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Investigators

Peter A. Barry
Associate Professor
Department of Pathology
Center for Comparative Medicine

email: pabarry@ucdavis.edu

Specialities:

  • Mechanisms of herpesvirus (rhesus cytomegalovirus - RhCMV) persistence and pathogenesis in non-human primates
  • Genetic immunization for chronic herpesviruses (RhCMV, herpes B virus) in non-human primates

Undergraduate Education:

  • University of Colorado, Boulder, CO
    B.A. (Molecular, Cellular, and Developmental Biology), 1976

Medical Education:

  • University of Utah, Salt Lake City, UT
    Ph.D. (Biology), 1985

Professional Memberships:

  • American Association for the Advancement of Science
    American Society for Microbiology
  • American Association of Immunologists

Fellowships:

  • Post Doctoral Fellow, 1987-1988, Department of Medical Pathology, University of California, Davis
  • Visiting Post Doctoral Fellow, 1988-1990, Department of Medical Pathology, University of California, Davis

Selected Publications: Spencer, J. V., Lockridge, K. M., Barry, P. A., Penfold, M. E. T., and T. J. Schall. 2002. Potent immunosuppressive activities of cytomegalovirus encoded IL-10. J. Virol. 76:1285-1292.

Sequar, G., Lakeman, F., Britt, W. J., Lockridge, K. M., Y. Yue, Zhou, S. S., R. P. Tarara, D. Canfield, R. D. Cardiff, and P. A. Barry. 2002. Experimental coinfection of rhesus macaques with rhesus cytomegalovirus and simian immunodeficiency virus: pathogenesis. J. Virol. 76:7661-7671.

Chang, W. L., Tarantal, A. F., Zhou, S.-S., Borowsky, A. D., and P. A. Barry. 2002. A recombinant rhesus cytomegalovirus expressing green fluorescent protein retains wild-type replication and pathogenic potential in fetal macaques. J. Virol. 76:9493-9504.

Jones, B. C., Logsdon, N., Josepheson, N., Cook, J., Barry, P. A., and M. R. Walter. 2002. Crystal structure of human cytomegalovirus IL-10 bound to soluble human IL-10R1. Proc. Natl. Acad. Sci (USA). 99:9404-9409.

Huff, J., R. Eberle, J. Capitanio, S. S. Zhou, and P. A. Barry. 2002. Development and Application of a Real-Time PCR Assay for Detection of B Virus and Rhesus Cytomegalovirus in Rhesus Macaques. J. Genl. Virol. 84:83-92.

Huff, J., R. and P. A. Barry. 2002. B Virus Infection in Humans and Macaques: The Potential for Zoonotic Human Disease. Emerging Infectious Diseases. 9:246-250.

Chang, W. L. and P. A. Barry. 2003. Cloning of the full-length rhesus cytomegalovirus genome as an infectious and self-excisable bacterial artificial chromosome for analysis of viral pathogenesis. J. Virol. 77:5073-5083.

Wasson, K. and P. A. Barry. 2003. Molecular characterization of Encephalitozoon intestinalis (Microspora) replication kinetics in a murine intestinal cell line. J. Eukaryotic Microbiol. 50:169-174.

Andrade, M. R., J. Yee, P. A. Barry, A. Spinner, J. A. Roberts, Pe. H. Cabello, J. P. Leite, N. W. Lerche. 2003. Prevalence of Antibodies to Selected Viruses in a Long-term Closed Breeding Colony of Rhesus Macaques (Macaca mulatta) in Brazil. Amer. J. Primatol. 59:123-128.

Kassis, N., C. L. Hale, M. Simon, M. Elliott, A. Gomez-Yafal, J. Lifson, R. C. Desrosiers, F. Wang, P. Barry, M. Mach, R. P. Johnson, and A. Kaur. 2003. Direct relationship between suppression of cytomegalovirus (CMV)-specific immunity and emergence of CMV disease in AIDS. J. Virol. 77:5749-5758.

Barry, P. A. Efficient Electroporation of Mammalian Cells in Culture. 2003. in Gene Delivery to Mammalian Cells: Methods and Protocols, W. Heiser, ed.

Penfold M.E.T., T.L. Schmidt, D.J. Dairaghi, P. A. Barry, and T. J. Schall. 2003. Characterization of the rhesus CMV US28 locus. J. Virol. 77:10404-10413.

McCormick, A. L., A. Skaletskaya, P. A. Barry, E. S. Mocarski, and V. S. Goldmacher. 2003. Differential Function and Expression of the Viral Inhibitor of Caspase 8-induced Apoptosis (vICA) and the Viral Mitochondria-localized Inhibitor of Apoptosis (vMIA) Cell Death Suppressors. Conserved in Primate and Rodent Cytomegaloviruses. Virol. in press.

Yue, Y., Zhou, S. S., and P. A. Barry. 2003. Antibody responses to rhesus cytomegalovirus glycoprotein B in naturally infected rhesus macaques. J. Genl. Virol. in press.