Ralph de Vere White Professor and Director of Urologic Research
Co-Leader, Prostate Cancer Program
Ph.D., University of Texas, Houston, School of Public Health, Houston, Texas, 1995
Ad Hoc member for NIH Metabolic Study Section
Ad Hoc reviewer for NIH Tumor Microenvironment study section
Editorial Board, The Prostate
Member, ACS TBE study section
NCI Special Emphasis Panel, Cancer Prognosis and Prediction
Reviewer Committee Member, O’Brien Urology Center Program
Scientific Reviewer Panel, DOD Prostate Cancer Program, Breast Cancer Program
Select Honors and Awards:
Ralph deVere White Endowed Professor of Urologic Research, University of California, Davis, 2008
First prize award, AUA Assay Contest, Gleave, M., Hsieh JT, Gao A.C. Von Eschenbach A.C., and Chung L.W.K. Acceleration of Human Prostate Cancer Growth in vivo by Factors Produced by Prostate and Bone Fibroblasts., 1991
Select Recent Publications:
Zhu YZ, Liu, C.F., Nadiminty, N., Lou, W., Tummala, R., Evans, C.P., Gao, A. C. Inhibition of ABCB1 expression overcomes acquired docetaxel resistance in prostate cancer. Mol Cancer Ther 2013 12 (9): 1829-36.
Nadiminty N, Tummala R, Lou W, Zhu YZ, Evans CP, Gao AC. NF-kB2/p52 induces resistance to enzalutamide in prostate cancer: role of androgen receptor and its variants. Molecular Cancer Ther 2013 12 (8): 1629-37.
Tummala R, Nadiminty N, Lou W, Zhu YZ, Chen HW, Evans CP, Gao AC. Lin28 promotes growth of prostate cancer cells and activates the androgen receptor. American J. of Pathology. 2013 183 (1): 288-95.
Nadiminty N, Tummala R, Lou W, Zhu Y, Zhang J, Chen X, eVere White RW, Kung HJ, Evans CP, Gao AC. MicroRNA let-7c suppresses androgen receptor expression and activity via regulation of Myc expression in prostate cancer cells. J Biol Chem. 2012 Jan 6;287(2):1527-37. Epub 2011 Nov 28.
Liu C, Nadiminty N, Tummala R, Chun JY, Lou W, Zhu Y, Sun M, Evans CP, Zhou Q, Gao AC. Andrographolide targets androgen receptor pathway in castration-resistant prostate cancer. Genes Cancer. 2011 Feb;2(2):151-9.
Nadiminty N, Lou W, Sun M, Chen J, Yue J, Kung HJ, Evans CP, Zhou Q, Gao AC. Aberrant activation of the androgen receptor by NF-kappaB2/p52 in prostate cancer cells. Cancer Res. 2010 Apr 15;70(8):3309-19. Epub 2010 Apr 13.
Feng S, Tang Q, Sun M, Chun JY, Evans CP, Gao AC. Interleukin-6 increases prostate cancer cells resistance to bicalutamide via TIF2. Mol Cancer Ther. 2009 Mar;8(3):665-71. Epub 2009 Feb 24.
Chun JY, Nadiminty N, Dutt S, Lou W, Yang JC, Kung HJ, Evans CP, Gao AC. Interleukin-6 regulates androgen synthesis in prostate cancer cells. Clin Cancer Res. 2009 Aug 1;15(15):4815-22. Epub 2009 Jul 28.
Nadiminty N, Chun JY, Lou W, Lin X, Gao AC. NF-kappaB2/p52 enhances androgen-independent growth of human LNCaP cells via protection from apoptotic cell death and cell cycle arrest induced by androgen-deprivation. Prostate. 2008 Dec 1;68(16):1725-33.
Chun JY, Hu Y, Pinder E, Wu J, Li F, Gao AC. Selenium inhibition of survivin expression by preventing Sp1 binding to its promoter. Mol Cancer Ther. 2007 Sep;6(9):2572-80.
Nadiminty N, Lou W, Lee SO, Lin X, Trump DL, and Gao AC. Stat3 activation of NF-kB p100 processing involves CBP/p300 mediated acetylation. Proc Natl Acad Sci USA, 103 (19): 7264-7269, 2006