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January 2018arrow

UC Davis researcher urges caution on engineered stem cells

January 3, 2018

In a commentary published today in the New England Journal of Medicine, UC Davis researcher William Murphy expressed cautious optimism about efforts to genetically engineer hematopoietic stem cells (HSCs) to temporarily resist cell death during transplantation. While these gene therapy approaches could dramatically improve patient outcomes, Murphy argues that their risks must be carefully studied in diverse animal models.

December 2017arrow

Ophthalmologists increasingly dissatisfied with electronic health records

December 28, 2017

Ophthalmologists’ use of electronic health records (EHR) systems for storing and accessing patients’ medical histories more than doubled between 2006 and 2016, while their perceptions of financial and clinical productivity following EHR implementation declined, a study published today in JAMA Ophthalmology shows.

New grant funds study of immune cell activity in stem cell transplantation

December 21, 2017

A team of UC Davis investigators has been awarded a $1.2 million grant to examine a common virus and its effects on immune system function after stem cell transplantation.

Enhanced natural killer cells attack solid tumors

December 19, 2017

Human and veterinary researchers at UC Davis and other institutions have shown that enhanced natural killer (NK) immune cells, combined with radiation therapy, can be effective against spontaneous osteosarcoma (bone cancer) in dogs. The research showed these NK cells homed in on cancer and reduced metastasis in the treated dogs, offering a potential immunotherapy against solid tumors. The study was published today in the Journal for Immunotherapy of Cancer

Impact of medical marijuana laws on teen substance use differs by grade

December 14, 2017

A study assessing the impact of medical marijuana laws (MML) on adolescent substance use  has found decreased use of all substances among 8th graders, no change among 10th graders and increased non-medical use of prescription opioids and cigarette use among 12th graders, following MML enactment.

More new moms need recommended postpartum care

December 14, 2017

About half of new moms in California, including those with diabetes, do not receive critical follow-up care within three months after giving birth, a new study published in the December issue of the journal Contraception shows.

Microscope that uses ultraviolet instead of visible light emerging as powerful diagnostic tool

December 4, 2017

A microscope using ultraviolet light to illuminate samples enables pathologists to assess high-resolution images of biopsies and other fresh tissue samples for disease within minutes, without requiring the time-consuming preparation of conventional slides or destroying the tissue.

November 2017arrow

Statewide survey finds physicians, pharmacists comply with prescription drug monitoring registration. Next step: increase use

November 29, 2017

A state law that funded upgrades to California’s prescription drug monitoring program and mandated physicians, pharmacists and controlled substance prescribers to register by July 2016 significantly increased registration rates, a new survey of 1,904 California physicians and pharmacists conducted by the UC Davis Violence Prevention Program has found.

Denying patient requests lowers physician ratings

November 27, 2017

Patients who ask for specialist referrals, laboratory tests or certain medications and don’t get them tend to be less satisfied with their doctors than those whose requests are fulfilled, new research from UC Davis Health shows. Based on the results, the study authors recommend communications training for physicians that fosters positive experiences for patients without agreeing to all requests for particular diagnostics or treatments.

Study shows long-term benefits of steroid hormone medications in Duchenne muscular dystrophy

November 27, 2017

A large, multi-center, international study to assess the long-term benefits of glucocorticoid treatment for Duchenne muscular dystrophy (DMD) concludes that it does preserve muscle strength and function as well as reduce the risk of death for patients.

UC study finds performance on med school interviews linked to demographics

November 21, 2017

The medical school interview – a key determinant in the admissions process and, ultimately, in the physician workforce – appears to skew for or against applicants depending on their age, gender and self-identified disadvantaged socioeconomic status.

Maternal immune response affects genes in microglia, neural development

November 20, 2017

UC Davis MIND Institute esearchers have shown in a mouse model that an elevated maternal immune response changes the epigenetic landscape in offspring’s microglia, immune cells found in the brain and spinal cord. These changes affect genes associated with immune signaling and neural development, some of which have been implicated in autism spectrum disorder (ASD). The study was published online in the journal Glia.

In cancer, talking about bad news can be good

November 17, 2017

Giving bad news is never easy, especially when it’s life or death. But when an oncologist delivers a poor prognosis to a cancer patient, does it harm their relationship?  Some research studies have suggested it can.

Unlocking the genetics of cancer

November 7, 2017

For many, breast cancer is more than just a disease – it’s personal. One in eight women will be diagnosed with breast cancer at some point in their lives. But through new discoveries at the genetic level, the personal nature of cancer will eventually be what helps to beat it.