M.D./Ph.D. student publications
Jolene Chang
Meffert MK, Chang JM, Wiltgen BJ, Fanselow MS, Baltimore D. "NF-kappa B functions in synaptic signaling and behavior." Nat Neurosci. 2003 Oct;6(10):1072-8. Epub 2003 Aug 31. Erratum in: Nat Neurosci. 2003 Dec;6(12):1329.
Yu-Ming Chang
Chang YM, Yang JC, Evans CP, Kung HJ. Evaluation of IL-8 in Facilitating Androgen Independent Growth in CWR22Rv1 Prostatic Cancer Cell Line. Journal of Investigative Medicine, Vol. 52, #1
Chang YM, Kung HJ, Evans CP. February 2007. "Nonreceptor Tyrosine Kinases in Prostate Cancer". Neoplasia. Volume 9-2, February, p90-100.
Chang YM, Bai LF, Yang JC, Kung HJ, Evans, CP. "AZD0530 is a Novel Src Inhibitor with Anti-Proliferation and Anti-Migration Properties in Prostate Cancer". In press.
Heather Collins-Schramm
Seldin MF, Morii T, Collins-Schramm HE, Chima B, Kittles R, Criswell LA, and Li H (2004) Putative Ancestral Origins of Chromosomal Segments in Individual Africa Americans: Implications for Admixture Mapping. Genome Res. 14(6):1076-84.
Collins-Schramm HE, Chima, B., Morii, T., Wah, K., Figueroa, Y., Criswell, L.A., Hanson, R.L., Knowler, W.C., Silva, G., Belmont, J.W., and Seldin, M.F. (2004) Mexican American Ancestry-Informative Markers: Examination of Population Strucutre and Marker Characteristics in European Americans, Mexican Americans, Amerinidians and Asians. Human Genetics 114(3):263-71.
Collins-Schramm HE, Chima B, Operario DJ, Criswell LA, and Seldin MF (2003) Markers informative for ancestry demonstrate consistent megabase-length linkage disequilibrium in the African American population. Human Genetics 113(3): 211-9.
Collins-Schramm HE, RA Kittles, DJ Operario, JL Weber, LA Criswell, RS Cooper, and MF Seldin (2002) Markers that discriminate between European and African ancestry show limited variation within Africa. Human Genetics 111:566-569.
Collins-Schramm HE, Phillips CM, Operario DJ, Lee JS, Weber JL, Hanson RL, Knowler WC, Cooper R, Li H, Seldin MF (2002) Ethnic difference markers for use in mapping by admixture linkage disequilibrium. American Journal of Human Genetics 70:737-75.
Wong W, Cavelier L, Collins-Schramm HE, Seldin MF, McGrogan M, Savontaus M, Cortipassi GA (2002) Differentiation-specific effects of LHON mutations introduced into neuronal NT2 cells. Human Molecular Genetics 11(4): 431-438.
Collins-Schramm HE, Li H, Inda SE, Anderson J, Laiho K, Tuomilehto J, Seldin MF (2000) A simple and accurate method for determination of microsatellite total allele content differences between DNA pools. Human Genetics 106:218-226.
Patricia Duong-To
Cheung ATW, Driessen B, To PL, Chan DM, Ramanujam S, Barbosa MA, Chen PCY, Jahr JS, and Gunther RA. Comparison of treatment modalities for hemorrhagic shock. Artificial Cells, Blood Substitutes, and Immobilization Biotechnology 2006; 35:1-18.
Cheung ATW, Duong PL, Driessen B, Chen PCY, Jahr JS, and Gunther RA. Systemic function, oxygenation and microvascular correlation during treatment of hemorrhagic shock with blood substitutes. Clinical Hemorheology and Microcirculation 2006;34:(1-2):325-334.
Cheung AT, Driessen B, Jahr JS, Duong PL, Ramanujam S, Chen PC, Gunther RA. (2004) Blood substitute resuscitation as a treatment modality for moderate hypovolemia. Artificial Cells Blood Substitutes & Biotechnology 32(2). 189-207.
Cheung ATW, Ramanujam S, Duong PL, Larkin EC, and Chen PCY. (2002) A real-time study on the microcirculation in type-2 diabetes mellitus (T2DM) and hypertension (HTN). In Microcirculation and Vascular Biology (22nd Meeting of the European Society for Microcirculation) Monduzzi Editore International Proceedings 71-74.
Cheung ATW, Jahr JS, Duong PL, Driessen B, and Gunther RA. (2002) A quantitative study on microvascular changes in hypovolemia and resuscitation treatment. In Microcirculation and Vascular Biology (22nd Meeting of the European Society for Microcirculation) Monduzzi Editore International Proceedings 165-168.
Cheung AT, Chen PC, Larkin EC, Duong PL, Ramanujam S, Tablin F, Wun T. (2002) Microvascular abnormalities in sickle cell disease: A computer-assisted intravital microscopy study. Blood. 99(11). 3999-4005.
Cheung AT, Price AR, Duong PL, Ramanujam S, Gut J, Larkin EC, Chen PC, Wilson DM. (2002) Microvascular abnormalities in pediatric diabetic patients Microvascular Research. 63(3). 252-258.
Cheung AT, Jahr JS, Driessen B, Duong PL, Chan MS, Lurie F, Golkaryeh MS, Kullar RK, Gunther RA. (2001) The effects of hemoglobin glutamer-200 (Bovine) on the microcirculation in a canine hypovolemia model: A noninvasive computer-assisted intravital microscopy study Anesthesia & Analgesia. 93(4) 832-838.
Ramy Hanna
Hanna RL, Kaufman MP. (2004) Activation of thin-fiber muscle afferents by a P2X agonist in cats. J Appl Physiol. Mar;96(3):1166-9.
Hanna RL, Kaufman MP. (2003) Role played by purinergic receptors on muscle afferents in evoking the exercise pressor reflex. J Appl Physiol. 94(4):1437-45.
Hanna RL, Hayes SG, Kaufman MP. (2002) alpha,beta-Methylene ATP elicits a reflex pressor response arising from muscle in decerebrate cats. J Appl Physiol 93(3):834-41.
Manu Hegde
Palandoken H, By K, Hegde M, Harley WR, Gorin FA, Nantz MH. (2005) Amiloride Peptide conjugates: prodrugs for sodium-proton exchange inhibition. J Pharmacol Exp Ther. 312(3):961-7.
Hegde M, Roscoe J, Cala P, Gorin F. (2004) Amiloride kills malignant glioma cells independent of its inhibition of the sodium-hydrogen exchanger. J Pharmacol Exp Ther. 310(1):67-74.
Philbert Huang
Huang P, Gupta MC, Sarigul-Klijn N, Hazelwood S. (2006) Two In Vivo Surgical Approaches for Lumbar Corpectomy Using Allograft and a Metallic Implant: A Controlled Clinical and Biomechanical Study. The Spine Journal 2006 Nov-Dec;6(6):648-58. Epub 2006 Oct 11
Peyman Golshani
Golshani P, Liu XB, Jones EG (2001) Differences in quantal amplitude reflect GluR4- subunit number at corticothalamic synapses on two populations of thalamic neurons. Proceedings of the National Academy of Sciences of the United States of America 98(7):4172-7.
Golshani P, Jones EG (1999) Synchronized paroxysmal activity in the developing thalamocortical network mediated by corticothalamic projections and "silent" synapses. Journal of Neuroscience 19(8):2865-75.
Golshani P, Warren RA, Jones EG (1998) Progression of change in NMDA, non-NMDA, and metabotropic glutamate receptor function at the developing corticothalamic synapse. Journal of Neurophysiology 80(1):143-54.
Warren RA, Golshani P, Jones EG (1997) GABA(B)-receptor-mediated inhibition in developing mouse ventral posterior thalamic nucleus. Journal of Neurophysiology 78(1):550-3.
Golshani P, Truong H, Jones EG (1997) Developmental expression of GABA(A) receptor subunit and GAD genes in mouse somatosensory barrel cortex. Journal of Comparative Neurology 383(2):199-219.
Brian Jonas
Goodson M, Jonas BA, Privalsky MA. Corepressors: Custom tailoring and alterations while you wait. Nucl Recept Signal. 2005; 3:e003.
Goodson ML, Jonas BA, Privalsky ML. Alternative mRNA splicing of SMRT creates functional diversity by generating corepressor isoforms with different affinities for different nuclear receptors. J Biol Chem. 2005 Mar 4;280(9):7493-503.
Jonas BA, Privalsky ML. SMRT and N-CoR corepressors are regulated by distinct kinase signaling pathways. J Biol Chem. 2004 Dec 24;279(52):54676-86.
Jonas BA, and Privalsky ML 2004. Differential Regulation of Nuclear Corepressor Proteins, Silencing Mediator of Retinoic Acid and Thyroid Hormone Receptors (SMRT) and Nuclear Corepressor (N-CoR). Journal of Investigative Medicine 52,1: Abstract #385
Randie Kim
Crowe DL, Kim R, Chandraratna, RA. (2003). Retionic acid differentially regulates cancer cell proliferation via dose-dependent modulation of the mitogen-activated protein kinase pathway. Mol Cancer Res. May 1 (7):532-40.
Crowe DL, Kim R. (2002). A phosphorylation defective retinoic acid recepetor mutant mimics the effect of RA on EFGR mediated AP-1 expression and cancer cell proliferation. Cancer Cell International. 2:15.
Crowe DL, Brown, TN, Kim, R, Smith SM, Lee, MK. (2000). A c-fos/Estrogen receptor fusion protein promote cell cycle progression and proliferation of human cancer cell lines. Mol Cell Biol Res Commun. 3(4):243-8.
Crowe DL, Vo, HP, Chang, LS, Sangalang, B, Osaseri, U, Kim, R. (1999). Retinoic acid receptors in cancer biology. Recent Research Developments in Cancer. 1:1.
Claudia Krispel
Keresztes G*, Martemyanov KA*, Krispel CM*, Mutai H, Yoo PJ, Maison SF, Burns ME, Arshavsky VY, Heller S. (2004) Absence of RGS9.Gbeta5 GTPase-activating complex in photoreceptors of the R9AP knockout mouse. J Biol Chem. 279(3):1581-4
Krispel CM, Chen C-K, Simon MI, Burns ME (2003) Prolonged photoresponses and defective adaptation in rods of Gb5-/- mice. J Neurosci. 23(18):6965-6971.
Krispel CM, Chen C-K, Simon MI, Burns ME (2003). Novel form of adaptation speeds G protein cascade deactivation in retinal rods. J Gen Physiol. 122(6):703-12.
Nelson AB, Krispel CM, Sekirnjak C, du Lac S, (2003) Long-lasting increases
in intrinsic excitability triggered by inhibition. Neuron 40:609-620.
Krispel CM, Chen C-K, Simon MI, Burns ME, (2003), Prolonged photoresponses and defective adaptation in rods of G?5-/- mice, J. Neurosci. 23(18):6965-6971.
Nelson AB, Krispel CM, Sekirnjak C, du Lac S, (2003) Long-lasting increases in intrinsic excitability triggered by inhibition, Neuron 40:609-620.
Krispel CM, Chen C-K, Simon MI, Burns ME, (2003) Novel form of adaptation speeds G protein cascade deactivation in retinal rods, J Gen Physiol. 122(6):703-12.
Lawrence Low
Liu XB*, Low LK*, Jones EG, and Cheng HJ. 2005 Stereotyped axon pruning via plexin signaling is associated with synaptic complex elimination in the hippocampus. J Neurosci 25(40), Oct, 9124-34.
Low LK and Cheng HJ. 2005 A little nip and tuck: axon refinement during development and axonal injury. Curr Opin Neurobiol 15(5), Oct, 549-56.
Joyce Ma
Schrot, R.J., Ma, J.H., Greco, C.M., Arias, A.D., Angelastro, J.M. (2007) Organotypic Distribution of Stem Cell Markers in Formalin-Fixed Brain Harboring Glioblastoma Multiforme, Journal of Neuro-Oncology, In Press
Wang J., Ma, J.H., Giffard, R.G. (2005) Overexpression of Copper/Zinc Superoxide Dismutase Decreases Ischemia-like Astrocyte Injury, Free Radic Biol Med. Apr 14;38(8):1112-8.
Shiloh Martin
Tuscano JM, Martin S, Song K, Wun T. (2005) B cell reductive therapy in the treatment of autoimmune diseases: A focus on monoclonal antibody treatment of rheumatoid arthritis. Hematology. 10(6): 521-527.
Edward Medina
Medina EA, Afsari RR, Ravid T, Castillo SS, Erickson KL, Goldkorn T. (2005) Tumor necrosis factor-{alpha} decreases Akt protein levels in 3T3-L1 adipocytes via the caspase-dependent ubiquitination of Akt. Endocrinology 146(6):2726-35.
Tzipora Goldkorn, Tommer Ravid and Edward A. Medina [H.J. Forman, J. Fukoto, and M. Torres (eds.)], Signal Transduction by Reactive Oxygen and Nitrogen Species: Pathways and Chemical Principles, ©2003, Kluwer Academic Publisher.
Ravid T, Tsaba A, Gee P, Rasooly R, Medina EA, Goldkorn T. (2003) Ceramide accumulation precedes caspase-3 activation during apoptosis of A549 human lung adenocarcinoma cells. Am J Physiol Lung Cell Mol Physiol. 284(6):L1082-92.
Medina EA, Erickson KL, Stanhope KL, Havel PJ. (2002) Evidence that tumor necrosis factor-alpha-induced hyperinsulinemia prevents decreases of circulating leptin during fasting in rats. Metabolism 51(9):1104-10.
Erickson KL, Medina EA, Hubbard NE. (2000) Micronutrients and innate immunity
Journal of Infectious Diseases 182: S5-S10 Suppl.
Medina EA, Horn WF, Keim NL, Havel PJ, Benito P, Kelley DS, Nelson GJ, Erickson KL (2000) Conjugated linoleic acid supplementation in humans: Effects on circulating leptin concentrations and appetite. LIPIDS 35 (7): 783-788.
Medina EA, Stanhope KL, Mizuno TM, Mobbs CV, Gregoire F, Hubbard NE, Erickson KL, Havel PJ (1999) Effects of tumor necrosis factor alpha on leptin secretion and gene expression: relationship to changes of glucose metabolism in isolated rat adipocytes International Journal of Obesity 23 (8): 896-903.
Noah Merin
Pagelier NM, Vinod Menon, Merin NM, Eliez S, Brown WE, Reiss AL. (2005) Dissociating Fusiform Gyrus and Superior Temporal Sulcus Involvement in Face and Gaze Processing. NeuroImage (In Press)
Manning BH, Merin NM, Meng ID, Amaral DG. (2001) Reduction in opiois- and cannabinoid-induced antinociceeption in rhesus monkeys after bilateral lesions of the amygdaloid complex. J Neurosci 21(20):8238-46
Karen Mu
Nie, L., Gratton, M.A., Mu, K.J., Dinglasan, J.N., Feng, W., and Yamoah, E.N. Expression and functional phenotype of mouse ERG K+ channels in the inner ear: potential role in K+ regulation in the inner ear. Journal of Neuroscience. 2005 September 21;25(38):8671-9.
Ekama Onofiok
Szumigala RH, Onofiok E, Miller R. (2005) Mild non-transition metal catalyzed deprotection of N-allyloxycarbonyl amines, Tetrahedron Letters 46(25):4403- 4405.
Waters, M; Onofiok E; Tellers, D; Chilenski, J; Song, Z.
Enantioselective Synthesis of 1,4-Dihydrobenzoxathiins via Sulfoxide-Directed Borane Reduction, Synthesis 2006: (20) pp 3389-3396.
Anna Peter
Niazi KR, Ochoa MT, Sieling PA, Rooke NE, Peter AK, Mollahan P, Dickey M, Rabizadeh S, Rea TH, Modlin RL. Activation of human CD4(+) T cells by targeting MHC class II epitopes to endosomal compartments using human CD1 tail sequences. Immunology. 2007 Jul 16; [Epub ahead of print] PMID: 17635609 [PubMed - as supplied by publisher]
Maude Vance
Vance MM. Baulch JE. Raabe OG. Wiley LM. Overstreet JW (2002) Cellular reprogramming in the F3 mouse with paternal F0 radiation history. International Journal of Radiation Biology 78(6):513-26.
Vance MM. Wiley LM (1999) Gap junction intercellular communication mediates the competitive cell proliferation disadvantage of irradiated mouse preimplantation embryos in aggregation chimeras. Radiation Research 152(5):544-51.
Ingrid Wertz
Wertz IE, O'Rourke KM, Zhou H, Eby M, Aravind L, Seshagiri S, Wu P, Wiesmann C, Baker R, Boone DL, Ma A, Koonin EV, Dixit VM. (2004) De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-kappaB signalling. Nature 430(7000):694-9.
Wertz IE, O'Rourke KM, Zhang Z, Dornan D, Arnott D, Deshaies RJ, Dixit VM. (2004) Human De-etiolated-1 regulates c-Jun by assembling a CUL4A ubiquitin ligase.
Science 303(5662):1371-4.
Zhou H, Wertz I, O'Rourke K, Ultsch M, Seshagiri S, Eby M, Xiao W, Dixit (2004) VM Bcl10 activates the NF-kappaB pathway through ubiquitination of NEMO.
Nature 427(6970):167-71.
Dornan D, Wertz I, Shimizu H, Arnott D, Frantz GD, Dowd P, O'Rourke K, Koeppen H, Dixit VM. (2004) The ubiquitin ligase COP1 is a critical negative regulator of p53.
Nature 429(6987):86-92.
Wertz IE, Hanley MR (1996) Diverse Molecular Provocation of Programmed Cell Death. Trends in Biochemical Sciences, 21(10):359-364.
Wertz IE, Deitch AD, Edwards, R, Gumerlock, PH, Chi, S-G, deVere White, RW (1996) Correlation of Genetic and Immunodetection of TP53 Mutations in Malignant and Benign Prostate Tissues. Human Pathology, 27(6):573-580.
Fred Wu
Wu F, Jagir M, Powell JS (2003) Long-term Correction of Hyperglycemia in Diabetic Mice after Implantation of Cultured Human Cells Derived from Fetal Pancreas. Pancreas 29(1):e23-9.
Clark GM, Osborne CK, Levitt D, Wu F, Kim NW (1997) Telomerase activity and survival of patients with node-positive breast cancer.", J Natl Cancer Inst. 89:1874-81.
Kim NW, Wu F (1997) Advances in quantification and characterization of telomerase activity by the telomeric repeat amplification protocol (TRAP).Nucleic Acids Res. 25(13):2595-7.

