UC Davis research news releases
February 23, 2015
Undocumented farmworkers are half as likely as those who are documented to use Medicaid, the federal health insurance program available to low-income individuals and families, according to a new study from UC Davis Health System.
February 20, 2015
Hispanics tend to develop alcoholic liver disease (ALD) — a common cause of liver-disease deaths in the U.S. — between four and 12 years earlier than non-Hispanic Caucasians or African Americans, according to a UC Davis Health System study.
February 10, 2015
A new compound discovered by a team of UC Davis investigators has potent actions against production of a chemical that is implicated in the development of chronic pain following a peripheral nerve injury in the spinal cord.
February 4, 2015
An information sheet for women being treated for severe acne improves understanding of contraceptive effectiveness and ways to avoid pregnancy and medication-induced birth defects, a study published today in JAMA Dermatology has found.
Nerve regeneration therapy has potential to prevent arrhythmias, sudden cardiac death after heart attack
February 2, 2015
A therapy currently under development for spinal cord injuries has been shown to stimulate nerve regeneration in the heart and provide resistance to arrhythmias following a heart attack, according to a new study published today in the journal Nature Communications.
UC Davis scientists awarded nearly $4 million for technology in vascular disease treatment and bone and cartilage repair
February 2, 2015
The California Institute for Regenerative Medicine (CIRM) has awarded a pair of $1.8 million grants to two UC Davis scientists to develop better tools for enabling physicians to assess the safety and efficacy of bioengineered tissues used to treat cardiovascular disease and bone and cartilage repair.
January 28, 2015
Ten months after California legislators enacted a controversial law mandating that radiologists notify women if they have dense breast tissue, UC Davis researchers have found that half of primary care physicians are still unfamiliar with the law and many don’t feel comfortable answering breast density-related questions from patients.
Institute for Population Health Improvement recruits California-based labs for no-cost mapping services
January 21, 2015
The UC Davis Institute for Population Health Improvement (IPHI) is recruiting California-based labs to participate in the Laboratory Mapping Assistance Project (Lab MAP). Participating labs will receive free code mapping to convert proprietary order, result and observation codes to standard codes, namely the Logical Observation Identifiers Names and Codes (LOINC) and Systematized Nomenclature of Medicine — Clinical Terms (SNOMED CT®) terminologies.
January 21, 2015
UC Davis professor Moon Chen’s research on the under-representation of minorities in clinical trials appears in the American Society in Clinical Oncology (ASCO)’s annual cancer progress report released Tuesday.
January 20, 2015
Historically known as heroes who put people back together after accidents, trauma surgeons today perform a broad array of surgical procedures, are involved in planning patient care and treat patients at hospital bedsides in addition to operating rooms, a UC Davis Health System study has found.
January 15, 2015
A new device that can rapidly concentrate and extract young cells from irrigation fluid used during orthopaedic surgery holds promise for improving the delivery of stem cell therapy in cases of non-healing fractures.
UC Davis nursing professor increases Spanish health-care knowledge and confidence in graduate students
January 12, 2015
A Betty Irene Moore School of Nursing at UC Davis faculty member received the Provost Hybrid Course Award for a course designed to educate clinical graduate students in Spanish health terminology.
Aubyn Stahmer, expert in translating autism research into community practice, joins UC Davis MIND Institute
January 8, 2015
Aubyn Stahmer, an expert in the translation of evidence-based autism research to community-based practice and delivery, has joined the UC Davis MIND Institute as an associate professor in the Department of Psychiatry and Behavioral Sciences.
January 7, 2015
Patients started on prescription painkillers who have substance-use disorders or who frequently contact their doctors’ offices are at greater risk of having their medication doses increase early in therapy, also increasing their risk of opioid-related overdose or death, UC Davis Health System researchers have found.
December 22, 2014
Using modified human stem cells, a team of UC Davis scientists has developed an improved gene therapy strategy that in animal models shows promise as a functional cure for the human immunodeficiency virus (HIV) that causes AIDS. The achievement, which involves an improved technique to purify populations of HIV-resistant stem cells, opens the door for human clinical trials that were recently approved by the U.S. Food and Drug Administration.
Study funded on the clinical, financial effectiveness of telemedicine versus telephone consultations
December 16, 2014
The U.S. Department of Health and Human Services has awarded a $1,198,384 grant to UC Davis pediatrician James Marcin to investigate how telemedicine consultations in emergency departments impact clinical outcomes, including cost effectiveness, compared with telephone consultations.
December 16, 2014
While the overall death rate from firearm violence has remained unchanged for more than a decade, the patterns for suicide and homicide have changed dramatically, a UC Davis study on the epidemiology of gun violence from 2003 to 2012 has found. The study posted online in the Annual Review of Public Health on Dec. 12 and will appear in the print edition in January.
December 15, 2014
Scientists have long known the p53 protein suppresses tumors. However, a recent animal study by UC Davis researchers has uncovered a complicated relationship between p53 and another protein, Rbm38, highlighting how the body calibrates protein levels. Too much Rbm38 reduces p53 levels, increasing the risk of cancer. Too little Rbm38 allows p53 overexpression, causing premature aging. The study was published in the journal PNAS on Dec. 15.
December 8, 2014
Children with autism spectrum disorder (ASD) were more than twice as likely to have been exposed in utero to preeclampsia, and the likelihood of an autism diagnosis was even greater if the mother experienced more severe disease, a large study by researchers with the UC Davis MIND Institute has found.
December 3, 2014
Hundreds of participants in UC Davis MIND Institute research and their families will head into the woods to “Explore the Great Outdoors” during its 12th Annual Thank You Party on Saturday, Dec. 6, from 1 to 4 p.m. The party is held to thank the children, adolescents, adults and their families who make the MIND Institute's groundbreaking research into autism and other neurodevelopmental conditions possible.
November 27, 2014
More than 100 scientists, including a team of UC Davis molecular biologists, have sequenced the genomes of 16 Anopheles mosquito species to help define the characteristics that make some of them uniquely capable of transmitting malaria parasites to humans.
November 13, 2014
Researchers at UC Davis and other institutions have found that diets rich in whole walnuts or walnut oil slowed prostate cancer growth in mice. In addition, both walnuts and walnut oil reduced cholesterol and increased insulin sensitivity.
November 12, 2014
This week’s issue of the New England Journal of Medicine features an article that highlights an unprecedented analysis of the nation’s childhood head injuries.
November 12, 2014
In its first clinical application in pediatric patients, an investigational medication developed and manufactured at UC Davis has been found to effectively treat children with life-threatening and difficult-to-control epileptic seizures without side effects, according to a research report by scientists at UC Davis and Northwestern University.
November 10, 2014
UC Davis Medical Center is preparing to screen seniors on Medicare who meet the criteria for lung cancer screening using low-dose computed tomography (CT).
October 31, 2014
Treatment for early stage breast cancer is highly effective, and for many women considering treatment choices, chemotherapy may add little to an already high long-term survival rate. Joy Melnikow, professor in the Department of Family and Community Medicine and Director of the Center for Healthcare Policy and Research at UC Davis, is working to define the potential long-term harms of chemotherapy for these patients, so they can be weighed against the potential benefits.
UC Davis MIND Institute researchers to establish new tests to evaluate cognitive growth in people with intellectual disability
October 30, 2014
Researchers with the UC Davis MIND Institute will develop and evaluate tests designed to measure and track changes in the cognitive functioning of people who typically are difficult to assess accurately: those with an intellectual disability, formerly termed mental retardation. The research will be funded through a new, five-year, $3.2 million grant from the National Institutes of Health (NIH).
October 28, 2014
The National Cancer Institute (NCI) has awarded a $2.7 million grant to UC Davis researchers to investigate how the so-called Western diet, which is high in fat and sugar, increases the risk of developing liver and gastrointestinal (GI) cancers. In addition, the researchers will study whether bifidobacteria, a common family of bacteria in the human gut, can be enriched to prevent cancer.
October 27, 2014
A team of UC Davis scientists has found that administering a small molecule – purmorphamine – in animal models after a stroke results in multiple protective effects, including reducing the size of the stroke, decreasing inflammation and increasing markers for nerve regeneration.
October 24, 2014
Researchers at UC Davis have found that the drug bortezomib effectively treats chronic graft-versus-host disease (GVHD), a common and debilitating side effect from allogeneic hematopoietic stem cell transplants.
October 24, 2014
The American Academy on Communication in Healthcare (AACH) has recognized Richard Kravitz, professor of internal medicine, with its George Engel Award. The award is presented annually for outstanding research contributing to the theory, practice and teaching of effective health-care communication and related skills.
October 20, 2014
Researchers at the University of California, Davis, Lawrence Berkeley National Laboratory and Marine Biological Laboratory in Woods Hole, Massachusetts, have created a cellular probe that combines a tarantula toxin with a fluorescent compound to help scientists observe electrical activity in neurons and other cells. The probe binds to a voltage-activated potassium ion channel subtype, lighting up when the channel is turned off and dimming when it is activated.
October 10, 2014
A multidisciplinary team at UC Davis will embark on research to determine whether combining a novel type of immunotherapy with radiation and chemotherapy can make treatment for sarcoma, breast and pancreatic cancers more effective.
October 10, 2014
A team of UC Davis and University of Arizona researchers discovered that adding the bacteria Bifidobacterium longum subsp. infantis (B. infantis) to formula fed to newborn rats reduced the incidence of necrotizing enterocolitis, an often deadly intestinal infection.
MIND Institute receives $900,000 grant to study use of sertraline in young children with autism spectrum disorder
October 8, 2014
Focusing on treatments to ameliorate autism symptoms, researchers with the UC Davis MIND Institute will launch the first study to examine the effectiveness of the use of sertraline, commonly known as Zoloft®™, in children as young as 2 to 6 years, through a three-year, $900,000 grant from the U.S. Health Resources and Services Administration (HRSA).
October 6, 2014
How alterations in a single gene on the X chromosome affects neurological and psychological functioning in men as they age is the subject of a new study by UC Davis MIND Institute researchers.
September 30, 2014
Two UC Davis research teams developing transformational technologies to understand the dynamics of the neural circuitry underlying behavior and cognition have received awards from the federal Brain Research through Advancing Innovative Technologies (BRAIN) Initiative, a presidential grand Challenge enterprise.
September 24, 2014
The UC Davis Comprehensive Cancer Center’s Brain Innovation Group has received a grant from the National Cancer Institute (NCI) to improve brain cancer surgery and treatment using UC Davis-developed biophotonic technology.
September 23, 2014
A 2004 California law mandating specific nurse-to-patient staffing standards in acute care hospitals significantly lowered job-related injuries and illnesses for both registered nurses and licensed practical nurses, according to a UC Davis study published online in the International Archives of Occupational and Environmental Health.
September 21, 2014
Mothers of children with autism are significantly less likely to report taking iron supplements before and during their pregnancies than the mothers of children who are developing normally, a study by researchers with the UC Davis MIND Institute has found.
September 12, 2014
In what may be the largest study of sleep problems among individuals with multiple sclerosis (MS), researchers at UC Davis have found that widely undiagnosed sleep disorders may be at the root of the most common and disabling symptom of the disease: fatigue.
September 11, 2014
Noriko Satake, UC Davis pediatric oncologist and researcher, has demonstrated in laboratory studies that a new, targeted treatment for leukemia is effective.
September 8, 2014
Treatment at the earliest age when signs of autism spectrum disorder (ASD) appear – sometimes in infants as young as 6 months old – significantly reduces symptoms so that, by age 3, most who received the therapy had neither ASD nor developmental delay, a UC Davis MIND Institute research study has found. [español]
September 3, 2014
Infant rhesus monkeys receiving different diets early in life develop distinct immune systems that persist months after weaning, a study by researchers from UC Davis, the California National Primate Research Center (CNPRC) at UC Davis and UC San Francisco has shown. The study, which compares breast- and bottle-fed infants, appears online September 3 in Science Translational Medicine. [en español]
September 2, 2014
Short questionnaires used to identify patients at risk for depression are linked with antidepressant medications being prescribed when they may not be needed, according to new research from UC Davis Health System published in the September-October issue of the Journal of the American Board of Family Medicine.
August 29, 2014
Researchers at UC Davis have made some surprising discoveries about the body’s initial responses to HIV infection. Studying simian immunodeficiency virus (SIV), the team found that specialized cells in the intestine called Paneth cells are early responders to viral invasion and are the source of gut inflammation by producing a cytokine called interleukin-1 beta (IL-1β).
August 28, 2014
Autism is far more common in boys than girls - affecting 1 in 54 boys and 1 in 252 girls — but little is known about biological differences between boys and girls with autism. A new study, called the ‘Girls with Autism — Imaging of Neurodevelopment’ or GAIN Study, led by researchers at the UC Davis MIND Institute will explore those differences in very young girls with autism.
August 26, 2014
mKit Lam and colleagues from UC Davis and other institutions have created dynamic nanoparticles (NPs) that could provide an arsenal of applications to diagnose and treat cancer. Built on an easy-to-make polymer, these particles can be used as contrast agents to light up tumors for MRI and PET scans or deliver chemo and other therapies to destroy tumors. In addition, the particles are biocompatible and have shown no toxicity. The study was published online today in Nature Communications.
August 13, 2014
Bringing together the research prowess of the University of California to address the increase in autism incidence, its public health impacts, and the need to speed the development of treatments for affected individuals and their families, internationally respected scientists from UC campuses at Irvine, Los Angeles, San Diego, San Francisco and Davis will converge at the UC Davis MIND Institute for a daylong summit on innovative translational neurodevelopmental research.
August 11, 2014
Researchers at UC Davis, City of Hope, Taipai Medical University and National Health Research Institutes in Taiwan have discovered how a drug that deprives the cells of a key amino acid specifically kills cancer cells.
August 7, 2014
UC Davis Comprehensive Cancer Center oncologist Chong-Xian Pan has received a $650,000 grant from the VA Northern California Health Care System to conduct the first clinical trial of a novel chemotherapy-delivery drug he developed for bladder cancer patients.
August 6, 2014
Lin Tian’s fascination with neuroscience stems from a deep curiosity about the complexity and elegance of the human brain. As one of only five scientists in the U.S. and Canada — and the first at UC Davis —to be named a 2014 Rita Allen Foundation Scholar, Tian will be developing optical sensors and applications to acquire fundamental insights about how the nervous system functions in health and disease.
August 5, 2014
Founding Dean for the Betty Irene Moore School of Nursing at UC Davis, Heather M. Young, was recently named the 2014 recipient of the Doris Schwartz Gerontological Nursing Research Award by the nation’s largest interdisciplinary organization devoted to the field of aging — the Gerontological Society of America (GSA).
UC Davis nursing school approved for $2.1 million award by the Patient-Centered Outcomes Research Institute
July 31, 2014
A research project led by the Betty Irene Moore School of Nursing at UC Davis was approved for a $2.1 million award by the Patient-Centered Outcomes Research Institute (PCORI) to study improving health for individuals with diabetes.
July 24, 2014
Early life experiences, such as childhood socioeconomic status and literacy, may have greater influence on the risk of cognitive impairment late in life than such demographic characteristics as race and ethnicity, a large study by researchers with the UC Davis Alzheimer’s Disease Center and the University of Victoria, Canada, has found.
July 24, 2014
While having children or being female is often thought to be linked with the decision to leave a general surgery residency, this is not true, according to a 10-year evaluation of UC Davis residents.
UC Davis study researches potential link to care for mothers battling depression: their child's pediatrician
July 21, 2014
Pediatricians will screen mothers for depression in a new research study conducted at UC Davis Children's Hospital. The grant is funded by the National Institute of Mental Health.
July 18, 2014
UC Davis MIND Institute researchers are seeking participants for a new study that will examine the early development of infants who have an older sibling with autism spectrum disorder, attention-deficit/hyperactivity disorder (ADHD), or who are developing typically. In an effort to detect the earliest signs of developmental problems, the researchers will test a new online screening measure that uses videos to help parents track their infants’ development.
July 18, 2014
No Stomach for Cancer Foundation (NSFC) has awarded cancer geneticist Luis Carvajal-Carmona a $50,000 grant to study the genetic characteristics of gastric cancer.
July 18, 2014
Researchers from UC Davis School of Medicine and Shriners Hospitals for Children – Northern California have identified a group of cells in the brain that they say plays an important role in the abnormal neuron development in Down syndrome.
July 17, 2014
The current system used to determine Medicare payments for surgeries — called relative value units, or RVUs — poorly correlates with the actual work involved in procedures, new research from UC Davis has found. The authors of the study, which will be published in the August issue of the Journal of Surgical Research, call for a more objective system for determining the value of work done by surgeons.
July 15, 2014
Researchers at UC Davis School of Medicine have for the first time shown that a polysialylated glycoprotein that regulates neurodevelopment exists on the surface of cells in the adult inner ear.
July 14, 2014
The Hartwell Foundation has presented an Individual Biomedical Research Award to Professor Judy A. Van de Water of the University of California, Davis, recognizing research that could affect nearly one in every four cases of autism among children in the U.S.
July 14, 2014
Researchers at UC Davis, University of Massachusetts and Harvard Medical School have created a combination drug that controls both tumor growth and metastasis. By combining a COX-2 inhibitor, similar to Celebrex, and an epoxide hydrolase (sEH) inhibitor, the drug controls angiogenesis (blood vessel formation), limiting a tumor’s ability to grow and spread. The study appears today in the journal Proceedings of the National Academy of Sciences.
July 10, 2014
When it comes to a specific type of pancreatic surgery, post-operative complications have a far greater impact on total cost than does how long the patient stays in the hospital, according to a published paper by UC Davis researchers.
July 7, 2014
A nationwide study of more than 40,000 children evaluated in hospital emergency departments for head trauma found that if children had only loss of consciousness, and no other signs or symptoms related to the head trauma, they are very unlikely to have sustained serious brain injuries. Children who have only isolated loss of consciousness after head trauma do not routinely require computed tomography (CT) scans of the head, reported researchers from UC Davis Health System and Boston Children’s Hospital.
July 2, 2014
A potentially groundbreaking investigational drug designed to treat the painful vaso-occlusive crises that are the hallmark of sickle cell disease has been found to be safe following a clinical trial at UC Davis.
June 26, 2014
Researchers at UC Davis have determined that surgical biopsies can be safely performed on select patients with late-stage non-small cell lung cancer, which should enhance their access to drugs that target specific genetic mutations such as epidermal growth factor receptor (EGFR).
June 24, 2014
A UC Davis program designed to better manage cancer patients taking oral chemotherapy drugs has demonstrated that one-on-one counseling, education and monitoring can improve adherence to potentially life-saving cancer treatments.
UC Davis MIND Institute study finds association between maternal exposure to agricultural pesticides, autism in offspring
June 22, 2014
Pregnant women who lived in close proximity to fields and farms where chemical pesticides were applied experienced a two-thirds increased risk of having a child with autism spectrum disorder or other developmental delay, a study by researchers with the UC Davis MIND Institute has found. The associations were stronger when the exposures occurred during the second and third trimesters of the women’s pregnancies. [en español]
June 16, 2014
UC Davis Comprehensive Cancer Center patients will soon be part of an unprecedented clinical trial designed to improve access to promising therapies and speed development of effective treatments for an advanced form of lung cancer, the leading cancer killer of both men and women.
June 11, 2014
In a remarkable series of experiments on a fungus that causes cryptococcal meningitis, a deadly infection of the membranes that cover the spinal cord and brain, investigators at UC Davis have isolated a protein that appears to be responsible for the fungus’ ability to cross from the bloodstream into the brain.
June 10, 2014
A UC Davis study comparing violent misdemeanor convictions with their original criminal charges has found that subsequent violent crimes could be prevented if criminal charges were reduced less often during plea bargaining.
May 30, 2014
Devices made of metal plates and screws that can precisely align and stabilize fractured bones as they heal can safely and effectively repair the sternum, according to a review of UC Davis surgeries published in the May issue of the Annals of Plastic Surgery.
May 29, 2014
Paramita Ghosh, a UC Davis associate professor and expert in signal transduction pathways in prostate cancer, has been selected as one of 350 scientists to work on a project that aims to reduce public exposure to environmental agents that can lead to cancer and that hopes to inspire research into multi-faceted approaches to cancer prevention, treatment and prolonged survival.
May 14, 2014
Even if treated, hypertension and high cholesterol are common for people with human immunodeficiency virus (HIV), according to a new study from researchers at Mount Sinai St. Luke’s and Mount Sinai Roosevelt hospitals in New York and the University of California, Davis.
May 12, 2014
Colorectal cancer screening saves lives, but too few people get tested. In an effort to increase these numbers,researchers from UC Davis and elsewhere investigated whether an individualized interactive multimedia computer program (IMCP) would spur patients to get screened.
May 8, 2014
Children with autism experience deficits in a type of immune cell that protects the body from infection. Called granulocytes, the cells exhibit one-third the capacity to fight infection and protect the body from invasion compared to the same cells in children who are developing normally.
April 30, 2014
The five University of California medical centers and their affiliates participating in the Athena Breast Health Network are using a new guide for sharing electronic data for breast cancer treatment. Developed by the American Society of Clinical Oncology (ASCO) and approved through ASCO's Health Level Seven International committee (HL7), the guide will become a national data exchange standard. With the guide, Athena can utilize structured data capture tools for coordination of care, registry submission and research.
April 28, 2014
The stress hormone epinephrine – the source of the “fight-or-flight” response – also heightens stresses at the cellular level, inhibiting wound healing and promoting a state of chronic inflammation that prohibits the body’s stem cells from migrating to a wound to encourage skin regeneration, UC Davis researchers have found.
April 22, 2014
Researchers at UC Davis Children’s Hospital have shown that children with Down syndrome have significantly better in-hospital survival rates after surgeries for congenital heart disease (CHD) than their genetically typical peers.
April 22, 2014
The risk of pregnancy among women using a newer method of planned sterilization called hysteroscopic sterilization is more than 10 times greater over a10-year period than using more commonly performed laparoscopic sterilization, a study by researchers with Yale University and UC Davis has found.
April 17, 2014
Researchers at UC Davis have identified a new feature of the genetic mutation responsible for the progressive neurodegenerative disorder, fragile X-associated tremor/ataxia syndrome (FXTAS) — the formation of “R-loops,” which they believe may be associated with the disorder’s neurological symptoms, such as tremors, lack of balance, features of parkinsonism, and cognitive decline.
April 17, 2014
An international team led by researchers at UC Davis has shown that the cyclin B1/Cdk1 protein complex, which plays a key role in cell division, also boosts the mitochondrial activity to power that process. This is the first time the complex has been shown to perform both jobs. This newfound ability could make cyclin B1/Cdk1 an excellent target to control cellular energy production, potentially advancing cancer care and regenerative medicine. The research was published online today in the journal Developmental Cell.
April 14, 2014
Prenatal exposure to selective serotonin reuptake inhibitors (SSRIs), medications frequently prescribed to treat depression, anxiety and other mental-health disorders, is associated with a higher incidence of autism spectrum disorder (ASD) and developmental delays (DD) in male children, a study of nearly 1,000 mother-child pairs has found.
April 8, 2014
Federal agencies responsible for tracking workplace hazards fail to report 77 percent of the injuries and illnesses of U.S. agricultural workers and farmers, new research from UC Davis has found. [en español]
April 7, 2014
A multidisciplinary research team at UC Davis has found a key biological trigger — a protein known as nitric oxide synthase, or NOS — that makes the heart beat stronger in response to higher blood pressure, along with a way to turn that trigger off when it becomes overactive.
April 3, 2014
Jesse De La Cruz didn’t have any hepatitis C symptoms for nearly 15 years. Physicians say that’s fairly typical of an illness also known as “the silent killer.”
April 2, 2014
The very earliest signs of a debilitating neurodegenerative disorder, in which physical symptoms are not apparent until the fifth decade of life, are detectable in individuals as young as 30 years old using a new, sophisticated type of neuroimaging, researchers at UC Davis, the University of Illinois and UCLA have found.