JoAnne Natale, M.D., Ph.D.

JoAnne E. Natale, M.D., Ph.D.


Pediatric Critical Care




  • Medical Director, UC Davis Children's Hospital Pediatric Intensive Care Unit
  • Professor
To see if JoAnne E. Natale is accepting new patients, or for assistance finding a UC Davis doctor, please call 800-2-UCDAVIS (800-282-3284).

UC Davis Children's Hospital

2315 Stockton Blvd.
Sacramento, CA 95817
Driving Directions

Primary Phone:

Additional Phone Numbers

Physician Referrals: 800-4-UCDAVIS (800-482-3284)

Clinical Interests

Dr. Natale has clinical interests in pediatric critical care medicine. Her research interests focus on quality improvement, neurocritical care and clinical trials in critically ill children.


Pediatric Critical Care

Center/Program Affiliation

UC Davis Children's Hospital


M.D., Michigan State University, East Lansing, Michigan, 1993

Ph.D., University of Michigan Medical School, Ann Arbor, Michigan, 1988

B.S., Allentown College, Center Valley, Pennsylvania, 1984


Albert Einstein/Montefiore Medical Center, Bronx, New York, 1996


Johns Hopkins Hospital, Baltimore, Maryland, 1999

Board Certifications

American Board of Pediatrics, 1996

American Board of Pediatrics, Critical Care Medicine, 2000

Professional Memberships

American Academy of Pediatrics, Fellow

National Neurotrauma Society

Neurocritical Care Society

Society for Pediatric Research, Elected member

Society of Critical Care Medicine

Western Society for Pediatric Research

Honors and Awards

Ambassador of Diversity, UC Davis Health System, 2008

Award for Scientific and Academic Achievement, Clinical Research by Junior Faculty, Children?s Research Institute, Children?s National Medical Center, 2005

Select Recent Publications

Natale J, Joseph J, Rogers A, Mahajan P, Cooper A, Wisner D, Miskin M, Hoyle J, Atabaki S, Dayan P, Holmes J, Kuppermann N. Cranial CT use for minor head trauma in children is associated with race/ethnicity. Arch Child Adolescent Med. 166(8):732-777.

Klein P, Herr D, Pearl PL, Natale J, Levine Z, Nogay C, Sandoval F, Trzcinsky S, Atabaki SM, Tsuchida T, van den Anker J, Soldin SJ, He J, McCarter R.  Results of phase 2 safety and feasibility study of treatment with levetiracetam for prevention of posttraumatic epilepsy: Archives of Neurology.  2012; 69(10):1290-1295.

Klein P, Herr D, Pearl PL, Natale J, Levine Z, Nogay C, Sandoval F, Trzcinsky S, Atabaki SM, Tsuchida T, van den Anker J, Soldin SJ, He J, McCarter R.  Results of phase 2 pharmacokinetic study of levetiracetam for prevention of post-traumatic epilepsy.  Epilepsy and Behavior. 2012; 24(4):457-61.

Shaikh, U, Natale J, Nettiksimmons J, Li ST. Improving pediatric healthcare delivery by engaging residents in team-based quality improvement projects. Amer J Med Quality.  2012; 28(2):120-126.

Natale JE, Joseph JG, Honomichl RD, Bazanni LG, Kagawa KJ, Marcin JP. Benchmarking, public reporting, and pay-for-performance: A mixed-methods survey of California pediatric intensive care unit medical directors. Pediatr Crit Care Med. 2011 Nov;12(6):e225-32.

Plymale J, Park J, Natale J, Moon-Grady A. Corrected QT Interval in Children With Brain Death. Pediatr Cardiol. 2010 Oct;31(7):1064-9. Epub 2010 Aug 20.

Natale JE, Hamburger E, Aman M, Asmerom W,Faisal A, Gebremichael F, Haile S, Maekele M, Mohammed M,Tesfaye D, Ghiorghis B, Joseph JG. Intervention to Reduce Parental Bypass of Community Pediatric Primary Health Facilities in Asmara, Eritrea. Journal of Primary Care Community Health 2010 Oct; 1(3): 213-217.

Salorio CF, Slomine BS, Guerguerian AM, Christensen JR, White JR, Natale JE,Shaffner DH, Grados MA, Vasa RA, Gerring JP. Intensive care unit variables and outcome after pediatric traumatic brain injury: a retrospective study of survivors. Pediatr Crit Care Med. 2008 Jan;9(1):47-53.

Natale JE*, Guerguerian A-M*, Joseph JG, McCarter R, Shao C, Slomine B, Christensen J, Johnston J, Shaffner DH. (*equal contributors). Randomized trial of magnesium sulfate infusion in children with severe traumatic brain injury: Feasibility and hemodynamic safety. Pediatric Critical Care Medicine, 8(1):1-9, 2007. (feature article)

Natale JE, Joseph JG, Pretzlaff R, Silber T, Guerguerian AM. Clinical trials in pediatric traumatic brain injury: Unique challenges and potential responses. Developmental Neurosci, 28:276-290, 2006.