Dr. Muizelaar, a nationally recognized expert in cerebro vascular surgery, head injury and trauma, is at the forefront of new treatments for stroke and head injury. He has been instrumental in equipping the ICU with some of the most advanced computerized-monitoring equipment available. Dr. Muizelaar's research includes clinical trials of presynaptic calcium-channel blockers for patients with severe head injuries and the use of hypothermia in the treatment of these conditions. He also is investigating new treatments for patients with cerebral aneurysms.
Dr. Muizelaar's clinical subspecialty expertise includes cerebral aneurysms, cerebral arterio-venous malformations, carotid endarterectomy, severe trauma, intensive care, cerebral blood flow and metabolism, facial pain, specific pain syndrome, spinal stenosis, and degenerative disease. His surgical expertise includes complex aneurysms and arteriovenous malformations, carotid and vertebral constructive surgery, skull-base tumors, hearing preservation in acoustic tumors, medulla oblongata and spinal DREZ lesions, peripheral nerve surgery including brachial plexus surgery, and spinal interbody fusion techniques. Dr. Muizelaar's research interests focus on the design, implementation and conduct of clinical trials in severe head injury and subarachnoid hemorrhage; monitoring cerebral blood flow, cerebral blood volume and metabolism with various techniques in patients; and metabolism and basic mechanisms and pharmacotherapy in experimental brain injury.
4860 Y St., Suite 0100
Sacramento, CA 95817
Amsterdam, The Netherlands
University of Amsterdam School of Medicine
Amsterdam, The Netherlands
Congress of Neurological Surgeons
National Neurotrauma Society
Netherlands Society of Neurosurgeons
Neurosurgical Society of the Virginias
Richmond Academy of Medicine
Society of Neurological Surgeons ("Senior Society")
Stroke Council, American Heart Association
The International Neurotrauma Society
Select Recent Publications:
van Essen TA, Heeringa JJ and JP Muizelaar: (In) appropriate neurosurgical consultation. Clinical Neurology and Neurosurgery. 2010 Nov;112(9):775-80. Epub 2010 Jul 7.
Vergouwen MDI, Vermeulen M, Gijn J, Rinkel GJE, Widicks EF, Muizelaar JP, Mendelow AD, Juvela S, Yonas H, Terbrugge KG et al. Definiition of delayed cerebral ischemia after aneurismal subarachnoid hemorrhage as an outcome event in clinical trials and observational studies – Proposal of a multidisciplinary research group Stroke 2010 Oct;41(10):2391-5. Epub 2010 Aug 26.
Utter GH, Shahlaie K, Zwienenberg-Lee M and JP Muizelaar: Anemia in the setting of traumatic brain injury: The arguments for and against liberal transfusion. J. Neurotrauma 2011 Jan;28(1):155-65. Epub 2010 Dec 2.
Shahlaie K, Lyeth BG, Gurkorr GG, Muizelaar JP and RF Berman: Neuroprotective effects of selective N-type VGCC blockage on stretch-injury induced calcium dynamics in cortical neurons. Journal of Neurotrauma 27(1):175-187.
Fedor M, Muizelaar JP, Berman RF and BG Lyeth: Hippocampal theta dysfunction after lateral fluid percussion injury. Journal of Neurotrauma 27:1605-1615.
Keachie K, Muizelaar JP and K Shahlaie: Anterior thoracic arthorplasty: Indications and Technique. Journal of Neurosurgery: Spine 13(2):240-245.
Shahlaie K, Boggan JE, Latchaw RE, Ji C and JP Muizelaar: Practical Pearl.Posttraumatic vasospasm detected by continuous brain tissue oxygen monitoring: Treatment with intraarterial Verapamil and balloon angioplasty. Neurocritical Care 10:61-69.
Pennings FA, Kees W, Albrecht J, Muizelaar JP, Schuurman PR, and GJ Bouma: Abnormal responses of the human cerebral microcirculation to Papaverin during aneurysm surgery. Stroke 40:317-320.
Bavisetty S, McArthur DL, Dusick JR, Wang C, Cohan P, Boscardin WJ, Swerdloff R, Levin H, Chang DJ, Muizelaar JP and DF Kelly: Chronic Hypopituitarism after traumatic brain injury: risk assessment and relationship to outcome. Neurosurgery 62(5):1080-1093.
Narayan RK, Maas AI, Servadei F, Skolnick BE, Tillinger MN, Marshall LF, and the Traumatic Intracerebral Hemorrhage Study Group (includes JP Muizelaar): Progression of traumatic intracerebral hemorrhage: A prospective observational study. Journal of Neurotrauma, 25:629-639.