Laurel Alison Beckett, Ph.D.
Chief, Division of Biostatistics
Vice-Chair, Department of Epidemiology &
Preventive Medicine

email: labeckett@ucdavis.edu

Specialty: Biostatistics

Undergraduate Education: B.S., Mathematics, Pomona College, 1969

Other School: M.S., Statistics, Stanford University, 1969
Ph.D., Statistics, Stanford University, 1972

Professional Memberships: American Statistical Association, Biometric Society, Institute of Mathematical Statistics, California Tobacco-Related Disease Research Project, Study Sections for Clinical Trials (NIH, NIAMS).

Selected Publications: Dezube BJ, Pardee AB, Beckett LA, Ahlers CM, Allen-Ryan J, Ecto L, Anisowicz A, Sager R, Crumpacker CS. Cytokine Dysregulation in AIDS: In Vivo Overexpression of Tumor Necrosis Factor-a and Its Correlation with the Inflammatory Cytokine GRO. Journal of Acquired Immune Deficiency Syndromes, 1992; 5:1099-1104.

Siller L, Martin NL, Kostuchenko P, Rautonen J, Beckett LA, Cheng SC, Wara DW. Serum Levels of Soluble CD8, p24 Antigen, Neopterin, and Beta-2 Microglobulin as Indicators for Disease Progression in Children with AIDS under AZT Therapy. Journal of Acquired Immune Deficiency Syndromes, 1993; 7:369-373.

Dezube B, Pardee A, Chapman B, Beckett L, et al. Pentoxifylline decreases tumor necrosis factor expression and serum triglycerides in patients with AIDS. Journal of Acquired Immune Deficiency Syndromes, 1993; 6:787-794.

Japour AJ, Mayers DL, Johnson VA, Kuritzkes DR, Beckett LA, Arduino JM, Lane J, Black RJ, Reichelderfer PS, D'Aquila RD, Crumpacker CS, the RV-43 Study Group, and the AIDS Clinical Trials Group Virology Committee Resistance Working Group. A standardized peripheral blood mononuclear cell culture assay for the determination of drug susceptibilities of clinical Human Immunodeficiency Virus-1 (HIV-1) isolates. Antimicrobial Agents and Chemotherapy, 1993; 37:1095-1101.

De Gruttola V, Beckett LA, Coombs RW, Arduino JM, Balfour HH, Rasheed S, Hollinger FB, Fischl MA, Volberding P, and the AIDS Clinical Trials Group Virology Laboratories. Serum p24 Levels as an Intermediate End Point in Clinical Trials of Zidovudine in People Infected with Human Immunodeficiency Virus Type 1 (HIV-1). Journal of Infectious Diseases, 1994; 169:713-721.

Lieberman J, Fabry JA, Shankar P, Beckett L, Skolnik PR. Ex vivo expansion of HIV Type 1-specific cytolytic T cells from HIV type 1-seropositive subjects. AIDS Research and Human Retroviruses, 1995; 11:257-271.

Valentine FT, Kundu S, Haslett PAJ, Katzenstein D, Beckett L, Spino C, Borucki M, Vasquez M, Smith G, Korvick J, Kagan J, Merigan TC. A Randomized, Placebo-Controlled Study of the Immunogenicity of HIV RGP160 Vaccine in Human Immunodeficiency Virus-Infected Individuals with ³ 400 CD4 T Lymphocytes/mm3 (ACTG 137). Journal of Infectious Diseases, 1996; 173:1336-1346.

Beckett LA, Gilley DG, and Tancredi DJ. Modeling associations between change over time in multiple outcomes. Proceedings of the American Statistical Association, Section on Epidemiology, 1999; 106-110.

Beckett LA, Tancredi DJ. Parametric empirical Bayes estimates of disease prevalence using stratified samples from community populations. Statistics in Medicine, 2000; 19(5):681-695.

Beckett LA. Community-based studies of Alzheimer's disease: Statistical challenges in design and analysis. Statistics in Medicine, 2000; 19(11-12):1469-1480.

Hebert LE, Scherr PA, McCann JJ, Beckett LA, Evans DA. Is the risk of developing Alzheimer's disease greater for women than for men? Am J Epidemiol. 2001; 153(2):132-6.

Hebert LE, Beckett LA, Scherr PA, Evans DA. Annual incidence of Alzheimer disease in the United States projected to the years 2000 through 2050. Alzheimer Dis Assoc Disord. 2001; 15(4):169-73.

Wilson R, Beckett L, Barnes LL, Schneider JA, Back J, Evans DA, Bennett DA. Individual differences in rates of change in cognitive abilities of older persons. Psychol. and Aging. 2002; 17(2):179-93.

Wilson RS, Beckett LA, Bienias JL, Evans DA, Bennett DA. Terminal decline in cognitive function. Neurology 2003; 60:1782-1787.

Murray AM, Kaufmann J, Beckett LA, Bennet D, Mendes de Leon C, Evans D, Zhou L. A longintudinal Study of Prinsonism and disability to a community population of older people. The Journal of Gerontology: Medical Sciences. (in press).

Bienias JL, Beckett LA, Bennett DA, Wilson RS, Evans DA. Design of the Chicago Health and Aging Project (CHAP). Journal of Alzheimer's Disease (in press).

Beckett LA, Tancredi DJ, Wilson RS. Multivariate longitudinal methods for complex changes processes. Statistics in Medicine (in press).