Joseph Anderson, Ph.D. - IDDRC Investigator

Joseph Anderson, Ph.D.

Assistant Professor, Department of Internal Medicine, Stem Cell Program, UC Davis School of Medicine
IRC Building
2921 Stockton Blvd, Room 1300
Sacramento, CA 95817 


Phone: 916-703-9300 / Fax:  916-703-9310
E-mail: joseph.anderson@ucdmc.ucdavis.edu

Areas of Interest

HIV Stem Cell Gene Therapy, Tay-Sachs, Sandhoff Disease

Research

Joseph Anderson is an Assistant Professor in the Department of Internal Medicine and is faculty in the UC Davis Stem Cell Program. Dr. Anderson’s research focuses on developing new therapies based on stem cell and gene therapy techniques. His recent work involving the development of a stem cell gene therapy strategy for HIV has progressed towards IND status and is currently being evaluated by the FDA. His new endeavors include a research project for Tay-Sachs disease using genetically modified blood stem cells.

Current IDDRC Projects

  • Expression of HexA/HexB via blood cells to cure Tay-Sachs disease, CTSF

Recent Representative Publications

Stem cell transplantation in the context of HIV--how can we cure HIV infection? Bauer G, Anderson JS. Expert Rev Clin Immunol. 2014 10(1):107-116.

CD25 preselective anti-HIV vectors for improved HIV gene therapy. Kalomoiris S, Lawson J, Chen RX, Bauer G, Nolta JA, Anderson JS. Hum Gene Ther Methods. 2012 23(6):366-375.

Fighting HIV with stem cell therapy: one step closer to human trials? Anderson JS, Bauer G. Expert Rev Anti Infect Ther. 2012 10(10):1071-1073.

Generation of an HIV-1-resistant immune system with CD34(+) hematopoietic stem cells transduced with a triple-combination anti-HIV lentiviral vector. Walker JE, Chen RX, McGee J, Nacey C, Pollard RB, Abedi M, Bauer G, Nolta JA, Anderson JS. J Virol. 2012 86(10):5719-5729.

Generation of HIV-1 resistant and functional macrophages from hematopoietic stem cell-derived induced pluripotent stem cells. Kambal A, Mitchell G, Cary W, Gruenloh W, Jung Y, Kalomoiris S, Nacey C, McGee J, Lindsey M, Fury B, Bauer G, Nolta JA, Anderson JS. Mol Ther. 2011 19(3):584-593.