Chair of Medical Pathology and Laboratory Medicine
Chief Pathologist and Laboratory Director
Professor

Department of Medical Pathology and Laboratory Medicine
UC Davis Medical Center
PATH Building
4400 V Street
Sacramento, CA 95817

Chair of Pathology and Laboratory Medicine, Ralph Green is an expert in clinical pathology, with particular interest in diseases of the blood. He is internationally recognized for his research, which focuses on studying how deprivation of B-complex vitamins, iron and other nutritional elements affects the blood, cardiovascular system, nervous system, and the aging process. He has studied the role of nutrient deficiencies in dementia, coronary artery disease, and stroke, as well as other chronic degenerative diseases, including cancer. During his 35-year career, he has served as an adviser to numerous Governmental and International Agencies including the National Institutes of Health , U.S. Food and Drug Administration, Centers for Disease Control, and  American Heart Association. He recently served on an expert panel appointed by the Institute of Medicine of the National Academy of Sciences to recommend levels of daily intake for B-vitamins and currently is serving as a consultant to the World Health Organization. Dr Green serves on the editorial boards of several scientific journals.

• Green R.  Is it Time for B12 Fortification? What are the Questions?: Am J Clin Nutr Vol 89(suppl): S712-S717, 2009.

• Green R. Indicators for Assessing folate and Vitamin B12 Status and for Monitoring the Efficacy of Intervention Strategies.  Food and Nutrition Bulletin, Vol 29, No 2 (Suppl) S52-S63, 2008.

• Miller JW, Borowsky AD, Marple TC, McGoldrick ET, Dillard-Telm L, Young L JT, and Green R.  Folate, DNA methylation, and mouse models of breast tumorigenesis. Nutrition Reviews Vol. 66 (Suppl.1) S56-S61, 2008.

• Pront  R,  Margalioth E, Green R, Eldar-Geva T,  Maimoni Z,  Zimran A, Elstein D. Prevalence of Low Serum Cobalamin in Infertile Couples. Andrologia, Vol 41, ( 1): p 46-50, 2008.

• Garrod MG, Green R, Allen LH, Mungas DM, Jagust WJ, Haan MN, Miller JW.  Fraction of Total Plasma Vitamin B12 Bound to Transcobalamin Correlates with Cognitive Function in Elderly Latinos with Depressive Symptoms. Clinical Chemistry 54:7 1210-1217, 2008.

• Green R, Miller JW.  Vitamin B12.  In: Zempleni J, Rucker RB, Eds.  Handbook of Vitamins.  Boca Raton, FL: Taylor and Francis, pp. 413-457,  2007.

• Haan MN, Miller JW, Aiello AE, Whitmer RA, Jagust WJ, Mungas DM, Allen LH, Green R.  Homocysteine, B vitamins and incidence of dementia and cognitive impairment: results from the Sacramento Area Latino Study on Aging.  American Journal of Clinical Nutrition.  85(2): 511-517,  2007.

• Luchsinger JA, Tang MX, Miller J, Green R, Mayeux R.  Relation of Higher Folate Intake to Lower Risk of Alzheimer Disease in the Elderly  Arch. Neurol.  64(1): 86-92, 2007.

• Luchsinger JA, Tang MX, Miller J, Green R, Mehta, PD, Mayeux R.  Relation of Plasma Homocysteine to Plasma Amyloid Beta levels.  Neurochem. Res. 32: 775-781, 2007.

• Miller JW, Garrod MG, Rockwood AL, Kushnir MM, Allen LH, Haan MN, Green R. Measurement of total vitamin B12 and holotranscobalamin, singly and in combination, in screening for metabolic vitamin B12 deficiency. Clin. Chem, 52: 278-85, 2006.

• Carkeet C, Dueker SR, Lango J, Buchholz BA, Miller JW, Green R, Hammock B, Roth JR, Anderson PJ: Specific 14C-labeling of cobalamin and accelerator mass spectrometry underlie a quantitative test for B12 absorption in humans. Proceedings of the National Academy of Science of the United States of America, 103(15): 5694-5699, 2006.

• Campbell AK, Jagust WJ, Mungas DM, Miller JW, Green R, Haan MN, Allen LH: Low erythrocyte folate, but not plasma vitamin B-12 or homocysteine, is associated with dementia in elderly Latinos. J. Nutr. Health Aging. 9: 39-43, 2005.

• Green R, Miller JW. Vitamin B12 deficiency is the dominant nutritional cause of hyperhomocyteinemias in a folic acid-fortified population. Clin. Chem. Lab. Med. 43:1048-51, 2005.

• Ramos MI. Allen LH, Mungas DM, Jagust WJ, Haan MN, Green R, Miller JW. Low folate status is associated with impaired cognitive function and dementia in the Sacramento Area Latino Study on Aging. Amer. J. Clin. Nutr. 82: 1346-52, 2005.

• Luchsinger JA, Tang M-X, Shea S, Miller JW, Green R, Mayeux R: Plasma homocysteine levels and the risk of Alzheimer's disease. Neurology. 62: 1972-6, 2004.

• Ramos MI, Allen LH, Haan MN, Green R, Miller JW: Plasma folate concentrations are associated with depressive symptoms in elderly Latina women despite folic acid fortification. American Journal of Clinical Nutrition. 80:1024-28, 2004