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Department of Medical Microbiology and Immunology

Department of Medical Microbiology and Immunology

Jay V. Solnick, M.D., Ph.D.

Center for
Comparative Medicine
Davis Campus
(530) 752-1333

Research Interests

Bacterial pathogenesis, bacterial and host gene transcription in the non-human primate model of Helicobacter pylori.

Lab Page: http://ccm.ucdavis.edu/faculty/solnick/


Representative Publications

Solnick, J.V., Canfield, D.R., Hansen, L.M., and Torabian, S.Z. Immunization with recombinant Helicobacter pylori urease in specific pathogen free rhesus monkeys (Macaca mulatta), Infection and Immunity, 2000, 68: 2560-65.

Mattapallil, J.J., Dandekar, S., Canfield, D.R., and Solnick, J.V. A predominant Th-1 type of immune responseis induced early during acute Helicobacter pylori infection in rhesus macaques, Gastroenterology, 2000, 118: 307-15.

Solnick, J.V. and Schauer, D.B. Emergence of the Helicobacter Genus in the Pathogenesis of gastric and enterohepatic diseases, Clinical Microbiology Reviews, 2001, 14: 59-97.

Solnick, J.V. and Schauer, D.B. Emergence of the Helicobacter Genus in the Pathogenesis of gastric and enterohepatic diseases, Clinical Microbiology Reviews, 2001, 14: 59-97.

Solnick JV, Hansen LM, Canfield,DR and Parsonnet J.  Determination of the infectious dose of Helicobacter pylori during primary and secondary infection in the rhesus monkey (Macaca mulatta), Infect Immun, 2001, 69: 6887-92.

Solnick JV, Hansen LM, Canfield DR. The [14]-C Urea Breath Test is Not Sensitive for Detection of Acute Helicobacter pylori Infection in Rhesus Monkeys (Macaca mulatta), 2002, 47:298-303.

Fernandez, KR, Hansen, LR, Vandamme, P, Beaman, BL., and Solnick, JV.  Captive rhesus monkeys are commonly infected with Helicobacter cinaedi.  J Clin Microbiol, 2002, 40: 1908-12.

Solnick, JV.  Clinical significance of Helicobacter species other than H. pylori.  Clin Infect Dis, 2003, 36:349-54.

Dandekar, S., Reay E, Taylor, EM, and Solnick, JV. Apoptosis of gastric lymphocytes in Helicobacter pylori-infected rhesus macaques.  Dig Dis Sci, 2003, 48: 1073-80.

Solnick, JV, Chang, K, Canfield, DR and Parsonnet.  Natural acquisition of Helicobacter pylori in newborn rhesus macaques.  J. Clin. Microbial.  2003, 41: 5511-16.

Solnick, JV, Hansen, LM, Salama, NR, Boonjakuakul, JK, and Syvanen, M.  Modification of Helicobacter pylori outer membrane protein expression during experimental infection of rhesus macaques.  Proc Natl Acad Sci USA, 2004, 101: 2106-2111.

Boonjakuakul, JK, Syvanen, M, Suryaprasad, A, Bowlus, C, and Solnick, JV.  A transcription profile of Heliocbacter pylori in the human stomach reflects its physiology in vivo.  J Infect Dis, 2004, 190: 946-956.

Huff JL, Hansen, LM, and Solnick, JV.  A gastric transcription  profile of Heliocbacter pylori infection in the rhesus macaque.   Infect Immun, 2004, 72: 5216-5226.

Ayala, G, Chihu, L, Perales, G., Fierros-Zarate, G, Hansen, LM, Solnick, JV, and Sanchez, J.  Quantitation of Helicobacter pylori cytotoxin mRNA by real-time RT-PCR shows a wide expression range that does not correlate with promoter sequences.  Microb Pathogen, 2004, 37: 163-167.

O’Rourke, JL, Solnick, JV, Neilan, BA, Seidel, K, Hayter, R, Hansen, LM, and Lee, A. Description of "Candidatus Helicobacter heilmannii" based on DNA sequence analysis of 16S rDNA and urease genes. Int J Syst Evol Microbiol, 2004, 54: 2203-2211.

Terio, KA, Munson, L, Marker, L, Aldridge, BM, and Solnick, JV.  Comparison of Helicobacter spp. in cheetahs (Acinonyx jubatus) with and without gastritis.  J Clin Microbiol, 2005, 43: 229-234.