My research is in the field of nanoscience and specifically in exploring the interactions between inorganic nanomaterials and biomolecules. By taking advantage of synthetic chemistry, bioconjugation and other biomolecular tools I am attempting to create new bionanomaterials with advanced properties.
My goal is to develop new synthetic strategies for creating multi-functional nanoparticles and to gain a better understanding on how nanomaterials interact with biomolecules. The methods and knowledge acquired through this research will possibly lead to next-generation diagnostic tools and therapeutic approaches for cancer and other diseases.
B.S., University of Bologna, Bologna, 1995
Select Recent Publications:
Berti, L., D'Agostino, P.S., Boeneman, K., Medintz, LL. Improved Peptidyl Linkers for Self-Assembling Semiconductor Quantum Dot Bioconjugates, (2009), Nano Res. , 2, 121-129.
Berti, L., Medintz, LL., Alessandrini, A., Facci, P. A one-pot functionalization strategy for immobilization of proteins onto a linear DNA scaffold, (2009), Nanotechnology, 20, 235101.
Alessandrini, A., Berti, L., Gazzadi, G.C., Facci, P. Imparting chemical specificity to nanometer-spaced electrodes, (2008), Nanotechnology, 19, 355303.
Berti, L., Burley, G.A, Nucleic Acid and Nucleotide-Mediated Synthesis of Inorganic Nanoparticles, (2008), Nature Nanotech., 3, 81-87.
Berti, L., Alessandrini, A., Bellesia, M., Facci, P. Fine-Tuning Nanoparticle Size by Oligo(guanine)n Templated Synthesis of CdS: an AFM study, (2007), Langmuir, 23, 10891-10892.
Medintz, LL., Berti, L., Pons, T., Grimes, A.F., English, D.S., Alessandrini, A., Facci, P., Mattoussi, H. A Reactive Peptidic Linker for Self-Assembling Hybrid Quantum Dot-DNA Bioconjugates, (2007), Nano Lett. , 7, 1741-1748.
Berti, L., Alessandrini, A., Menozzi, C., Facci, P. Controlled DNATemplated Metal Deposition: Towards Ultra-Thin Nanowires (2006), J. Nanosci. Nanotech. , 6, 2382-2385.
Berti, L., Alessandrini, A., Facci, P., DNA-templated photoinduced silver deposition, (2005), J. Am. Chem. Soc., 127, 11216-11217.
Berti, L., Xie, J., Medintz, L.L, Glazer, A.N. and Mathies, R.A., Energy-Transfer Cassettes for Facile Labeling of Sequencing and peR Primers, (2001), Anal. Biochemistry, 292, 188-197.