Clinical/Research Interests

Dr. Di Cesare focuses his clinical practice on adult reconstructive surgery on the hip and knee, and has earned an international reputation for complex primary and revision surgery, as well as the treatment of periprosthetic infections.

Dr. Di Cesare's clinical research interests include outcomes of total joint surgery, registries to track orthopaedic surgery outcomes, surgical navigation and alternative bearing surfaces for joint replacement. His basic research interests include arthritis biomarkers, mechanisms for chondrocyte and bone differentiation from stem cells, infection biomarkers, and mechanisms of cartilage breakdown in arthritis.

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Select Recent Publications:

Su ET, Kubiak EN, Dewal H, Hiebert R, Di Cesare PE. A proposed classification of supracondylar femur fractures above total knee arthroplasties. J Arthroplasty, 21(3):405-8, Apr 2006.

Pelham FR, Kubiak EN, Sathappan SS, Di Cesare PE. Topical negative pressure in the treatment of infected wounds with exposed orthopaedic implants. J Wound Care, 15(3):111-6, Mar 2006.

Liu CJ, Kong W, Ilalov K, Yu S, Xu K, Prazak L, Fajardo M, Sehgal B, Di Cesare PE. ADAMTS-7: A metalloproteinase that directly binds to and degrades cartilage oligomeric matrix protein. FASEB J, [Epub ahead of print], Apr 3, 2006.

Liu C, Kong W, Xu K, Luan Y, Ilalov K, Sehgal B, Yu S, Howell RD, Di Cesare PE. ADAMTS-12 associates with and degrades cartilage oligomeric matrix protein. J Biol Chem, [Epub ahead of print], Apr 12, 2006.

Iesaka K, Kubiak EN, Bong MR, Su ET, Di Cesare PE. Orthopedic surgical management of hip and knee involvement in patients with juvenile rheumatoid arthritis. Am J Orthop, 35(2):67-73, Feb 2006.

Fulkerson E, Della Valle CJ, Wise B, Walsh M, Preston C, Di Cesare PE. Antibiotic susceptibility of bacteria infecting total joint arthroplasty site. J Bone Joint Surgery Am, 88A:1231-1237, 2006.

Di Cesare PE, Frenkel SR, Carlson CS, Fang C, Liu C. Regional gene therapy for full-thickness articular cartilage lesions using naked DNA with a collagen matrix. J Orthop Res, [Epub ahead of print], Apr 11, 2006.

Kubiak EN, Moskovich R, Errico TJ, Di Cesare PE. Orthopaedic management of ankylosing spondylitis. J Am Acad Orthop Surg, 13:267-279, 2005.

Iesaka K, Kummer FJ, Di Cesare PE. Stress risers between two ipsilateral intramedullary stems. J Arthroplasty, 20(3):386-91, 2005.

Fajardo M, Di Cesare PE. Disease-modifying therapies for osteoarthritis: Current status. Drugs Aging, 22(2):141-61, 2005.