About Us
Paul Ashwood, Ph.D.
University of California, Davis
UC Davis M.I.N.D. Institute
2805 Wet Lab Building
Sacramento, CA 95817
Tel. (916) 703-0405
pashwood@ucdavis.edu
UC Davis M.I.N.D. Institute
2805 Wet Lab Building
Sacramento, CA 95817
Tel. (916) 703-0405
pashwood@ucdavis.edu
Education
University College London, London, U.K., B.Sc.
Imperial College London, London, U.K., M.Sc.
King’s College London, London, U.K., Ph.D.
Imperial College London, London, U.K., M.Sc.
King’s College London, London, U.K., Ph.D.
Research Interests
Dr. Ashwood, an immunologist, is a recent recruit to the M.I.N.D. Institute. Much of his current work is directed at characterizing the role of the immune system in autism. Recognizing the highly complex and interconnected nature of the immune and central nervous systems, Ashwood is interested in exploring whether the health of one system is integral to the healthy development of the other. His initial efforts at the M.I.N.D. Institute will be to fully characterize the immune response in children with autism. Ashwood's original research in his native England involved identification of a new variant of inflammatory bowel disease found in some cases of autism.
Selected Publications
Ashwood P, Harvey R, Verjee T, Wolstencroft R, Thompson RPH, Powell JJ. Competition between IL-1, IL-1ra and TGF modulates the response of the ELA4.NOB-1/CTLL bioassay Implications for clinical investigations. Inflammation Research 53(2): 60-65, 2004.
Machado M, Ashwood P, Thomson MA, Sim R, Walker-Smith JA, Murch SH. Spontaneous TH1 cytokine production by intestinal but not circulating T cells in infants and young children with and without food allergies. Allergy 59:346-35312, 2004.
Ashwood P, Harvey R, Verjee T, Wolstencroft R, Thompson RPH, Powell JJ. Functional Interactions between mucosal IL-1, IL-1ra and TGF in Ulcerative Colitis. Inflammation Research 53(2):53-59, 2004.
Torrente F, Anthony A, Heuschkel RB, Thomson MA, Ashwood P, Murch SH. Focal enhanced gastritis in regressive autism with features distinct from Crohn’s disease and Helicobacter pylori gastritis. American Journal of Gastroenterology 99(4);598-605, 2004.
Ashwood P, Van de Water JA. A review of autism and the immune response. Clin Develop Immunology 11(2);165-174, 2004.
Thomson M, Afzal N, Ashwood P, Hall S, Frutscher-Ravens A, Swain CP. Endoluminal Gastroplication in children with significant gastro-oesophageal reflux disease. Gut 53(12):1745-1750, 2004.
Ashwood P, Anthony A, Torrente F, Wakefield AJ. Spontaneous mucosal lymphocyte cytokine profiles in children with regressive autism and gastrointestinal symptoms: mucosal immune activation and reduced counter regulation. J Clin Immunol 24(6):664-673, 2004.
Ashwood P, Van de Water J. Is Autism an autoimmune disease? Autoimmunity Reviews 3(7-8):557-562, 2004.
Puleston J, Cooper M, Murch S, Makh S, Ashwood P, Bingham A, Green H, Moss P, Dhillon A, Gelinas A, Pounder R, Platt A. A distinct subset of chemokines, induced in colonic epithelium by IL-1, dominates the mucosal chemokine response in ulcerative colitis. Alimentary Pharmacol Therapeutics 21(2):109-120, 2005.
Machado M, Ashwood P, Thomson MA, Sim R, Walker-Smith JA, Murch SH. Spontaneous TH1 cytokine production by intestinal but not circulating T cells in infants and young children with and without food allergies. Allergy 59:346-35312, 2004.
Ashwood P, Harvey R, Verjee T, Wolstencroft R, Thompson RPH, Powell JJ. Functional Interactions between mucosal IL-1, IL-1ra and TGF in Ulcerative Colitis. Inflammation Research 53(2):53-59, 2004.
Torrente F, Anthony A, Heuschkel RB, Thomson MA, Ashwood P, Murch SH. Focal enhanced gastritis in regressive autism with features distinct from Crohn’s disease and Helicobacter pylori gastritis. American Journal of Gastroenterology 99(4);598-605, 2004.
Ashwood P, Van de Water JA. A review of autism and the immune response. Clin Develop Immunology 11(2);165-174, 2004.
Thomson M, Afzal N, Ashwood P, Hall S, Frutscher-Ravens A, Swain CP. Endoluminal Gastroplication in children with significant gastro-oesophageal reflux disease. Gut 53(12):1745-1750, 2004.
Ashwood P, Anthony A, Torrente F, Wakefield AJ. Spontaneous mucosal lymphocyte cytokine profiles in children with regressive autism and gastrointestinal symptoms: mucosal immune activation and reduced counter regulation. J Clin Immunol 24(6):664-673, 2004.
Ashwood P, Van de Water J. Is Autism an autoimmune disease? Autoimmunity Reviews 3(7-8):557-562, 2004.
Puleston J, Cooper M, Murch S, Makh S, Ashwood P, Bingham A, Green H, Moss P, Dhillon A, Gelinas A, Pounder R, Platt A. A distinct subset of chemokines, induced in colonic epithelium by IL-1, dominates the mucosal chemokine response in ulcerative colitis. Alimentary Pharmacol Therapeutics 21(2):109-120, 2005.