Joerg Lehmann, Ph.D.

Clinical/Research Interests

Dr. Lehmann is an Associate Adjunct Professor with a strong interest in clinical research, quality control, and implementation of new clinical technology. He has worked in the area of image-guided radiation therapy (IGRT) and started the department's image registry protocol. He also contributed to the work of the Advanced Technology Consortium (ATC), which facilitates the conduct of NCI-sponsored advanced technology radiation therapy clinical trials that require digital data submissions while maintaining patient confidentiality (atc.wustl.edu). Dr. Lehmann has also worked on nanoparticle-enabled hyperthermia, specifically on combined nanoparticle thermotherapy and radiation therapy in cells and in a nude mouse model. One of Dr. Lehmann's strong interests is Monte Carlo simulations of radiation transport. Using Monte Carlo simulations and measurements, Dr. Lehmann is working with other UCD faculty on an industry-sponsored project investigating the impact of radiation treatment on mandibles containing metal plates. Dr. Lehmann has been involved in dosimetry for in vivo studies on the effect of low doses of ionizing radiation on humans for several years. This includes Monte Carlo simulations of radiation dose to areas outside the treatment fields and measurements in this low-dose region. Dr. Lehmann is currently engaged as a Senior Medical Physicist with the Australian Clinical Dosimetry Service in Melbourne, Australia.

Title:

Associate Adjuct Professor

Specialty:

Cancer, Radiation Oncology

Center/Program Affiliation:

UC Davis Comprehensive Cancer Center

Other Languages:

German

Education:

Technical University of Ilmenau
Ilmenau,
Ph.D. 1999

Technical University of Ilmenau
Ilmenau,
M.S. 1995

Technical University of Ilmenau
Ilmenau,
B.S. 1991

Fellowships:

Stanford University
Stanford, California
2000
Radiation Oncology

Board Certifications:

American Board of Radiology, Therapeutic Radiological Physics, 2002
German Board Certification in Therapeutic Radiological Physics, 1998

Professional Memberships:

American Association of Physicists in Medicine (AAPM)
Association of German Engineers (VDI)
European Society for Therapeutic Radiology and Oncology (ESTRO)
German Society for Medical Physics (DGMP)
Society of Nuclear Medicine (SNM)

Honors and Awards:

Fulbright Grant, Medical Physics (Radiological Sciences), 1994

Select Recent Publications:

Berglund SR, Rocke DM, Dai J, Schwietert CW, Santana A, Stern RL, Lehmann J, Hartmann Siantar CL, Goldberg Z. Transient genome-wide transcriptional response to low-dose ionizing radiation in vivo in humans. Int J Radiat Oncol Biol Phys. 2008 Jan 1;70(1):229-34. Epub 2007 Nov 8.

Perks JR, Lehmann J, Chen AM, Yang CC, Stern RL, Purdy JA. Comparison of peripheral dose from image-guided radiation therapy (IGRT) using kV cone beam CT to intensity-modulated radiation therapy (IMRT). Radiother Oncol. 2008 Dec;89(3):304-10. Epub 2008 Aug 31.

Narayan S, Lehmann J, Coleman MA, Vaughan A, Yang CC, Enepekides D, Farwell G, Purdy JA, Laredo G, Nolan K, Pearson FS, Vijayakumar S. Prospective evaluation to establish a dose response for clinical oral mucositis in patients undergoing head-and-neck conformal radiotherapy. Int J Radiat Oncol Biol Phys. 2008 Nov 1;72(3):756-62. Epub 2008 Apr 15.

Lehmann J, Natarajan A, Denardo GL, Ivkov R, Foreman AR, Catapano C, Mirick G, Quang T, Gruettner C, Denardo SJ. Short communication: nanoparticle thermotherapy and external beam radiation therapy for human prostate cancer cells. Cancer Biother Radiopharm. 2008 Apr;23(2):265-71.

Lehmann J, Perks J, Semon S, Harse R, Purdy JA. Commissioning experience with cone-beam computed tomography for image-guided radiation therapy. J Appl Clin Med Phys. 2007 Jul 17;8(3):2354.

DeNardo GL, Hok S, Van Natarajan A, Cosman M, DeNardo SJ, Lightstone FC, Mirick GR, Yuan A, Perkins J, Sysko VV, Lehmann J, Balhorn RL. Characteristics of dimeric (bis) bidentate selective high affinity ligands as HLA-DR10 beta antibody mimics targeting non-Hodgkin's lymphoma. Int J Oncol. 2007 Oct;31(4):729-40.

Berglund SR, Schwietert CW, Jones A, Stern RL, Lehmann J, Goldberg Z. Optimized methodology for sequential extraction of RNA and protein from small human skin biopsies. Journal of Investigative Dermatology. (In press)

Lehmann J, DeNardo GL, Yuan A, Shen S, O’Donnell RT, Richman C, DeNardo SJ. Comparison of normal tissue pharmacokinetics with 111In/90Y monoclonal antibody m170 for breast and prostate cancer. Int J Radiat Oncol Biol Phys. (In press)