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Investigators

Marta L. Marthas
Associate Adjunct Professor
California National Primate Research Center
Department of Pathology, Microbiology and Immunology

email: mlmarthas@ucdavis.edu

Specialty:

Macaque models of pediatric HIV/AIDS

* Transmission
* Pathogenesis
* Antiviral drugs and vaccines

Neonatal and infant primate vaccines and immune responses

Current Projects:

* Neonatal vaccine strategies to prevent AIDS
* Vaccine & microbicide strategies to prevent HIV infection/AIDS in pregnancy

Selected Publications: 1998, Van Rompay, K. K. A., C. J. Berardi, S. Dillard-Telm, R. P. Tarara, D. Canfield, C. J. Miller, C. R. Valverde, D. C. Montefiori, K. Stephano Cole, R. C. Montelaro, M. L. Marthas. Passive immunization of newborn rhesus macaques prevents oral SIV infection. Journal of Infectious Diseases, 177:1247-1259.

1999, Van Rompay, P. J. Dailey, R. Tarara, D. R. Canfield, N. L. Aguirre, J. M. Cherrington, P. D. Lamy, N. Bischofberger, N. C. Pedersen, and M. L. Marthas. Early short-term 9-[2-(phosphonomethoxy)-propyl] adenine (PMPA) treatment favorably alters subsequent disease course in simian immunodeficiency virus-infected newborn rhesus macaques. Journal of Virology, 73:2947-2955.

2001, Greenier, J. L., C. J. Miller, D. Lu, F. X. Lü, P. J. Dailey, K. Kunstman, S. M. Wolinsky, and M. L. Marthas. The route of simian immunodeficiency virus (SIV) inoculation determines the complexity, but not the identity, of viral variant populations that infect rhesus macaques. Journal of Virology 75:3753-3765.

Makori, N., A. F. Tarantal, F. X. Lü, T. Rourke , M.L. Marthas, M.B. McChesney, A.G. Hendrickx, C.J. Miller. Cytokine secreting cells, immunoglobulin secreting cells and CD5+ B-1 B Cells appear early in the development of the fetal rhesus monkey immune system. Clin. Diagnostic Lab. Immunol. 2003 10:140-53.