David J. Segal, Ph.D.

David J. Segal, Ph.D.

Professor, UC Davis Genome Center, Department of Biochemistry and Molecular Medicine, Pharmacology, MIND Institute, UC Davis School of Medicine
4512 GBSF
451 Health Sciences Drive
Davis, CA 95616


Phone:  530-754-9134
E-mail:  djsegal@ucdavis.edu  

Dr. Segal’s research focuses on engineering custom DNA-binding proteins and their application toward improving public health. He has over 60 publications on the use of targetable nucleases to make precise changes to the DNA of living cells, and the use of artificial transcription factors to activate or repress specific genes of interest.  His work has been supported by grants from the NIH, DOD, and the foundations for Angelman, Prader-Will, and Rett syndromes.  Dr. Segal sits on the scientific advisory board of the Foundation for Angelman Syndrome Therapeutics and the Foundation for Pitt Hopkins Syndrome. He holds joint appointments in the Department of Biochemistry and Molecular Medicine, the Department of Pharmacology, the MIND Institute, and the Genome Center, where he is the Associate Director of Genomics. He has mentored 18 undergraduate, 11 graduate, and six post-doctoral researchers, placing him in an excellent position to advise trainees for this program.


B.S., Biology, Cornell University, 1989
Ph.D., Biochemistry, University of Utah, 1996