Saul Schaefer, M.D.

Clinical/Research Interests

Saul Schaefer focuses his clinical research on the efficacy of contrast-enhanced cardiac MRI to define abnormal perfusion in patients with ischemic heart disease and MRI of coronary blood flow and anatomy with intravenous adenosine. Schaefer's laboratory studies involve regulation of myocardial metabolism and ion transport during low flow and total ischemia. He also is researching use of perfused heart models of ischemic preconditioning and hibernating myocardium, coupled with nuclear magnetic resonance spectroscopy (MRS) and biochemical assays, to define adaptive mechanisms to ischemia.

Title:

Professor, Chief of Cardiology at VA Medical Center in Sacramento

Specialty:

Cardiovascular Medicine, Cardiology, Internal Medicine

Center/Program Affiliation:

Cardiovascular Services

Address:

Lawrence J. Ellison Ambulatory Care Center
4860 Y St., Suite 200
Sacramento, CA 95817

Phone:

(916) 734-8321

Education:

UC Davis School of Medicine
Sacramento, California
M.D. 1981

The Cooper Union
New York City, New York
1968

Residency:

University of California, San Francisco
San Francisco, California
1981-84

Fellowships:

University of Texas Southwestern Medical Center
Dallas, Texas
1984-87

Board Certifications:

American Board of Internal Medicine, Cardiovascular Disease, 1987
American Board of Internal Medicine, 1984

Professional Memberships:

American College of Cardiology
American Federation of Clinical Research
American Heart Association
American Society of Echocardiography
Society of Magnetic Resonance in Medicine

Select Recent Publications:

Phillips W, Schaefer S. LDL= 5: Virtues and Dangers of Multidrug Therapy of Low-Density Lipoprotein Cholesterol. Journal of Preventative Cardiology, 2010;13: 71.

Lu X, Liu H, Wang, L, Schaefer S. Activation of NF-kB is a critical element in the anti-apoptotic effect of anesthetic preconditioning. American

Connolly SJ, Ezekowitz MD, Yusuf S, Eikelboom J, Oldgren J, Parekh A, Pogue J, Reilly PA, Themeles E, Varrone J, Wang S, Alings M, Xavier D, Zhu J, Diaz R, Lewis BS, Darius H, Diener HC, Joyner CD, Wallentin L; RE-LY Steering Committee and Investigators. [Saul Schaefer member of the Dabigatran Study Group]. Dabigatran versus warfarin in patients with atrial fibrillation. New England Journal of Medicine, 2009;361(12): 1139-51.

Konia M, Schaefer S, H Liu. Nuclear factor-kB inhibition provides additional protection against ischemia reperfusion injury in sevoflurane preconditioning. European Journal of Anesthesiology, 2009;26: 496-503.

Lopez JE, Yeo KK, Caputo G, Buonocore M, Schaefer S. Recovery of methamphetamine associated cardiomyopathy predicted by late gadolinium enhanced cardiovascular magnetic resonance. Journal of Cardiovascular Magnetic Resonance, 2009;11(1): 46. Publications and Contributions to Jointly Authored Works 7

Tamse C, Lu X, Mortel E, Cabrales E, Feng W, S Schaefer. The Peripheral Benzodiazepine Receptor Modulates Ca2 Transport through the VDAC in Rat Heart Mitochondria. Journal of Clinical and Basic Cardiology, 2008;11: 24-29.

Southard J, Baker L, S Schaefer. In Search of the False-Negative ETT -Evidence-Based Use of Exercise Echocardiography. Clinical Cardiology, 2007;30.

To see if Saul Schaefer is accepting new patients, or for assistance finding a UC Davis doctor, please call (800) 2-UC DAVIS.