Robert Cardiff, M.D., Ph.D.
Department of Pathology and Laboratory Medicine
School of Medicine, UC Davis
Center for Comparative Medicine
University of California, Davis
County Road 98 and Hutchison Drive
Davis CA 95616
Also affiliated with the
Center for Comparative Medicine
Pathology of Genetically Engineered Mice
Dr. Cardiff is an academic surgical pathologist who received his bachelor’s degree (entomology) and Ph.D. (zoology) from UC Berkeley and his M.D. degree from UCSF. His pathology training was at University of Oregon, Portland. He has been at UC Davis since 1971 where he is a Distinguished Professor and was the Chair of the Department of Pathology and Laboratory Medicine from 1990 to 1996, Founding Director of the UC Davis Medical Center’s Center for Medical Informatics and is currently the Director of the UC Davis Center for Comparative Medicine’s Mutant Mouse Pathology Laboratory (MMPL).
His recent research interests have focused on experimental pathology of mouse mammary tumorigenesis. As director of the MMPF, he has developed an archive of samples from over 20,000 mutant mice from over 200 laboratories from 15 countries. This extensive collection serves as a basis for many of his current studies and provides him a unique niche in science as one of the few surgical pathologists in the world who combines a knowledge of R01 funded research, human pathology and mouse tumor pathology.
He currently is the Co-Chair of the Phenotyping Committee for the National Cancer Institute’s Mouse Models of Human Cancers Consortium and Immediate President and Chair of the Board of the International Association for Breast Cancer Research. His work has been recognized by various awards, most recently by the AAAS election as a fellow. His current research has emphasized mouse models of mammary precancer.
Chodosh LA, Cardiff RD. In Vivo Imaging of the Mammary Gland: The Shape of Things to Come. J Mammary Gland Biol Neoplasia. 2006 Nov 7.
Cardiff RD, Munn RJ, Galvez JJ. The Tumor Pathology of Genetically Engineered Mice: A New Approach to Molecular Pathology. In: Fox JG, Davisson MT, Quimby FW, Barthold SW, Newcomer CE, Smith AL, eds. The Mouse in Biomedical Research: Experimental Biology and Oncology Second ed. New York: Elsevier, Inc 2006:581-622.
Cardiff RD, Anver MR, Boivin GP, Bosenberg MW, Maronpot RR, Molinolo AA, et al. Precancer in mice: animal models used to understand, prevent, and treat human precancers. Toxicol Pathol. 2006;34(6):699-707.
Cardiff RD. Epithelial to Mesenchymal Transition Tumors: Fallacious or Snail's Pace? Clin Cancer Res. 2005 Dec 15;11(24 Pt 1):8534-7.
Cardiff RD, Rosner A, Hogarth MA, Galvez JJ, Borowsky AD, Gregg JP. Validation: the new challenge for pathology. Toxicol Pathol. 2004 Mar-Apr;32 Suppl 1:31-9.
Cardiff RD. Pathology of Mouse Models of Cancer. In: Holland EC, ed. Mouse Models of Human Cancer. Hoboken, New Jersey: Wiley-Liss, Inc 2004:15-30.
Cardiff RD. Mouse models of human breast cancer. Comp Med. 2003;53(3):250-3.
Rosner A, Miyoshi K, Landesman-Bollag E, Xu X, Seldin DC, Moser AR, et al. Pathway pathology: histological differences between ErbB/Ras and Wnt pathway transgenic mammary tumors. Am J Pathol. 2002;161(3):1087-97.
Cardiff RD, Moghanaki D, Jensen RA. Genetically engineered mouse models of mammary intraepithelial neoplasia. J Mammary Gland Biol Neoplasia. 2000 Oct;5(4):421-37.
Cardiff RD, Anver MR, Gusterson BA, Hennighausen L, Jensen RA, Merino MJ, et al. The mammary pathology of genetically engineered mice: the consensus report and recommendations from the Annapolis meeting. Oncogene. 2000;19(8):968-88.