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Department of Internal Medicine

C. Tissa Kappagoda, M.D., Ph.D. View profile as PDF

C. Tissa  Kappagoda

Clinical Interests

C. Tissa Kappagoda specializes in regression of atherosclerosis and methods for restoring endothelium-derived relaxing factor. He is interested in treatment of coronary atherosclerosis, obesity and type 2 diabetes by lifestyle modifications such as exercise training, low-fat diet and stress management. His research focuses on heart failure, endothelial findings and clinical trials of nutritional supplements.


Director of Cardiac Rehabilitation Program
Director of the Coronary Heart Disease Reversal Program


Cardiology, Cardiovascular Medicine, Internal Medicine


Internal Medicine


Cardiovascular Medicine

Center/Program Affiliation:


Lawrence J. Ellison Ambulatory Care Center
Cardiology Clinic
4860 Y St., Suite 0200
Sacramento, CA 95817
Driving Directions
Phone: 800-282-3284

Additional Phone:

Physician Referrals: 916-734-5678


M.D., University of Ceylon, Ceylon, 1965


Royal College of Physicians, London, 1983-88

Professional Memberships:

American Academy of Otolaryngology-Head and Neck Surgery
American College of Cardiology
Fellow of the American Heart Association
Fellow of the Royal College of Physicians of Canada
Fellow of the Royal College of Physicians of Edinburgh
Fellow of the Royal College of Physicians of London

Select Recent Publications:

Edirisinghe I, Banaszewski K, Cappozzo J, Sandhya K, Ellis CL, Tadapaneni R, Kappagoda CT, Burton-Freeman BM. Strawberry anthocyanin and its association with postprandial inflammation and insulin. Br J Nutr. 2011;1-10.

Kappagoda CT, AMerstadam EA,. Assessment of risk for developing coronary heart disease in asymptomatic individuals. J Cardiopulm Rehavil Prev. 2009; 29(4): 207-219.

Kappagoda CT, Amsterdam EA. Another look at the results of the JUPITER trial.American Journal of Cardiology 2009;104(11):1603-5.

Karalliedde LD, Kappagoda CT. The Challenge of traditional Chinese medicines for allopathic practitioners. Am J Physiol Heart Circ Physiol. 2009;297(6):H1967-H1969.

Amsterdam EA, Kappagoda CT. Current approaches to the challenge of coronary heart disease risk assessment: C-reactive protein mania and imaging-itis? Prev Cardiol. 2009;12(1):1-2.

CT Kappagoda, Hyson, DA and Amsterdam EA High Protein Low Carbohydrate Diets - Have they a place in clinical cardiology JACC Volume 43, 725-730, 2004.

A.A. Ma, Bravo, M and Kappagoda, C.T. Responses of bronchial C-fiber afferents of the rabbit to changes in lung compliance. Respiratory Physiology and Neurobiology Respir Physiol Neurobiol. 2003 Nov 14;138(2-3):155-63.

Gunawardena, S., Ravi, K., Longhurst, J.C., Kaufman, M.P. CT Kappagoda. Responses of C fibre afferents of the rabbit airways and lungs to changes in extra-vascular fluid volume. Respiratory Physiology and Neurobiology 132: 239-251, 2002.

Parks, EJ, Rutlege, JC, Davis, PA, Hyson, DA, Schneeman, BO, CT Kappagoda. Predictors of plasma triglyceride elevation in patients participating in a coronary atherosclerosis treatment program. J Cardiopulm Rehabil 2001 Mar-Apr;21(2):73-9.

Symons, JD, Gunawardena, S, CT Kappagota, Dhond, MR. Volume overload left ventricular hypertrophy: effects on coronary microvascular reactivity in rabbits. Exp Physiol. 86(6):725_32, 2001.

Karim, M, K McCormick, CT Kappagoda. Effects of Cocoa Extracts on Endothelium Dependent Relaxation. Journal of Nutrition. Aug;130(8S Suppl):2105S-8S, 2000.

CT Kappagoda, Karim, M, McCormick, K. Flavonoids in Grape Seeds - Unraveling the French Paradox. Chemical Innovation 30 (9): 27-31, 2000.

CT Kappagoda. Endothelial nitric oxide synthase and estrogen. Cardiovascular Research 47(1): 9-10, 2000.

CT Kappagoda, Cort, D, Myers, S, Perry, E. Clinical Evaluation of Stress: An Opinion. Preventative Cardiology 3 (4): 152-153, 1999.

Kappagoda, CT; and E Amsterdam. How much to lower serum cholesterol: is it the wrong question? Journal of the American College of Cardiology 34(1): 289-292, 1999.

Gunawardena, S, E Bravo, CT Kappagoda. Rapidly adapting receptors in a rabbit model of mitral regurgitation. Journal of Physiology 521(3): 739-748, 1999.

To see if C. Tissa Kappagoda is accepting new patients, or for assistance finding a UC Davis doctor, please call 800-2-UCDAVIS (800-282-3284).