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UC Davis Health System

Mark J. Mannis, M.D. View profile as PDF

Mark J. Mannis

Clinical Interests

Dr. Mannis, Professor and Chair of the UC Davis Health System Eye Center, specializes in corneal transplantation and external diseases of the eye. His research has included development of experimental antimicrobial agents and growth factors that affect the corneal wound healing rate, skin diseases that affect the eye, and outcomes of corneal transplants and artificial corneas. Dr. Mannis has authored over 125 publications and five books on topics relating to corneal surgery and disease.


Chair of Ophthalmology




Ophthalmology and Vision Science


Cornea and External Disease, Refractive Surgery and Uveitis

Center/Program Affiliation:


Lawrence J. Ellison Ambulatory Care Center
Ophthalmology Clinic-Eye Center
4860 Y St., Suite 2400
Sacramento, CA 95817
Driving Directions
Phone: 916-734-6602

Laser Vision Correction Services - Department of Ophthalmology and Vision Science
Ophthalmology Clinic
77 Cadillac Dr.
Sacramento, CA 95825
Driving Directions
Phone: 916-734-6650

Additional Phone:

Physician Referrals: 800-4-UCDAVIS (800-482-3284)

Other Languages:

German, Hebrew, Portuguese, Spanish


M.D., University of Florida College of Medicine, Gainesville, Florida, 1975
B.A., Brandeis University, Waltham, Massachusetts, 1968


University of Vermont, Burlington, Vermont


Washington University, St. Louis, Missouri


University of Iowa, Iowa City, Iowa

Board Certifications:

American Board of Ophthalmology, 1980

Professional Memberships:

American Academy of Ophthalmology
American Association of Tissue Banks
American College of Surgeons
American Medical Association
American Ophthalmological Society
Association for Research in Vision and Ophthalmology
Association of American Medical Colleges
Association of University Professors of Ophthalmology
California Association of Ophthalmology
California Medical Association

Select Recent Publications:

Bradley JC, Graue-Hernandez EO, Schwab IR, Mannis MJ. Boston Type 1 Keratoprosthesis: The University of California Davis Experience. Cornea; April;28(3)321-7. 2009

Huang C, O'Hara M, Mannis MJ. Primary Pediatric Keratoplasty: Indications and Outcomes. Cornea; October;28(9) 1003-1008. 2009

Mannis MJ, Cornea Donor Study Investigator Group. The Effect of Donor Age on Corneal Transplantation Outcome: Results of the Cornea Donor Study. Ophthalmology; April; 115(4):620-626. 2008

Mannis MJ, Holland EJ, Beck RW, Belin MW, Goldberg MA, Gal RL, Kalajian AD, Kenyon KR, Kollman C, Ruedy KJ, Smith P, Sugar J, Stark WJ; Cornea Donor Study Group. Clinical profile and early surgical complications in the Cornea Donor Study. Cornea, 25(2):164-170. 2006

Feiz V, Moshirfar M, Mannis MJ, Reilly CD, Garcia-Ferrer F, Caspar JJ, Lim Me. Nomogram-based intraocular lens power adjustment after myopic photorefractive keratectomy and LASIK:anew approach. Ophthalmology, 112(8):1381-7. 2005

An HJ, Ninonuevo M, Aguilan J, Liu H, Lebrilla CB, Alvarenga LS, Mannis, MJ: Glycomics analyses of tear fluid for the diagnostic detection of ocular rosacea. J Proteome Res, 4(6): 1981-7. 2005

To see if Mark J. Mannis is accepting new patients, or for assistance finding a UC Davis doctor, please call 800-2-UCDAVIS (800-282-3284).