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UC Davis MIND Institute

UC Davis MIND Institute

CABIL Research Projects

We currently have travel funds to assist families across North America who would like to take part in our research studies. For information please contact the study coordinator at (916) 703-0408 or cabil@ucdmc.ucdavis.edu. 

Brain Development and Learning Difficulties in Chromosome 22q11.2 Deletion (VCFS/DiGeorge) Syndrome

We are carrying out a study on the problems that some children have with thinking, reasoning and learning about space, time and number information and similar kinds of thinking. The study is funded by the National Institutes of Health, which is the main organization that gives money for research in the USA. Dr. Tony Simon would like to invite your 7 to 14 year old child with chromosome 22q11.2 deletion syndrome (VCFS/DiGeorge) to be part of the study. Many children with chromosome 22q11.2 deletion syndrome score lower on tests of math and similar thinking abilities compared to how they score on tests of verbal abilities. We are studying the brain and how it produces this profile of thinking. Once we know more we hope to find ways to reduce the learning problems that some children have by developing a range of therapeutic interventions.

Children who take part in the study will play a few computer games, do paper and pencil tests, and have pictures taken of their brain using an MRI machine. MRI scans do not involve any radiation. All of the activities are safe, fun and painless. All testing is for research purposes only, is at no cost to families, and includes a generous thank-you gift for your child. If needed, we have some funds to help you with travel and lodging for your trip to Sacramento. All personal and medical information is kept private and safe. If you and your child would like to take part we will answer all of your questions and give you more information over the phone first. The actual study involves 2 sessions of about 4-5 hours each, including breaks for lunch/snacks.

If you would like to find out more about taking part in the study and helping us learn about mind and brain development in children like your own, please click here.

Stress- and Anxiety-Related Hormone Regulation and Implications for Behavior in Chromosome 22q11.2 Deletion (VCFS/DiGeorge) Syndrome

Drs. Elliott Beaton and Tony Simon at the MIND Institute at University of California, Davis are carrying out an important study on the problems that some children have dealing with stress resulting from illness, trouble with schoolwork, and difficulties with peers and family.  The findings from this study will help us better understand why some children with chromosome 22q11.2 deletion syndrome develop serious psychiatric problems later in life and why some do not.

Stress and anxiety have real effects on health and well-being. Children with genetic disorders such as chromosome 22q11.2 deletion syndrome (22q11.2DS) are vulnerable to psychiatric illness in adolescence and young adulthood. However, very little is known about how stress affects the likelihood of such negative outcomes. From an early age, children with the deletion often have extensive medical concerns and, as he or she gets older and enters the school system, his or her emotional, cognitive, and social challenges can become more apparent in the context of increasing social and academic expectations further adding to feelings of stress and anxiety.

There are two parts to the study and you and your child can take part in one or both parts.  One part will happen at the MIND Institute if your child is participating in one of the other ongoing studies at CABIL.  Children will be asked to spit some saliva into a test tube both before and after their practice MRI session.  You and your child will then be asked to do paper and pencil tests about how they have been feeling, thinking, and acting over the last couple of weeks. The child’s guardian(s) will also asked to answer questions about how the child has been thinking feeling and acting and also about how they are feeling themselves. The second part of the study is done by you in your home.  We will ask you to have your child spit saliva into special plastic collection tubes five times on two weekdays and one weekend day. We can measure stress hormones and immune function from the saliva samples. All testing is for research purposes only and is at no cost to families. We will send you a saliva sample collection kit and detailed instructions. Also, you and your child will then be asked to do paper and pencil tests about how they have been feeling, thinking, and acting. The child’s guardian(s) will also asked to answer questions about how the child has been thinking feeling and acting and also about how they are feeling themselves. It’s easy and painless and we will provide a prepaid mailer to send the samples back to the MIND Institute.

All personal and medical information is kept private and safe. If you and your child would like to take part we will answer all of your questions and give you more information over the phone first.

If you would like to find out more about taking part in the study and helping us learn about mind and brain development in children like your own, please click here.

Brain Development and Learning Difficulties in Klinefelter or XXX Syndrome

We are carrying out a study on the problems that some children have with thinking, reasoning and learning about space, time and number information and similar kinds of thinking. The study is funded by the National Institutes of Health, which is the main organization that gives money for research in the USA. Dr. Tony Simon would like to invite your 7 to 14 year old son with Klinefelter or daughter with XXX syndrome to be part of the study. Many children with these syndrome score lower on tests of verbal abilities compared to how they score on tests of math and similar thinking abilities. We are studying the brain and how it produces this profile of thinking. Once we know more we hope to find ways to reduce the learning problems that some children have by developing a range of therapeutic interventions.

Children who take part in the study will play a few computer games, do paper and pencil tests, and have pictures taken of their brain using an MRI machine. MRI scans do not involve any radiation. All of the activities are safe, fun and painless. All testing is for research purposes only, is at no cost to families, and includes a generous thank-you gift for your child. If needed, we have some funds to help you with travel and lodging for your trip to Sacramento. All personal and medical information is kept private and safe. If you and your child would like to take part we will answer all of your questions and give you more information over the phone first. The actual study involves 2 sessions of about 4-5 hours each, including breaks for lunch/snacks.

If you would like to find out more about taking part in the study and helping us learn about mind and brain development in children like your own, please click here.