Kuppermann's research has focused on the evaluation and treatment of infectious emergencies in children; laboratory and radiographic evaluation of pediatric trauma patients; and pediatric diabetic ketoacidosis and the risk of cerebral injury and cerebral edema. He has made important contributions on developing algorithms that can help doctors rapidly distinguish infants and children with viral from bacterial infections -- such as meningococcal infections and meningitis -- enabling appropriate treatments to be started more promptly for those who need them, and obviating antibiotics for those who do not.
Kuppermann is an elected member of the Institute of Medicine (IOM) and chairs the American Academy of Pediatrics (AAP) Pediatric Emergency Medicine Collaborative Research Committee. Kupperman holds the Bo Tomas Brofeldt Endowed Chair in the Department of Emergency Medicine at UC Davis.
San Francisco, California
Harvard University School of Public Health
Palo Alto, California
Pediatric Emergency Medicine
American College of Emergency Physicians
American Pediatric Society
Society for Academic Emergency Medicine
Western Society for Pediatric Research
Honors and Awards:
Excellence in Research Award, Society for Academic Emergency Medicine, 2010
National Heroes Award, U.S. Department of Health and Human Services, Emergency Medical Services for Children Program, 2010
Miller-Sarkin Mentoring Award, Academic Pediatric Association (APA), 2009
UC Davis Award for Outstanding Contributions to Faculty Development and Diversity, 2007
UC Davis School of Medicine Dean’s Award for Excellence in Research and Clinical Mentoring, 2003
Select Recent Publications:
Kuppermann N, Holmes J, Dayan P, et al, and the Pediatric Emergency Care Applied Research Network (PECARN). Identification of Children at Very Low Risk of Clinically-Important Brain Injuries: a Prospective Cohort Study. Lancet 2009;374:1160-70.
Papa L, Kuppermann N, Lamond K, et al. Structure and Function of Emergency Care Research Networks: Strengths, Weaknesses and Challenges. Acad Emerg Med 2009;16:995-1004.
Holmes JF, Wisner DH, McGahan JP, Mower WR, Kuppermann N. Clinical Prediction Rules for Identifying Adults at Very Low Risk of Intra-abdominal Injuries after Blunt Trauma. Ann Emerg Med 2009;54:575-84.
Holmes JF, Mao A, Awasthi S, McGahan J, Wisner D, Kuppermann N. Validation of a Prediction Rule for the Identification of Children with Intra-abdominal Injuries after Blunt Torso Trauma. Ann Emerg Med 2009;54:528-33.
Kanagaye J, Nigrovic L., Malley R, et al, and Kuppermann N for the Pediatric Emergency Medicine Collaborative Research Committee of the AAP. Diagnostic Value of Immature Neutrophils (Bands) in the Cerebrospinal Fluid of Children with CSF Pleocytosis. Pediatrics 2009;123:e967-71.
Krief W, Levine D, Platt S, Macias C, Dayan P, Zorc J, Feffermann N and Kuppermann N. Influenza Virus Infection and the Risk of Serious Bacterial Infections in Young Febrile Infants. Pediatrics 2009;124:30-9.
Nigrovic L, Malley R, Kuppermann N. CSF Pleocytosis in Children in the Era of Bacterial Conjugate Vaccines: Distinguishing the Child with Bacterial and Aseptic meningitis. Pediatr Emerg Care 2009;25:112-7.
Palchak M, Holmes J, Kuppermann N. Clinical Judgment versus a Decision Rule for Identifying Children at Very Low Risk for Traumatic Brain Injury after Blunt Head Trauma. Pediatr Emerg Care 2009;25:61-5.
Holmes JF, Kuppermann N and PECARN. Guardian Availability for Children Evaluated in the Emergency Department for Blunt Head Trauma. Acad Emerg Med 2009;16:15-20.