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Brain and Environmental Training Towards Emotional Resilience

Presenter: Mani N. Pavuluri, M.D., Ph.D.

Affiliation: University of Illinois at Chicago

Date: April 8, 2015

Synopsis: Click for Abstract

Length: 1:06:25


The Neurexin Enigma: Towards understanding synapse formation and neuropsychiatric disorders

Presenter: Thomas C. Sudhof, M.D.

Affiliation: Stanford University

Date: January 14, 2015

Synopsis: Click for Abstract

Length: 1:22:49


The Molecular Basis of Cognitive Deficits in Down Syndrome: What we know and what we need to know

Presenter: Katheleen Gardiner, Ph.D.

Affiliation: University of Colorado, Denver

Date: October 8, 2014

Synopsis: Click for Abstract

Length: 1:22:07

The RASopathies: Ras pathway dysregulation in development

Presenter: Katherine Rauen, M.D., Ph.D.

Affiliation: UC Davis MIND Institute

Date: August 8, 2014

Length: 1:16:05

Summary: The RASopathies are a group of clinically related developmental disorders which are caused by germline mutations in genes that encode regulators of the Ras/mitogen activated protein kinase (MAPK) pathway. The Ras/MAPK pathway plays an essential role in the regulation of the cell cycle, differentiation, growth and cell senescence, all of which are critical to normal development.

Development of the Brain’s Functional Networks

Presenter: Bradley L. Schlaggar, M.D., Ph.D.

Affiliation: Washington University School of Medicine

Date: April 10, 2013

Synopsis: Schlaggar Abstract »

Length: 59:21

Releasing the Brake on Synaptic Plasticity: Immune genes moonlighting in neurons

Presenter: Carla J. Shatz, Ph.D.

Affiliation: Stanford University

Date: December 14, 2011

Synopsis: Schatz Abstract »

Length: 1:02:50

Neural Signatures of Atypical Brain Development in Autism

Presenter: Kevin A. Pelphrey, Ph.D.

Affiliation: Yale University

Date: October 13, 2010

Synopsis: Pelphrey Abstract »

Length: 1:18:39

Epigenetics and the Environment: Why Grandmothers are Important

Presenter: Dian Baker, Ph.D., APRN-BC, PNP

Affiliation: California State University, Sacramento

Date: August 6, 2010

Length: 1:14:49

Summary: Understanding epigenetics, the contributions of the maternal environment, and possible mechanism for prevention of behavioral disorders.

Oxidative Stress and the Metabolic Pathology of Autism

Presenter: S. Jill James, Ph.D.

Affiliation: University of Arkansas for Medical Sciences

Date: June 9, 2010

Synopsis: James Abstract »

Length: 1:23:42

The Genetic Epidemiology of Autism

Presenter: John N. Constantino, M.D.

Affiliation: Washington University School of Medicine

Date: April 14, 2010

Synopsis: Constantino Abstract »

Length: 1:13:40

Psychosocial and Biological Markers of Stress in the Lives of Mothers of Adolescents and Adults with Autism

Presenter: Marsha Mailick Seltzer, Ph.D.

Affiliation: University of Wisconsin, Madison

Date: February 10, 2010

Synopsis: Seltzer Abstract »

Length: 1:23:18

Developing Neurobehavioral Biomarkers for Targeted Treatment in Fragile X from Human and Animal Studies

Lecturers: Robert F. Berman, Ph.D., Susan Rivera, Ph.D., & Tony J. Simon, Ph.D.

Affiliation: UC Davis MIND Institute

Date: January 29, 2010

Length: 1:29:32

Synopsis: An overview of integrated neuroscience research efforts to study Fragile X-associated tremor ataxia (FXTAS). Specifically, the presentation will describe how studies in human FXTAS patients and basic science findings in transgenic mouse models of FXTAS have been integrated so that each informs the other to accelerate the pace of scientific discovery.

The Fetal Androgen Theory of Autism

Presenter: Simon Baron-Cohen, Ph.D.

Affiliation: Cambridge University

Date: December 9, 2009

Synopsis: Baron-Cohen Abstract »

Length: 1:14:38

Antibodies and the Brain: Lessons from Lupus

Presenter: Betty A. Diamond, M.D.

Affiliation: Feinstein Institute for Medical Research

Date: November 9, 2009

Synopsis: Diamond Abstract »

Length: 1:05:07

The Many Faces of Autism: From Behavior to Biology

Presenter: Robin Hansen, M.D.

Affiliation: UC Davis MIND Institute

Date: August 7, 2009

Length: 50:48

Summary: Current research on the heterogeneity of autism spectrum disorders in terms of both behavior and biology, and advances in our knowledge of etiology and application for treatments.

A New Age of Treatment for Fragile X Syndrome

Presenter: Randi Hagerman, M.D.

Affiliation: UC Davis MIND Institute

Date: August 7, 2009

Length: 58:05

Summary: Neurobiological abnormalities in Fragile X Syndrome, review of targeted treatments available and the mechanisms by which they work, with preliminary data regarding minocycline, fenobam, and R-baclofen.

Update in Pharmacologic Treatments of ASDs

Presenter: Robert Hendren, D.O.

Affiliation: UC San Francisco

Date: August 7, 2009

Length: 55:18

Summary: Symptoms, co-morbidities and monitoring guidelines to inform decisions regarding benefits/risks associated with use of pharmacologic agents to treat behavioral symptoms of autism spectrum disorders.

Presenter: Adele Diamond, Ph.D.

Affiliation: University of British Columbia

Date: June 10, 2009

Synopsis: Adele Abstract »

4PM Lecture: Prefrontal Cortex and Developmental Neuropsychology: Genetic and Environmental Influences
4PM Length: 1:24:05

6PM Lecture: Cognitive Control in Young Children and Ways to Improve It
6PM Length: 1:23:58

Presenter: Thomas Bourgeron, Ph.D.

Affiliation: Institut Pasteur - Paris

Date: May 13, 2009

Synopsis: Bourgeron Abstract »

4PM Lecture: Synaptic and Clock Genes in Autism Spectrum Disorders
4PM Length: 59:50

6PM Lecture: Toward a Better Understanding of the Genetic Susceptibility to Autism Spectrum Disorders
6PM Length: 1:20:03

Immunologic Abnormalities in ASD & Convergence of Genetic and Environmental Mechanisms Conferring Autism Risk

Presenters: Daniel Braunschweig, Isaac Pessah, Ph.D.

Affiliation: UC Davis MIND Institute

Date: April 16, 2009

Length: 1:32:00

Synopsis: Dan Braunschweig discusses the current research regarding the immune abnormalities found in children with autism and their potential correlation with the development of autism. Dr. Pessah focusses on how certain genetic markers may make the body more susceptible to certain environmental triggers which could cause developmental problems like autism.

Presenter: Andrew Zimmerman, M.D.

Affiliation: Kennedy Krieger Institute

Date: April 8, 2009

Synopsis: Zimmerman Abstract »

4PM Lecture: Effects of Fever in Autism: Clues to Pathogenesis and Treatment
4PM Length: 54:08

6PM Lecture: The "Fever Effect" and Search for the Holy Grail in Autism
6PM Length: 53:46

Presenter: Pat Levitt, Ph.D.

Affiliation: Vanderbilt University

Date: January 14, 2009

Synopsis: Levitt Abstract »

4PM Lecture: The MET Receptor Tyrosine Kinase and Autism Risk
4PM Length: 1:19:38

6PM Lecture: Where Are We With the Autisms?
6PM Length: 1:23:17

Presenter: Ann Graybiel, Ph.D.

Affiliation: Massachusetts Institute of Technology

Date: October 8, 2008

Synopsis: Graybiel Abstract »

4PM Lecture: Learning and Memory Mechanisms of the Basal Ganglia
4PM Length: 1:23:40

6PM Lecture: Our Habitual Lives: How the Brain Makes and Breaks Habits
6PM Length: 1:40:41

How Blood Gene Expression Profiles in Children with Neurodevelopmental Disorders Can Assist Clinical Diagnosis

Presenter: Lisa Lit, M.A.

Affiliation: UC Davis MIND Institute

Date: August 7, 2008

Length: 51:20

Cortisol: A Clue into the Rhythms and Reactions of Children with Autism

Presenter: Blythe Corbett, Ph.D.

Affiliation: UC Davis MIND Institute

Date: July 17, 2008

Length: 1:40:47

Synopsis: Cortisol is often referred to as "the stress hormone" because it is secreted during the "fight or flight" response and it is involved in various stress-related changes. Learn more about the work of a MIND Institute researcher who is investigating cortisol as a biological marker of stress and dysregulation in children with autism. The presentation will include recent findings and comparisons of cortisol to social and emotional behavior, brain structure and function, and the symptoms of autism and other neurodevelopmental disorders.

Fragile X: A Family Affair

Presenters: Paul Hagerman, M.D.,Ph.D. & Randi Hagerman, M.D.

Affiliation: UC Davis MIND Institute

Date: January 17, 2008

Length: 1:41:28

Synopsis: It's hard to imagine, but defects in a single gene can cause mental impairment in children, premature ovarian failure in women and dementia in older adults. That gene -- the fragile X gene -- is the research focus of two MIND Institute investigators who are leading the way in discovering the molecular foundations of and new treatments for the broad spectrum of fragile X-related disorders. Hear more about what their work has revealed about the causes and outcomes of fragile X syndrome, their plans for new treatment trials and the benefits of their discoveries for understanding neurodevelopmental and neurodegenerative disorders

Presenter: Annette Karmiloff-Smith, Ph.D.

Affiliation: University of London

Date: December 12, 2007

Synopsis: Karmiloff-Smith Abstract »

4PM Lecture: Understanding Disorders of Mind and Brain in Children: The Necessity of a Developmental Perspective
4PM Length: 58:08

6PM Lecture: Modules, Genes, and Evolution: Lessons from Developmental Disorders
6PM Length: 54:54

Presenter: Karen F. Berman, M.D.

Affiliation: National Institute of Mental Health

Date: November 14, 2007

Synopsis: Berman Abstract »

4PM Lecture: Translating Between Genes, Brain, and Behavior with Neuroimaging: Neural Mechanisms in Schizophrenia and Williams Syndrome
4PM Length: 1:13:39

6PM Lecture: How Genes Work in the Brain: Lessons from Neuroimaging of Schizophrenia and Williams Syndrome
6PM Length: 1:03:24

Presenter: Marco Iacoboni, M.D., Ph.D.

Affiliation: University of California, Los Angeles

Date: October 10, 2007

Synopsis: Iacoboni Abstract »

4PM Lecture: The Problem of Other Minds: Intersubjectivity and Mirror Neurons
4PM Length: 1:07:24

6PM Lecture: The Mirror Neuron Hypothesis of Autism
6PM Length: 1:02:59

Limbic-Hypothalamic-Pituitary-Adrenocortical (LHPA) Axis in Children with Autism

Presenter: Blythe Corbett, Ph.D.

Affiliation: UC Davis MIND Institute

Date: August 3, 2007

Length: 1:32:39

The Reshaping of the Neurobiology of Autism

Presenter: Nancy Minshew, M.D.

Affiliation: University of Pittsburgh School of Medicine

Date: August 2, 2007

Length: 1:09:45

Presenter: Susan Bookheimer, Ph.D.

Affiliation: University of California, Los Angeles

Date: April 11, 2007

Synopsis: Bookheimer Abstract »

4PM Lecture: Neural Basis of Social Communication Deficits in Autism: Insights from Functional Imaging
4PM Length: 1:04:27

6PM Lecture: Understanding Emotions in Others: Brain Imaging of Social Communication in Autism
6PM Length: 1:03:04

Presenter: Joseph Piven, M.D.

Affiliation: University of North Carolina at Chapel Hill

Date: March 14, 2007

Synopsis: Piven Abstract »

4PM Lecture: Towards Defining the Autism Phenotype
4PM Length: 1:08:57

6PM Lecture: Imaging the Developing Brain: Insights into the Pathogenesis of Autism
6PM Length: 1:06:19

Is Neuroimmunity Involved in the Pathogenesis of Autism

Presenter: Carlos A. Pardo, M.D.

Affiliation: Johns Hopkins University

Date: January 9, 2007

Synopsis: Pardo Abstract »

Length: 1:11:13

Presenter: Stephen J. Suomi, Ph.D.

Affiliation: National Institute of Child Health & Human Development

Date: December 13, 2006

Synopsis: Suomi Abstract »

4PM Lecture: Aggression, Serotonin and Gene-Environment Interactions in Rhesus Monkeys and Primates
4PM Length: 1:06:42

6PM Lecture: Up-tight, Laid-back and Jumpy Monkeys
6PM Length: 1:00:40

Presenter: Arthur L. Beaudet, M.D.

Affiliation: Baylor College of Medicine

Date: November 8, 2006

Synopsis: Beaudet Abstract »

4PM Lecture: A Mixed Epigenetic/Genetic and DeNovo/Inherited (MEGDI) Model for Autism
4PM Length: 58:40

6PM Lecture: If the Incidence of Autism is Increasing, What Could be the Cause?
6PM Length: 56:44

The "Three Strikes" Hypothesis: How Genes, Environment and Bad Timing May Converge to Disrupt Neural Development and Function

Presenter: Mady Hornig, M.D., M.A.

Affiliation: Columbia University

Date: November 2, 2006

Length: 54:56

Synopsis: Dr. Hornig discusses a hypothesis that certain genetic factors create a susceptibility to other environmental and temporal factors that could possibly lead to abnormalities in neural development.

Understanding Immunological and Neurobiological Susceptibilities Contributing to Autism Risk

Presenter: Isaac Pessah, Ph.D.

Affiliation: UC Davis MIND Institute

Date: November 2, 2006

Length: 47:45

Synopsis: Dr. Pessah lectures on how environmental factors are affecting neurobiological and immunological mechanisms in children with autism.

Presenter: David L. Pauls, Ph.D.

Affiliation: Harvard Medical School & Massachusetts General Hospital

Date: October 11, 2006

Synopsis: Pauls Abstract »

4PM Lecture: The Genetics of Gilles de la Tourette Syndrome
4PM Length: 1:01:43

6PM Lecture: Gilles de la Tourette Syndrome and Obsessive Compulsive Disorder: What is the Relationship?
6PM Length: 1:09:54

Structural and Functional Neuroimaging of the Amygdala in Children with Autism

Presenter: Blythe Corbett, Ph.D.

Affiliation: UC Davis MIND Institute

Date: August 11, 2006

Length: 1:06:03

Neurocognitive Profiles of Children from Several Developmental Disorder Populations

Presenter: Tony Simon, Ph.D.

Affiliation: UC Davis MIND Institute

Date: August 10, 2006

Length: 1:18:02

Presenter: Charles Nelson, Ph.D.

Affiliation: Harvard University & Boston Children's Hospital

Date: May 10, 2006

Synopsis: Nelson Abstract »

4PM Lecture: The Development and Neural Bases of Face Processing
4PM Length: 59:34

6PM Lecture: The Effects of Early Institutionalization on Brain and Behavioral Development: A Model System for Studying Neural Plasticity
6PM Length: 1:04:52

Presenter: T. Conrad Gilliam, Ph.D.

Affiliation: University of Chicago

Date: November 9, 2005

Synopsis: Gilliam Abstract »

4PM Lecture: Genetic and Genomic Mapping of Autism Loci
4PM Length: 1:10:57

6PM Lecture: Genomics, Pathways, and Disease Genes
6PM Length: 1:01:25