JAMA Pediatrics. There was no change in use or perceived harm among 12th graders or among similar grades in Colorado.
December 22, 2016
In a study that could have significant impact on how disease outbreaks are managed, researchers at UC Davis and the California Department of Public Health (CDPH) have sequenced and analyzed genomes from Shigella sonnei (S. sonnei) bacteria associated with major shigellosis outbreaks in California in 2014 and 2015.
December 21, 2016
Factors such as advanced age and greater aerobic capacity increase the likelihood that exercise will work as a treatment for depression in elderly patients, a recent study published in the Journal of the American Geriatrics Society has shown.
December 15, 2016
Results of a UC-wide venous thromboembolism (VTE) prevention program, led by Gregory Maynard, chief quality officer for UC Davis Medical Center, have shown a significant reduction in hospital-associated VTEs at all five participating UC hospitals, according to a recently released study authored by Maynard and published in the December 2016 issue of the Journal of Hospital Medicine.
December 15, 2016
The UC Davis MIND Institute and Rush University Medical Center have been awarded $11.5 million from the National Institutes of Health to test a new therapy designed to improve language learning for children fragile X syndrome.
December 14, 2016
Strokes and heart attacks are rare for women with diabetes who use hormonal contraception, with the safest options being intrauterine devices (IUDs) and under-the-skin implants, new research published in Diabetes Care shows.
December 13, 2016
Researchers at UC Davis have shown that a well-known neurotoxin (PCB 95) and a chromosomal duplication (Dup15q) have a profound impact on DNA methylation, the epigenetic process that can influence gene activity. These cumulative genetic and environmental “hits” alter the epigenetic landscape during development, altering genes linked to autism spectrum disorder (ASD). The study was published in the journal Cell Reports.
December 12, 2016
A large trial by UC Davis professor David Gandara has found that the immunotherapy atezolizumab was superior to chemotherapy for patients with advanced non-small-cell lung cancer.
December 6, 2016
Greater weight increases the likelihood of hot flashes and night sweats during early stages of the menopause transition but reduces those symptoms throughout menopause and beyond, new UC Davis research published in the journal Menopause shows.
November 29, 2016
For the first time, researchers have found higher levels of Gram-negative bacteria antigens in brain samples from late-onset Alzheimer’s disease patients. Compared to controls, patients with Alzheimer's had much higher levels of lipopolysaccharide (LPS) and E coli K99 pili protein. In addition, The UC Davis team also found LPS molecules congregated with amyloid plaques, which have been linked to Alzheimer’s pathology and progression. The research was published today in the print edition of the journal Neurology.
November 23, 2016
Black infants had over twice the deaths of whites attributable to lack of optimal breastfeeding, a new study published in the Journal of Pediatrics shows. Black infants also had over three times the rate of necrotizing enterocolitis, a devastating disease of preterm infants, attributable to suboptimal rates of feeding with their mother’s own milk.
November 15, 2016
A UC Davis-led team has been awarded a $1.2 million grant from California Initiative to Advance Precision Medicine (CIAPM) to explore the use of personalized mobile health data to improve chronic disease management and care.
October 25, 2016
Patients with disseminated advanced cancer who undergo surgery are far more likely to endure long hospital stays and readmissions, referrals to extended care facilities and death, UC Davis researchers have found.
October 20, 2016
Two UC Davis researchers have received grants totaling $1.6 million to advance their work to find an effective treatment for Angelman syndrome, a rare genetic disorder that causes seizures and sleep disturbances and inhibits language development.
October 20, 2016
Painful sex in women after cancer treatment is relatively common, often treatable and needs to be addressed by medical providers, a UC Davis oncologist and researcher suggests.
October 19, 2016
Neu5Gc, a non-human sialic acid sugar molecule common in red meat that increases the risk of tumor formation in humans, is also prevalent in pig organs, with concentrations increasing as the organs are cooked, a study by researchers from the UC Davis School of Medicine and Xiamen University School of Medicine has found.
October 13, 2016
The National Institutes of Health (NIH) has named the California Precision Medicine Consortium as a regional medical center group in the national network of health care provider organizations that will implement the Precision Medicine Initiative (PMI) Cohort Program.
October 12, 2016
Researchers at UC Davis and the Xiamen University School of Medicine have found that a dangerous family of molecules called sialic acids (SIAs) are prevalent in piglet organs, with concentrations increasing as the organs are cooked. Of particular concern, a SIA called Neu5Gc was prevalent in piglet spleens and lungs. SIAs have been linked to cancer, cardiovascular disease and inflammation. The research was published in the Glycoconjugate Journal Sept. 9.
October 6, 2016
Of the 10 million prescriptions for antibiotics that emergency department physicians in the U.S. write each year, many are prescribed for known viral infections such as acute bronchitis and upper respiratory infections, which do not respond to antibiotics. A one-year study at UC Davis Medical Center funded with a grant from the U.S. Centers for Disease Control and Prevention is working to reduce inappropriate antibiotic prescribing and preserve the microbe-fighting power of antibiotics.
October 4, 2016
The 30-day window for hospital readmissions — used by the federal government to penalize hospitals believed to provide lower-quality care because patients return to the hospital following discharge — should be reduced to a week or less to more accurately measure factors within a hospital’s control, new research from UC Davis has found.
October 3, 2016
Neurosurgeons at UC Davis Health System have enrolled the first patient in a study that will determine if a new investigational treatment can safely and effectively improve motor function following acute traumatic cervical spinal cord injury.
September 30, 2016
Nancy Lane, endowed professor of medicine, rheumatology and aging, and director of the UC Davis Center for Musculoskeletal Health, has been honored by the American Society for Bone and Mineral Research (ASBMR) with its 2016 inaugural Steven M. Krane Award for her clinical research focused on osteoporosis and bone biology in patients with rheumatic diseases.
September 28, 2016
Breastfeeding as recommended — for a total of one year and exclusively for six months — could protect moms as well as their babies from premature death and serious diseases and save more than $4.3 billion in health care and related costs, according to a new study published online in Maternal & Child Nutrition.
September 27, 2016
Preventing skin scarring with red light-emitting diodes and using small molecules in the breath to detect infections are just two of several innovative projects developed at UC Davis Health System that are moving closer to becoming new treatments and tools for improving patient care, thanks to the mentored research programs of the UC Davis Clinical and Translational Science Center (CTSC) and the Emergency Medicine K12 program.
September 26, 2016
UC Davis will receive $3.9 million from the National Institutes of Health to join the first phase of a seven-year initiative called Environmental influences on Child Health Outcomes, or ECHO.
September 23, 2016
Kit Lam, professor and chair of the UC Davis Department of Biochemistry and Molecular Medicine, has received two major cancer research grants totaling more than $3 million.
September 16, 2016
Why do some foodborne bacteria make us sick? A paper published Sept. 16 in the journal Science has found that pathogens in the intestinal tract cause harm because they benefit from immune system responses designed to repair the very damage to the intestinal lining caused by the bacteria in the first place.
September 14, 2016
About one-third of 1,751 genes studied in the first comprehensive survey of the mouse genome are essential to life, according to research by an international collaboration including the University of California, Davis, Mouse Biology Program. Mutations of these genes cause death at the embryo stage. Many of them have counterparts in the human genome, so understanding why these genes are so vital could help prioritize human genes for study.
September 12, 2016
The University of California, Davis, has been awarded $29,290,259 from the National Institutes of Health under the next five-year phase of the Knockout Mouse Project. UC Davis is the lead organization in a consortium involving research partners at The Center for Phenogenomics in Toronto, Canada, the Childrens’ Hospital Oakland Research Institute and Charles River Laboratories in Wilmington, Mass.
September 9, 2016
Training oncologists and their patients to have high-quality discussions improves communication, but troubling gaps still exist between the two groups, according to a new study in JAMA Oncology.
Cognitive function tests reliable for people with intellectual disabilities, UC Davis research shows
September 6, 2016
Researchers at the UC Davis MIND Institute have found that a battery of tests appears to have strong potential for measuring cognitive changes over time for people with intellectual disabilities. The work could open new doors to research into whether drugs and specialized educational programs or treatments can improve function in people with Down syndrome, fragile X syndrome and other causes of intellectual disabilities.
September 6, 2016
The National Cancer Institute has again funded the K12 Paul Calabresi Clinical Oncology Training Grant to promote and sustain the development of young cancer scientists from diverse fields and from laboratories and clinics across both UC Davis campuses.
August 31, 2016
A new report from the UC Davis Institute for Population Health Improvement (IPHI) shows the impact of cancer screening over the past 15 years, identifying areas where increased screening and other cancer-control efforts would save lives and significantly benefit population health.
August 26, 2016
Treatment with sertraline may provide nominal but important improvements in cognition and social participation in very young children with fragile X syndrome, the most common genetic cause of intellectual disability and the leading single-gene cause of autism, a study by researchers with the UC Davis MIND Institute has found.
August 26, 2016
Hmong Americans are more likely to understand the importance of colorectal cancer screening and to get screened when they’re provided information by specially trained Hmong lay health educators, new research from UC Davis has found.
August 23, 2016
Physicians from Children’s Hospital of Michigan, UC Davis Medical Center and Nationwide Children's Hospital, in collaboration with 19 other pediatric emergency departments around the country, have established a “proof of principle” for measuring patterns of ribonucleic acid (RNA) expression in the bloodstream that can enable clinicians to distinguish bacterial infections from other causes of fever in infants up to two months old.
August 12, 2016
The U.S. Department of Defense has awarded $2 million to David Greenhalgh, a UC Davis surgeon and national leader in treating burn injuries, for a study of the outcomes of a fluid resuscitation treatment for burn patients.
August 11, 2016
Colorectal cancer incidence and mortality rates in California have decreased markedly for men and women in all major racial-ethnic groups since 1990, except for Hispanic men. Colorectal cancer rates for Hispanic men have remained relatively the same, a disparity that can be improved by greater screening, a study of colorectal cancer trends from the UC Davis Institute for Population Health Improvement (IPHI) finds.
August 10, 2016
Two physician scientists received seed funding from the UC Davis Office of Research’s Science Translation and Innovative Research (STAIR) program to help them demonstrate proof-of-concept and commercial feasibility of their innovative technologies, which aim to address unmet market needs.
August 5, 2016
The Prostate Cancer Foundation and Movember, the global charity that has raised hundreds of millions for men’s health research and programs, have delivered $1 million to UC Davis prostate cancer researchers.
August 2, 2016
Four cutting-edge studies, including one led by John Olichney, professor and neurologist at the UC Davis Alzheimer’s Disease Center, will each receive $1 million to advance current Alzheimer's research to the next stage of clinical trials. A unique, goal-driven competition offers an additional $3 million to the clinical trial that demonstrates the most promise for treating this devastating disease.
July 28, 2016
Researchers at UC Davis and Ionis Pharmaceuticals have developed a hybrid treatment that harnesses a monoclonal antibody to deliver antisense DNA to acute lymphoblastic leukemia (ALL) cells and that may lead to less toxic treatments for the disease.
July 27, 2016
The UC Davis MIND Institute kicks off its 2016-2017 Distinguished Lecturer Series in September with an address by Robert H. Ring, associate professor at Drexel University in the College of Medicine, Department of Pharmacology and Physiology.
July 26, 2016
Ralph de Vere White, who retired in June as director of the UC Davis Comprehensive Cancer Center, has been named to a key committee at the National Institute of Health (NIH).
July 21, 2016
The state stem cell agency, the California Institute for Regenerative Medicine (CIRM), today approved a $1.1 million grant to UC Davis for research aimed at developing a treatment for Angelman syndrome, a rare, neurogenetic autism-spectrum disorder that occurs in one in 15,000 live births.
July 20, 2016
Capitalizing on experimental genetic techniques, researchers at UC Davis’ California National Primate Research Center (CNPRC) have demonstrated that temporarily turning off an area of the brain changes patterns of activity across much of the remaining brain.
July 19, 2016
UC Davis researchers have found a way to get MRI images of children with autism spectrum disorder (ASD) and intellectual disability without sedating them first using the principles of applied behavior analysis.
July 14, 2016
Physical exams conducted from the 1960s through the 1980s will be revisited to evaluate risks and protective factors in early and midlife that could affect brain health and dementia diagnoses among a large, ethnically diverse group of seniors. The Kaiser Permanente Northern California Division of Research will partner with the UC Davis Alzheimer’s Disease Center for the study, which is funded with a five-year, $13 million grant from the National Institute on Aging.
July 14, 2016
Patients with stage III or IV cancer report far more optimistic expectations for survival than their oncologists thought they had communicated, according to new research published today in JAMA Oncology. Effective communication between doctors and their patients who could be nearing the end of their lives is crucial, according to the authors, since this is when quality-of-life decisions merge with discussions about treatment options.
July 12, 2016
The UC Davis Clinical and Translational Science Center (CTSC) and the wide array of services that have supported innovative biomedical research and led to the development of new treatments for diseases during the past 10 years will continue, thanks to a $27.8 million grant from the National Center for Accelerating Translational Science and the ongoing support from the School of Medicine.
July 5, 2016
The London-based LouLou Foundation, in partnership with the Orphan Disease Center of the Perelman School of Medicine at the University of Pennsylvania, has awarded a grant to UC Davis Institute for Regenerative Cures Director Jan Nolta and one of the institute’s post-doctoral fellows, Kyle Fink, to study how Fink’s gene editing techniques might be used to treat a rare genetic disorder that hits children – mainly girls – at a very young age with difficult-to-control seizures and severe neuro-developmental impairment.