Richard Pollard, M.D.
Chief, Infectious Diseases
UCD Med Center
Sacramento Campus

Representative Publications

Pollard RB, Rockstroh JK, Pantaleo G, Asmuth DM, Peters B,Lazzarin A, Garcia F, Ellefsen K, Podzamczer D, van Lunzen J, Arastéh K, Schürmann D, Clotet B, Hardy WD, Mitsuyasu R, MoyleG, Plettenberg A, Fisher M, Fätkenheuer G, Fischl M, Taiwo B,Baksaas I, Jolliffe D, Persson S, Jelmert O, Hovden AO, SommerfeltMA, Wendel-Hansen V, and Sørensen B. Safety and efficacy of the peptide-based therapeutic vaccine for HIV-1, Vacc-4×: a phase 2 randomised, double-blind, placebo-controlled trial. The Lancet, 2014;14(4):291-300.

Brown J, Burger H, Weiser B, Pollard RB, Li XD, Clancy LJ, Baumann R, Rogers A, Hamdan HB, Pesana RL, and Kagan RM. A genotypic HIV-1 proviral DNA coreceptor tropism assay: characterization in viremic subjects. AIDS Research and Therapy, 2014;11(14): 1-7.

Rodriguez B, Asmuth DM, Matining RM, Spritzler J, Jacobson JM, Mailliard RB, Li XD, Martinez AI, Tenorio AR, Lori F, Lisziewicz J, Yesmin S, Rinaldo CR, and Pollard RB. Safety, tolerability, and immunogenicity of repeated doses of dermavir, a candidate therapeutic HIV vaccine, in HIV-infected patients receiving combination antiretroviral therapy: results of the ACTG 5176 trial. JAIDS, 2013;64(4): 351-359.

Nagy LH, Grishina I, Macal M, Hirao LA, Hu WK, Sankaran- Walters S, Gaulke CA, Pollard RB, Brown J, Suni M, Baumler AJ, Ghanekar S, Marco ML, Dandekar S. Chronic HIV infection enhances the responsiveness of antigen presenting cells to commensal lactobacillus. PLoS ONE, 2013;8(8): e72789.

Kalayjian RC, Spritzler J, Matining RM, Fiscus SA, Gross BH, Francis IR, Pollard RB, Lederman MM, and Landay A. Older HIV-infected patients on antiretroviral therapy have B-cell expansion and attenuated CD4 cell increases with immune activation reduction. AIDS, 2013; 27(10): 1563-1571.

Enkhmaa B, Anuurad E, Zhang W, Abbuthalha A, Li XD, Dotterweich W, Pollard RB, Asmuth DM, Berglund L. HIV disease activity as a modulator of lipoprotein(a) and allele-specific apolipoprotein(a) levels. Arteriosclerosis, Thrombosis, and Vascular Biology, 2013;33(2): 387-392.

Allen ME, Brown J, Karakas SE, and Pollard RB. Refractory AIDS cholangiopathy: metabolic complications and the role of plasmapheresis. AIDS, 2013;27(7): 1193–1194.

Shaw JM, Hunt PW, Critchfield JW, McConnell DH, Garcia JC, Pollard RB, Somsouk M, Deeks S, Shacklett BL. HIV+ Viremic Slow Progressors Maintain Low Regulatory T-Cell Numbers in Rectal Mucosa but Exhibit High T-cell Activation. AIDS Research and Human Retroviruses, 2013;29(1): 172-177.

Hulgan t, Robbins GK, Kalams SA, Samuels DC, Grady B, Shafer R, Murdock DG, Selph D, Haas DW, Pollard RB for the AIDS Clinical Trials Group. T Cell Activation Markers and African Mitochondrial DNA Haplogroups among Non-Hispanic Black Participants in AIDS Clinical Trials Group Study 384. PLoS One, 2012;7(8): e43803.

Hayes TL, Asmuth DM, Critchfield JW, Knight TH, McLaughlin BE, Yotter T, McConnell DH, Garcia JC, Pollard RB, Shacklett BL. Impact of highly active antiretroviral therapy initiation on CD4+ T-cell repopulation in duodenal and rectal mucosa. AIDS, 2012;27: 867-877

Ferre AL, Lemongello D, Hunt PW, Morris MM, Garcia JC, Pollard RB, Yee HFJr, Martin JN, Deeks SG, and Shacklett BL. Immunodominant HIV-Specific CD8 +T-Cell Responses Are Common to Blood and Gastrointestinal Mucosa, and Gag-Specific Responses Dominate in Rectal Mucosa of HIV Controllers. Journal of Virology, 84(19): 10354-10365, 2010.

Lennox JL, Dejesus E, Berger DS, Lazzarin A, Pollard RB, Ramalho Madruga JV, Zhao J, Wan H, Gilbert CL, Teppler H, Rodgers AJ, Barnard RJ, Miller MD, Dinubile MJ, Nguyen BY, Leavitt R, Sklar P, and the STARTMRK Investigators. Raltegravir Versus Efavirenz Regimens in Treatment-Naive HIV-1-Infected Patients: 96-Week Efficacy, Durability, Subgroup, Safety, and Metabolic Analyses. Journal of Acquired Immune Deficiency Syndrome, 2010 Apr 15. [Epub ahead of print], 2010.

Smith K, Zheng L, Bosch R, Margolis D, Tenorio A, Napolitano L, Saag M, Connick E, Lawrence J, Gross B, Francis I, Valdez H, Wang R, Muurahainen N, Stocker V, Pollard RB.. Treatment with recombinant growth hormone is associated with enhanced CD4 lymphocyte reconstitution in HIV-infected subjects with incomplete immune reconstitution on HAART--results of adult AIDS clinical trial group protocol (AACTG) 5174. AIDS Res Human Retrovir, 26(4): 425-432, 2010.

Kalayjian R, Machekano R, Rizk N, Robbins G, Gandhi R, Rodriguez B, Pollard RB, Lederman M, and Landay A. Pre-treatment levels of soluble receptors and interleukin-6 are associated with HIV disease progression in subjects treated with highly active antiretroviral therapy. Journal of Infectious Diseases, 201(12): 1796-1805, 2010.

Asmuth DM, Murphy RL, Rosenkranz SL, Lertora JJ, Kottilil S, Cramer Y, Chan ES, Schooley RT, Rinaldo CR, Thielman N, Li XD, Wahl SM, Shore J, Janik J, Lempicki RA, Simpson Y, Pollard RB; and the AIDS Clinical Trials Group A5192 Team.. Safety, tolerability, and mechanisms of antiretroviral activity of pegylated interferon Alfa-2a in HIV-1-monoinfected participants: a phase II clinical trial. Journal of Infectious Diseases, 201(11): 1686-1696, 2010.

Schacker T, Bosch R, Bennett K, Pollard RB, Robbins G, Collier A, Gulick R, Spritzler J, and Mildvan D. Measurement of Naive CD4 Cells Reliably Predicts Potential for Immune Reconstitution in HIV. Journal of Acquired Immune Deficiency Syndrome, 54(1): 59-62, 2010.

Crawford K, Spritzler J, Kalayjian R, Parsons T, Landay A, Pollard RB, Stocker V, Lederman M, Flexner C.. Age-related changes in pharmacokinetic parameters of the HIV protease inhibitor lopinavir. AIDS Res Human Retrovir, 2009.

Gupta SK, Komarow L, Gulick RM, Pollard RB, Robbins GK, Franceschini N, Szczech LA, Koletar SL, and Kalayjian RC. Proteinuria, Creatinine Clearance, and Immune Activation in Antiretroviral-Naive HIV-Infected Subjects. The Journal of Infectious Diseases, 200: 614-618, 2009.

Yoshida T, Kobayashi M, Li XD, Pollard RB, and Suzuki F. Inhibitory effect of glycyrrhizin on the neutrophil-dependent increase of R5 HIV replication in cultures of macrophages. Immunology and Cell Biology, 2009(Jun 16): Epub ahead of print, 2009.

Meier A, Chang JJ, Chan ES, Pollard RB, Sidhu HK, Kulkarni S, Wen TF, Orellana L, Mildvan D, Bazner S, Streeck H, Alter G, Lifson JD, Carrington M, Bosch RJ, Robbins GK, and Altfeld M. Sex differences in the TLR-mediated response of pDCs to HIV-1 are associated with higher immune activation in infected women. Nature Medicine, 15(8): 955-959, 2009.