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Health Management and Education

Health Management and Education

Pills for diabetes

Drug Name  Brand Name  Doses Available (mg) 
Pioglitizone Actos® 15, 30, 45
Rosiglitizone Avandia® 2, 4, 8

These drugs are members of the thiazolidinediones “TZDs” (insulin sensitizers) class.

How thiazolidinediones “TZDs” work

  • Primarily works on muscle, fat and liver
  • Improves how the body uses insulin
  • Decreases the amount of glucose released by the liver

Guidelines for use

  • Taken with or without food
  • May be prescribed with other medications for treatment of diabetes

What to do if a dose is forgotten

  • You can take your dose later in the day
  • Do not take 2 doses the next time

Side effects

Side effects may occur when starting a medication but will often lessen once your body is used to the medication.

  • Headache, backache, fatigue
  • Swelling or fluid retention
  • Generally does not cause low blood sugar (may if taken with insulin)

Who should NOT take this medication

  • People with liver disease
  • Pregnant women

People taking this medication must have regular liver function tests.