Suzanne Miyamoto, Ph.D.

Clinical/Research Interests

Suzanne Miyamoto is a principal investigator in the Division of Hematology and Oncology whose research interests involve translational clinical research projects to identify relevant glycomic, proteomic and glycomic biomarkers of cancer to assist with diagnosis, early detection and monitoring of treatment for ovarian, breast, prostate and lung cancers. The basic research projects in her laboratory investigate how signaling pathways regulate translation initiation and the translatability of specific mRNAs in normal mammalian cells, and how this process is dysregulated in cancer cells.

Title:

Associate Research Biochemist

Specialty:

Hematology and Oncology, Cancer, Internal Medicine

Center/Program Affiliation:

UC Davis Comprehensive Cancer Center

Education:

New York Medical College
Valhalla, New York
Ph.D. 1990

New York Medical College
Valhalla,
M.S. 1982

UC Riverside
Riverside, California
B.A. 1971

Fellowships:

NHLBI NIH (National Research Council Research Associate Fellowship)
Bethesda, MD
1990-1993
Molecular Hematology Branch

Professional Memberships:

American Association for Cancer Research
American Association for the Advancement of Science
American Society of Biochemistry
American Society of Mass Spectrometry
American Society of Microbiology
Molecular Biology

Honors and Awards:

National Research Council Associate Fellowship, 2000

Select Recent Publications:

Kronewitter, S. R., An, H. J., de Leoz, M. L., Lebrilla, C. B., Miyamoto, S., Leiserowitz, G. S. The development of retrosynthetic glycan libraries to profile and classify the human serum N-linked glycome. Proteomics 9(11): 2986-2994. 2009

Chu, C.S., Niñonuevo, M.R., Clowers, B.H., Clowers, Perkins P., An, H.J., Hongfeng Yin, H., Killeen, K., Miyamoto, S., Grimm, R., and Lebrilla, C.B. Profile of Native N-linked Glycan Structures from Human Serum Using High Performance Liquid Chromatography on a Microfluidic Chip and Time-of-Flight Mass Spectrometry. Proteomics Apr;9(7):1939-51. 2009.

Barkauskas, D. A., An, H. J., Kronewitter, S. R., de Leoz, M. L., Chew, H. K., de Vere White, R. W., Leiserowitz, G. S., Miyamoto, S., Lebrilla, C. B. and Rocke, D. M. Detecting glycan cancer biomarkers in serum samples using MALDI FT-ICR mass spectrometry data. Bioinformatics. Jan 15;25(2):251-7. 2009

deLeoz, M.L., An, H.J., Kronewitter, S., Kim, J., Beecroft, S., Vinall, R., Miyamoto, S., deVere White, R., Lam, K.S., Lebrilla, C.B. Glycomic approach for potential biomarkers on prostate cancer: Profiling of N-linked glycans in human serum and pRNS cell lines. Dis Markers. 2008;25(4-5):243-58

Li, B. An, H.J., Kirmiz, C., Lebrilla, C.B. Lam, K.S., and Miyamoto, S. Glycoproteomic analyses of ovarian cancer cell lines and sera from ovarian cancer patients show distinct glycosylation changes in individual proteins. J. Proteome Research Sep;7(9):3776-88. 2008

Miyamoto, S., Liu, R., and Lam, K.S. Screening of a one-bead one compound combinatorial library for ?-actin identifies molecules active toward Ramos B-lymphoma B cells. Anal. Biochem. 374 122-120. 2008

Kirmiz, C., Li, B., An, H.J., Clowers, B., Ferrige, A., Alecio, R., Sulaimon, S., Lebrilla, C.B., and Miyamoto, S. A Serum Glycomics Approach to Breast Cancer Biomarkers. Molecular and Cellular Proteomics. Jan;6(1):43-55. 2007.

Leiserowitz, G.S., Lebrilla, C., Miyamoto, S., An, H.J., Duong, H., Kirmiz, C., Li, B., Liu, H., and Lam, K.S. Glycomics analysis of serum: a potential new biomarker for ovarian cancer? Int J Gynecol Cancer. 2007 Jul 26; [Epub ahead of print]

An, H.J., Miyamoto, S., Lancaster, K.S., Kirmiz, C., Li, B., Lam, K.S., Leiserowitz, G..S., and Lebrilla, C.B. Global Profiling of Glycans in Serum for the Diagnosis of Potential Biomarkers for Ovarian Cancer. J Proteome Res. Jul;5(7):1626-35. 2006

Miyamoto, S. Clinical applications of glycomic approaches for the detection of cancer and other diseases. Curr. Opin. Mol. Ther. 8(6): 507-13. 2006