Claudia M. Greco, M.D., M.S.

HSCP Clinical Professor of Pathology

Ph: Physician Referrals: 800-4-UCDAVIS (800-482-3284)

Center/Program Affiliation:

UC Davis MIND Institute

Clinical/Research Interests

Claudia M. Greco has a special interest in neuropathology. Her research interests lie in the investigation of Fragile X-related disorders, particularly in Fragile X Tremor-Ataxia Syndrome (FXTAS). Dr Greco also has an appointment with the UC Davis MIND Institute, where she directs the acquisition of brain tissue used to investigate the pathophysiology of neurodevelopmental disorders.



  • Neuropathology



  • M.D., Pennsylvania State University College of Medicine, Hershey, Pennsylvania, 1975
  • B.S., Case Western Reserve University, Cleveland, Ohio, 1971



University of California, San Diego, San Diego, California, 1975-78



University of California, San Diego, San Diego, California, 1978-80


Board Certifications

  • American Board of Pathology, Anatomic Pathology, 1980
  • American Board of Pathology, Neuropathology, 1980


Professional Memberships

  • American Academy of Neurology
  • American Association of Neuropathologists
  • San Francisco Neurological Society


Representative Publications

Tassone F, Greco CM, Hunsaker MR, Seritan AL, Berman RF, Gane LW, Jacquemont S, Basuta K, Jin LW, Hagerman PJ, Hagerman RJ. Neuropathological, clinical and molecular pathology in female fragile X premutation carriers with and without FXTAS. Genes Brain Behav. 2012 Mar 30. doi: 10.1111/j.1601-183X.2012.00779.x. [Epub ahead of print]

Greco CM, Navarro CS, Hunsaker MR, Maezawa I, Shuler JF, Tassone F, Delany M, Au JW, Berman RF, Jin LW, Schumann C, Hagerman PJ, Hagerman RJ. Neuropathologic features in the hippocampus and cerebellum of three older men with fragile X syndrome. Mol Autism. 2011 Feb 8;2(1):2.

Hunsaker MR, Greco CM, Spath MA, Smits AP, Navarro CS, Tassone F, Kros JM, Severijnen LA, Berry-Kravis EM, Berman RF, Hagerman PJ, Willemsen R, Hagerman RJ, Hukema RK. Widespread non-central nervous system organ pathology in fragile X premutation carriers with fragile X-associated tremor/ataxia syndrome and CGG knock-in mice. Acta Neuropathol. 2011 Oct;122(4):467-79. doi: 10.1007/s00401-011-0860-9. Epub 2011 Jul 23.

Hunsaker MR, Greco CM, Tassone F, Berman RF, Willemsen R, Hagerman RJ, Hagerman PJ. Rare intranuclear inclusions in the brains of 3 older adult males with fragile x syndrome: implications for the spectrum of fragile x-associated disorders. J Neuropathol Exp Neurol. 2011 Jun;70(6):462-9. doi: 10.1097/NEN.0b013e31821d3194.

Loesch DZ, Kotschet K, Trost N, Greco CM, Kinsella G, Slater HR, Venn A, Horne M. White matter changes in basis pontis in small expansion FMR1 allele carriers with parkinsonism. Am J Med Genet B Neuropsychiatr Genet. 2011 Jun;156B(4):502-6. doi: 10.1002/ajmg.b.31189. Epub 2011 Mar 28.

Wenzel HJ, Hunsaker MR, Greco CM, Willemsen R, Berman RF. Ubiquitin-positive intranuclear inclusions in neuronal and glial cells in a mouse model of the fragile X premutation. Brain Res. 2010 Mar 8;1318:155-66. Epub 2010 Jan 4.

Zhang L, Coffey S, Lua LL, Greco CM, Schafer JA, Brunberg J, Borodyanskaya M, Agius MA, Apperson M, Leehey M, Tartaglia N, Tassone F, Hagerman PJ, Hagerman RJ. FMR1 premutation in females diagnosed with multiple sclerosis. J Neurol Neurosurg Psychiatry. 2009 Jul;80(7):812-4.

Bobinski M, Greco CM, Schrot RJ. Giant intracranial medullary thyroid carcinoma metastasis presenting as apoplexy. Skull Base. 2009 Sep;19(5):359-62.

Bourgeois JA, Coffey SM, Rivera SM, Hessl D, Gane LW, Tassone F, Greco C, Finucane B, Nelson L, Berry-Kravis E, Grigsby J, Hagerman PJ, Hagerman RJ. A review of fragile X premutation disorders: expanding the psychiatric perspective. J Clin Psychiatry. 2009 Jun;70(6):852-62. Epub 2009 May 5.

Greco CM, Tassone F, Garcia-Arocena D, Tartaglia N, Coffey SM, Vartanian TK, Brunberg JA, Hagerman PJ, Hagerman RJ. Clinical and neuropathologic findings in a woman with the FMR1 premutation and multiple sclerosis. Arch Neurol. 2008 Aug;65(8):1114-6.

Chou F-L, Angelini C, Daentl D, Garcia C, Greco C, Hausmanowa-Petrusewicz I, et al: Calpain III mutation analysis of a heterogeneous limb-girdle muscular dystrophy population. NEUROLOGY 1999;52(5):1015-1020


To see if Claudia M. Greco is accepting new patients, or for assistance finding a UC Davis doctor, please call 800-2-UCDAVIS (800-282-3284).