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Effects of Fetal Bisphenol A Exposure on Oogenesis in Primates

Principal Investigator: Professor Catherine VandeVoort, PhD

Funding for the project:  National Institute of Health, RO1

 

Bisphenol A (BPA) is a widely used compound found in plastics and the lining of cans used for food that has been shown to have deleterious effects on offspring of mice when the pregnant dams are exposed to low doses. This project will measure BPA metabolism in non-pregnant and pregnant monkeys and determine if effects on eggs or ovaries are seen in developing offspring in primates as they are in mice. Because the dose used will be similar to current human blood levels of BPA, the results should have direct relevance to human health.