UC Davis research news releases
April 17, 2018
Researchers at the UC Davis MIND Institute have found that children with autism spectrum disorder (ASD) have reduced immune system regulation, as well as shifts in their gut microbiota. The immune deregulation appears to facilitate increased inflammation and may be linked to the gastrointestinal issues so often experienced by children with ASD. The research was published in the journal Brain, Behavior, and Immunity.
April 13, 2018
The inauigural Heart Research Day is Wednesday, April 18, from 8 a.m. until 5 p.m. in the Education Building lecture hall 1222. Register online at https://goo.gl/W2Tj71
Study does not find change in firearm homicide or suicide rates through 2008 after repeal of comprehensive background check laws in two states
April 4, 2018
A study of firearm homicide and suicide rates in the 10 years after two states repealed their comprehensive background check laws in 1998 found no change in the rates of either cause of death from firearms through 2008. The repeals eliminated background check requirements for private-party transfers, but not for firearm transfers from licensed dealers.
March 20, 2018
In a striking new finding, researchers at the UC Davis MIND Institute found that typically-developing children gain more neurons in a region of the brain that governs social and emotional behavior, the amygdala, as they become adults. This phenomenon does not happen in people with autism spectrum disorder (ASD). Instead, children with ASD have too many neurons early on and then appear to lose those neurons as they become adults. The findings were published today in the journal Proceedings of the National Academy of Sciences (PNAS).
March 15, 2018
The Spanish version of a questionnaire used to assess the speech and quality-of- life of children and young adults following cleft-palate surgery has been developed by craniofacial disorder specialists at UC Davis Health and the University of Utah.
March 8, 2018
Researchers at UC Davis have shown that patients with acute myeloid leukemia (AML) who received their care at a National Cancer Institute (NCI) cancer center in California had a dramatically reduced risk of early mortality. Using data from the California Cancer Registry and the Patient Discharge Dataset, the team determined that the risk was reduced by 53 percent. These findings were reported in February in the journal Cancer.
March 7, 2018
Researchers at UC Davis Health, together with colleagues at UC San Francisco and the University of North Carolina at Chapel Hill, have found a mechanism for making HIV come out of hiding and become susceptible to anti-HIV drugs. Their study is now published in The Journal of Clinical Investigation.
March 6, 2018
Researchers at UC Davis Health and Albany Medical College have shown that the protein vascular endothelial growth factor A — or VEGFA — plays a major role in the inflammation and airway obstruction associated with asthma. The finding may eventually lead to new asthma treatments targeting VEGFA.
February 28, 2018
Lower-wage workers who receive a $1 raise call in sick less and consider themselves healthier than those who do not, new UC Davis research on minimum-wage policies shows.
February 16, 2018
For the first time, UC Davis School of Medicine has ranked in the top 20 percent of institutions in the country for research funding from the National Institutes of Health (NIH).
February 14, 2018
Angela Haczku, a leading researcher on environmental causes for airway inflammation, will receive more than $900,000 from the Tobacco Related-Disease Research Program to study chronic obstructive pulmonary disease (COPD) and ozone, a toxic component of urban smog.
February 9, 2018
Adolescent and young adult cancer survivors who are African American, poor or have public or no health insurance are far more likely to suffer from coronary artery disease, heart failure or stroke later in life than non-Hispanic white cancer survivors.
February 6, 2018
UC Davis Health is hosting the National Institutes of Health’s All of Us Journey, a traveling, hands-on exhibit to raise awareness about precision medicine and the All of Us research program.
February 5, 2018
UC Davis public health researchers are conducting a comprehensive assessment of the health effects of the Northern California fires in October. They are asking one person per household in Napa, Sonoma and other counties affected by the fires to answer an online questionnaire — called the UC Davis Northern California Fire and Health Impacts Survey — about their daily lives, property and health before the fires occurred and immediately afterward, along with their current situations.
February 5, 2018
After years of investigation, researchers at UC Davis, Johns Hopkins, and the National Institute of Allergy and Infectious Diseases have discovered how the immune system might protect a person from recurrent bacterial skin infections caused by Staphylococcus aureus (staph). The findings, publishing online this week in The Journal of Clinical Investigation, open new doors to someday developing vaccines to prevent staph skin infections, which account for 14 million outpatient visits, nearly 500,000 hospital admissions and $3 billion to $4 billion in inpatient health care costs in the U.S. per year.
January 31, 2018
A new congressionally mandated report from the National Academies of Sciences, Engineering, and Medicine released today has concluded that there is a substantial unmet need for mental health services among veterans of the recent wars in Afghanistan and Iraq.
January 25, 2018
Efrain Talamantes, an assistant professor of internal medicine and an expert in advancing equity and diversity in the field of medicine, has been named an Emerging Scholar for 2018 by the publication Diverse: Issues in Higher Education.
Researchers say medical licensing test should include more prescription drug safety, misuse questions
January 24, 2018
Research led by experts from the UC Davis schools of medicine and nursing has identified gaps in pain-related education for health care providers that leave out important aspects of safe and effective pain management competencies, including those specific to opioid safety. These findings, said the researchers, may help explain one reason for the current public health crisis of inappropriate pain management and prescription drug abuse.
January 23, 2018
When fires ripped through suburban subdivisions in Santa Rosa last October, they may have done more than reduce homes to ashes. By incinerating all kinds of materials — insulation, electronics, furniture, cleaning products, pesticides — at very high temperatures, they could have created unknown or previously unrecognized health hazards in the smoke and ash. Researchers from the University of California, Davis, are trying to figure out just what is in that ash and air.
January 3, 2018
In a commentary published today in the New England Journal of Medicine, UC Davis researcher William Murphy expressed cautious optimism about efforts to genetically engineer hematopoietic stem cells (HSCs) to temporarily resist cell death during transplantation. While these gene therapy approaches could dramatically improve patient outcomes, Murphy argues that their risks must be carefully studied in diverse animal models.
December 28, 2017
Ophthalmologists’ use of electronic health records (EHR) systems for storing and accessing patients’ medical histories more than doubled between 2006 and 2016, while their perceptions of financial and clinical productivity following EHR implementation declined, a study published today in JAMA Ophthalmology shows.
December 21, 2017
A team of UC Davis investigators has been awarded a $1.2 million grant to examine a common virus and its effects on immune system function after stem cell transplantation.
December 19, 2017
Human and veterinary researchers at UC Davis and other institutions have shown that enhanced natural killer (NK) immune cells, combined with radiation therapy, can be effective against spontaneous osteosarcoma (bone cancer) in dogs. The research showed these NK cells homed in on cancer and reduced metastasis in the treated dogs, offering a potential immunotherapy against solid tumors. The study was published today in the Journal for Immunotherapy of Cancer.
December 14, 2017
A study assessing the impact of medical marijuana laws (MML) on adolescent substance use has found decreased use of all substances among 8th graders, no change among 10th graders and increased non-medical use of prescription opioids and cigarette use among 12th graders, following MML enactment.
December 14, 2017
About half of new moms in California, including those with diabetes, do not receive critical follow-up care within three months after giving birth, a new study published in the December issue of the journal Contraception shows.
December 4, 2017
A microscope using ultraviolet light to illuminate samples enables pathologists to assess high-resolution images of biopsies and other fresh tissue samples for disease within minutes, without requiring the time-consuming preparation of conventional slides or destroying the tissue.
Statewide survey finds physicians, pharmacists comply with prescription drug monitoring registration. Next step: increase use
November 29, 2017
A state law that funded upgrades to California’s prescription drug monitoring program and mandated physicians, pharmacists and controlled substance prescribers to register by July 2016 significantly increased registration rates, a new survey of 1,904 California physicians and pharmacists conducted by the UC Davis Violence Prevention Program has found.
November 27, 2017
Patients who ask for specialist referrals, laboratory tests or certain medications and don’t get them tend to be less satisfied with their doctors than those whose requests are fulfilled, new research from UC Davis Health shows. Based on the results, the study authors recommend communications training for physicians that fosters positive experiences for patients without agreeing to all requests for particular diagnostics or treatments.
November 27, 2017
A large, multi-center, international study to assess the long-term benefits of glucocorticoid treatment for Duchenne muscular dystrophy (DMD) concludes that it does preserve muscle strength and function as well as reduce the risk of death for patients.
November 21, 2017
The medical school interview – a key determinant in the admissions process and, ultimately, in the physician workforce – appears to skew for or against applicants depending on their age, gender and self-identified disadvantaged socioeconomic status.
November 20, 2017
UC Davis MIND Institute esearchers have shown in a mouse model that an elevated maternal immune response changes the epigenetic landscape in offspring’s microglia, immune cells found in the brain and spinal cord. These changes affect genes associated with immune signaling and neural development, some of which have been implicated in autism spectrum disorder (ASD). The study was published online in the journal Glia.
November 17, 2017
Giving bad news is never easy, especially when it’s life or death. But when an oncologist delivers a poor prognosis to a cancer patient, does it harm their relationship? Some research studies have suggested it can.
November 7, 2017
For many, breast cancer is more than just a disease – it’s personal. One in eight women will be diagnosed with breast cancer at some point in their lives. But through new discoveries at the genetic level, the personal nature of cancer will eventually be what helps to beat it.
October 25, 2017
Participating in a brief intervention delivered by their peers in community settings can help reduce smoking among youth and young adults, a new study from a team of tobacco-cessation researchers shows.
October 23, 2017
Research conducted in mice at the UC Davis MIND Institute suggests that a drug treatment can reverse cognitive deficits and social abnormalities in a rare genetic disorder, 16p11.2 deletion syndrome, which includes symptoms of intellectual disability and autism spectrum disorder, among others. Results of parallel studies conducted at the MIND and at the Massachusetts Institute of Technology Picower Institute for Learning and Memory appear in the latest issue of the journal Neuropsychopharmacology.
October 20, 2017
UC Davis has received its first National Cancer Institute (NCI) Moonshot grant ̶ $2.5 million over five years ̶ to explore immunotherapy treatments for dogs who develop melanoma and osteosarcoma and that may one day benefit humans, as well.
October 19, 2017
Members of the UC Davis Comprehensive Cancer Center lung cancer treatment team will present at WCLC 2017, a one-day conference on Saturday, Nov. 11, from 7 a.m. to 4 p.m. in San Francisco. Presenters will share the latest lung cancer and other thoracic malignancy advances highlighted at the recent 18th Annual World Conference on Lung Cancer in Japan.
October 9, 2017
Of the three states that recently expanded comprehensive background check (CBC) policies to include all gun transfers, including those among private parties, only Delaware showed an overall increase in firearm background checks. Washington and Colorado had no changes, which the study authors say suggests that compliance and enforcement were incomplete.
October 6, 2017
Assistant Professor Sean Collins, Department of Microbiology and Molecular Genetics, has received a $1.5 million award from the National Institutes of Health to advance the development of “smart” immune cells for therapies to treat cancer and other diseases. The five-year NIH Director’s New Innovator Award aims to provide new insight into how to engineer immune cells to control their recruitment and response to tumors.
September 28, 2017
The California Institute for Regenerative Medicine today awarded a nearly $8 million grant to University of California, Davis, stem cell researchers to launch a special clinical trials program in Sacramento to accelerate the therapeutic development and delivery of stem cell therapies in human patients.
September 27, 2017
UC Davis researchers, led by Julie Sutcliffe, have received a $3.3 million grant from the National Institutes of Health to advance efforts to diagnose pancreatic cancer before it spreads.
September 25, 2017
How do fire-suppression chemicals and pesticides affect wildfire smoke and the health of those who breathe it? UC Davis graduate students discovered that this question cannot be answered based on current scientific evidence and, in a review published in Current Topics in Toxicology, they recommend more studies on the compounds in wildfire smoke.
September 7, 2017
The UC Davis MIND Institute has been awarded a 5-year, $12 million Autism Centers of Excellence (ACE) grant, one of five in the nation, to create a “Center for the Development of Phenotype-based Treatments of Autism Spectrum Disorder.”
August 30, 2017
UC Davis stem cell scientist Paul Knoepfler has been awarded a second $250,000 grant for glioma research from an organization begun 15 years ago by a 5-year-old girl with a deadly form of childhood cancer.
August 24, 2017
A pair of English bulldog puppies are the first patients to be successfully treated with a unique therapy — a combination of surgery and stem cells — developed at the University of California, Davis, to help preserve lower-limb function in children with spina bifida.
August 18, 2017
UC Davis researchers have shown that radiation therapy before surgery improves overall survival for patients with soft tissue sarcomas. This pre-surgical, or neoadjuvant, radiotherapy allows surgeons to get better margins around tumors and remove even microscopic cancer tissue more often. The study was published recently in the Annals of Surgical Oncology.
August 18, 2017
A review of kidney cancer in California from 1988 through 2013 by the UC Davis Institute for Population Health Improvement (IPHI) has concluded that the high incidence of small tumors and early-stage disease observed in California from 1988 until about 2009 has declined and stabilized in recent years, signaling the end of a trend.
August 11, 2017
Julie Schweitzer, a professor in the Department of Psychiatry and Behavioral Sciences and UC Davis MIND Institute researcher, has received a $3.7 million grant from the National Institute of Mental Health (NIMH) to track impulsivity and self-control in teens and young adults over time.
July 31, 2017
Health plans that collaborated to share best practices and successful strategies for treating patients diagnosed with hypertension saw significant improvement in controlling high blood pressure, a study by the California Department of Health Care Services (DHCS) and UC Davis Institute of Population Health Improvement (IPHI) has found.
July 28, 2017
John Paul Aboubechara, a fifth-year student in the combined M.D./Ph.D. program at UC Davis School of Medicine, has been honored with this year’s Daniel T. O’Connor, M.D., Memorial Research Grant.
July 26, 2017
Sorting out when or whether to get mammograms can be perplexing for any woman, and a health provider’s advice may not settle the matter. That’s because even experts disagree about when screening mammography is appropriate and for whom.
July 25, 2017
The University of California has been awarded a nearly $14.7 million multi-year grant from the National Institutes of Health to study contributors to dementia in the Latino population in the United States. The multicenter study will examine the biological underpinnings of stroke, mild cognitive impairment and Alzheimer’s disease among Hispanics, and pursue new therapeutic directions to reduce brain health disparities.
July 24, 2017
The University of California Firearm Violence Research Center at UC Davis’ Sacramento campus officially launched July 4 under the direction of Garen Wintemute, a professor of emergency medicine and recognized authority on the epidemiology of firearm violence.
July 18, 2017
The results of an international clinical trial, led in part by a UC Davis School of Medicine expert, have shown that a drug therapy for a severe type of muscular dystrophy holds promise for a subgroup of patients.
July 14, 2017
The Society for Academic Emergency Medicine (SAEM) recently honored Nate Kuppermann with more than just a lifetime award for meritorious accomplishments in research and mentorship.
July 12, 2017
A new study published today in The American Journal of Pathologyfound that mice fed a high-fat, high-sugar Western diet developed hepatic inflammation, which was more common in males than females and most pronounced in mice that also lacked a bile acid receptor known as farnesoid x receptor, or FXR.
July 11, 2017
In a decisive move by the Governor and Legislature, the University of California Umbilical Cord Blood Collection Program (UCBCP) has been extended through 2022. The program enables mothers of newborns to donate their babies’ umbilical cord blood and have it publicly banked so it is available to anyone for lifesaving transplantations.
July 10, 2017
The Northern California chapter of Huntington’s Disease Society of American (HDSA) has honored UC Davis Health’s Lorin Scher for his outstanding service to the Huntington’s disease community in the Sacramento region.
June 28, 2017
UC Davis Health and the Sacramento City Fire Department have established a research partnership that aims to improve care for sick and injured children during and after an emergency transport.
June 22, 2017
Researchers at the UC Davis MIND Institute and Boston Children’s Hospital have confirmed that mice without the Shank3B protein model aspects of brain physiology and behavioral symptoms observed in people with autism. The findings confirm that Shank3B knockout mice provide a valuable research tool for future efforts to develop new therapies. The study, supported by Autism Speaks, was published in the journal Molecular Autism.
June 22, 2017
The survival rate of U.S. gunshot victims has not shown a marked improvement, as other recent studies have suggested, according to new research from Duke University and the University of California, Davis.
June 13, 2017
Despite evidence showing that the routine use of sonography in hospital emergency departments can safely improve care for adults when evaluating for possible abdominal trauma injuries, researchers at UC Davis Medical Center could not identify any significant improvements in care for pediatric trauma patients.
June 6, 2017
With its internationally renowned school of veterinary medicine and its NCI-designated comprehensive cancer center, UC Davis is uniquely positioned to harness the power of each to tackle one of life’s greatest challenges: cancer.
June 6, 2017
Researchers at UC Davis Health and other institutions have shown that gender differences in mice microbiota can modulate the risk of developing metabolic disease and liver cancer. In addition, the team found that a bile acid receptor protein, called FXR, has a profound impact on mouse microbiota and bile acid profiles and is differentially expressed based on gender. The study was published in the journal Scientific Reports.
May 24, 2017
UC Davis has signed a licensing agreement providing Isotropic Imaging Corporation the rights to commercialize a novel computed tomography (CT) scanner that has the potential to improve breast cancer detection and positively impact women’s health.
May 5, 2017
The UC Davis Neuromuscular Research Center has been recognized as a Certified Duchenne Care Center by Parent Project Muscular Dystrophy for national leadership in treating Duchenne muscular dystrophy.