Faculty | Professors

Clinical & Research Interests

Charles S. DeCarli has a strong interest in behavioral neurology, with specific emphasis on dementing disorders, including degenerative dementias such as Alzheimer’s disease and frontal dementias. He also focuses on dementias related to movement disorders and vascular disease, as well as cognitive impairment after closed head injury. DeCarli’s research interests are divided into two areas: using neuroimaging techniques to understand the relationship between brain structure and function with aging and disease; and studying the role of brain antioxidant systems, primarily quinone oxidoreductase, on the pathophysiology and potential treatment of Alzheimer’s disease.

Education

George Washington University
Washington, D.C.
M.D. 1982

UC Santa Barbara
Santa Barbara, California
B.S. 1978

Residency

Strong Memorial Hospital
Rochester, New York
1984-87
Neurology

George Washington University Medical Center
Washington, District of Columbia
1982-84
Internal Medicine

Fellowships

National Institute on Aging
Bethesda, Maryland
1987-89
Laboratory of Neurosciences, Section on Brain Aging and Dementia

Board Certifications

American Board of Neurology and Psychiatry, 1991

Professional Memberships

American Academy of Neurology
American Association for the Advancement of Science
American Medical EEG Association
Society for Neuroscience

Select Recent Publications

Geroldi C, Laakso MP, DeCarli C, Beltramello A, Bianchetti A, Soininen H, Trabuchhi M, Frisoni GB. Apolipoprotein E Genotype and hippocampal asymmetry in Alzheimer's disease: A volumetric MRI study. JOURNAL OF NEUROLOGY, NEUROSURGERY & PSYCHIATRY 2000;68

GuoZ, Gupples LA, Kurz A, Auerbach S, Volicer L, Chui H, Green RC, Sandovnic AD, Duara R, DeCarli C, Johnson K, Go RC, Growdon JH, Haines JL, Kukull WA, Farrer LA. Head injury and the risk of Alzheimer disease in the MIRAGE study. NEUROLOGY 2000;54:1316-1

Geroldi c, Philajamaki M, Lassko MP, DeCarli C, Beltramello A, Bianchetti A, Soininen H, Trabucchi M, Frisoni G. APPE-e4 is associated with less frontal and more medical temporal lobe atrophy in AD. NEUROLOGY 1999;53:1825-1832

Swan GE, reed TE, Jack LM, Markee T, Miller GL, Wolf PA, DeCarli C, Carmelli D. Differential genetic influence for components of memory in aging adult twins. ARCHIVES OF NEUROLOGY 1999;56:1127-1132

Erkinjuntti T, Bowler JV, DeCarli CS, Fazekas F, Inzitari D, O'Brien JT, Pantoni L, Rockwood K, Scheltens P, Wahlund LO, Desmond DW. Imaging of static brain lesions in vascular dementia: Implications for clinical trials. ALZHEIMER'S DISEASE AND ASSOCIATED