Lawrence J. Laslett specializes in general cardiology, providing both short- and long-term cardiac care. His practice focuses on acute-care cardiac problems, (particularly coronary disease), including diagnostic catheterization, coronary angioplasty and stent placement. Laslett's research involves the effects of angiographic contrast on left ventricular function and dynamic resistance exercise on myocardial oxygen supply and demand. He is also assessing post-thrombosis coronary anatomy, potential myocardial injury from high-intensity endurance running, and the impact of serologic infarct markers on prognosis for "rule out" MI patients.
M.D., University of Iowa College of Medicine, Iowa City, Iowa, 1969
B.S., Iowa State University, Ames, Iowa, 1964
University of California, Davis Medical Center, Sacramento, California, 1976
University of California, Davis Medical Center, Sacramento, California, 1978
American Board of Internal Medicine, 1976
American Board of Internal Medicine, Cardiovascular Medicine, 1981
American College of Cardiology
American Heart Association
Honors and Awards
Service Award, California Chapter, American College of Cardiology, 2000
Kaiser Foundation Annual Award for Excellence in Clinical Science Teaching, 2000
Select Recent Publications
Hawkes WC, Laslett LJ. Selenium supplementation does not improve vascular responsiveness in healthy North American men. American Journal Physiology Heart Circulation Physiology 2009;296:H256-H262.
Hecker JG, Laslett L, Campbell E, Nunnally M, O'Connor A, Ellis JE, Frogel JK, Fleisher LA. Catastrophic Cardiovascular Collapse During Carotid Endarterectomy. Journal of Cardiothoracic and Vascular Anesthesia 2006;20:259-268.
Wang H, Laslett LJ, Richman CM, Wun T. Acute myocardial infarction in hemoglobin SC disease. Annals of Hematology 2004;83:622-624.
Laslett L. Did you know? Chelation therapy: New proof of lack of efficacy. Preventive Cardiology 2002;2:91-92.
Laslett L. Exercise electrocardiography in the asymptomatic patient. Chapter 8 in: Ellestad MH, Amsterdam EA, Exercise Testing. New Concepts for the New Century. Kluwer Academic Publishers, Boston, 2002
Amsterdam EA, Laslett L, Diercks D, Kirk JD. Reducing the knowledge-practice gap in the management of patients with cardiovascular disease. Preventive Cardiology 2002;1:12-15.
Schaefer S, SD Correa, L Laslett, RJ Valente. Blockade of adenosine receptors with aminophylline limits ischemic preconditioning in man. American Heart Journal 142:E4, 2001.
Laslett L, Eisenbud E. Lack of detection of myocardial injury during competitive races of 100 miles lasting 18 to 30 hours. American Journal of Cardiology 1997;80:379-380
Laslett L. Risk for exercise-induced myocardial injury for athletes performing prolonged strenuous endurance exercise - Reply. American Journal of Cardiology 1997;80:544
Laslett L, Eisenbud E, Lind R. Evidence of Myocardial 6; Injury During Prolonged Strenuous Exercise. American Journal of Cardiology 1996;78:488-490
Laslett L. Normal left coronary artery diameter can be predicted from diameters of its branch vessels Clinical Cardiology 1995;18:580-582
Schaefer A, R Valente, Laslett L, JC Longhurst. Cardiac reflex effects of intracoronary bradykinin in humans Journal of American Coll. Cardiology Invest. Medicine 1995;44:160-176