Richard W. Michelmore, Ph.D.
Professor
Director, Genome Center
4311 GBSF
Davis Campus
530-752-1729
e-mail

Our research is focused on the comparative and functional genomics of disease resistance in plants, particularly Arabidopsis, tomato and lettuce. Our investigations of Arabidopsis involve the large-scale genomic analysis of resistance gene function and evolution in Arabidopsis as well as a comparative genomics analysis of resistance across multiple species. Our studies of disease resistance in tomato focus on structure-function analyses on the resistance gene Pto, Prf and dissection of the Pto-mediated disease resistance signaling pathway. Studies on lettuce and its pathogens includes classical studies of disease resistance, development of detailed genetic maps using molecular markers, studies on transgene expression and characterization of resistance genes at the molecular level. All of these projects are supported by the lab bioinformatics group.

Lab Page: http://michelmorelab.ucdavis.edu/

Sandoya GV, Gurung S, Short DP, Subbarao KV, Michelmore RW, Hayes RW. (2017) Genetics of resistance in lettuce to races 1 and 2 of Verticillium dahliae from different host species Euphytica 2017 213:20

Scaglione D, Reyes-Chin-Wo S, Acquadro A, Froenicke L, Portis E, Beitel C, Tirone M, Mauro R, Lo Monaco A, Mauromicale G, Faccioli P, Cattivelli L, Rieseberg L, Michelmore R, Lanteri S. (2016) The genome sequence of the outbreeding globe artichoke constructed de novo incorporating a phase-aware low-pass sequencing strategy of F1 progeny. Sci Rep. 2016 Jan 20;6:19427.

Yoong FY, O'Brien LK, Truco MJ, Huo H, Sideman R, Hayes R, Michelmore RW, Bradford KJ. (2016) Genetic Variation for Thermotolerance in Lettuce Seed Germination Is Associated with Temperature-Sensitive Regulation of ETHYLENE RESPONSE FACTOR1 (ERF1). Plant Physiol. 2016 Jan;170(1):472-88.

Scaglione D, Reyes-Chin-Wo S, Acquadro A, Froenicke L, Portis E, Beitel C, Tirone M, Mauro R, Lo Monaco A, Mauromicale G, Faccioli P, Cattivelli L, Rieseberg L, Michelmore R, Lanteri S. (2016) Corrigendum: The genome sequence of the outbreeding globe artichoke constructed de novo incorporating a phase-aware low-pass sequencing strategy of F1 progeny. Sci Rep. 2016 May 23;6:25323.

Christopoulou M, McHale L, Kozik A, Reyes-Chin Wo S, Wroblewski T, Michelmore RW. (2015) Dissection of Two Complex Clusters of Resistance Genes in Lettuce (Lactuca sativa) Mol Plant Microbe Interact. 2015 Feb 4.

Simko I, Ochoa O, Pel MA, Tsuchida C, Font I Forcada C, Hayes RJ, Truco MJ, Antonise R, Galeano CH, Michelmore R. (2015) Resistance to downy mildew in lettuce cv. La Brillante is conferred by Dm50 gene and multiple QTLs. Phytopathology. 2015 Apr 27.

Christopoulou M, Wo SR, Kozik A, McHale LK, Truco MJ, Wroblewski T, Michelmore RW. (2015) Genome-Wide Architecture of Disease Resistance Genes in Lettuce G3 (Bethesda) 2015 Oct 8;5(12):2655-69.

Hodgins KA, Lai Z, Oliveira LO, Still DW, Scascitelli M, Barker MS, Kane NC, Dempewolf H, Kozik A, Kesseli RV, Burke JM, Michelmore RW, Rieseberg LH. (2014) Genomics of Compositae crops: reference transcriptome assemblies and evidence of hybridization with wild relatives Mol Ecol Resour. 2014 Jan;14(1):166-77.

Mandel JR, Dikow RB, Funk VA, Masalia RR, Staton SE, Kozik A, Michelmore RW, Rieseberg LH, Burke JM4. (2014) A target enrichment method for gathering phylogenetic information from hundreds of loci: An example from the Compositae. Appl Plant Sci. 2014 Feb 6;2(2).

Pearl SA, Bowers JE, Reyes-Chin-Wo S, Michelmore RW, Burke JM1. (2014) Genetic analysis of safflower domestication. BMC Plant Biol. 2014 Feb 6;14:43.

Matvienko M, Kozik A, Froenicke L, Lavelle D, Martineau B, Perroud B, Michelmore R. (2013) Consequences of normalizing transcriptomic and genomic libraries of plant genomes using a duplex-specific nuclease and tetramethylammonium chloride. PLoS One. 2013 8(2), e55913.

Truco, M. J., Ashrafi, H., Kozik, A., van Leeuwen, H., Bowers, J., Wo, S. R. C., Stoffel, K., Xu, H., Hill, T., Deynze, A. V., & Michelmore, R. W. (2013) An Ultra High-Density, Transcript-Based, Genetic Map of Lettuce G3: Genes| Genomes| Genetics. 2013

Jenni S, Truco MJ, Michelmore RW. (2013) Quantitative trait loci associated with tipburn, heat stress-induced physiological disorders, and maturity traits in crisphead lettuce. Theor Appl Genet 2013 Sep 28. [Epub ahead of print]

Pandey, M.K., Monyo, E., Ozias-Akins, P., Liang, X., Guimar?es, P., Nigam, S.N., Upadhyaya, H.D., Janila, P., Zhang, X., Guo, B., Cook, D.R., Bertioli, D.J., Michelmore, R., Varshney, R.K. (2012) Advances in Arachis genomics for peanut improvement. Biotechnology Advances. 2012 30:639-651.

Lai, Z., Kane, N.C., Kozik, A., Hodgins, K.A., Dlugosch, K.M., Barker, M.S., Matvienko, M., Yu, Q., Pearl, S.A., Bell, G.D.M., Turner, K.G., Zou, Y., Guggisberg, A., Adams, K.L., Anderson, J.V., Horvath, D.P., Kesseli, R.V., Burke, J.M., Michelmore, R.W. (2012) Genomics of Compositae weeds: EST libraries, microarrays, and evidence of introgression. Am. J. Bot. 2012 99: 209?218.

Uwimana, B., Smulders, M.J.M., Hooftman, D.A.P., Hartman, Y., Jansen, J., McHale, L.K., Michelmore, R.W., Visser, R.G.F., van de Wiel, C.C.M. (2012) Crop to wild introgression in lettuce: following the fate of crop genome segments in backcross populations. BMC Pl. Biol. 2012 12:43

Argyris J, Truco MJ, Ochoa O, McHale L, Dahal P, Van Deynze A, Michelmore RW, Bradford KJ. (2011) A gene encoding an abscisic acid biosynthetic enzyme (LsNCED4) collocates with the high temperature germination locus Htg6.1 in lettuce (Lactuca sp.). Theor Appl Genet. 2011 122(1):95-108.

Simko, I., Hayes, R.J., Truco, M.-J., Michelmore, R.W. (2011) Mapping a dominant negative mutation for triforine sensitivity in lettuce and its use as a selectable marker for detecting hybrids. Euphytica 2011 182:157-166. doi:10.1007/s10681-011-0407-0.

Hayes, R.J., McHale, L.K., Vallad, G.E., Truco, M-J., Michelmore, R.W., Klosterman, S.J., Maruthachalam, K., Krishna V. Subbarao, K.V. (2011) The inheritance of resistance to Verticillium wilt caused by race 1 isolates of Verticillium dahliae in the lettuce cultivar La Brillante. Theor. Appl. Genet. 2011 DOI 10.1007/s00122-011-1603-y.

Cantu D, Vanzetti LS, Sumner A, Dubcovsky M, Matvienko M, Distelfeld A, Michelmore RW, Dubcovsky J. (2010) Small RNAs, DNA methylation and transposable elements in wheat. BMC Genomics. 2010 11:408.

Cui X, You N, Girke T, Michelmore R, Van Deynze A. (2010) Single feature polymorphism detection using recombinant inbred line microarray expression data. Bioinformatics. 2010 26(16):1983-9.

Simko, I., Pechenick, D.A., McHale, L.K., Truco, M.J., Ochoa, O.E., Michelmore, R.W., Scheffler, B.E. (2010) Development of molecular markers for marker-assisted selection of dieback disease resistance in lettuce (Lactuca sativa). Acta Horticulturae. 2010 859:401-408.