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Department of Pathology and Laboratory Medicine

Department of Pathology and Laboratory Medicine

Electron Microscopy

Diagnostic and Research Electron Microscopy Laboratory (DREM)

The mission of the laboratory is to aid the clinical and research community in their ultrastructural investigations, whether it is for research or diagnostics, using either transmission electron microscopy (TEM) or scanning electron microscopy (SEM).

We offer a full range of services including, consultation, sample preparation, training on instrumentation or documentation of ultrastructure by our staff. We are prepared to carry out all of the preparation and electron microscopy or share it with the investigator or the investigators designate.

Diagnostic electron microscopy is carried out under the direction of the submitting departmental Pathologist. Approximately 300 clinical samples a year are processed by the laboratory. The majority are surgical pathology specimens. About 100 of these are renal cases either for diagnosis of disease or for monitoring of transplant. The remaining cases are assessments for neoplasm, neuronal, neuro-muscular, or muscular diseases. Electron microscopy is conducted following CAP protocols. Digital images are captured and retained in the patients file. Backup compact disks are kept off-site at UC Davis Medical Center. Surgical Pathology Residents do a rotation through the lab during the course of their training.     

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