PGYI Level:  PGY IV

UC Davis Health System
Department Of Otolaryngology
2521 Stockton Blvd., Suite 7200
Sacramento, CA 95817

Contact:
Email:  levi.ledgerwood@ucdmc.ucdavis.edu


EDUCATION

• JUNE 2008 – PRESENT UC DAVIS MEDICAL CENTER, SACRAMENTO, CA
  Department of Otolaryngology, Resident Physician
• AUG. 2003 – MAY 2008 MOUNT SINAI SCHOOL OF MEDICINE, NEW YORK, NY
  Doctor of Medicine, May 2008
• SEPT. 1997 – MAY 2001 AMHERST COLLEGE, AMHERST, MA
  Bachelor of Arts in Neuroscience, graduated Cum Laude
• FEB. 2000 – JULY 2000UNIVERSITY OF MELBOURNE, MELBOURNE, AUSTRALIA
  Study Abroad program through Beaver College
  

HONORS & AWARDS

• JUNE 2011 RESIDENT RESEARCH PRESENTATION AWARD
• JUNE 2009 TOP SCORE IN FACIAL PLASTICS PORTION OF IN-SERVICE AWARD
• MAY 2009 NEUROLOGICAL SURGERY INTERN OF THE YEAR AWARD
• JUNE 2005 – JUNE 2006 HOWARD HUGHES MEDICAL INSTITUTE MEDICAL STUDENT RESEARCH TRAINING FELLOWSHIP 
   

CERTIFICATIONS

• AUG. 2009 ACLS CERTIFICATION
• JULY 2009 PALS CERTIFICATION
• JUNE 2011 HIPAA RECERTIFICATION
• NOV. 2008 USMLE STEP III: PASSED
• AUG. 2011 BLS CERTIFICATION

RESEARCH EXPERIENCE

• SEPT. 2010 – PRESENT ARTIFICIAL MUSCLE FOR REANIMATION OF THE PARALYZED FACE
  Mentor: Travis T. Tollefson, M.D.
  UC Davis Medical Center, Department of Otolaryngology, Sacramento, CA
• JUNE 2009 – PRESENT MECHANISMS OF LYMPHATIC METASTASIS IN ORAL SCCA
  Mentor: D. Gregory Farwell, M.D.
  UC Davis Medical Center, Department of Otolaryngology, Sacramento, CA
• JUNE 2009 – PRESENT COSMETIC OUTCOMES FROM THE BICORONAL INCISION
  Mentor: E. Bradley Strong, M.D., Quang C. Luu, M.D.
  UC Davis Medical Center, Department of Otolaryngology, Sacramento, CA
• MAR. 2007 – MAY 2008 PSYCHOLOGICAL DISTANCE AND MEDICAL DECISION MAKING
  Mentor: Karen Zier, Ph.D.
  Mount Sinai School of Medicine & New York University, New York, NY
• JAN. 2004 – JAN. 2008 MOLECULAR MECHANISMS OF T-CELL MIGRATION
  Mentor: Jonathan S. Bromberg, M.D., Ph.D.
  Mount Sinai School of Medicine, New York, NY
  Research performed as HHMI Medical Student Research Fellow
• JUNE 2005 – JUNE 2007 PLASMACYTOID DENDRITIC CELLS AND TRANSPLANT TOLERANCE
  Mentors: Jordi C. Ochando, Ph.D., Jonathan S. Bromberg, M.D., Ph.D.
  Mount Sinai School of Medicine, New York, NY
  Research performed as HHMI Medical Student Research Fellow
• JUNE 2000 – JULY 2003 ALTERNATIVE ETIOLOGIES OF SCHIZOPHRENIA
  Mentor: Paul W. Ewald, Ph.D.
  University of Louisville, Dept. of Evolutionary Medicine, Louisville, KY
  

PUBLICATIONS IN PREPARATION

• Ledgerwood, L.G., Belafsky, P.C. Chronic Non-granulomatous supraglottitis: a rare and difficulty disease. Currently under review.
• Ledgerwood, L.G., Tinling, S.P., Senders, C., Wong-Foy, A., Prahlad, H., Tollefson, T.T. Artificial muscle for reanimation of the paralyzed face: durability and biocompatibility in an animal model. Currently under review.
  

PUBLICATIONS

• Ledgerwood, L.G., Rodriguez-Garcia, M., Parrilas, V., Yang, Y., Ginhoux, F., Tacke, F., Boros, P., Ding, Y., Chen, S., Merad, M., Randolph, G.J., Bromberg, J.S., Ochando, J.C. (2010). Gr1hi Monocytes Induce Tolerance to Cardiovascular Transplants. J Clin Investig. 120:2486-2496.
• Ledgerwood, L.G., Lal, G., Zhang, N., Garin, A., Esses, S.J., Ginhoux, F., Merad, M., Peche, H., Lira, S.A., Ding, Y., Yang, Y., He, X., Schuchman, E.H., Allende, M.L., Ochando, J.C., Bromberg, J.S. (2008). The sphingosine 1-phosphate receptor 1 causes tissue retention by inhibiting the entry of peripheral tissue T lymphocytes into afferent lymphatics. Nat Immunol.9:42-53.
• Ledgerwood, L.G., Ochando, J.C. (2007). Leukocyte Trafficking in Transplantation Tolerance: Home Sweet Home. Inmunología 26:42-50.
• Ochando, J.C., Ledgerwood, L.G., Yopp, A.C., Bromberg, J.S. (2006). Trafficking and migration in tolerance. Curr Opin Organ Transplant. 11:379-384.
• Yopp, A.C., Ledgerwood, L.G., Ochando, J.C., Bromberg, J.S. (2006). Sphingosine 1-phosphate receptor modulators: a new class of immunosuppressants. Clin Transplant. 20:788-795.
• Yopp, A.C., Ochando, J.C., Mao, M., Ledgerwood, L.G., Ding, Y., Bromberg, J.S.(2005).Sphingosine 1-phostphate receptors regulate chemokine driven transendothelial migration of lymph node but not splenic T cells.J Immunol. 175:2913-2924.
• Ledgerwood, L.G., Ewald, P.W., Cochran, G.M.(2003).Genes, Germs, and Schizophrenia:An Evolutionary Perspective.Perspect Biol Med.46:317-348.
  

ABSTRACTS

• Ledgerwood, L.G., Tollefson, T.T., Senders, C., Wong-Foy, A., Prahlad, H., Tinling, S.P. Artificial muscle for reanimation of the paralyzed face: durability and biocompatibility in an animal model. American Academy of Facial Plastic and Reconstructive Surgery Annual Meeting, San Francisco, CA, September 8-11, 2011. Oral presentation.
• Ledgerwood, L.G., Oliaei, S., Belafsky, P.C. Chronic non-granulomatous supraglottitis. Combined Otolaryngology Scientific Meeting, Chicago, IL, April 27-May 1, 2011. Poster Presentation.
• Ledgerwood, L.G. Peripheral tissue T lymphocyte entry into afferent lymphatics is regulated by sphingosine 1-phosphate receptor S1P1. Unidad de Inmunologia de Transplantes, Centro Nacional de Microbiologia, Instituto de Salud Carlos III, Madrid, Spain, September 28, 2007; Oral Presentation, Invited speaker.
• Ledgerwood, L.G., Lal, G., Esses, S.J., Ochando, J.C., Bromberg, J.S. Development of a novel assay for T cell lymphatic migration: role for sphingosine 1-phosphate receptor S1P1. American Transplant Congress, San Francisco, CA, May 5-9, 2007; Student Poster Presentation.
• Lal, G., Zhang, N., Ledgerwood, L.G., Esses, S.J., Bromberg, J.S. The sphingosine 1-phosphate receptor (S1PR) agonist FTY720 inhibits lymphatic transendothelial migration. American Transplant Congress, San Francisco, CA, May 5-9, 2007.
• Ledgerwood, L.G., Ochando, J.C., Yopp, A.C., Bromberg, J.S. Sphingosine 1-phosphate receptor activity is required for T cell migration from peripheral tissue into afferent lymph and lymph nodes. World Transplant Congress, Boston, MA, July 22-27, 2006; Student Oral Presentation.
• Ochando, J.C., Yang, Y., Ledgerwood, L.G., Garin, A., Ding, Y., Lira, S.A., Bromberg, J.S. High endothelial venules upregulate adhesion molecules to promote lymph node homing during tolerance to vascularized allografts. World Transplant Congress, Boston, MA, July 22-27, 2006.
• Ochando, J.C., Ledgerwood, L.G., Garin, A., Lira, S.A., Bromberg, J.S. Lymph node homing of alloantigen-presenting plasmacytoid dendritic cells mediates tolerance to vascularized grafts. Keystone Symposium: Chemokines and Chemokine Receptors, Snowbird, UT, January 15-20, 2006; Student Poster Presentation.
  

REVIEWING EXPERIENCE

• NOV. 2009 - PRESENT RESIDENT EDITOR, ENT JOURNAL
• SEPT. 2010 – PRESENT ASSOCIATE FACULTY, F1000 GROUP TEACHING EXPERIENCE
• SEPT. 2007 – MAY 2008 MOUNT SINAI STUDENT MENTOR FOR ASM II
• SEPT. 2007 – JAN. 2008 ANATOMY SENIOR TEACHING ASSISTANT & TUTOR
• JAN. 2006 – MAR. 2006 PHYSIOLOGY SENIOR TEACHING ASSISTANT & TUTOR
• SEPT. 2005 – DEC. 2005 ANATOMY SENIOR TEACHING ASSISTANT & TUTOR
• JAN. 2005 – MAR. 2005 PHYSIOLOGY TEACHING ASSISTANT & TUTOR
• JAN. 2005 – MAR. 2005 HISTOLOGY TEACHING ASSISTANT & TUTOR
  

PROFESSIONAL AFFILIATIONS

• DEC. 2008 – PRESENT AMERICAN CLEFT PALATE-CRANIOFACIAL ASSOCIATION
• SEPT. 2008 – PRESENT AMERICAN ACADEMY OF OTOLARYNGOLOGY
• AUG. 2003 – PRESENT AMERICAN MEDICAL ASSOCIATION