April 17, 2014
Researchers at UC Davis have identified a new feature of the genetic mutation responsible for the progressive neurodegenerative disorder, fragile X-associated tremor/ataxia syndrome (FXTAS) — the formation of “R-loops,” which they believe may be associated with the disorder’s neurological symptoms, such as tremors, lack of balance, features of parkinsonism, and cognitive decline.
April 17, 2014
An international team led by researchers at UC Davis has shown that the cyclin B1/Cdk1 protein complex, which plays a key role in cell division, also boosts the mitochondrial activity to power that process. This is the first time the complex has been shown to perform both jobs. This newfound ability could make cyclin B1/Cdk1 an excellent target to control cellular energy production, potentially advancing cancer care and regenerative medicine. The research was published online today in the journal Developmental Cell.
April 14, 2014
Prenatal exposure to selective serotonin reuptake inhibitors (SSRIs), medications frequently prescribed to treat depression, anxiety and other mental-health disorders, is associated with a higher incidence of autism spectrum disorder (ASD) and developmental delays (DD) in male children, a study of nearly 1,000 mother-child pairs has found.
April 8, 2014
Federal agencies responsible for tracking workplace hazards fail to report 77 percent of the injuries and illnesses of U.S. agricultural workers and farmers, new research from UC Davis has found. [en español]
April 7, 2014
A multidisciplinary research team at UC Davis has found a key biological trigger — a protein known as nitric oxide synthase, or NOS — that makes the heart beat stronger in response to higher blood pressure, along with a way to turn that trigger off when it becomes overactive.
April 3, 2014
Jesse De La Cruz didn’t have any hepatitis C symptoms for nearly 15 years. Physicians say that’s fairly typical of an illness also known as “the silent killer.”
April 2, 2014
The very earliest signs of a debilitating neurodegenerative disorder, in which physical symptoms are not apparent until the fifth decade of life, are detectable in individuals as young as 30 years old using a new, sophisticated type of neuroimaging, researchers at UC Davis, the University of Illinois and UCLA have found.
April 1, 2014
A new technology can simultaneously detect as many as 100 clinically important protein molecules in breast tumor cells – a quantum advance over conventional methods that can pinpoint only two to four at the same time. The advantages of the new methodology, called multiplexed ion beam imaging (MIBI), is described by a team of scientists at UC Davis and San Francisco and at Stanford, Genentec in the March 23 advance online publication of the journal Nature Medicine.
March 26, 2014
Blood and tumor specimen collection from cancer patients is critical to research into new, more personally targeted therapies. But biospecimen collection among diverse populations lags far behind that of whites. [Chinese, Vietnamese and Spanish]
March 24, 2014
UC Davis professor Christopher Bowlus of the Division of Gastroenterology and Hepatology, and his liver cancer disparity research, are featured on the Health Equity Research Snapshot of the Association of American Medical Colleges (AAMC).
March 21, 2014
After nine years and countless fund-raising events, the Placer Breast Cancer Endowment on Thursday reached its goal of $1.5 million for breast cancer research at UC Davis Comprehensive Cancer Center.
March 21, 2014
For the first time, scientists have succeeded in coaxing laboratory cultures of human stem cells to develop into the specialized, unique cells needed to repair a patient’s defective or diseased bladder.
March 20, 2014
Researchers at UC Davis have found that the investigational cancer vaccine tecemotide, when administered with the chemotherapeutic cisplatin, boosted immune response and reduced the number of tumors in mice with lung cancer. The study also found that radiation treatments did not significantly impair the immune response. The paper was published on March 10 in the journal Cancer Immunology Research, an American Association for Cancer Research (AACR) publication.
March 19, 2014
UC Davis clinicians and physicists have recommended new strategies to make computed tomography (CT) safer, including adoption of a new metric for dose measurement, ways to manage exposure protocols that differ by CT brand and specific approaches to reduce exposure during needle biopsies. The recommendations are detailed in papers published in the March issue of the Journal of the American College of Radiology (JACR).
March 18, 2014
Twenty years after Congress mandated that research funded by the National Institutes of Health include minorities, less than 5 percent of trials participants are non-white, and less than 2 percent of clinical cancer research studies focus on non-white ethnic or racial groups, UC Davis researchers have found. [Chinese, Spanish, Korean, Vietnamese]
March 18, 2014
A new study involving researchers from UC Davis and four other National Cancer Institute-designated cancer centers reveals important barriers that limit minority group participation in cancer clinical trials, findings that will be used to refine and launch more effective strategies to assure that more minorities benefit from clinical trials.
March 17, 2014
Mothers of newborns can now donate their babies’ umbilical cord blood at UC Davis Medical Center and other hospitals throughout the state as part of California’s first comprehensive public system of collecting cord blood for lifesaving transplantations and medical research. [en español]
March 14, 2014
UC Davis researchers have found that routine information — blood pressure, respiratory rate, temperature and white blood cell count — from the electronic health records (EHRs) of hospitalized patients can be used to predict the early stages of sepsis, a leading cause of death and hospitalization in the U.S. They also determined that just three measures — lactate level, blood pressure and respiratory rate — can pinpoint the likelihood that a patient will die from the disease.
March 14, 2014
Several chemotherapy patients at the UC Davis Comprehensive Cancer Center will be invited to use tablets with a unique social networking tool as part of their treatment plan.
March 12, 2014
Microbes collected from Northern California and throughout the nation will soon blast into orbit for research and a microgravity growth competition on the International Space Station (ISS). This citizen science project, known as Project MERCCURI, is led in part by UC Davis microbiologists, who are investigating how microbes from different places on Earth compare to each other and to those found on the International Space Station.
March 11, 2014
The UC Davis MIND Institute has been named an Intellectual and Developmental Disabilities Research Center (IDDRC), through a prestigious grant from the Eunice Kennedy Shriver National Institute of Child Health and Human Development of the National Institutes of Health — a distinction held by only a handful of neurodevelopmental centers nationwide committed to the diagnosis, prevention, treatment and amelioration of developmental disorders such as autism, fragile X syndrome and Down syndrome.
March 10, 2014
The hunt is on to find biomarkers that detect cancer, but it’s a challenging process. Early successes often are followed by heartbreaking failures.
March 7, 2014
Biomarkers for bone formation and resorption predict outcomes for men with castration-resistant prostate cancer, a team of researchers from UC Davis and their collaborators have found.
March 5, 2014
Atypical development can be detected as early as 12 months of age among the siblings of children with autism spectrum disorder, a study published by researchers with the UC Davis MIND Institute and UCLA has found.
February 28, 2014
Sacramento-area youth in the early stages of serious mental illness can receive a new smartphone app that helps them detect early warning signs of psychosis, through a one-year, $588,000 grant to the UC Davis Early Diagnosis and Preventive Treatment (EDAPT) Clinic from the Robert Wood Johnson Foundation, to study whether harnessing mobile technology improves patient care.
February 18, 2014
Justin Siegel, a biochemist at the University of California, Davis, who uses computers to develop new "designer enzymes" with properties not found in nature, has been awarded a prestigious Sloan Research Fellowship to support his work.
February 14, 2014
When mothers feed their newborns formula in the hospital, they are less likely to fully breastfeed their babies in the second month of life and more likely to quit breastfeeding early, even if they had hoped to breastfeed longer, UC Davis researchers have found. [en español or 中文 Chinese]
February 6, 2014
Helen Wu, a research and policy scientist in the UC Davis Institute for Population Health Improvement (IPHI), has been selected to receive a Robert Wood Johnson Foundation Mentored Research Scientist Development Award under its Public Health Services and Systems Research Program.
February 2, 2014
Governments could slow — and even reverse — the growing epidemic of obesity by taking measures to counter fast food consumption, according to a study published today in the Bulletin of the World Health Organization.