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Department of Obstetrics and Gynecology

Department of Obstetrics and Gynecology

The Northern California Children's Study Collaborative (NCCSC)

Co-PI: Professor Richard Sweet, M.D.

Co-Investigator: Assistant Research Professor Cheryl Walker, M.D.

Funding for the project: National Institute of Health, HHSN267200700035C


The National Children’s Study (NCS) will examine the effects of environmental influences on the health and development of 100,000 children across the United States, following them from before birth until age 21. The study defines “environment” broadly, taking a number of natural and man-made environmental, biological, genetic, and psychosocial factors into account. By studying children through their different phases of growth and development, researchers will be better able to understand the role these factors have on health and disease. Findings from the study will be made available as the research progresses, making potential benefits known to the public as soon as possible. UC Davis Health System was in 2007 selected as a new site for the National Children's Study and the Northern California Children Study Collaborative was formed. The new center will manage community engagement, local recruitment and data collection on 2,000 children in Sacramento and San Mateo counties. UC Davis will receive nearly $31.8 million over seven years for its portion of the study.


UC Davis is categorized as a Wave 1 study site. Currently the initial 7 sites (called Vanguard sites) are enrolling pregnant women in a geographic based household recruitment. In the spring and summer of 2010, 30 of the Wave 1 sites will be recruited to join the Vanguard pilot study. These additional sites will be added to evaluate 3 additional enrollment strategies: 1) Provider-based recruitment; 2) enhanced household recruitment; and 3) a high intensity/low intensity dynamic model (similar to long form and short form for the Census). The UC Davis site anticipates applying to participate in the provider based and enhanced household recruitment approaches. We are meeting with hospital and medical providers in Sacramento County. In addition, community outreach will commence in the geographic segments selected for Sacramento County.