M.S., Southeast University Medical College, Nanjing, Jiangsu Province, 1986
Ph.D., University of Umea Faculty of Medicine, Umea, 1994
Thomas Jefferson University, Jefferson Medical College, Philadelphia, Pennsylvania, 1995-1999
American Society of Gene Therapy (ASGT)
International Society of Stem Cell Research (ISRCR)
Select Honors and Awards:
Innovative Development Award by the Academic Federation, UC Davis, 2006
Exploratory Research Award (R21) by the National Institute of Diabetes, Digestive and Kidney Diseases (NIDDK), 2005
Research Award from the American Cancer Society, 2003
Liver Scholar Award by the American Liver Foundation, 2000
National Service Research Award (NSRA) from the National Institutes of Health, the National Institute of Diabetes, Digestive and Kidney Diseases (NIDDK), 1997
Select Recent Publications:
2009 Kim JW, Wu J. RNAi, a powerful research tool and potential molecular therapy for liver diseases. In Yamada K & Hayashi S Eds: Small Interfering RNA: New Research. ISBN: 978-1-60692-158-6. Nova Science Publishers, Inc. Hauppauge, NY. 2009: in press.
2009 Nyunt T, Dicus CW, Yappert MC, Huser TR, Nantz MH, Wu J. Physico-chemical studies of poly(Cationic) lipid and polylipid nanoparticles for liver-based gene delivery. Bioconjugate Chemistry 2009; in press.
2009 Sangjeong Yoon, Tae-Hun Kim, Arutselvan Natarajan, Si-Si Wang, Moonseok Choi, Jian Wu, Mark A Zern, Senthil K Venugopal. Acute liver injury up-regulates microRNA-491_5p in mice, and its over-expression sensitizes Hep G2 cells for TNF-a-induced apoptosis. Liver International 2009; in press.
2009 Senthil K Venugopal, Joy Jiang, Tae-Hun Kim, Yong Li, Si-si Wang, Natalie J Torok, Jian Wu, Mark A Zern. Liver fibrosis causes down-regulation of miRNA-150 and miRNA-194 in hepatic stellate cells and their over-expression causes decreased stellate cell activation. Am J Physiol 2009; in press.
2009 Tatsukawa H, Fukaya Y, Frampton F, Martinez-Fuentes A, Suzuki K, Kuo K-F, Nagatsuma K, Shimokado K, Okuno M, Wu J, Iismaa S, Matsuura T, Tsukamoto H, Zern MA, Graham R, Kojima S. Role of trans glutaminase 2 in liver injury via crosslinking and silencing of transcription gactor, Spl. Gastroenterology 2009; 136:1783-95.
2009 Wu J, Hecker JH, Chiamvimonvat N. Antioxidant gene transfer for ischemic diseases. Advanced Drug Delivery Reviews. 2009; 61: 351-363.
Jian Wu, Jinsheng Guo. Autoimmune Hepatitis – Treatment Progresses. In Baoen Wang, Dingfeng Zhang et al. Edit: Contemporary Hepatology, 2nd Edition. Beijing: Science Press, Chinese Academy of Science, 2009: in press (senior author).
Kim JW, Wu J. RNAi, a powerful research tool and potential molecular therapy for liver diseases. In Yamada K & Hayashi S Eds: Small Interfering RNA: New Research. ISBN: 978-1-60692-158-6. Nova Science Publishers, Inc. Hauppauge, NY. 2009: in press.
2008 Choi MS, Catana AM, Wu J, Borowsky AD, Gambhir SS, Gupta S, Zem MA. Use of bioluminescent imaging to assay the transplantation of immortalized human fetal hepatocytes into mice. Cell Transplant 2008; 17:899-909.
2008 Ma XC, Duan YY, Catana AM, Jung C, Wu J, VandeVoort C, Zem MA. Differentiation of rhesus monkey embryonic stem cells along hepatocyte lineage. Cloning & Stem Cells 2008; 10(4):485-94.
2008 Pingguo Liu, Songqing He, Yanhong Zhang, Jian Wu. Protective Effects of Apocynin and Allopurinol on IschemialReperfusion-Induced Liver Injury in Mice. World Journal of Gastroenterology 2008; 14(18): 2832-2837 (senior author).