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Fragile X Syndrome
Early Visual Processing Deficits in Fragile X and Autism
Presenter: Susan Rivera, Ph.D.
Affiliation: UC Davis MIND Institute
Date: August 6, 2010
Length: 1:25:35
Summary: Overview of early sensory development and neural underpinnings of visual processing strengths and weaknesses.
Developing Neurobehavioral Biomarkers for Targeted Treatment in Fragile X from Human and Animal Studies
Lecturers: Robert F. Berman, Ph.D., Susan Rivera, Ph.D., & Tony J. Simon, Ph.D.
Affiliation: UC Davis MIND Institute
Date: January 29, 2010
Length: 1:29:32
Synopsis: An overview of integrated neuroscience research efforts to study Fragile X-associated tremor ataxia (FXTAS). Specifically, the presentation will describe how studies in human FXTAS patients and basic science findings in transgenic mouse models of FXTAS have been integrated so that each informs the other to accelerate the pace of scientific discovery.
Nonverbal Cognitive Impairments in Various Neurodevelopmental Disorders: Implications for Learning
Presenter: Tony Simon, Ph.D.
Affiliation: UC Davis MIND Institute
Date: August 6, 2010
Length: 1:20:16
Summary: Emerging research on overlapping patterns of cognitive function in fragile x, Turner, and chromosome 22q11.2 deletion sydromes and their implications for intervention.
Developing Neurobehavioral Biomarkers for Targeted Treatment in Fragile X from Human and Animal Studies
Lecturers: Robert F. Berman, Ph.D., Susan Rivera, Ph.D., & Tony J. Simon, Ph.D.
Affiliation: UC Davis MIND Institute
Date: January 29, 2010
Length: 1:29:32
Synopsis: An overview of integrated neuroscience research efforts to study Fragile X-associated tremor ataxia (FXTAS). Specifically, the presentation will describe how studies in human FXTAS patients and basic science findings in transgenic mouse models of FXTAS have been integrated so that each informs the other to accelerate the pace of scientific discovery.
A New Age of Treatment for Fragile X Syndrome
Presenter: Randi Hagerman, M.D.
Affiliation: UC Davis MIND Institute
Date: August 7, 2009
Length: 58:05
Summary: Neurobiological abnormalities in Fragile X Syndrome, review of targeted treatments available and the mechanisms by which they work, with preliminary data regarding minocycline, fenobam, and R-baclofen.
New Targeted Treatments for Fragile-X Syndrome
Presenter: Randi Hagerman, M.D.
Affiliation: UC Davis MIND Institute
Date: August 8, 2008
Length: 1:20:21
Fragile X: A Family Affair
Presenters: Paul Hagerman, M.D.,Ph.D. & Randi Hagerman, M.D.
Affiliation: UC Davis MIND Institute
Date: January 17, 2008
Length: 1:41:28
Synopsis: It's hard to imagine, but defects in a single gene can cause mental impairment in children, premature ovarian failure in women and dementia in older adults. That gene -- the fragile X gene -- is the research focus of two MIND Institute investigators who are leading the way in discovering the molecular foundations of and new treatments for the broad spectrum of fragile X-related disorders. Hear more about what their work has revealed about the causes and outcomes of fragile X syndrome, their plans for new treatment trials and the benefits of their discoveries for understanding neurodevelopmental and neurodegenerative disorders
Three Disorders, One Explanation? The Case of Cognitive Impairments in Fragile X Syndrome, Turner and Chromosome 22q11.2 Deletion Syndrome
Presenter: Tony Simon, Ph.D.
Affiliation: UC Davis MIND Institute
Date: Oct 16, 2008
Length: 1:07:28
Synopsis: Chromosome 22q11.2 deletion, Turner, and fragile X syndromes are different genetic disorders producing weakness in visuospatial, visuomotor and numerical cognition. 7 to 14 year old children with these disorders were studied to see if a common mechanism might be at work. Dr. Simon will present results from experimental cognitive and brain imaging studies that explain how children with these disorders think about space, time and number and suggest designs for therapeutic interventions.
What We Learn About Autism from Studying Fragile X Syndrome
Presenters: David Hessl, Ph.D., Lisa Cordeiro
Affiliation: UC Davis MIND Institute
Date: Jan 22, 2009
Length: 54:22
Synopsis: Individuals with autism and fragile X syndrome share many symptoms and there may be common neurobiological abnormalities underlying these symptoms. Dr. Hessl will share recent findings from his laboratory and others focusing on this topic and discuss implications that the overlapping features may have for the treatment of both conditions.
Presenter: Leonard Abbeduto, Ph.D.
Affiliation: University of Wisconsin, Madison
Date: May 9, 2007
Synopsis: Click for Abstract
4PM Lecture: Language Problems in Fragile X Syndrome: From Behavioral Phenotypes to Family Contexts
4PM Length: 1:11:47
6PM Lecture: Understanding the Communication Challenges of Youth with Fragile X Syndrome
6PM Length: 1:16:44
Research Guiding Psycho-pharmacologic Intervention in Fragile X and Fetal Alcohol Syndrome
Presenter: Randi Hagerman, M.D., F.A.A.P.
Affiliation: UC Davis MIND Institute
Date: August 4, 2005
Length: 1:03:18
