NEWS | May 7, 2013

UC Davis radiation oncology chief leads development of new prostate cancer guideline


Based on a major effort co-led by UC Davis prostate cancer expert Richard Valicenti, the nation’s leading urological and radiation oncology organizations today announced a new guideline for radiation therapy after prostatectomy.

Dr. Richard Valicenti Dr. Richard Valicenti

The guideline, released jointly by the American Society for Radiation Oncology (ASTRO) and the American Urological Association (AUA), for the first time provides evidence- and consensus-based recommendations about the benefits and risks of additional cancer treatment after prostate-removal surgery.

Valicenti, chair of the UC Davis Department of Radiation Oncology, championed the comprehensive review on behalf of ASTRO. Ian Thompson, director of the Cancer Therapy and Research Center at the University of Texas Health Science Center at San Antonio, led the work on behalf of the AUA. The guideline was based on their analysis of 324 research articles published between 1990 and 2012.

“There is a critical need for evidence-based standards, recommendations and options to maximize our ultimate goal of increased patient survival,” Valicenti said. “I think this guideline gives urologists and radiation oncologists the information, backed by expert opinion, on how to manage patients who have a high risk of recurrence after radical prostatectomies. My hope is that these guidelines will lead to higher overall survival rates and better quality of life for men undergoing radical prostatectomy.”

The guideline focuses on treatment options, as well as assessments and discussions with patients regarding potential side effects of both radical prostatectomy and post-surgical radiation therapy. The guideline includes recommendations for physicians to inform prostate cancer patients when they are at a higher risk for cancer recurrence, when radiation therapy is warranted after prostatectomy, as well as the short- and long-term urinary, bowel and sexual side effects of treatments.

The Adjuvant and Salvage Radiotherapy After Prostatectomy: ASTRO/AUA Guideline will be published in the Aug. 1, 2013, print issue of the International Journal of Radiation Oncology, Biology, Physics (Red Journal), the official journal of ASTRO, and in the August 2013 print issue of The Journal of Urology, the official journal of the AUA.

UC Davis Comprehensive Cancer Center
UC Davis Comprehensive Cancer Center is the only National Cancer Institute-designated center serving the Central Valley and inland Northern California, a region of more than 6 million people. Its specialists provide compassionate, comprehensive care for more than 9,000 adults and children every year, and access to more than 150 clinical trials at any given time. Its innovative research program engages more than 280 scientists at UC Davis, Lawrence Livermore National Laboratory and Jackson Laboratory (JAX West), whose scientific partnerships advance discovery of new tools to diagnose and treat cancer. Through the Cancer Care Network, UC Davis collaborates with a number of hospitals and clinical centers throughout the Central Valley and Northern California regions to offer the latest cancer care. Its community-based outreach and education programs address disparities in cancer outcomes across diverse populations. For more information, visit