Anthony Cheung, Ph.D.

Professor Emeritus
On Active Recall
Department of Pathology and Laboratory Medicine
UC Davis Medical Center
Research III Building, Suite 3400
4645 2nd Avenue
Sacramento, CA 95817
| Phone: | (916) 734-3855 |
| Clinic/Laboratory: | (916) 734-0571 |
| Pager: | (916) 762-8780 |
| Unit: | (916) 734-0695 |
| Fax: | (916) 734-2698 |
| Email: | anthony.cheung@ucdmc.ucdavis.edu |
Research Interests
- Hemorheology and biorheology
- Hemorrhagic/septic shock and artificial blood substitutes in shock treatment
- Vascular biology
- Microvascular abnormalities in vascular diseases
- Instrumentation design and application
- Computer-assisted intravital microscopy
- Medical informatics
- Cancer registry and interactive database
- Telepathology
Brief Biography
Anthony Cheung received a Bachelor of Science degree in Biology from Loyola University (Los Angeles, CA), Master of Arts degree in Biology/Zoology (Endocrinology and Biochemistry) from University of California (Los Angeles, CA) and a Doctor of Philosophy degree in Biology (Cell Physiology and Cell Biology) from University of California (Los Angeles, CA). In addition, he received his post-doctoral training in Engineering and Applied Science (Engineering Science, Fluidmechanics and Biomechanics) from the California Institute of Technology (Pasadena, CA).
Currently, Anthony Cheung is serving as Professor Emeritus on active recall in the Department of Pathology and Laboratory Medicine.
Since promotion to the rank of Full Professor in 1990, Anthony Cheung has received many awards and honor resolutions, including the 1990 UC Davis School of Medicine Joan Oettinger Memorial Award for excellence in pulmonary and cancer research, 2004 UC Davis School of Medicine Faculty Research Award for excellence in research, 1998 UC Davis Chancellor James H. Meyer Distinguished Achievement Award for excellence in teaching, research and university and community services, two UC Davis Professional Development Awards, and two honor resolutions -- citing his research performance and contribution to the State of California -- from the Senate and Assembly of the State of California. Anthony Cheung has served as a Visiting Professor at Universidad Del Mayab (Merida, Mexico), Cairo University (Cairo, Egypt) and Stanford University School of Medicine (Palo Alto, CA, USA).
Anthony Cheung is a member of six graduate groups in the UC Davis Graduate Division and is authorized to serve as major professor, thesis committee member and oral examination committee member in the following graduate groups:
- Comparative Pathology
- Microbiology
- Biomedical Engineering
- Immunology
- Medical Informatics
- Molecular, Cellular and Integrative Physiology
Anthony Cheung is a member of the American Society for Investigative Pathology, Microcirculatory Society of the United States of America, International Society of Artificial Cells, Blood Substitutes and Biotechnology, and Western Association of Physicians.
Recent and/or Relevant Publications
Chen PCY, Huang W, Stassinopoulos A and Cheung ATW. Effects of regulated hamster red blood cells on microcirculation. Artificial Cells, Blood Substitutes and Biotechnology (2008; in print).
Devaraj D, Cheung ATW, Jialal I, Griffen SG, Nguyen D, Glasser N and Aoki T. Evidence of increased inflammation and monocytic activity in patients with type-1 diabetes: Plausible role in microvascular complications. Diabetes 56: 2790-2796, 2007.
Cheung ATW, Driessen B, Chan DM, Duong PL, Chen PCY, Ramanujam S, Barbosa MA, Jahr JS, and Gunther RA. Comparison of treatment modalities for hemorrhagic shock. Artificial Cell, Blood Substitutes and Biotechnology 35: 173-190, 2007.
Driessen B, Zarucco L, Gunther RA, Burns PM, Lamb SV, Vincent SE, Boston RA, Jahr JS, and Cheung ATW. Effects of low volume Hemoglobin glutamer-2 (bovine) versus normal saline and arginine vasopressin resuscitation on systemic and skeletal muscle blood flow and oxygenation in a canine hemorrhagic shock model. Critical Care Medicine 35: 1-9, 2007.
Akakura N, Hoogland C, Takada YK, Liu FT, Cheung ATW, and Takada Y. The C-terminal globular domain of fibrinogen γ chain suppresses angiogenesis and tumor growth. Cancer Research 66: 9691-9697, 2006.
Cheung ATW, Duong PL, Driessen B, Chen PCY, Jahr JS, and Gunther RA. Systemic function, oxygenation and microvascular correlation during treatment of hemorrhagic shock with blood substitutes. Clinical Hemorheology and Microcirculation 34:325-334, 2006.
Cheung ATW. Blood flow abnormalities in sickle cell anemia. In: Reflection and Outlooks on Advances in Engineering Mechanics: In Honor of Professor Theodore Y.T. Wu (Edited by Chwang AT, Teng MH and Valentine DT), World Scientific Publications, New York, NY 2006.
Jahr JS, Osgood S, Rothenberg SJ, Steien E, Li QL, Bezdikian V, Butch AAW, Gunther RA, Cheung ATW, and Driessen B. Lactate interference by hemoglobin-based oxygen carriers (Oxyglobin®, Hemopure® and Hemolink™). Anesthesia and Analgesia 100:431-436, 2005.
Cheung ATW, Chan MS, Duong PL, Ramanujam S, Rangaswami A, Curl K, Franklin P, and Wun T. The real-time effects of Polaxamer 188 (Flocor™) on sickle cell vasoocclusive crisis. Journal of Investigative Medicine 52:402-406, 2004.
Embury SH, Matsui NM, Ramanujam S, Mayadas TN, Noguchi CT, Diwan BA, Mohandas N, and Cheung ATW. The contribution of endothelial P-selectin on microvascular flow of mouse sickle erythrocytes in vivo. Blood 104:3378-3385, 2004.
Khan AK, Jahr JS, Nesargi S, Rothenberg SJ, Tang Z, Cheung ATW, Gunther RA, Kost GJ, and Driessen B. Does lead interfere with hemoglobin-based oxygen carrier (HBOC) function: A pilot study of lead concentrations in three approved or tested HBOCs, and oxyhemoglobin dissociation with HBOCs and/or bovine blood with varying lead concentrations. Anesthesia and Analaagesia 96:1813-1820, 2003.
Weiss RH, Marshall D, Howard L, Corbacho AM, Cheung ATW, and Sawai ET. Suppression of breast cancer growth and angiogenesis by an antisense oligodeoxynucleotide to p21Wafl/Cip1. Cancer Letter 189:39-48, 2003.
Wun T, Cordoba M, Rangaswami A, Cheung ATW, and Paglieroni T. Activated monocytes and platelet-monocyte aggregates in patients with sickle cell disease. Clinical and Laboratory Haematology 24:81-88, 2002
Cheung ATW, Chen PCY, Larkin EC, Duong PL, Ramanujam S, Tablin F, and Wun T. Microvascular abnormalities in sickle cell disease: A computer-assisted intravital microscopy study. Blood 99:3999-4005, 2002.
Cheung ATW, Price AR, Duong PL, Ramanujam S, Gut J, Larkin EC, Chen PCY, and Wilson DM. Microvascular abnormalities in pediatric diabetic patients. Microvascular Research 63:252-258, 2002.
Cheung ATW. Metastasis and angiogenesis [Epitome; In Overview: The Contributions of Mouse Biology to Breast Cancer Research]. Journal of Comparative Medicine 52:12-31, 2002.
Cheung ATW, Ramanujam S, Greer DA, Kumagai L, and Aoki TT. Microvascular complications in the bulbar conjunctiva of patients with type-2 diabetes mellitus. Endocrine Practice 7:358-363, 2001.
Cheung ATW, Jahr JS, Driessen B, Duong PL, Chan MS, Lurie F, Golkaryeh MS, Kullar RK, and Gunther RA. The effects of hemoglobin-based oxygen carrier (Hemoglobin Glutamer-200 Bovine) on the microcirculation in a canine hypovolemia model: A non-invasive computer-assisted intravital microscopy study. Anesthesia and Analgesia 93:832-838, 2001.
Cheung ATW, Harmtz P, Wun T, Chen PCY, Larkin EC, Adams RJ, and Vinchinsky EP. Correlation of abnormal intracranial vessel velocity (measured by transcraanial Doppler ultrasonography) with abnormal conjunctival vessel velocity (measured by computer-assisted intravital microscopy) in sickle cell disease. Blood 97:3401-3404, 2001.
Cheung ATW, Perez RV and Chen PCY. Improvements in diabetic microangiopathy after successful simultaneous pancreas-kidney transplantation (SPK): A computer-assisted intravital microscopy study on the conjunctival microcirculation. Transplantation 68:927-932, 1999.
Cheung ATW, Shannon CM, Leshchinsky TV, and Larkin EC. Effects of chronic alcohol consumption on neutrophilic host defense in rats. Nutrition Research 19:1763-1775, 1999.
Embury SH, Mohandas N, Paszty C, Cooper P, and Cheung ATW. In vivo blood flow abnormalities in the transgenic knockout sickle cell mouse. Journal of Clinical Investigations 103:915-920, 1999.
Cheung ATW, Young LJT, Chen PCY, Chao CY, Ndoye A, Barry PA, Muller WJ, and Cardiff RD. Microcirculation and metastasis in a mouse mammary tumor model system. International Journal of Oncology 129:507-516, 1997.
Cheung ATW, Ayin SA and Kessell PR. Functional immaturity in neonatal polyumorphonuclear leukocytes of rhesus monkeys. Journal of Medical Primatology 25:84-88, 1996.
Cheung ATW, Chen PCY, Young LJT, Chao CY, Ndoye A, Kong A, and Cardiff RD. Angiogenesis and metastasis in breast tumors. Sixth World Congress for Microcirculation (Edited by Messmer K), pp. 23-26, 1996.
Cheung ATW and Gardner MB. Functional deficiency of polymorphonuclear leukocytes in simian acquired immune deficiency syndrome (SAIDS). American Journal of Veterinary Research 52:1523-1526, 1991.

