Anatomic pathology: research
Faculty within the Division of Anatomic Pathology are involved in a variety of collaborative research with multi-disciplinary teams. These include faculty members from many different departments and centers within our School of Medicine, the general UC Davis campus, and at other institutions.
Faculty list with research and clinical interests
Alaa Afify, M.D. : serous effusions, mesothelioma
Alexander Borowsky, M.D.: breast pathology
William Ellis, M.D.: neuropathology
Regina Gandour-Edwards, M.D.: genitourinary and prostate pathology
Claudia Greco, M.D.: neuropathology
Lydia Howell, M.D.: breast and cervical cytology and pathology, quality assurance and error reduction
Thomas Konia, M.D.: pulmonary pathology, dermatopathology
Renuka Lakshminarayanan, M.D.: soft tissue and bone pathology
Hemlata Oswal, M.D.: gynecologic and breast pathology
Rajen Ramsamooj, M.D.: transplant pathology, breast pathology
Ramez Saroufeem, M.D.: gastrointestinal and liver pathology, autopsy pathology
Research support services in anatomic pathology
Anatomic Pathology supports the research mission through the following resources:
Cancer Center Specimen Respository (CCSR): a shared resource supported by the Cancer Center and the Department of Pathology and Laboratory Medicine
Research Histology Services: a histotechnologist dedicated to research is responsible for the work from all the Cancer Center clinical trials (including technical work and paperwork related to releasing material), work related to the Cancer Center Specimen Repository (CCSR), and histology services for researchers at the Cancer Center and in the Department of Pathology and Laboratory Medicine. To utilize the services of the research histotechnologist, please contact Regina Gandour-Edwards, M.D. or the Anatomic Pathology Manager Wendy Widmann.
Selected recent research publications by anatomic pathology faculty
Afify A, Lin-Cheng L, Howell L. Correlation of Cytologic Examination with ELISA Assays for Hyaluronan and Soluble CD44v6 Levels in Evaluation of Effusions, Diagn Cytopathol, In press.
Afify A, Pang L, Howell L. Diagnostic utility of CD44 standard, CD44v6, and CD44v3-10 Expression in adenocarcinomas presenting in serous fluids. Applied Immunohistochem Mol Bio, in press.
Francois CG, Brouha PC, Laurentin-Perez LA, Perez-Abadia G, Grossi FV, Barker JH, Hewitt CW, Kon M, Ramsamooj R, Maldonado C. Liver Transpl. 2006 Oct 6; in press.
Afify AM, Craig S, Paulino AF. Temporal variation in the distribution of hyaluronic acid, CD44s, and CD44v6 in the human endometrium across the menstrual cycle. Appl Immunohistochem Mol Morphol. 2006 Sep;14(3):328-33.
Ashton-Sager A, Paulino AF, Afify AM. GLUT-1 is preferentially expressed in atypical endometrial hyperplasia and endometrial adenocarcinoma. Appl Immunohistochem Mol Morphol. 2006 Jun;14(2):187-92.
Grigsby J, Leehey MA, Jacquemont S, Brunberg JA, Hagerman RJ, Wilson R, Epstein JH, Greco CM, Tassone F, Hagerman PJ. Cognitive impairment in a 65-year-old male with the fragile X-associated tremor-ataxia syndrome (FXTAS). Cogn Behav Neurol. 2006 Sep;19(3):165-71.
Greco CM, Berman RF, Martin RM, Tassone F, Schwartz PH, Chang A, Trapp BD, Iwahashi C, Brunberg J, Grigsby J, Hessl D, Becker EJ, Papazian J, Leehey MA, Hagerman RJ, Hagerman PJ. Neuropathology of fragile X-associated tremor/ataxia syndrome (FXTAS).Brain. 2006 Jan;129(Pt 1):243-55.
Iwahashi CK, Yasui DH, An HJ, Greco CM, Tassone F, Nannen K, Babineau B, Lebrilla CB, Hagerman RJ, Hagerman PJ. Protein composition of the intranuclear inclusions of FXTAS. Brain. 2006 Jan;129(Pt 1):256-71.
Vinall RL, Tepper CG, Shi XB, Xue LA, Gandour-Edwards R, de Vere White RW. The R273H p53 mutation can facilitate the androgen-independent growth of LNCaP by a mechanism that involves H2 relaxin and its cognate receptor LGR7. Oncogene. 2006 Mar 30;25(14):2082-93.
You Z, Shi XB, DuRaine G, Haudenschild D, Tepper CG, Lo SH, Gandour-Edwards R, de Vere White RW, Reddi AH. Interleukin-17 receptor-like gene is a novel antiapoptotic gene highly expressed in androgen-independent prostate cancer. Cancer Res. 2006 Jan 1;66(1):175-83.
Zwerdling T, Ducore J, Taylor D, West DC, Konia T. Rhabdomyoblastic pulmonary lesions in a patient with Wilms tumor: choristomas or metastases? Pediatr Blood Cancer. 2006 Mar;46(3):381-4.
Francois CG, Brouha PC, Laurentin-Perez LA, Perez-Abadia G, Grossi FV, Barker JH, Hewitt CW, Kon M, Ramsamooj R, Maldonado C. Vascularized lymph node transplantation induces graft-versus-host disease in chimeric hosts. Transplantation. 2006 May 27;81(10):1435-41.
Lakshminarayanan R, Konia T, Welborn J. Fibrous hamartoma of infancy: a case report with associated cytogenetic findings. Arch Pathol Lab Med. 2005 Apr;129(4):520-2.
Zarow C, Vinters HV, Ellis WG, Weiner MW, Mungas D, White L, Chui HC. Correlates of hippocampal neuron number in Alzheimer's disease and ischemic vascular dementia. Ann Neurol. 2005 Jun;57(6):896-903.
Aina OH, Marik J, Gandour-Edwards R, Lam KS. Near-infrared optical imaging of ovarian cancer xenografts with novel alpha 3-integrin binding peptide "OA02". Mol Imaging. 2005 Oct-Dec;4(4):439-47.
Aoki CA, Rossaro L, Ramsamooj R, Brandhagen D, Burritt MF, Bowlus CL. Liver hepcidin mRNA correlates with iron stores, but not inflammation, in patients with chronic hepatitis C. J Clin Gastroenterol. 2005 Jan;39(1):71-4.
Howell LP, Lin-Cheng L. Cytomorphology of common breast cancers. Clin Lab Med. 2005; 25:733-760.
Rodriguez RA, Konia T. Coccidioidomycosis of the tongue. Arch Pathol Lab Med. 2005 Jan;129(1):e4-6.
Afify A, Zhou H, Howell LP, Paulino A. Diagnostic utility of Glut-1 expression in cytologic evaluation of serous fluids. Acta Cytol 2005; 49:621-626
Fitzgerald JT, Sena MJ, Vandewalker KN, Johnson JR, Griffey SM, Tarantal AF, Barry PA, McChesney MB, Ramsamooj R, Perez RV. Occult pretransplantation systemic inflammation and posttransplantation vascular changes in a primate arterial allograft model. Transplantation. 2004 Aug 15;78(3):367-74.
Demos SG, Gandour-Edwards R, Ramsamooj R, deVere White R. Spectroscopic detection of bladder cancer using near-infrared imaging techniques. J Biomed Opt. 2004 Jul-Aug;9(4):767-71.
Demos SG, Gandour-Edwards R, Ramsamooj R, deVere White R. Near-infrared autofluorescence imaging for detection of cancer. J Biomed Opt. 2004 May-Jun;9(3):587-92.
Bader LJ, Carter KD, Latchaw RE, Ellis WG, Wexler JA, Watson JC. Simultaneous symptomatic Rathke's cleft cyst and GH secreting pituitary adenoma: a case report. Pituitary. 2004;7(1):39-44.
Howell LP, Tabnak F, Tudury AJ, Stoodt G. Role of Pap test terminology and age in the detection of carcinoma invasive and carcinoma in-situ in medically under-served California women. Diagn Cytopathol 2004; 30:227-234.
Howell LP, Zhou H, Wu W, Davis R. The significance of subclassifying high grade squamous intraepithelial lesions into moderate dysplasia/CIN II versus severe dysplasia/CINIII/CIS in The Bethesda System terminology. Diagn Cytopathol, 2004; 30:362-366.
Howell LP, Gandour-Edwards R, Folkins K, Davis R, Yasmeen S, Afify A. Adequacy evaluation of fine needle aspiration in the breast health clinic setting. Cancer Cytopathol 2004; 102: 295-301.